VALUE OF VITAMIN B1 IN ACUTE POISONING BY CYANIDES

Document Type: 
Collection: 
Document Number (FOIA) /ESDN (CREST): 
CIA-RDP80-00809A000600300488-7
Release Decision: 
RIPPUB
Original Classification: 
S
Document Page Count: 
1
Document Creation Date: 
December 22, 2016
Document Release Date: 
September 7, 2011
Sequence Number: 
488
Case Number: 
Publication Date: 
April 27, 1950
Content Type: 
REPORT
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PDF icon CIA-RDP80-00809A000600300488-7.pdf36.66 KB
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Sanitized Copy Approved for Release 2011/09/08: CIA-RDP80-00809A000600300488-7 LANGUAGE COUNTRY USSR SUBJECT Scientific - Toxicology, vitamins HOW PUBLISHED , monthly periodical WHERE PUBLISHED Moscow DATE PUBLISHED May 1948 CLASSIFICATION SECRET SECRET CENTRAL INTELLIGENCE AGENCY C REPORT INFORMATION FROM FOREIGN DOCUMENTS OR RADIO BROADCASTS CD NO. DATE OF INFORMATION 1948 MIN NMUNNNT CONTAIN. INro.NAT1.N AIT[CTIxr TM[ NANNMAL Quart Or Txr UNITED AATU NITNIN THE EDDIM o1 prINN Wr ACT r N. r. .31 ANN bLAI A., NNr N. It. LAAAN SRINN 0A lxr N[YNLATION or m coxnxrr IN AN ANNCN To Ax u Aurxoruro rmox a rro xurtco n LAW. nnocucn IS or Txn . IS rroxuino Farmakologiya i Toksikologiya, Vol XI, No 5, 1948. VALUE OF VITAMIN Bt IN ACUTE POISONING BY CYANIDES The author injected thiamine in dogs which were given lethal doses of potassium cyanide. In one series of tests, one milligram per kilo- gram weight of thiamine was intravenously and subcutaneously injected 3 minutes and 10 minutes, respectively, prior to intravenous injections of 3 milligrams per kilogram weight of potassium cyanide in these dogs. No fatal results occurred in these tests. Intravenous injection of 1-2 milligrams per kilogram weight of thia- mine one minute after the injection of 3 milligrams per kilogram weight potassium cyanide prevented death in two out of five cases. Thus, the beneficial activity of vitamin B1 in severe poisoning by cyanides is successfully established. It is recommended that this vitamin be made available to those people who are exposed to the danger of cyanide poisoning. STATE ARMY - 1 - CLASSIFICATION SECRETSECRET Sanitized Copy Approved for Release 2011/09/08: CIA-RDP80-00809A000600300488-7