SCIENTIFIC ABSTRACT YEROZOLIMSKIY, B.G. - YERSHOV, G.S.

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SCIENTIFIC ABSTRACT
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POP, 014 UNCLASSIFIED PROCESS[NG DATE-040-LA:70 ~CIRC ACCESSION NO--AP0141021 'AS.ST.RACT/EXTRACT--(U) GP-0- ABSTRACT. THE VALUE OF THE CUNSTANT D OF THLC TRIPLE CORRELATION BETWEEN THE VECTORS~OF THE NEUTRON SPIN SIGMA ANO THE DIRECTIONS OF THE ELECTRON AND ANTINEUTRINO MOMENTA P SUBE AND P 15 FOUND TO BE MINUS 0.01 PLUS OR MINUSLQ.01* THE 0RRLSPONDING PHASE SHIFT BETWEEN AXIAL VECTOR ANO VECTOR.CONSTANTS OF -THE ~iEAK INTERACTION IS;PHI EQUALS 181,.3 PLUS OR MINUS 1.30E~REES. FACILITY: INST* OF ATOMIC ENERGY, MOSCOW. UINCLASSIFIED MIR 11 ml, I Rul" '11"Iff IN "EM USSR -D -_K0 L. N. MCISTO" Y, Yu. A. OBINYAKOV, B. A. 0! , AREN B I TT 'c Enerp- inen V. urvv,,-,v~ and .-OV, V. A. institute of Atom =,-,i a t o v 11rearch. for --hree-Vector Corre"aton r. din e recay of Folarived Neutrnnsl' Moscow, Yadernaya Flzika, !Vol. 11 No. 5, May 70, Do IGL_I.~_,))S'7 -led to rredsia-e the, constant, of trl:pit, c rrela- Abstracu. An ex~-_r_nent ccnduc C- tweer lie vectors of tine ni~rutrcn sz)in.o and the plec,-ron iind antin,!"tr-ria tion,be t*. momenta. p and p is described. The experiment.was conducted on tl~e ITU-M reactor of th e instItute ol" Atonnic EnerQ~ imorji 1. V. Xulchat--Ov. '23 of measurements of duration 35-100 hours each were conducted and ap-oroximately 9.1- .104 decay events were record(~(]. average value of the aceffIcient D f r n d all series -was -0.01�0.01. The accuracy in obtaining the i,:c sViin L 1) m- dc p -difference between ossible to establish the differunce from _IBOO of the phasli- the axial-vector and the vector constarits of weak- interactlon; this was found to be 181.304--l.30. MASSIVE TILOOU 7PAUMMUS [Artlcla by N. Ya. V,Oik-y And D. P. Ycrz;-,, 3!"C- It r- I ; No MsmiLvo, blood tranat-o4lmiq art. rivr..l To thasc eurriring frm "trnxiV4 BT4 At ly, fu-Jucr the dcath :talks, ~ Atcirroint: 1w eats. GE cromby AN Ookay LOSS), 16 litrk-s f,bloni are vrdasrosvil for Novelro wouf0ii htoa4liie., !4v w1oly"d Cho #rfectLvont*q of tanviivo blood trnnsfusic,ou frur, 1wispical recitedo. A total of 51 Pottent-ii recoLved Auch tratimfuRlonn oytr is jerLvd .-f 10 roaeo,, Lrth va-u tr,taof-ed at une riluo :an nr 1,5 to 2 llleor'~; tmnxi=-= 4,5 literO of blood as an emergency measura. Thirty partniAo reiceived na-,xivr Cirnns;(u4ims ~ for , 'tCUUMaill bleedled and AIJOCIt. Its 01WtAltiM" Ct"~11.Fatcu by aul'stantial. bLiil-466, and 8 durini; enjnr wid rVOCxAzttd opzratl~r.A acc~ pi;nLod by blending, I a' tr-apatw1oru uerv xupplanentipil by intlutioni at dextrah'and oilitir blood Outiatit,Avo (I to A_'), lttcra).,.~ Tha of anawivu pl~4j& trwtwfusixjn~ is facilitattd by t-~e existence lit clat, hompital of a tiepatEmwit for bl*oJ, pct,curelwot And tr"$. Covion. Uue to the teen, fInnor ayqtem ti-ra Lit akwayo a ~ Pupply of 0(l), ACIE). and "(%IT) groups "0" du ty." Donors 4ith kut-n blood. Broups are raiistitrO4 and choy~"; be Awmioncd An a vhprt time it Overa is $Lit scuto need ILr thtle. In view of the Ppor condittoll of the Patitnts, rAsOve tyanafi-vions; were Itencrally 'vorricit oisE by pbjrb,,low-, in 5 raites littruartertAl inivettan of blood won litrorteii under proojure. 116to Clint motive ditect tritnitfs4sion ift Wo,411 difti.;'%llm 6. 144 iltOlk t11'%jVP4k t%Wl~C~AAWO. 6% -It' Offe4tiV". This, Ptollipil way um"d Cow 7 1.4tivAto (500 P.1 en0i) Stier wh1rh it,. pr"q'1,r* waj entiLlouptl with hattkud blowl. rijailive trollitfiJOLCM0 w1w, ofictl given to pittLanta in very pone con,W!,,n, there wiv newt (,,r opt,ol, Wictitacy, ami cnimlitintitin on the pArt, of the wo,lical poronn"al, 'The CrOAtIOn at A regular bluad trattafunion toom mido Ap oL a phytician Arm) I Warman vas An ImpnttAnt faccor, F.Rtbwatu* n( blood 1p;Fes wre based on cliolvAl =4 laboratory incat tho prjt~tAtl# Aotor.il conielition, "not it-uonmk nano' arlori4l reanure , raitpitittionf U~Olabin lirval, qirythrowvtor catint. In nomo Canals LF., 11.attlcrLt And approximato b1nod loss by Vain ill)~kftls hod) weire datottatood, 71 4. lf2 017 -UN( R SSANIG WTI~--J)~JUV70 A IN: .,-~:~j -1 TL El;-'rT irz I SGUlk T I 'C EL 0 i IF ml A D AM, LMUiA'J ULUS RLSMAIJ ~WL;J*GUES ~'GP tilT,:~IIUS `~A A.V~, STGLYAR~.CVAr :L. YERSHEKOVA', YU.YE. CGUNTRY OF I"qFG--USSq 'SOURCE-BYULLETEN' EKSPER I MENTAL gJ40Y B*I0Lf)GI II;4EoITS NY --)7o, VCL 49, 6, PR 91-94 1E 0------- 70 DATE PU8L IS,- IENCES'- --SUB'ECT APE~'S--BIGLOGICAL 4ND MEDICAL St: TOPIC TAGS--TISSUE CULTUkEo TU.MORI. CULT()Ri7 t%JE D I U;.t I ME P Y R I i'l 10 Im F. CCUTRUL 4-tARKING-NO RESTAICTIUNS CLASS- U f I C LA S S I F i E 01 'RE STEP N 0 - - Ilk017U/Oq')/006/0091/0094 PROXY 'EL/FRAME-3001,/0566 CIRC A cc s 5f0,14 c UC LAS S IF IE PROCESSING DAT----13WjV70 /2 017 UNCLASSIFIED CIPC ACCESS101IN NO--~,PD!31189 -A8STkACT;'c-YT-kACT--(U) Gi7-0- ABSTRACT.' THE AUTHORS INVEST[GATED THE CELLS UF~ HLLA.~sk-NU AM-J T Ll-GUES OF SENSITIVITY OF CUT IVATED STRA 1,4S 0 Ai4 N PUR 1 ME AND PYR I M I L) f,,,E 13 ASE S(8-AZAXANTHINt HYPGX'A-.ljTHl.N? Ao~:NINEt -0 lA;lINJPU.RlNE SULF-'TEl Gu 2 9 6 'Aclop V,,'JSlNEi GUANN PlE-?, 3-0 AR IUM PHUSPHAH). , iT IS SHUthl THAT "HELA ANO AA-I CELLS A.R,-- sE,-siriv~ 0,1LY TO .11 - IN E SULFATE. Se' ON Tl i-,F HHA 8-AZAGUANINE AND 2 oIA,- N"Fur'. NE&IS MJTAjNTS C AND Ai-l-I CELLS PFSISTANT TO 8-AIAGUA4,P-4E (IN A CONCENTRATION OF 4 MU ERE SOL ATED 'INST110TE: OF EXPEml-,'~FNT`4L G L) W 1 FACILITY: l0LbGY T I ACAOEMY OF E: U I C' A L:5 C I ENIC E 5l FTHE~ US -S 11 43 s c a UNC L A S S I F f E 0 USSR UDC:536.4.46 YERSHIN, Sh- A RYMLOVA, R. P., SARSENBXYEV, Zh. SlAerody-namics of Gas Streams and a Flame in a Homogeneous Wake (Isobaric and Gradient Flows)'I Probl. Teploenerg. Prikl. Teplofiz. [Problems of Thermal Ilower Engi- neering and Applied Itzat Physics -- Coll,~ction of hlorkfl, No 9, Alma-Ata, Nauka Press, 1973, pp 131-141 (Translated from Referativnyy Zhurnal Aviatsionnyye i Raketnyye Dvigateli, No 11, 1973, Abstract No 11.34.29, from the resuine) 'Translation: Results are discussed from a study of a nonisothermal stream and a- gas flame at high wake-flow parameters. Isobaric and gradient flows are.studied, An explicit expression of the dependence of effective coor- dinate E(x) is produced and introduced inithe method or the equivalent prob- Im from the theory of beat conductivity as a function of the -main flow parameters. The method of the equivalent,problem from the theory of beat conductivity is extended to gradient and jet flows. The results of calcu- lation agree satisfactorily with experimental -results. 5 FigureF; 2 Tables; 11 Biblio. Refs. -1A Heat, Combustion, Detonation USSR LIDC:533.601.1.536.46 YERSHIN, Sh. A., PAK, V.V., SHEGUROV, A. A. "Experimental Study of Aerodynamics of a Diffusion Flame with Supersonic Gas Flow" Piobl. Teploenerg. i Prikl. Teplofiz. [Problems of 1hermal Power Engineer- ing andApplied Heat Physics -- Collection of Works], No 9, Alna-Ata, Naula Press, 1973, pp 112-120 (Translated -from Referativnyy Zhurnal Aviatsionnyye i RaRetn3rye Dvi.nateli, No 11, 1973, Abstract No 11,34.41, from the restiflie) Translation: Ilie case is studied of axis)qnmetrical movement of a super- sonic,streamt and flarne in a flooded space. Experimental data are presented for various cross sections from the cross section of the noztle and for two flow nodes- IkI=l .05, T =9300 K, n=O. 04, and M-.1. 25,~ T =9500 K, n=O. 92. 0 The calculation of thesupersonic difftlSiOn flame is constructed on the basis of the method of the equivalent problem of the theory of heat con- ductivity, and the agreement with experimental, data 's satisfactory. 4 Figures; 9 Biblio. Refs. USSR UDC:533.601.1 USTIMENKO, B. P. TKATSKAYA, 0. S. S11. A. "Some Results of Investigation of the Aerodynamics of a Twisted Gas Flame" Probl. Teploenerg. i. PrikI. Teplofiz. [Problems of Thermal Power Engi- neering and Applied Heat Physics -- Collection of Workr5j, Ne-i 9, Alma-Ata, Nauka Press, 1973, pp 91-99 (Translated from Refcrativii,yy Zhurnal Aviats- ionnyye i Raketnvye Dvigateli, No 11, 1973, Abstract No 11.3-1.42, from the restime) Translation: The regularities of development of turbulent twisted flames are studied with various values of the tivisting parameu!r (0.108>S>0.51) and wake parameter The axial and tangential volocity fields, excess static pressure field and excess temperaturo field are presented in detail. The results of experiments for a slightly tivisted flame are compared with calculated values using the method of the equivalont problem from the theory of heat conductivity and agreement is good. 7 Figures; 4 Biblio. Refs. USSR LM C 621.43.011j4 3+621-51533 53 YWHIM. SM. A. ZHAPBASBAYEV, U. X., MOLYUKOV 1. D. and PAK , V. V. ."The Aerodymamics of Supersonic Flows of a Compressible Gas" Alma-Ata, Vatematika i Mekhanika. Te-sisy Dokl. 4-oy Kinalthstan. Mezhvuz. Nauch. Konf. po Mat. i ],.,ekh, Ch. 2 (1,11atbenatics and.lfechanics.~ Theses of Lectures of the Fourth Kazakhstan Conference of Schoold of Higher Lealming on Mathematics and Mechanics.. Part 2), 1971o pp 203-205 (from Roferativnyy Zhurnal, Mekhanika, No 2, Feb 72#-Abstract No 2B392 by A. S. Tikhotskiy) Translationi The article presents the results of an experimental investAga- tion of a supersonic jet (submerged and with weak cocurrent flow). The installa- tion consi3ted of two coaxial pipes 200 and 400 mm In diameter; on one end of the pipes -were profiled nozzles, one of them with a vent! diameter of 5 mm (a Laval nozzle) and the other irith a vent dimateter of.100 MM, (a Vitoshinskly nozzle). At the other end of the pipes are,fittings for.supplylng air from a system consisting of high-pressure capacities and a fan. The basic regime parameters of the experiments were within the limits of 2 p0 %Z~Z 8 and YW \,;;~ uO \%~Z 600, where po is the pressure.at the Javal-liozzle in-letf u is the discharge velocity from the Laval nozzle. 0 f the jet 1A, It is established that the laws -governing the development o.L USSR "Bloldgical Portents of Earthquakes" Riga, Hauka i Tekhnika, No 4, Apr 71, PP 10-12 Abstract: The 1966 Tashkent and 1948 Ashkhabad earthquakes were preceded by many examples of premonitions of the catastrophe. For example, Ashkhabad hospitals were deluged 6-8 weeks before the quake with people complaining of heart pains. Cardiograms revealed nothing unusual. but Ycirshov suggests that somapeople may be sensitive to such impending events. Ants in Tashkent were observed leaving their nests with the pupae shortly before the quake, and many zoo animals vould not sleep in buildings until the autumn of 1966. Bears in the vicinity of Bezymyannyi volcano in the winter of 1955-56 were impelled to move to safer ground as a result of.impressiQns received from volcanic action. Pheasants in the "Tiger Gorge" gazw proserve'in ToAzhikstan react even to construction going on 15 km away. Soviet scientists are studying the sensitivity of fish to earthquakes. Promising resulti have been achieved by Dr. Protasov of the hydrobionica.group at the Institute of4volutionary Morpholo&7 and Ecology of Animals, Acadimy of Sciences U.S.S.R. Fish are able 1/2 USSR IMHOVj, A., Nauke i Tekhnika, go 4, Apr 71, pp 10-12 to perceive lov-frequency acoustical oscillations arlsing from earthquakes, explosions, and approaching tidal waves. The perception of approaching catastrophes by living organisms,is oftenbased on their hearing sounds not audible to man, which arise when the core of the eart-1, is only beginning 'to "break open." it is also possible that animals react to changes in electro- static and magnetic fields produced by the begi .nning.of an earthquake. There- fore, it is important to make models of an1mals' sensory organs which can per- ceive seismic signals. This vill makeAt possible to opemte without the help of the animalis themselves and to achiciye more r~,llable results. 2/2 USSR :YFRSHOV, A. "The Terrestrial Service of the Sun" Tashkent, Ekonomika i Zhiznl, No 9., Sep 71J. pp 74-76. Abstract: A popular review is presented of efforts to utilize the energy of sunlight for production of the light and~heat needed,by m, The solar con- an. centrators designed by G. Ya. Umarov are.-described. After learning from the mistakes of his first attempt at solar engineering, the construction of a 10-metor parabolic solar reflector to provide the hoal- foil, a canninq plant, Which cracked due to the difference in thermal expansion I)etwceii the glass of. the -reflector and the glue which held it to the ritenforced concrete shape, Umarov ha3 designed many smaller -iolaf concentrators which are now utscd to power pumps bringing water tip from wells in the desert and other similar iso- lated power applications. Another promising application of solar heoting is in metallurgy, where solar heat can melt metals of exceptionally high purity without introducing contaminating impurities resulting~from burning of fuel. Production of such installations~, as wel.l.as hot wate.r:heaters and kitchens -designed for home use, has been begun in Tashkent. TAGS-RADIOACTIVITYP EARTHQUAKE FORECAST9 GEOLOGIC CONFERENCE, EARTH CR U S. TMOVEMENT ZONTRUL MARKING-NO RESTRICTIONS -,..-DOCUMENT, CLASS-UNCLASSIFIED j.~_.PROXY REELIFRAME--1989/0374 STFP ND--UR/9t)29/70/000/000/0004/0004 ~.-CJRC ACCESSION NO--AN0107403 UNCLASSIFIED AIV0403637 Acc. Nr. AUTHORS- MAR.CHUX. G. DEPARTMENT Ref. Code: ACADEMICIAN DEPUTY CHAIRMAN., SIBERTAN ACADEM~ OF scltvas U,S.S.Rpg DOCTOR -OF PHYSICAL-MATHEMATICAL lClZNCESl`9E'A_D'__'0_F A- DEPARTMENT OF~THF.COMPUTATION CENTER TITLE-- COMPREHENSIVE ~PROBLEMS OF ELECTRONIC COMPUTERS NEWSPAPER-- PRAVDA APRIL 9.9 L9709 P 31 COLS 1-3 ABSTRACT- THE ARTICLE URGES A MORE RAPID DEVELOPMENT OF COMPUTER SOFTWARE, TRAINING OF PROGRAMMERS 'AND SHARING OF COMPUTER TIME IN ORDER TO MAKE FULL USE OF HARDWA~I~CAPABILTTIfS. AN AUTOMATED INFORMATION CENTER$ "AIST" 15 BEING TRIED ON EXP:rRl- MENTAL BASIS AT THE COMPUTATION.,CENTER 6F THr:,SlB_rRl'AN BRANCH 6F THE ACADEMY OF SCIENCES, IT.CONSISTS,OF TVO,H-2.20 RAPID COMPUTERS., WHICH ARE CONTROLLED BY THE lvMINSK'22`COMPUTtR,, THE CENTER CA,14 HANDLE SIMULTANEOUSLY 32 SUBSCRIBERS,: Reel/Wrame j.qFia -it Q ng USSR UDO 621. DMITRIYOV, V.G., YERR-,.~ YEDIA, R.A., YERSHOV A.G. I 'KPICKI I.YA., KARFOVA,YE.F. uEngineer-ing Calculation And Opitimiy-ntion. Of Parameters Cf Optical Eurd L Frequonay Doublerv 0, Kvantovaya elektronika (Qluantum, Electronics), IM No )(1l),19Y2, PP 72-79 Abstract. At the con~eynporary leyel. off develapnent as' oxt,orim-:mtal norilinear 'on o4' the pari~- Optics, M-3 necessity for engint.,erinIg calculation and ortimivati mmaters of frequency dDabiers is dictat5d by the appearance of a large number of nonlinvar crystnlL w1hich zz:~tka jJ, poz3siblo to obtain a e-Fficienry ot con- -vers on Into tha secondt vpbical ht~-rmonir, without specill v0 rule, relati7ely sol-it3-state lagrars uro ti2ed ar 'Uht: oollrewi of irliti-fl The radicttion, of the laserri introdimio a ptllj~-..(j orzill the fl-!-ver~Sence sub!:,tantially uxc~~c-ds tho dif):1-adi.c.11 Tjvxhl~ CUIC"11- ation cf frequency da~iblerrol' suan lasers it is rii~cevzmry of the re3ation to take into acco~int both the pulse churacter 0-11' th.:! initj,~-l and thot effec4 c44 cf," Lt~e harmonic. Claltulatlon of:th~; factors i-,I6rofuc!5s a riumber & opecial features in tha. hature (.)-f- th;~-, caloulut- ion of the efficiency of conversion, such as detertrinal.--:on of Mine opluiimjll~ -ra-Lici 1/2 Mim- WOR"I MUNUMUMM1111M ~-1---,_ ~, ~. -- .j M 2 ~66 I A- W" 1 W"M M I:Z~ IISSR RMIUMEV V. G., et al., Kvmmtc~vaya elelftro-Lika, WO 5(11), 10;72, Im 72 '7~, betweeri -Uhe intensity,-, of the exciting irave a-nd the len;,I:i of t',-- Pmlint%a, ta-i, avid ot',ers. The methods, o-P calculation nse' Jn thc pi%z!sent world doveloped by others for the case & a preacribed flelct of initial and for OL nub3tsntially nonlinear rer-Ime, ear d' moiA advisable to conduct mmerical inte.,grotion of equ.~-it--`ono b~ctkuze methods of celculation, valid irL gome approximations,, I-ead to fairly awkward aolut4ons. fiL,. 1 t!ib. 11 ref'. Receivad bv~ ~editor-P.,6Cc'. 1071, 2/2 USSR UD c 621. 145 - 6 -ICIEN SHARIF, G. A. CHERMN 0. B. "An Exneriment-a-I Study of a Laser Based, on a Solutinn of an Organic Dye. With Transverse Pumping a-lid a Dispersion CaNlIty" Zb. prikl. sTektlroskonii. Ocurnal of Applied SpectroscoRv) 19-fl, 14, .11o 2, pp 216-221 (from RZI-R-adlotekhnika., No 7, Jul 71, Abstract N o 7D187) Trarslation: The authors study the polarization, energnr spectral characteristics of emission from a !as-er based on. a solutior~ of rhoda- mine 6G ta ethyl alcohol vith a concentva~tioa of* C = 1-1017 c-M-3. The use of a disT)ersion cav-ity xq---,'th diffraction ftratixu.~ band nrism, r and with transverse pwirjing of the dye by the second h.41111110r.11C of an 8 M'U neod~~jrdwa I-aser made it 'Dossible to achieve eirdasion ihich c,-n be -tuned over a rwng -620 im, with = emisc~iori b~;ffldvridth of ~e a f 5 60 1-6 nm and a maxintm convt--rsic)n factor of. n Fi*;e bibiliograpriy of nine titles. :isi USSR UDC: 62l.373:536.145.6 DMTRIYEV, V. G., YERSHOV, A. G. ZUDKOV, P. I. SHARIP, G. A., SHVOM, Ye. M. "Emission oil Optical Harmonies in the Pulse Mode With a Hik~h Pulse Repetition Frequency" V sb. Kvant. elektronika (Quantum Electronics"i-collection of works), No 1, Moscaw, 1971, pp 116-3-19 (from RZh-Radiotekhnika., No 5, May 71, Abstract No 5D174) Translation: The Daper presents the results of an experiment on generation of the second, third and fourth optical harmonics of emission from an altuninulp, -yttrium garnet laser with neadymium,working in.the pulse- mode*with Q-svitching at a high pulse repetition frequency. It.is noted -that the intensity of ultra- violet emission on a -wavelength of 266 millimicrons,is,eitremely,stable. One illustration, one table, bibliography of eight titles. ~Resum'e. USSR UDC 621.375.82 DMITRIYEV, V. G., YERSHOV, A. G., ZUDKOV, P. 1.1 SHARIr, G. A., SPI10M, Ye. M. "Generation of Optical Har=-nics n a Pulsed Mode With a High Pulse Repetition Frequency" V sb. Kvant. elePL-ronika (Quantum Electronics),,14o. 1, Moscow, 1971, pp 116-119 (fran RZh-Fizika, No 7, jul 71, Abstract No 7D996) Translation: The generation of second, third, and fourth optical harmonics of the radiation of a YAG:Nd laser operating in a pulsed mode with Q-modulation with a high pulse repetition frequency was,investigated ckperimentally. There was.found a high stability of ultraviolet radiation intensity at:the wavelength 266 rim. Authors abstract. 48 USSPI ITDC 621.357.12.035.2 GAVRILOV, B. A. RYAMMINS Al. G. I YER-11-Ov -2 GRISHAYENK P B. G.1 -later.in an Electrolytic Cell "OpUmal Current Density for Decomposition of with Porous Nickel Electrodes" it, iii-ta (Works of the Nurgan Machine Buildin- Iiistitute) -in. viashinostro Tr.. Kurg, 1971, vyp. 17, pp 70-73 (from R23i-Kiiiniya, 111o 6 (11), Jul! 72, Abstract 'No 61.258) Translation: A study was nade of the effect of the temperature oil the magnitude of the dimensional D for electrolysis of water in a cell with porous electrodes. ..It was established tnat Lhere is a region of -optirml size, 1) which e.Tands with all increase in temperature an(] is 3.1111ited an the one hand by the conversion of the anode frov, the pas3l,ve state to the, active state accojq).ln1,ed by strong he ix-mproductive lopses. corrosion and, o-a the otber hand, by:a sharp: Nervaim 1.11 t V~P !JSSR YF.R__SLOY,A~_,R,_, KOTOV, V. Ye. ,LETICIIEVSKIY, A. A., PODLOVOIENKO, R. I., POMSIN, I. V., TRAKHTENBROT, V. A., FUKSMN, A. L. and, TSEYTIN, G. S. I"Eheoretical Programming in the USSR (All-Union Symposium on Programming Theory, Tsitelodubovo, 1-10 March 1972)" Sistemnoye i Tear. Programmirovaniye (Systems and Theoretical Programming Collection of Works], Novosibirsk, 19,72, pp 9-89 (Translated from Referativnyy Ziturnal Kibernetika, No 9, 1973, Abstract No 9V642). Translation: This article is a collective report of the chairmen of the thematic scctions of an All-Union symposium on progxamming theory held 1-10 March 1972 near Leningrad.. Although only factual ma,terial discussed at the s"posium is presented, this publication rather objectively charac- terizes the status of theoretical programming -in the USSR. The work of the sy=OSIUM consisted of a series of thematic sessions and.discussion. The following sessions were in operation (each~followed by the name of the chairman): I.- Equivalence and Conversion of Program Plans (A. A. Letichev- skiy); 2. Yanov Plans and 11heir Generalization (R. I. Podlovchenko); 3. 7he Grammars of Programming Languages (A. L. Puksman) ; 4,~ Base. and Semantic 1/2 USSR Yershov, A. P., Kotov, V. Ye., Letichevskiy,,A. A., Podlovchenkc, R. I., Pottosift, 1. V., Trakhtenbrot, V. A., Fuksman, A. L.) and Tseytin, G. S., Sistemnoye i Teor. Programmirovaniye Novosibirsk, 1972, pp 9-89, L2nguages (A. P. Yershov); 5. Parallel Programming (V. Ye. Kotov); 6. Opti- mization of Programs (I. V. Pottosin) ; 7. Complexity of Algorithms and Algorithmic Power (G. S. Tseytin). The session was opened by a speech of introduction by the chairman, followed by 20-30 minute reports by the participants and, generally, finish- ing up with animated discussion. The publication is a combination of the reviews of each of the thematic sessions.of the spnposium, prepared by the chairman of the sessions on the basis of author's abstracts of the reports. In addition to this, a discussion on the subject of "Programming Theory and Other Sections of Mathematics," chaired by B.. A. Trakhtenbrot, is described, as well as the results of statistical processing of question- naires passed out to the participants of the symposium, reflecting their views an the role of programming theory in general and the significance of individual sections of this theory. -M, Gorbunov-Posadov V2 USSR YERSHOV, A. P. "Technology of Development of Programing Systems" Sistemnoye i Teor. Programmirovaniye [System and Theoretical Programming Collection of Works), Novosibirsk, 1972, pp 136-184 (Translated from Referativnyy Zhurnal Kibernetika, No 6, 1973..,Abstract No 6V664, by the author). Translation- An attempt is rade to Provide a SIMIHaTY Outline of the primary components of the technological process involved in planning and development of large trans lating-type programming systems. The problems of organization of-work and documentation Lre notcovered in this article. Translation is analyzed as a specific biformationproces .sing.task. The prerequisites foy determination of the structure of a translator are analyzed from the systems ogram, and therefore The translator is looked upon-as a large pr approaches to its programming and debugging are preseRtod. The concept of the machine. is introduced, combini-W:all'problems of "witomation of the devel- opment and actual realization of a system. 104 biblio. refs. USSR YE "A Unive rsal Progrwmiing Processor" Probl. Prikl. Mat. i Mekh. [Problems ~of Applied Mathematits and Mechanics Collection: of Works] , Moscow,~ Nauka, Press, 1971, :pp 10:~--116., (Translated from Referati"yy Zhurnal, Kibernetika,,No 3~ .1972, Abstific- No 3 V526 by -aitthor) the Translation: An approach is described to the construction of a universal programming processor, capable of translating prograins in such languages as ALGOL 68, PL/I and SIMULA 67, fixed in the rTocessor using 5 types of linguistic tables (contextually free syntax., context conditions and rules, identification, rules of reduction and cemantictinduction, tables of ceman- tic replacement and tables of linguistic situations). One peculiarity of t he process is the presence of an algorithmic internal language used to describe the cemantics of input languages, and forming a level of recording of the translated program , at which universal optimizing, transforms are performed on them. 11 Biblio. Refs USSR UDC: 8.74 [Editorl, "EPSILON, A System for Automation of Programming of Symbol.i.c. Processing Problem" noy Obrabotki. EPSILON- Sistema Avtomati2atsii Programmirovaniya Zadach Simboll. rsk, Nauka Press, 1972, 132 pp ( ranslated [English version above], Novosibi T No lIV534K, by from Referativnyy Zhurnal Kibernetika, No 11, 1972, Abstract Mikheyev) Translation: A description is presented of the new programming language EPSILON, C, a machine-oriented language designed for description of algorithins for process- ing of symbolic JUnformation. The basic information units permissible in the- t of r language are the machine word, a certain sc sequential machine wo d units or syllables and the linear sequence of elements, syllables with identical numbers of characters. The language has a means of identification of certain classes of symbols, as codes. It is assumed that these classes are differenti- ated according to the binary representation~of the symbols in the corresponding class. To account for the influence of the~machine, the description of the language and system of EPSIL04N does not define a unique language, but rather a certain set of languages and systems...Any language in this system has two 112 USSR Yershov, A. P., EPSILON--Sistema Avtomatizatsii Prog-rammirovaniya Zadach Simbollnoy Obrabotk e -i, Novosibirsk, Nauka Pr ss, 1971 132~pp levels--the standard level, definin.cr the properties %which are common for all languages of the set, and the specific level, the similarity or difference of which with other specific levels isnot limited. The syntjLx of the language is basically defined in the standard level, the semantics--botli in the standard and in the specific level. In particular, the semantics of operators at the specific level are determined by the.form of the operator, i.e., the sequence Of instructions of the specific machine which replaces the operator. Using this design of the language, as an instruction and open procedure, the EPSILON systcm can perform the functions of a macroassembler. - The language allows packing of information in A I ist refers to a' cortiiii vector of information linj ts ensely packed into memory. Express* ns in the. language. "irc simple--they coil- d 10 tain not over two operands. Numbers recorded in the language can only be non- negative integers; all other numbers must be introduced im licitly using the p peculiarities of the specific language level. A definition is presented of specific realizations of EPSILON for the M-220, BESM-6 and NIINSK-22 computers, plus information on translation and debugging algorithms~ for th:Ae language. The basic translation algorithms are presented in the form of programs in EPSILON itself., 2/2 ~1112 022 UNCLASSI FIED PRaGESSENG DATE--160CT70 TITLE--THE DETECTION OF HYPERFINE STKUCTURE IN T14E EPR SPECTRUM OF A STRAPPED ELECTRON.IN GAMMA !RRADIATEO ALKALI'NE GLASSY ICE AT 77DEGREE.SK AUTHDR-M)YERSHOVt B.G-t PIKAEV, A.K. r., 0UNTRY OF INFO--USSR 5CURCE-RACIAT. EFF.; 2: 135-61 JAN 1970 OAITE PUBLISHED ---- JAN70 ~O_BJECT AREAS--PHYSICSI MATERIALS TOPIC~ TAGS-- E PR 5P ECTRUMv HYPERFINE. S T.R UIC T.U'R E,,,. LINE SPLITTINGe ELECTRON .._',TRAPPING*.GAMMA IRRADIATION, GLASS PROPE~WY. ~'dNrROL MARK I NG--N0 R E S TR I C T I UNS DOCUAENT ';.LASS--UNCLASSIFIED RRUXY REEL/fRAME-- L9tl5/ 1461 STLP NU-UR/0000/70/002/000/01 ~5/01 36 4tRC- ACC~SSTON NO--AP0101541 UNGLA SS 1 F HE 0 ---- -- - I --- -- ---- - - - - -, ,.bqc L lv~l F H-D-- a ~.:~-11-2 013- UNCL ASS IF I ED:.' PRbC'.E-SSI.NG DATE-02JICT70 TLE-L"'ISS 0F CAPTUiRED ELECTRONS I N' GAMMA I kRADI ATED AL~,AL INE GLASS AT 770E-Gl~~E-FSK 7U- A u r f f) 2 1 Y E P S H-al Y j B.G., T5i:YTLINr. YEeL., N T F,Y U F INFo--USSR VYS. E`qERG. 1970, 4(Z) 186-7 TECHNOLOGY .,.:S.U3tJ,E-Cl AEAS-MATERIALS, NUCLEAR SCIENCE:AND :JiC-PI.C 'TAGS--G-l*MMA RATIATIONv FLECTRON ACCEPTOR, N ITRITE, NITRATE, j- RRAD[AITED GLASS,: ~.FR RUC Y.Af!j CIE ALKALI GLASS, I R GL ;~:~ARK I '-G-- NO E ST R I C T 10' S D0'f'UME-%-T CLASS-UNCLASSIFIED PR31XY k[[LlrkA,*AE--19Q2/I498 STEP NC.--tj'R 104 5 5 70 f0 :~lt GO 2 01.3 0 1 S-7 ~%E- -,`010 112 4,4 -2/2 013 U~XLASSTFIED PROCESS114G OATE--02ncr7O ~CARC A C C E S S I NO-AP0112492 J-0j) GP-0- AF3STRACT. THE 004 LOSS .48ST-ACT/EXTRAC RAN 'F CAPTU~ED ~E L E C T F 6 N-.S ( FPRIME NEGATIVE CAPT), WAS ST UDIED I N TH E PRESENCE DF 'ElECTRON 4CCEPTORS. THE DOSE OF GAMMA KADIATIGN FROM PRIME60 CU WAS 6 TIMES 10 PkIME15 EV-GISCC. THE 43SORPTION MAX. OF E PPI'LlE qEGAT[VE CAPT '(580 INN) DECREASES WITH THE INTRODUCTION OF THE ACCEPTORS \10 SU82 PRIME NEGATIVE, N'J SUB3 PRIME NEGATIV", FE(CIN). SUB6 PRIME~ NEGATIVE. I 'N P U R F ALK. "Ut~SSI- THE ARSOP.11TION OF E PRIME NEGATIVE CAPT REMAINS rDNST. FkIR -SIONE TIME. IN THE PRESENCE OF ACCEPTORS A NOTICEABLE DECRFASE IN THE 'ABSCREANCE IS ORS0. THE RELATIVE DOSE OF THE RANO-OKLY UISAPPEARING E rREASE PRIME NEGATIVE CAPT INCREASES WITH THE ACCEPTOR CONCN. WITH AN IKI JN THE CONTENT OF NU SUB3 PRIME NEGATIVE AND FE(CN): SU56 PRIME3 NEGATIVE FRCHI 5 TIMES 10 PqI ME NEGAT IVE3 TO 5. T I MES , 10 PR I ME. N&GATI VEZ %i I r INCPEASES FROM 8 TO 25 AND FROM' LZ TO-40PERCENIT-i RE'SP. T4AG KINFTICS OF THE LOSS OF ELECTRONS ON THE SE-CT13N OF:,FAST DROP US BEST DESr~IBED BY .,:A.% EQUATIGN.OF THE IST ORDER. THE RATECONSTS. FOR 10 PRIME NEGATIVE2 K 14 U SU133 PRIME NEGATIVF, NO SUB?_.:PRIME-: NEGATIVE, E(r r SU66 pRIME3 ARE 2.4. TIMES 10 PRIME N~GATIVE:2y.~ 3o9: TIMES LO PRIME NEGATIVE_':~v _'--:1.3 'TIMES, 10 PRIME NEGATIVE2 SEC PRIME :NEGAriVEI-i AU-SP. THE RANOOM LOSS T DUE 'n OP E -PRIME NEGATIVE CAPT IN AQ. ALK. "GLASSES". IS APPARI-I'll LY THF- TUi4NEL.TRANSFER OF AN ELECTRO14 T04HE ACCEPTOR. f a mmm, wmmom -1 f 21 026 UNCLAsstr-IM'~ PROCESSING DATE--230CT70 ;T-I-TLE--PHYSICC'AECHANICAL PROPERTIES OF.TRANSLUCENT GLASS FIBER REINFORCED ' STICS~ -U- PLA .,__.UTH,QR--YERSHOVv BoL. lCOUNTRY OF,INFD--USSR 196/9. E--BUDIVELINI MATER. KONSTR, 969t Mt~39-40 C 00~ POL-ISHED ------- 70 AREAS--t-TAT-ERIALS ,j 0 P 11C TAGS -GLASS FIBERr REINFORCED PL:ASTI Ct POLYESTER RES(Nt BOROSILICATE .,..--.GLASS#: -ADHES M/M PN1 POLYESTEVAtSIN -.CGN.TROL MARKING--NO RESTRICTIONS CLASS--UNCLASSIFIED REEL/FRAME--199511477 STEP NO--UR/0635/69/000/004/0039/0040 -'-C-IRC:ACCESSION NO--AP0116914 UNCLASSIFIED -- --. - - -- - -- - - - - Lit - - - - ijUl~~Il- USSR Yt UDC 621.373:590.145.6 BATA\OV, V. A., YERSHOV, B. V.,' MAKSIMOV, L. P., SAVRANSKIY, V. IF., FEDOROV, V. B. "Laser Unit with Radiation Energy up to 10 Kilojoules for Investigating the Inter- action of Powerful Luminous Fluxes with Matter" soobshcheniya po fiz. Kratk. (Brief Reports'on Physics), No 4, 1970, pp 8-14 .,(from RZh-R;idiotekhnika, No 8, Aug 70j Abstract No -9 D188) Translation: This article contains a description of a devLce created on the basis of a neodynium glass laser ( ~1=110,600 generating pulses idth an energy to 10 kilo oules and ~~ I millisecond long. The Intensity of the light flux reaches 10 W atts/cm2 over anarea of tip to 1 cm2. The dovtcc- consisLs of three independent generators oparating in parallel each of which'containn rhree plane- parallel rods of neodynium glass pumped by pulse tubes. Tbe experience in operat- in& the device for three years has demonstrated that obtaining an energy of -10 k1lojoules is possible 5-10 times, oi)taining 4n energy of.five kilojoules is 50 times -without replacing the tubes, active elements and reflectors. USSR UDC 612.7qi.ol4.482 OSANGVJV D. P. J, E. B., KLYKOV, 0. V.,: and IMOVA, V., A. "Kinetics of Dose Distribution in Skin Contaminated by Radioactive Substances" Moscow, Vieditsinskaya Radiologiya, No 5, 1971).pp 44-50 0' SX-89" pu239 nitriites and other radio- Abstract: Solutions of tritium xide, active substances were applied to the backs of 8-week-old pigs (whose skin is morphologically and physiologically almost identical to,human skin) in order to study the kinetics of penetration of the absorbed doses. The distribution of activity was investigated by the method of layer-by-layer radiometry of horizontal sections 15 to 20/U m.thick. The substances.reinained on the skin from 1 hour to 2 days. Date. wereialno.obtainekd:on.the kinetics of elimination of the isotopes from the skiu after a single 6-hour exposure.. A correlation was observed between the absorbed doses.in the basal layer that were foxred by the thin surface contamination and the.thick-layersource created in the skin by penetration of the isotopes through the horny layer., 19 N USSR UDC 576.858.6.083.35.07 ZHD,*IOV, V. M., EYKOVSKIY, A. F., AL'TSHTEYN, A. D., LOMNSKIY, T. F. URYVAYEV, L. V., VOLKOVA, H.. L.,,YERSHOV, F. I., IMM, K.V., BEKTEMIROV, ZAKMOVA:, L. G PEREMST, V. V., T,..A., IRLIN, I. S. . MILLER, G.- G., GERASINA, S. F., and SEWST'YANOVA, M. V. Institut;,of Virology imeni A D. I..Ivanovskiy, Academy of Hedlical Sciences USSR,:a,ad the Institute of Epidemiology and Microbiology imeni N. F. Gamaleya, Moscow,. "Detection of Oncornaviruses in Continuous.Tissue cultures" Moscow, Voprosy Virusologii, No 4, 1973, pp 411-414 Abstract: Studies were conducted on a number of human and animal continuous tissue cultures maintained in medium 199 containing 10% bovine serum to determine oncornaviruses. Formation of oncornaviruseu in the tissue cultures were followed by the appearance.of,virtal particles in the culture fluid labeled with H3-uridine, suseeptibility,of their synthesis to low actino- mycin D concentrations, appearance of these particles,follm,7ing inhibition of nuclear material synthesis by bromodeoxyuridine or mit=ycin, presence of reverse transcriptase in these particles, presence'of 60-70.S RNA in these particles, and electrcin microscopy. Of the 26 human lines investigated 14 contained type B oncornavirus, and 4 lines type C virus. Eight of the 1/2 MUNI;A 141'&6 9W M-1 Molecular Biploo, USSR UDC 578.6 YRR9HQY_ E, I., BYKOVSKIY, A. F., URYVAYEV, L. V., S,OKOLOVA, T. M., and ZHDANOV, 17. M., Member Academy of Medical Sciences USSR, Institute of Virology imeni D. I. Ivanovskiy,-Academy.of.Medical Sciences USSR, Moscw "The Morphology of Hybrid Ribonucleoprotein Complexes (Pseudoviruses)" Moscow, Dc,klady Akademii Nauk SSSR, Vol 210, No 5, 1973, pp 1206-1207 Abstract: It was established in earliermork by Yershov et al (DAN SSSR, Vol 189, No 4, 882, 1969) that addition of the infectioALs RNA of the v-irus of Venezuelan equine encephalomyelitis to the fraction S 105 of the hyalo- plasm of d-iick embryo fibroblasts results in the formation of hybrid ribo- nucleoprot,ain (RNP) complexes (pseudoviruses):that consist of the virus RNA and cell p:coteins and differ from the virion RNP in regard to their sedi- mentation distribution and floating density. ;They are insensitive to the action of antivirus antibodies, but at the same time exhibit infectious activity. In the work reported at present, the morphology of the pseudo- viruses in question was studied by electron microscopy. It was established that.the optimum ratio for the formation of the RUP complexes was 400 gamma virus RNA to 1.6 mg protein. On purification of the RNP~complexes (pseudo- viruses) by centrifuging in a 10-30% density gradient of sucrose dissolved 1/2 FAIN USSR YERSHOV, F. I., et al., Doklady Akademii Nauk SSSR, Vol 210, No 5, 1973, pp 1206-1207 in an iisotanic phosphate buffer (0.1 M NaCl, 0.01 Kphosphate buffer, pH 7.2) the fraction corresponding to the -peak of RNP:co:nplexes (80 S) was col:.ected and studied by means of an electron microscope. Centrifuging in a C�(Il gradient was also carried out. Threads with a diameter of 25-30.A and bundles of these threads were observed. The hybrid pseudovirus complexes resembled the-virus RNP and differed from Uformophers in.size R_ uDo 615-281-8:576-858-09B-396-332 NOVOKhATISKIY, A. S., avid -YEMOVL,.Z&J_., Institute of Virology imeni D. I. IvEmovskiv, Academy ofNedical Sciences, USSR "Inhibition of the Multiplication of RNA-Contaizivg Viruses in a Tissue Culture With Combined Use of an Inducer of Interferon Productio-._i and a Ribonuclease" Moscov, Antibiotiki) No 7, 1973) V01 18, pp 629-633 Abstract: The fact that co--plexeE; of pol, ynucleotides can stin~Llate the rroduc- tion of iiiterferon leads to consideratiori of the possible therapeutic and pro- phylactic use of such preparations. Further,*it has recently been established that nucleases have a definite antiviral effect. In the current investi~;ation, the combined used of ribanuclease (an active-inhibitor.of the reproduction of RNA-conta:ininra virises) and polyIC (a complex, of synthetdc pol~nucleotides of polyinosinic. and polycytidylic acids, one of the Yrost active and least toxic of the synthctic interferono-ens) was tested with primary trypsinized cultures of chick eirbryo fibroblasts. Previous investif;atian has G~toved Oat complexes located or, the outer part of cell surfaces are senaitive to the action of pancreatic ribonuclease. Thun it is -possible ~ that the antivirus effect of polYIC 7mrifests itself as the preparation -passes from the outer cell surface Into the interior of the cell. The initial ribonuclease-sensitive phase was 1/2 USSR NCVOKI,-,kT,)KIY A. S., and YERShOV., F. I.,,.Antibiotiki., Ito 7, 1973, Vol PP .629-633 determined; it varies depending on type of cell, species of virus, and other ftctors.~ Successful combination of.the nuclease and the interferono~ren is possible only upon conclusion of this phase.~ Lhe coffbined application is based on the principle that the antiviral state developed by the use of the polyIC is na~.ntained when the preparation is not actually presen *t,(at least on the cell surface). It is concluded that a combination'of'the official pancreatic ribo- nualease and an interferonogen is possible,:in:princip1e,, and further investi- gation is,required for.the extent qf:anim~l.application' 2/2 14 3019 -117 N. RUF 010 M i"', - P. ~-' Abstract: Chick embryo fibroblast cultui,es were tested for viral in'fectious- ness and hemagglutinating activity and for interferon 24 hours after infect-ior, by-5-10 pLaque-form-ing units/cell of Venemalan equine encepbalomyclitis vii-us. Mere was approxi~nmtely linear direct correlation ibetwe-~!n the dose of pan- creatic r1bonuclease added to the culture and the suppression of infectiou3- ness, hems.gglut-inating activity, and interfer--n production, with si,~nificant suppressicn. occurring at doses as.low as 0-25,mg/ml. Statistical treatme-nt of e>werimental O~ita indicated that. the degree of Suppardssion of all three indexes can be determined on the ba,~is. of ilnfoivation an J-UE;t one of the indexes. Me results support the suggestion that~RITA-a:te inhibits viral activity and interferon production by suppressing celluhar protein synthesis. It is concluded that T)ancreatic RITA-ase is an effective viruss~coutrollinc' comi- Anistered together i-iith irrterf pron. potuid, esproweially when adn 46 USSR UDC 576*.858-25-098-396-332 AGABALYAIT, A. S. IURYVAYEV, L. V..1 and Y2.RSHOV, F. 1.,~ Institute of ViroloCy Imeni D. I Ivanovskiy, Academy of YjedPraISIJHeF8d9I;-U!ISR, ~Ioscow "Charact,:!ristics of Viral RIM, of Venezuelan Equine Encephalomyelitis Virus" Moscow, Yoprosy Virusologii, No 4, Jul/Aug 72, pp, 4~0494 Abstract: The physicochemical properties of viral MIA isolated from 'Venezuelan equine encephalomyelitis (VED) virus were studied in comparison to those of other group A arboviruses. R14A was labeled with O-uridine and studied. spectro- photometrically. The FNA formed a single peak in a sucrose gradient with a sedimentation constant of 35-40S. This peak was sensitive to RITA-asf-, and its maximum i rife ctivity coincided with the maximum of radioactivity. Electro- phoresis Df the MiA in 3-5% agarose-polycarylamide gel indicated that iL was homogenco.is and pure, and enabled determination of its molecular veitzht: 4-:0- 10b-4-3-1)p daltons. ViThen fractionated~in a cesium sulfate density gradient, the RUA si%.ttled in a single zone with density.1.55 FA/qm3. These findirlIrS support previously published evidence that viral IU4A is heavier than tied been supposed. Differences in other properties between data on VF2 virus 1W given NA of other A arbovin-ases are ninor a here and previously Rablizhed data on IRI nd can be attributed to variations in experimental procedures. T~aus it is con- eluded flu,.t VEE virus RINA is identical in physicocheinicitl properties to other A arbovirLtses. USSR UDC 576-858-095-5049-3) 'YERSIT.O-V.,-F,,..., I., Professor, Doctor of Medical Sciences: (Reviewer) 11,1,ita6enez -fi~~sov Chelovelka i Zhi-votnyIZh Olutagenasis of' Hunianiand An--.Tmal Viruses), by Zaeukhina, G. D., Moscow, Me-ditaina, 1911~ 180 p-p MOSCOW, Voprosy Virusologii, No 4, JulAu'g 72, P 503 Abstract: This monograph analyzes factors controling inutagenesis in viruses. Part 1 deals with the use of plaque formation as a genetic trait by which to describe and differentiate viruses. Part-2 describes the principle differences between hereditary (mutational) and nonhereditary variability in viruses in com- parison to bacteriopha-les. Part 3 deals with spontaneous mutn6enesis in. natural and experimental conditions. Individual ganatic tralts are discuFsed, and methods for obtaining altered. variants experirant -ally are described. Part 4 providen information on inrlL~cing eXDC rind nt-qlly by varying environmental conditions. Dita on bacteriai phages, ai-4 acti-nomycates are added in classff,,in.g chemical rmAtagenr. und describin-Y their pro-perties. Parto 5 describcs possible syc;tems for repairinj~ gene-tic daiatGe on, the basis of data on both microorganisms and cells of higher animals, and the author's own experimenial findings on viruses.. The monograph contains h bilbliogr~,phic index. Vi 33 -777- 7 USSR UDC 615-37:576.858-095-3831-015 TAZULAKHOVA E. B., and YEFSHOV F. I., Institute of Virology imeni D. I. Ivan- ovskiy, Academy of R'ad:f6af 8c1eF6es.-1)SSR.,, Mon c ow "Some Aspects of Interferon Activity" Moscvw, Antibiotiki, Vol 17, 170 10,. 1972, pp 940-945 Rostract: Resistance to Venezuelan equine encephalo.,T,-elitis virus developed by chick embryo fibroblasts in response to act-ninistration of homolosous int,~rferon depends on the time and dose.of the virus and:,interferon added. On the average, resistance:begins to develop 1-2 hrs after.administration of interferon, reaches a maximum in 5-6 hrs, and remains constant as long as interfe'ron is present in the medixin in ample concentration. The best results~are achieved by adding interferon-prior to inoculation. Infc-ction i!.; 'not prcvonted :Lf int(~-rjfcron iz administered 2-" hr.- after inoculation. Reirov,%l of' interferon from thc; n,~edium. is followed by a fall in resistance in 6-9 hro, relfrardless of the inoculation and.thi~. initial concentration of, interferon. Mus -period coincides %,ith dose the.functimial period of the antiviraLproteinp 'USSR Ux 576.858 -096-396.3-~9.095 -38 URYVAMI V., SOKOLOVA, T. M., YE13SHOV F. I., and ZHDANICIT, V. M., Institute of ViroloCy -imeni D. I Ivanov-.V cademy of 1-It-die'al Sciences UfM, MOSCM7 "A Study of the Phenomenon of Complex-ing Blet-,reen Viral XTA and Cell Proteins" Mo~cow, Voprosy VTO 61 11011r/alc 72) pp 67o-676 fibstmact: Physicocheraical Tiro-De-fties of chick emb--,~ro fibroblast protcins plexing with Venezuelan equine encephalo;-!~/elitis vi'mas 11211A verc stuclic;C1. cc)-.,- plexin- ao-tivity bc.-twecn nrotf-~n, isolatut:L in.-,, UUJE-aellul ose cr~'Lv-e~-!n at -p!' 6.8 0, apA not sedixiontin,,, 1,13011 105, 000 r,' certrif illy,-ati6n, Mlcl~ 'd ENP, judVri by the degree to which MA -,ras arrested by a Y.*A1:Wuovk1 fLLJ-,(-~y. Tlij!-Oc; classer, o-.' proteins (320', 95, and 6-4.5s) with diffearing compl~!~xinL, act-1.vity 0 ~, r!,-- d-* w were sepam-ated on v nucro,,e Uradiont. Ionic strtmr~th of ir I has mn efTect, on cummlexin,,! activity: Incre,-xiiiL, t1u.- cancv-,nt7,.,-,tia1-, 0.01-0.114 to Qv5-11,-i coil s idcrabi_v roduces somtion of v-i---a-I JUIA. it -was ,.!so shown that. RMA, Gox-ptioli cb:~crease:3 as the protein concen',-,raticm is decreasc-,~. -U~-: -n-o"e-n wei;,~,41t 1-atio frcn 1:6 to. 1:1-1 C 0 C.- U a drop in ribo-nue-leorratein --c6in-~!ntatjori constt-tnt fro,:" 85" t,,, 57S. heavier viral RMP. coincidc!rt th~,-- peal, of maxiiztzi U suggra-GQ,ad Uiat- hit~~h ionic -,"aJ--nr-th ca,11-e-1, i;hral RIM to fr,--,n compact maits 7. 7; M zS R URYVAYEV. L. V.) et a!., Voprosy Virusologii, 'No 6, Ti'ov/Dec 72, pp 670-676 cannot react readily vrith protein. Though the biological significance of REA: J protein co=lexing remains. unclear, the fact that such ccm-lexes arise in iso- tonic meedl.a sur LI cells. The rcla- ,~gest that such structims: exist in infecte tionship between the i-ieight increase of viral MIA and the quamtity of prote-ill available suggests that when protein is lou in quantity1t distributes itself uniformly,apong all PJ-TA moleowles,, IA - sedimentatiob rate does not incre and: RI P-se noticeably., 2/2 USSR UDC 576.858.25.0.8.396.332 AGABALYAN, A. S., IEN'SHIKH, L. K., and Institute of Virology imeni D. 1~ Ivanovskiy, Academy of Medical Sciences Min "Factors That Influence the Level of Infectiousness of Venezuelan Equine Encephalomyelitis Virus RNA" Ifoscow, Aroprosy Virusologii, No 5, 1971, pp 527-532 Abstract; The titers of infectious NIEE virus RNA are highest after the calls are. treated with 1 M NaCl solution. for 15 Pin at room temperature. DEAE dex- tran (2 to 3 mg/vil) m-Ld protamine sulfate (0. 3 'to 0. 6mg/ml) added to the agar overlay increase the number and size, -of.the plaques formed by RNA and intensify its infectiousness. The RNA titers are highest when the nuclei acid is adsorbed on the cells for 2 to 5 min -at room temperature and at 370C.- Prolonging the adsorption time markedly lmjers the titers of in- fectiousnctss. Treatment with-RNAase completely neutralizes the infectious- ness of RDIA, whereas treatment of the original virus wiffi the same enzy-me 'has little, or no effect ia this respect. Immune serina,against VEE virus has no affect on plaque formation caused by RNA prop arat ions, but it greatly reduces the infectious titers of the original'viruo, Infectious RNA is 1/2 USSR UDC 576.858,25.097.2 URYVAYEV, L. V., CHEPULTS, G.-K. DEPKACH, Yu. S.t_7,11DANIOV, and F-I. . Institute of Virology Imeni D. I. Iva7novskiy, Acadcmy of Medical Sc:Lcllcp-s TJ~~Sp, "Protein COnDOnCnt3 and AnLinens of Venezt.,Olan Equine Encephalomyclitis Virus" Mosca,,, Voprosy Virusologii, No 5, 1971, pp 586-589 Abs tract; T"he pi:otc-,in comm;iLiDzi oil highly purified Venctzuclan equine VJrLt,-; Wzl, studif-ed by electrophore-1-is in poIyacrvL~..,,IICI(I gel 4-111"1 by O'cub1ct. (15-if"Ision ja zq-inr. rjotlh rcw:aled the prcseace in the virus T)artic.IC4, of Llo-e~: vixu8-spccific pro LCA-.113 With antic;enic properties. USSR VDC 576.858 GAYTSIMOKE, V. S., ISHOV F I KISELEV, 0. 1., MEN'SHIIC H, L. K., ZAYTSEVA, 0. V., UIUVAYEV, L. V_ tDt'OV'.*V. M., Member of the,Academy of Medical Sciences USSR, and NEYF-*M, S., A., Institute of Virology imeni D. I. Ivanovskiy, Academy of Medical SciencesIUSSR, Mdscow,,~,and Institute of Experimental Medicine, Academy of:Medical Sciences USSR, Leningrad IlReconstrUCtion of the Autonomous Genetic and Protein-Synthesizing System from Virus RNA and Isolated Mitochondria" Moscmir, Dcklady Akademii Nauk SSSR, Vol.201, No 1, 1971, pp 220-223 Abstract: In ex eriments performed on isolated mitochondria of rat liver incubated with H -RNA obtained from purified.Venezuelan equine encephalo- myelitis virus, it was demonstrated that,the virus RNA'tenters the mitochondria and is incorporated into their autonamousisystem of protein synthesis, for which the mitochondria supply the necessary energy. Transcription of the mitochondrial.DNA is inhibiced, the virus XNA is replicated,, and thus virus proteins are synthesized, 13 WIT Ail 15 5, ~ '; RIF W1111 - WON Hg I T 7~~1 3 LLq %q UDO 576.858.098.396-33-P-083.1 KISEELEV, 0. 1. 1/01PSHIM, L. K., ZAITSEVA W=TWOKI, V. S. YEERSHO 0- Y YHYVAT-7-1, LO-7. , Z14T)ANOV, V. M, , and NEYFAY."H, A, Institute of E#erinent.L1 1-leddclne, USSR Academy of Hedical Sciences, LeninEgrad, institute of'-Vir-ology imeni D. 1. Ivanovskiyj USSR'Academy of Kledical Sciences, E scow .0 "Replication of Infectious Viral R11A.in Isolated 11ttochondx1a. Report It Pdnetration- of Vira-1 Ma Into Mitochand4a and Its. M6~t on: Utochondrial M6d=wi'VoPro5Y virusologii, Ila 3 1,hy/Jun 71, pp 269-2?3 Abstracti Isolated rat liver mitochondria were incubated in a medium pro- n. oting oxiditive pbo3phorjlation and protein and 1U.11A biozynthesis. O-R:,~A ae_Wnezuelan equine encephalitis -virus was added. It vas found that after ihculationt approximately 72;~ of the introduced radlo-a~tivity was in the iuiria. - It, was concluded that the emerg mitocho, ence~ of 10-MA, ~of the cirus, in the taitochondria is not due to adsorption of ETIA an the',surface of these structures; instead, the cell fluid and actinomycin D stiraulated MU -,~.ene- traiion-. . The air,-ribution of v' -raI MA In-mitochandria-1 sulfriactions was studied': ApI)rQximately 64,1S of tho labeled Mt wa3 four.,L in Uhe internal membrane and. natrix fraction. Inhibition' of:2111A synthesis of initocbondrial pj~otein uas observed. The ftactionof actinomycin-resl8tant protein synthesis ............ -.- 576.858-098-396-33 .083.1 USSR UDG 2 YERSHOV, F. 1.j GAYS001a, V. S., KISELEVy 0. Xss ZAYTSEVAr Ov V. t MENSHIKH, V, L. V.j 1%WAKHr S. A., and ZBDANOV, V. 21-1 Institute of V Cal losco irology imeni D. 1. Ivanovskiyj WSR Academy of Yjadi Sciences, 1-1 W Institute of Experimental Medicine, USSR Academr of Med#al Sciences,. Leningrad "Re cation of Infectious Viral RNA In Isolated lllitochondxia. Report Ut pli Replication of Viral RNA in Utorabondria and Oharmater.1stics of the Final Product!' Hoscowl Vaprosy Virusologiis NO 31 May/Jun -11, pp 274-280 Abstract i It was of intexest-to establish whether isolated m1tochondria. could rep]-tcate virrus RNA, that is whether ~".I~acterial" ribosomes could synthesize the functionally active RHA pol~merase-j- and'whether;the final product of virus-specific synthesis has 5nfectious properties. H3-RIIA isolated from purified Venezuelan equine enceplxa-ftls~:virus ira--ir used to study the func- tion of v.4.rus RNA emerging in mitochondria., Contact. between mitochondria aiid RM4 was 31) minutes at OOC. After this, the r1tochondil.a. were incubated under aerobic conditions for 2 hours at 37 0C. After te-xvdnation of the incubation period# RNA was sepaxatecl by the phenol deproteinizing,xiethod and analyzed in a sucrose density gradient (5-3Viof), Fealre were found In the 403 and 26-205 region. The 403 area corresponds to JUIA-'ase- and the 26,-20S axea to ribonu- ;7* 7 ~7' 7' USSR!, YERSHOV, F. I., et al.~ Vopresy Virusologiit No 3t May/Jun 71, pp 274-280 clease-resistant materialf the re-plicative fo--m of Viral RNA. The data obtained indicate that the predoainant portion of viral RIU app-saxing in mitochondria does not participate in the replication process.and its dehydration product-s show up in tho top zone of the -gradlent. : No radioactivo products of mito- chondrial RIIA translation were detected, which can be e3cplained by the effective concentration of actinomycin D. As the nouly:synthesiud R14A fo=s complexes with'.proteins infectious activityIncreasess:: The complexes formed have subce3.lu3,sx structures and are sepaxated from,infected'dellso 2/2 20, 7:T. Micro'bioiogy USSR NOVOKHATSKIY,.A. S., and I., Institute of Wrology imeni D. 1. Ivanovskly, Academy of Medical Sclences'll SSR, Moscow "Thermal Inactivation of Viruses. Report.1V Factors Determining the -Dynamics and Rate of the Process of Inactivation of Venezuelan Equine Encephalomyelitis (VEE) Virus) Moscow, Voprosy Virusologii, No 2, Marc/Apr 71, pp 143-150 Abstract: The effect of a number of biological, physical and chemical fac- tors on the course of the process of loss of-infectioun activity at various temperatures was studied ou a model of Venezuelan equine encephalomyeli -Lis (VEE) v.,,rus. Virus populations obtained onfleLaond PIASHA culls were less resistant to heatin.- than virus populations obtained an trypsinized chick. embryos and US cultures. Ultracentrifugation decreased the theimostability of VEE -virus and increased its sensitivity to the thermostabilizing effect of 12.5% magnesium sulfate. Unrering the p1of the virus-containing sus- pension from 9.0 to 7.0 somewhat delayed thermal.inactivation of VEE virus according to the nucleic type, and wider pH shifts sharply accelerated dying off of the virus. In all cases changes in the duration and d~,mamics of the 1/2 loll USSR UDC 576.858.25.098.396.332.576.858.25.097.21 URYVAYEV, L. V., and ZHDANOV, V. M., Institute of Virology imeni D. 'I.,'.1vaaovskiy, Academy of I'lledical'Sciances USSR, Moscow "Synthesis of Infectious Ribunucleoprotein:of Arbcviruses in Subcellular Struc- tures" Moscow, Voprosy Virusologii, No 3, May/Jun 70,1-pp 322-330 Abstract: A mitochondrial-microsomal (~Df) fraction isolated from chick fibro- blasrs infected with Venezuelan equine encephalomyelitis-virus (VEE) and incubatg-d in medium 199 ensures extracellular:synthesislof virus-specific RNA and protein and the formation of ribonucleoproteimcomplexes (11NP). These complexas possess infectious activity, which increases W-100-fold in 3-4 hours of incubation. The RNP complexes ciontain the infectious RVA, which may be-associated both with the virus-specific and one cenaar proteins. The main part of the infectious RNA is foxmed~extracallularly and not because of complet,lon of the templates derived from zells together with the MM fraction. 1/1 ~7 7= 'USSR UDC 576.858.25.095.383.098 ZRDANOV, V. M., YE%SH and,URYVAYEV, L. V Institute of Virology imeni, D. 1. 1vanOvs7TY, ~AcademY of efedical Sciences USSR:; Moscow "Virus Ltke Particles Formed in vivo and i~ 'vitro" Moscow, Voprosy Virusclogii, No 5, Sep/Oct 70,: pp 537-54 3 Abstract: It was shown that ribonucleoprotein compleyes' capable of producing infections and typical plaques in agar were formed in the mitochondrial frac- tion. isolated from cells infected with Venezuelan equine encephalomyelitis (VEE) virus during incubation in proper mediai . Sedimentation. constants of these complexes in a linear sucrose gradient.ranged fropi BOS and 160S. Their buoyant density in Ca gradient varied from 1.30 to 1.42'g- VCM3. Virus-like particle!s ("pseudovi ruses") with similar Icharacteristics were found after addition of the Infectious RNA of VEE virus to homogenate of uninfected cells. These pa-zticles were partially resistant to r1bonuclease and,could not be neutral,"-zed by virus-specific. sera. It is. proposed that the formation of virus-ILke particles in vivo and in vitro is,based on sinze com?lexing between viral 'KA& and cell proteins, in u hich case it is possible that formation of Ynfbxmosomz-typa structures may occur, USSR- UDC 576.858.25 URYVAYEV, L. V., ZHDANOV, V. M., YERSHOV F I., CHEPNETSOV, Yu. V., and BUKOVSKIY, A. F., Institute of ViPUI~Uk lmian-JD. I. Ivanovskiy, Academy of Medical Sciences its edimentation Characteristics of Venezuelan Equine Encephalomyelitis (VEE) Virus" Moscow, Voprosy Virusologii, No 3, May/Jun 70, pp 310-336 Abstract: VEE virus was cultured in chick embryo fibroblasts, concentrated and purified. The optimum method for obtaining biologically.active virus components consisted of destroying the virus with ether and Tween. Purified VEE virus sedimented at about 380 S in sucrose gradlents,.the.nuclei at about 160 S. Cen- trifugation in CsCl gradients showee. that VEE infectious material bands in two main posi%ions: most of the virus-banded at 1.25 g/ml, and a i3maller amount at .1.42 g/ml, The main peak of hemagglutinins,was detbctedlat a buoyant density of 1.25 g,'ml. 13 USSR UDC 576.858.25,083.3 NOVO.-MATSKIY, A. S. , and Y Imsticute 'of Virology imeni D. 1. Ivanovskiy, Academy of Xedical Sciences USSR,, Moscow 'InierI]iDD Dj) 1))i~ '~rDbuction ol T&27ezve2.w 2~qvlne 2z2cep~z,?2oazy4e2jt-Is virus" Mos.cow,Yoprosy Virusologii, No 3,.May/June 70, pp 265-269 Abstract: V,-tezuelan equine encep1halomyelitis virus wa4q cultured on chick embryo fibroblasts in monolayer stationary culture, in uu~;pcn*;Lan, and in roller culture, with sing-le infection or multiple infection. The greatest virus yields were obtained in roller cultur"i, Thfi~ srnallesC y~olds were ob- taiaed from multiply infected cultures. This was aLtributed to the presence ef. interferon. USSR UDC 576.311.1 URMYEV, L. V., DEMO, YU. S., Z HDAN. 011 V. 11. , ar4 YERSHOV. F. I. Institute of Vi=logy imeni, D. I. Ivanoyskiy, "Structural Proteins of Venezuelan Equine Encepbalomyelitiz Virus" Moscowp Biokhirdya, No ll 1971, py 92-96 Abstracti Polyae-~Iazida gel electrophoresis xevealvd that Ughly pwrifiez' V~ vinis contains -hxe* --a-A.Ln proteins, , The ribonucloo-protain fraction isolat&- by centrifuging vi--zs destxoyed by tureen and in a parformcd cw~itm cb10=14de dezaty p:aacnIt (1,43 r,/c~3) contaired a pl-ot-cin with a molecul= veight ofP 59POOO to 61#000, Tte nore nobile terii; p,;Iutinin haA a P-oleaul-ar weiaht at 14.000 ta 18.060- Thn frneittnq %thieth -rpv 1/2 016 UNCLASSLFI,ED PROCESSM OArE--30OCT70 TITLE--,THE FACTORS, DETERMINING THE REPRODUCTION OFTHE 'VIRUS REPORT I THE IFLUENCE or- THE !NFECTION MULTIPLICITY'ON THE REPRODUCTION OF AUTHOR-tO2)-NOVOKHATSKIY, A.S.& YERSHOVv: F:.J. _.-CCUNTAY (IF ljN*0--USSR --SOURCE--VOPRGSY VIRUSCLOG119 19T0, NR 3~IPP'265-269,1- _':~OATE PUBL ISHED -70 BJECTLAREAS-131OLOGICAL AND MEDILAL SCIENCES .'~.TOPIC TAGS-VENEZUELAN EQUINE ENCEPHALITIS VIRUS, INTERFERON, CULTURE METHOD ~C-CNTRCL MARKING--NO RESTRICTIUNS -DOCUMENT CLASS--UNCLASSIFIED STEP NO--UR/04 'PROXY REEL/fRAML--2000/1746 .021 70M-0/003/026 5/02 W) NO---AP0125364 UNG L AS 1 f! I E D Ann- NMI gmal W-REWWRINTM LaUMM m 016 UNCLASSIFIED PROtESSING DArE--30OCf7O IC P. CACCESSIGIN NO--AP0125364 !_AMTRACT/.E`XTRAC.T--(U) GP-0- ABSTRACT. IN THE PRESENT PAPER THE IiNFLUENCE OF THE IfiFFEkE;qT CONDITION 01: T HE CULT I VAT IOIN AN 1) Y.~FE MULTIPLICITY OF THE INFECTION ON THE REPORDUCTION OF THE- VENEZUELAN Et~,UINE ENCEPHALOMYELIT.IS VIRUS WERE INVESTIGATED THE VARIOUS TYPES OF CULTURES 6ERE USED: PONOLAYER STATIONAL LLTURESr RQLLI~R.CULTURES AND SUSPENSICN OF THE CELLS. THE HIGHEST VIRUS~ YIELD 'WAS bliTAINED IN THE ~1;;-.-RCLLER CULTURES.' IT WAS SHOWN THAT IF THE~LES OF THE S MULriFILICITY INFECTION HAVE BEEN USED, THEN THE VIRUS'-YEALD WAS. Iff GH Ea. THE -IMECHANISM DETERMINING THIS FENOPIEN AND THE POSSIELE. KOLE OF THE 10 NEWLY N .::INOCULATED AN FORMED INTERFERr AREDISCUSSEL) FACILITY: -:j,_ANSTITUT,VIRUSOL0GII 114ENI 1). 1., IVANOVSKOGO AMN S'W, MOSKVA. UNCLASSIFIED' PRO(ESSING DATE--30OCt7O ll;~ 013 41TL IE-SEDIMENTATION CHARACTERISTICS:OF VENEZUELAN EQUINE :.-.,~--~ENCEPHALOPIYELITIS VIRUS -U- AUTHOR-(Q5_J-URY.VAYEVp L.V.9 ZHDANOVI V.M.#:,YERSHOV, F.I.9 CHERNETSOVs V.v-~SYKOVSKIY, ASF. t.41 UNTW GF I NFO--USSR, ' s E-VOPROSY VIRLSOLOGII, 1970, NR 3s PP 330-336 boRc 0 TE PUBLISHED 7 0 -~-SUBJECT AREAS-BicLOGICAL AND MEDICAL SCIENCES CTAGS' VENEZUELAN EQUINE ENCEPHALITIS VIRUS. TISSUE CULTURE* p It D,.IMENTATION CCUTROL MARKING-NO RESTRICTIONS I)CCUMEN'T CLASS-UNCLASSIFIED -PROXY REEL/FRA14E--2000/1836 STEP NO--UR/0402/701000/003/0330/0336 CIRCIAGILESSIEN NC--AP0125447 UNCLASSIFIED 2/2 -013 UNCLASSIFIE-0: PROLESSIN-. DATE--30OCT70 [CIRC. ACCESSIONNO-AP0125447 ~~%BSTRACT/EXTRACT-(U) GP-0- ABSTRACT. THE VEE VIRUS WAS PROPAGATED IN CHICK EMBRYO CELLS, CONCENTRATED AND PURIFIED. THE OP'l*IMAL METHOD FOR OBTAINING 81"'ILOGICALLY ACTIVE VIRUS COMPON8NTS CONSISTED IN DEGRADATION ~--OF THE VIRUS WITH ETHEA TWEEN. THE PURIFIEDVEE VIRUS SEDIMENTED AT ABOUT 380 S, ]IN SUCROSE GRADIENTS,,THE- NUCLE-OID AT A13OUT.160 S. CENTRIFUGATIGN IN CSCL GRADIENTS SHOWED THE VEE INFECTIOUS MATERIAL 1'O BAND IN T~iG MAIN POSITION: MUST OF THE. VIRUS SANDED AT 1.25 G-ML, AND A ~SMALLER AMOUNr AT 1.42 G-ML- THE MAIN PEAK OF HEM.A*GGLUTININS WAS DETECTED AT It BUOYANT DENSITY OF 1.25 G-ML. THE SITE [IF VIRUS AND ITS C. OM P C' BIOLUG SNE N 1. SW-AS DETERMINED BY RADIOLOGICAL AND [CAL 'rESTS. FAC I L I T Y-INSTITUT VIRUSOLOGII IMENI D.: I.AVANKOG0:01N SSR, MOSKVA. --Ulf-- -A f:-r-P n UNCLASS" IFIED;' PROCESS [~G OATE--30OCT70 -:.TJTLE--SYNTHES IS OFINFECTIGUS RIBONUCLEOPRUT~IN OF ARBOV[p.US IN ELLULAR STRUCTURES -U- THQR-013)~-YERSHO URYVAYE-V,.L.V.,, ZHGANOVo V*'M. ttuh,TRY OF INFrj--t;SSR 7--SOURCE-VOPROSY VIRUSOLCGLIs L970, NR 3, PP 322-330 ,0ATE :PUBL ISHE-D----70 ,-tUBJEC -310LrGy! 'EDICAL -CIENCES CAL A.iD e -!LTURF V 1 F, U SR IN A TCPIC TAGS-ARBOVIRUS, VENEZUELAN EQUIN EPICEPHALIT,15 MED "Um 'C CN TROI MARK 'XG--N'C RE5TRICTIUNS .00.C.UMENT CLASS-UNCLASSIFIED "PROXY'REEL/FRAME-20001184r7 STEP NO-UR/0402170/00010011/03'1>210330 ~CIRC ACCESSHN NG--AP0125458 UNCLASSIFIED 016 UNCLASSIFIED PROCESSING DATE--30OCT70 ACCESSIGN NG--AP0125458 ,4BSTRACT/EXTRACT-(U) GP-0- ABSTRACT, MIT.DCHONDRIAL MICROSOMAL 111,M) ION ISOLATED FROM CHICK FIBROBLASrS 4NIFEcrED 1-11TH VEN~:LUELAN EQUINE -,ENCEPHAL OMYELITIS VIRUS (VEE) ANO INCUBATEDIN MEDIUA 199 INSURES -~.EXTRACELLULAR- SYNTHESIS OF VIRUS SPECIFIGRNA AND PROTEINS AND FopullATION OF Rlt3CNUCLEOPRITEIN (RNP I COMPLEXES. .~ THESE COMPLEXES POSSESS :114FECTIOU-S ACTIVITY WHICH INCREASES 80-1,00 FOLD IN 3-4 HOURS OF 111CUBATION. THE RNP COMPLEXES CONTAIN INFECTIOUS RNA WHICH MAY BE ~-ASSGCIATED BOTH WITH VIRUSSPECIFIC AP40 CELLU~-AR PROTEINS. THE MA!lq PART THEJNFECTIOUS RNA IS FORMED EXTRACELLULARLY A NO N 0 T AT THE EXPENSE OF TEMPLATES DERIVED FROM THE, CR-LS TOGETHER WITH MM Fk4C-TION. FACLLITY: INSTITUT VIRUSOLOG111 IMENI 6. 1. I VA IN OV S K 0 G 0AMN SSSR; MOSKVA. UNCLASSIFIED fiE 1ZSR UDC: 576.858 EV, L.V /a V.M.j1 YERS_ URYVAY na ZEDADTOVJ1 Academician, Academy of mM~L'sciences USSR institute of Virology imeni 1). 1. lvanoysliy, Academy of Medical Sciences USSR "Synthesis of Arbovirus MIA and Proteins in Subeellular:Structures" Moscow, Dcklady Akademii Nauk, Vol 190, No 2,1197o, pp 458-46o Abstract: A fraction containing the subeellular structures (8S-15) was ex- tracted from chick fibroblasts infected vith Venezuelan equine encephalomyelitis virus and from intact cells. The fractionwas diluted (1:10)~with medium 199, and incubated for 1-2 hours at 37C)C,:after which H3-uridine and a C14- amino acid milyture were added. After rapid chilling, the SS-15 fraction and accompanying products were centrifuged (1500 g),and analvzod in a sucrcse density gradient. Supernatants of ihe infected cells contained a product with.a sedimertation constant of 4 OS, and lighter, slcmer settling products in the form of MIA and polypeptides, whereas superratantr, of the noninfected cells contained only the lighter products. After gradient centrifugation of the SS-15 fractions isolated from infected and noninfected cells, nucleic and protein tags were found in the form of two peaks one,of which was linked to the'structures, while the other apeared in the lighter part of the gradient. It wan concluded that subeellular otructures consisting ot' cytoplamatic mciabranes witli ribonoomes -and mitochondi-in are a milve-snierit'. mo(lel for Otudyin13 virus-induced synthesis. ,r --gimalm-mair ?,3 SIR UDC 3 76~.,:), r s, C- r, a, 'D vs cz 0 Lx tL ior, c jr,-r-- Zl _OW, Volt r Us o o "To 1 Mum c On,-, -i t io r1 s ~_Or t h of "P ~,' - __ and -L- In f chick e-,or-o cal- 0- f c u i V a ti o 3 ta t oaa z c-2 SU'A~Cll S 2. 011,13 t~ rid, e r L. n a c. leve! d --a t e ,7, 1' n e dri, a _7 ny There S -L r -~ ~ a :: i, o bety.,,ean Z~ L a a o n ous a ti " IIIC7,:mfaf'-, -"IL "I' '~-ivitvl ILILI, 't:L~, ~~ aC erl-'eron - : , ) ~ 0 0 L 't, ormed when x-o-Lier cu-, al 7:, Pc~_enacdi the Fcar CZ, _rU L "Iters r ea c bu- 370 C tho-Y d. 1/2 s s R, aL.? y rjV p 34-37 P s th n Act', t r a c a s e i1 Dr . stead oduct- v - -- " . rus ~Llk. ~ er;.'~Accs ind-i'vidual di'- ' - an ir 4 1%- n CS: f V* US t:e ,La S:1.1 CLU.C.Ln e^L I leity o Cap, L lnc ~PRbd8SSING DATE-11SEP70 UNCLASSIFTiED;i -VIRUS INDUCED SYNTHESES ON PREFORMED SUBCELLULAR CULTURES -U- ~-":AUTHOR-ZHDAI~OVI V.M.t YERSHOVI L-V. NOVr]KHATSKIY, A.S. Fef.t URYAYEV OUNTRY 13F-tNFG--USSR --VOPROSY VIRUSOLOGIT, 1970, NR 1, PP 3 46 8r ~,._OATE PUBLISHED ------- 70 AREAS-810LOGIrAL AND MEDICAL SCIENCES ,c:`Tb0IC.TAGS -PROTEIN SYNTHESISt TISSUE CULTURE, EASTEqN,EQUINc- EN, CEPHALITIS VIRUS, VENEZUELAN EQUINE ENCEPHALITI.S.-VIRUS COMTROL RESTRICTION5 ~"-:_:PCCURENT CLASS-UNCLASSIFIED _~-_PROXY RECEL/FRALIAE-1987/0053 STEP 140--UR/0402/70/000/051/00"R/0046 CIRC ACCESSION NO--AP0103733 PROt:rS S ING DATE-- I I SF97 0 .212 013 UNC L A FIED n RC ACCESSI,9-N NO--AP0103733 --(U) GP-0- ABSTRACT, IN THE: STUDYv~ SYNTHESIS OF ~NA AND ,ABSTRACT/.EXTRACT P.R.OTEIN WAS INVESYIGATED IN MITUCHONORIAL MICROS04AL FRACT1314 OERIVED FROM CHICK EMBRYO FIBROBLAST51NFECITE0 WITH EEE VIRUS. IN THIS F-PtCTION REPLICATIVE .,COMPLEX OF THE VIRUS WAS FOUND,AND THERE OC(-,IJRqEf) INTEt,"SIVE 10 VIRUS SPECIFIC RNA AND PR`.-,TElN-c SYNTHESIS OF CELLULAR. AN PRODUCTS OF THE SYNTHESIS INCLUDED RIBONUCLEOPROTEINS DIFFERING FROP. EACH OTHER IN SED.tMENTATJON-AND DENSITY CHARACTERISTICS., ONE OF RIBONIUCLEORROTFINS ~MJNTATION CONSTANT HAD-SEDI 1-60 S AND DENSITY. OF 1.43G-CMPRIilE3 WHICH TO"PARAMETERS- -OF RISIC'NUCLEFOPROTE INS OF.;.VEE VIRUS VIRIONS. UNCLASSIFIED .SSII.IG DATE-14SEP70 PRODUCTION OF LARGE ~SUSJECT AREAS--BIOLOGICAL AND MEDICAL,SCTENCES A ARBOVTRUSt VENEZUELAm EQUINElENCEPHALITIS VIRUSt R ON, TISSUE CULTURE I NTERFER CONTROL MARKING--NO RESTRICTIONS OCUMENT CLASS--UNCLASSIFIED --1q87/,0052 --UR/0402/70/000/001/0034/0038 PROXY REEL/FRAME STEP NO. CIRC ACCESSION NO--AP0103732 UNrk,'LASSIFIED 212, 012 .F PROtESSI~- DATE--IISEP70 UNCLASSI xl~o J :CIRC ACCESSION NO--AP0103732 ~,-A6STRkCTJEXTRACT--(U) GP-0- ABSTRACT* OPTIMAL CONDITIONS FOR PROITJCTIO~4 1IF-INTERFERON INDUCED BY GROUP A ARBOVIRUSES IVEE, -AND SINDBIS V)'~,USES) IN -PRIMIARILY TRYPSINIZED CHICK E.14BRY0 FIBROBLAST CULTURES USING DIFFERENT METHODS OF CULTIVATION. (ROLLER SUSPENSFONS1 MONOLAYER 'STATIONARY CULTURES) WERE STUDIED. THE MOSTIMPORT~ANT FACTORS THE LEVELS OF INTERFERON PRODUCTION WEkE FOUND TO BE THE _VJABILITY AND CONCENTRATION- OF- THE CELLS,(CALCULATED PER I ML 03P THE EN SUSP.-NSIONS MEDIUMI. TH EMULTIPLICITY OF INFECTION, IS IMPORTANT WHE _-.AttE US*E0-AND .15 OPTIMIALLY 1 10. PFU-CELL..- :INCREASING OF--- INCUBATION INDUCED BY SINDBIS VIRUS, "u. '-- u C~S PRODUCTION.OF INTERFERON JEMPERAT RE.ENHAN WICLASSIFIEf) 576.5-58 USSR. L VERSH-0-V F URTIAYHEV, L. V., and ZHDANOV, V. M., Active 'Xiember, 1e-Z-dT M r~- Lo"i"A M, e d i c a ISciences USSR and I)R'YL*Din8titate of Virology NOV, 'I. 4M ::i eni D Ivanovskiy, Academk of Medi6al'Scienco-s, Mloscow M ".Cytochemical Analysis of Structures Isolated: f rom Cells Infected with Arbovirus" lqoscow"L Doklady Alcademii Nauk SSSR, Vol 190, N' o 1,: janj'Peb 70, pp 212- 213 Astract-. ""Lie morphological characteristics of fraction isc- th Venezuel n equine lated from chick embryo f1brobInsta infected wit encephalomyelitis virus, were studied-wit'a ti-Le heLp of phasa contra.%,."L and 1"luoresce"ce micvorcopy. ChLick embryo fibrob).,--sts and cells ((o 3 i! SjVj~ ootained three hourz; after infect-ion 0, t1le 'ArUs W were di-s-i'nte8rated in a homo-enator, and the nuclt~i, di!bris, and whole remaininy cells were centrifuged for 1-0 Minuten. Ti'e CC-15 fraction was obtalfried by the subsequent centriEugation of 1:1he ho~.,iogrenate, rius- pension in 199 medi= , and straining, with: acrie-in~-. oratij:r,~, pho-sphirte 3P, and homologous antibodies labelled vrith. fluori~$cei.n isothiocyanate. Tart o44' the preparation were stained with' Janus green, or prered by 1/2 m--- 7T USSR Y&RSFOV, P. et a!., Moscow, Doklady Akademii 1,9 U 'vol 190, L 1-40 1, Jan/Feb 70, pp 212-213 by the crushed drop method and st"died by means olf phase contrast microscopy. acaminations showed that cytoplasmic of wliole cc-LIS ta4ned with acrid-'ne orange fluoresced ruby-red, Mhile the RNAI off the nucleoli -- brick-red, and DNA of the nuclei Phosphine 3P produced a greenish-brown color in the cy-toplasm and a aark-broi..,n calor in the cell nuclei. VLuorescenc,,'-_, microscopy of the debris and and nuclei obtained after homo(renatioa~ showed 1--r-e- congLo- en (a Maraten of cytoplasm, which were ruby-red. Fraction M.1-15 ztained with acridine orange revealed under phase contra.9t microscopy a ma-~,s of raby-red granules scattered through the entire field oe vision. T.lhlen Y Stained with phosphine 3P -- single brightly fluorescing lipid granu- les were observed. A considerable increase in ti~.,e nwiiber of lipid granules was noted when the CC-15 fraction from infected cello was studied by fluorescence microscopy The presence of a specific virus antigen was observed in the CC-15 iraction treated writh fluorescein ttered mitochondria were observed throughout the isothiacyanate. Sca%.~ cytoplasmic network of fraction CO-15 preparations stained with janus green. 2 /2 n 046 UNCLASSi F 11-0 ORdtiEsstING DATE--20NOV70 C LRC ACCESSICN NU--AP0112455 A6S.TRACT/EvT;lACT--(U) GP I ABSTRACT. ANALYSIS IN A RUBY S H GW I NG 7HAT SUPIJECTED TO THE STIMULANEOUS EFFECT OF LAS,E:R AND ACOUSTIC ~PULSES, THE SOUND IMAY' EXPERIENCE. RESONANT ABSORPTION AND CAN CHANGE THE 01,~ECTIGIN (;F -SHE SVijNTAtqEUUSLY. FAETTED SHORT LEGHT '.,:PULSE-. THIS SHOULD MAKE IT PCSSIBLE To UETERMIINIE THE INTENSITY 'OF. LASEiR EMISSION, BY MEA~~'UkING THE ACOL; -STIC FRE.,)UENCY,# AND-TO STUDY THE bEHAVIOR OF SHORT LIGHT PULSES IN RUBY~ AN EXPERMENTAL PROCEDURE F(IR THIS PURPOSE IS -T 0 M ElA NAUK :SSSR F J;Z I KG~ FACILITY: -AKA.E EK HN I C HESK I I -TITUT, i~AZAN# USSR.: 'CLASSIFIED N U 021- UNCLASSIFIED PROCESSING DATE--04DEC70 ACCESSION NO--AP0126161 SIGNIFICAtTLY ~-AISSTRACT/EXTRACT--(U) GP-0- ABSTRACT. IN ORDER TO INCREASE :-THE SENSITIviTy AND THE Jf-,CCLlRACY OF THE VOLUMTERIC~ METiHOD DURING THE STUDY OF THE TITLE PROBLEl'it A RING1,1KE SLIT WAS EMPLOYED FOR TPE ~.,~ATTENUATION OF THE COlNlVFClI(3N IN THE MELT INSTFAD.lOF A CAPILLARY9 FORMED BY -2 COAXIALLY LOCATED CORUNDUM TEST TUBES, THEREI'~Y MAKING IT POSS111LE TO WORK,WITH LARGE MASSES OF THE LIQ. METALS.~ THE'DIS TANCE BETWEEN THE TEST TUBES WAS 1.5-2.5 tili. PRIOR TO ENTERING THE-TEST~TUBESt THE IN USEO _i4AS PURIFIED OF 0 AND MOISTURE. JHE INTERNAL~ TESf,!'.TU8E- SERVED ~oSIMULTANEOUSLY ALSO FOR liNSTALLATION OF A'.W-RE THE~RMOCaLJPLE. THE METALLIC MELT WAS FORMED FROM CAREFULLY..PUR.IFIED &LECTIZOLYTIC FE WITH IT. THE TO:TAL IMPURITY CONTENT OF LESS THAN O'l WT. PERCEN TYPICAL TESTS -WERE PERFORMED,AT 1600 AND 1650DEGREES. THE,DIFFUSIOM COEFFS. FOR N IN FE WERE CALCO. THE ACTIVATION ENER.GY OF N 4.).IFFU.StON WAS 11.0 IKGAL-,MOLE. THE JEMP. DEPENDENCE OF-THE AVERAGED DIFFUSIUN COEFFS, WAS DETO.-THE DIFFUSION MOBILITY OF N IN MOLTEN FE 15~tSIGNIFICANTLY LFSS THAN THAT FOR THE REMAINING GASES,~ THE 'DIFFUSION (1,0EFF. FOR N WAS 5.5 'A TIMES 10 PRI14E NEGATIVE5 AT IbOODVGREES AND 6.3 TIPIES 11) PRIME Ner, TIVE5 AT 1700DEGREES. THE DiFFUSION COEFF$la OFJi AND 0 AT :1600DEGP.EES ARE 1 32 TIMES~ 10 PRIME. NEGATIVE3 AND ;t.22 rIMES 10 PRIME ~,NgGATIVE4 CM PRIM;2-SECr REV. OW,TKE OTHER, HAND,~ JHE, Dl FFUS I ON~ COEFF. FOR7, N-IS -SIM ORDER OF~NAGN LTUDE;t A ,RG E-RTHAN :,TI,'HE S:E'LF DIFFUSION -Pi., Of~ -FEI J.HE.---LATTER 1.7' TIMES" 10': PRIME N": OA T I VE 6 C M -SEC AT 16200EGREES. UNCLASSIFIED 2r --AT L t 16 519 F_x _-4 f T AN f j THE ACCURACY 4A CAPILLAR T~ K, j C., u, MW it f ~O:r_ st -!fFE aT D, 0*1 A F~: C C I T HE a I F Fli S I r-HEl AM T p OF: 4 A ~`!S 0 KO El~ C.!j t3ti 14 f11 k /I ~ E Ll N 4.5 1 y Our L W811 E: UALS 5~21 E_$:l 1-0 1.4E, NFG,4_1 INE2 CA P CM i u(IS I Q, U -00, i1i T I TKE AdTIVATION :J-NFPr;,' li 0 TK C, L P, 1 .1 ah qs.Lr-., Lf fA.- 1. .5, 1. A(; F R AN' $ V 3 N' A 0 SUDI L-fl 1~4 JS AN ADDITIVE, CvfARA(_TfA,.l:'~T C-OUIE rta THE EXI-ST 1.1 fltji~ CILUSTER5v PST SURCLr Ahe, Ell PSA sufl_~)sss' w4ERE PSI ui! p il u PSI svsDis z;, RIALS 1# 0 E4"ALS '51 Vja(;L 0 u ?sF i~Dls 0 SL111401s. FACILITY.- DONE I'SK, F I T E K H I N 5 T 0 .q f T K tj$r.R pie, OCES'.SING DATE--IISEP70 OF PRODUCTION OF LARGE TOPIC TAGS--GROUP A ARBOVTRUSI VENEZU.ELAN EQUINE E14CEPHALITIS VIRUS, MTFRFFJZ0M. TTI;-',UF rUl TtJqF ,,~,,PROXY REFL/FRAME--lq87/0052 STFP ',4r)--UR/0402,f7O/OO(,/Qr)l/()03,t/r),l-A8 CIRC ACCESS ION NO--AP0103732 UNCLASS I F lFD UNCL ASS] FIE D' PROtESSIN' DATE-11SEP70 ~,_CJRC ACCESSION NO-AP0103732 ---.,AGSTRACT/EXTtACT--(1J) GP-0- ABSTRACT. OPTIMAL CONDITIONS FOR PROOIJCTfCl~4 ~ -00 INTERFERON I N DUC ED By rROUPAARBOVIRUSES (VEE AND SIN-)BIS VIRUSES) Z IN PRIMARILY TRYPSINIZGD CHICK EIMBRYO FIRROBLAST CAJLTUR~-S USING DIFFERENT METHODS OF CULTIVATION (ROLLER SUSPENST011S, MONDLAYER STATIONARY CULTURESI WERE STUD!ED. THE:MOST IMPORT'ANT FACTORS DETERMINING THE LEVELS OF INTERFEPON PRODUCTION WER H E FOUND TO BE T E VfABILITY AND CONCENTRATION-OF THE CELL$ (CALCULATED PER I ML rIF: THE ME D I UMAI. THE MULTIPLICITY OF INFECTION. IS IMPGRTAtlT WHE-1-1 SUSO-NISIONS ::-APE US'Ef) - AND .1 S OPT li','.ALLY 1 10. PFU-CELL,.. ~ I NCP E AS ING OF-,, I NEUBAT I r)NI TEMPERATURE ENHANC5S PRODUCTION OF INTERFEROIlt INDUCED BY. SINDBIS VIRUS. UNCLASSIFIED USSIR UDC 576*.55S L. V. YERSFOV, r. nd, ZHDANZOV, V, I.' ctive Member, A MY74-oTMedical Sciences USSR and' DRYMOV, 1. D., 'Institute of Virolo,7,y imeni D. 1. Ivanovskiy, Academy of- Medical Scipaces, MOSCOW 'D ."CYtochemical Analysis of Structures Isolated from Ce-Us In-L"ected with Arbovirusil Moscow, DoIclady Akademii Nauk SSSR, Vol, 190, No, I., jar~/IFP-b 70, pp 212- -bstract: The MOrDhOlOgical characteristics of traction CC-13, iso- lated from. chick embryo fibroblasts With VC1L1ZUe-1-a-'1 equir'e enceph.-.10mye-14-tis virus, were studied with. t'%ae help of pha5e contrast and fluorescence raicroscopy. Chick erabryo fibrobl-a3va. id. cc', Ls ar obt-ained three houra ifter in-fection witK maissivn~ doses af.' tLe vir~ls were disintegrated in a homoaenator, and ~ the nuclei', dt!bris, and w1hole remaining cells were centrifuged for 10 minutes.~ : ne C%C-15 fraction was obtained by the 5ubscquent centriftirration o.E the homorrenate, sus- 4~ C~ 199 madium, and straining pension in Wi th ~ acrida".me crange, phosphine z 3P, and hom4ologous antibodiea labellea-yith fluor ",cc-in,isothiocyanate. P, rt of ~'th' --a -he preparation.ware sta e wi Janus g~,ecn, or prert~d by .1/2 us S RI ".1,08COW, D Iclady Akade'mii 11;~-';k "MR, Vol 190, YEIRSHOV, F. 0 No 1, lan/Feb 70, pp 212-213 bv.the crushed drop method and studied by means of phaac contrast -led tt-tat Y-6plasmic T'~Ul of 1"'LOIC ce, S Tacroscopy. 1: _naLions shot C t d i-h acridine orange 2luoresced ruby-I-ed, the R'Mk of _~s aine w L the- nucleol-i -- brick-red, and DIMA. of 'tlia ~naclei -- ~_,riaranld-rcen. Phosphline 3P prcduced a gree ni s h -brown color 'in the cy%-aplasm and a dark-brown color in the cell nuclei. Fluores%:-ence. microscopy of t1he debris and and nuclei obtained after hamogenation+:sho-ved Iarga conglo- MZr CO-15 stairied with rates of cytoplasn- waich Twere ruby-red.,: Frac'L:io% acridiv~e orange revealed under phase contil-ast microscopy a n1ass of ruby-red granules scattered through the entire field of vision. ained with~ phosphine 3P -- sir~gla brightly flucrr-Lscin- lipid z~anu- t :1 S mib les were observed. A considerable. increase in the nk. ue of Upid les was noted when the CC-1.5 fraction Irom infec~.-ed cells wa-s Zranu .C studied by f-luorescence m1croscopy. The prCS~MCLI O.L i~'i 6j)CC111C Vl'~UG arttigen was observed -he CC-15 fraction treatlL-d wfth ftuore,-cein isothiocyanate. Scattered mitochondria ''were obs4irved throughout the cytoplasmic network of fraction. CC-15 prepax~atio.Its stained with janus 2 =44mm , I WrAnumm 112 046 P. A0CE$SJNCi. DATE-20NOV70 ,~.Tl TLE--ACGUST 1C ELECTRIC FESONIAINCE IN A: LASER PULS~& F I ELD~ -U- -102)-YERSHOV, G.to-t KUPVlLLtMv U.KHO ~,_AUTHDR CGUNTRY LF INFC--USSR TVERDOGO TELA, VOL.:129 MAR. 1970 P..931:l 932. :.DATE PUBLIS~iED----MAR70 :-SUBJECT AREAS-PHYSICS .,-TOPIC TAGS--LASER PULSEi ACCUSTIC RESONANCEr RUOY, RtSONANCE ABSORPTIONP RADIATIEN INTFNSITY# MEASUREMENTv AC=(TIG f-,RkUEW~Y, Lit-311T PULSE :~`_CtINTRCL'MARKING-NO RESTRICTIONS DOCUMENT- CLASS--UNCLASSIFIEL-1 PROXY REEL/FRMME--l9q2/1461 STEP NO--UR/OLal/70/t)EZ/OC)0/0931./0932 C IRC, ACCESS MIN NO-AP0112455 UNC L4S.5 IF 1'~ 1) -3 021 UNCLASSrFIED PROCESSING DATE-04DEC70 ~_,_CJRC ACCESSION NO--AP0126161 ABSTRACT/EXTRACT--(Ul GP-0- ABSTRACT. I N OROER TO INCREASE Sl(;NIF-I'A~4r LY THE SENSITIVITY AND THE ACCURACY 01F THE VOLUMTERIC ~METHOD DURING THE STUDY Or- THG TITLE PROBLE-ilt A RINGLIK,E SLIT 14AS EMPLOYED FOR TH.1' ATTENUATION) OF THE COiNVECTION IN THE:MEL'T INSTEAD.OF A CAPILLA~iT FORiIED BY 2 COAXIALLY LOCATED CORUNDUM TEST.TUBES, TliEfZE8'e MAKING IT POSSIBLE TO WORK WITH LARGE MASSES 0.-,:: THE LIQ. METALS~. THE DISTANCE aETWEEk~ THE TEST TUBES WAS 1.5-2.5 MUM. PRIOR TO EINTERING THS.TEST TUBES, THE N USEC WAS PURIFIED OF 0 AND MOISTURE. 'v THE INTERNAL TEST TOBE SERVED ALSO FOR INSTALLATION A,, w-.qF- THFRM0,COUPLE. TH E -P T [C F E - I TH ETALLIC MELT WAS FORMED FROM CAREFULLY FIE0 :ELF-Cl QLY ti PUR I T .-THE T,bTAL IMPURITY CONTEN, OF: LESS WT. PERCENT. TYPICAL TESTS WERE PERFORMED AT 1600 A1110 16500EGREES. THE DI.Fruslcim COEFFS. FOR N IN MOLTEN FE WERE CALCD. THE ACTIVATION. ENEPGY'OF N OfFFUSION WAS 11,0 KCAL-MOLE6 THE TEMP. DEPENDENCE OF THE AVEPAGEO 0IFFUSION COEFFS. WAS I JFICANTLY LFSS _0ETD. THE DIFFUSION MOBILITY OFN IN~MOLTEN FE 15 SIGN THAk THAT FOR. THE REMAINING GASES. THE DIFFUSION .COEFF, FOR N WAS 5.5 -TIMES .10 PPI14E iNlEGATIVE5 AT 1600DEGREE-S AND 6.3 TIMES 110 PRIME NEG~ITIVE5 CH PRIVtE2-SEC AT ITOODEGREES. THE DIFFUSJON COEFFS. GF~H ANo 0 AT 'GR -,-_1600Dr , EES ARE' 1.32 TIMES 10 PRIME NEGATIVE3 AND'! .22: T114ES 10 PRIME ON T H E 0 ~i ~NEGATIVE4 CM PRIME?-SEC, RE!~?. THER I AN-0 THE 0IFFUSION COEFF. FQR~ fl IS 5llMIL4R L PRO-., oi.A'GNtTlJDE LARGER THAIV THE SELF DIFFUSION CGFr-F* OF FEv THE LATTER BEING 1.7 TIMIES 10 PKIME'NEGATIVE6 C01 AT 162DOEGPEES* UNC LAS S I F1 ED 1/2 024 UNCLASSIFIED PROCESSING DATE--160CT70 ,TITLE--HYDROGEN DIFFUSION IN MOLTEWIRON -0- AUTHOR- (04) - ARK HAROV, V.I., NOVOKHATSKIY, I.A., YE* ~OVALENKU, ~"UNTRY OF INFO--USSR 1329-32 ~-SOURCE-DOKL- AKAD. NAUK SSSR 1970, 190t6), ~~'4TE PUSL ISHEI)----- 70 1".'SUB-JECT AREAS--MATER,IALS TA,GS--HYDROG,EN, GAS DIFFUSIONt FERROUS LIQUID.,AILETAL, 'RON, 14ETAL '',:~~.CONTAINING GAS, GAS CONTAINING METAL A-OL 14ARKING-NO RESTRICTIONS -UNCLASSIFIED OCUMENT CLASS ;~.-.PRGXY-REEL/FRAME-1995/1134 STEP NO--UR/0020170/190/006/1329/1332 :C-IRC ACCESSION NO--AT0116599 UNCLASS IF IED 2/2 024 UNCLASSIFIED PAOCESSING DATE-160CT70 ,,,C,IRC ACCESSION NO--AT0116599 -'ABSTRACT/EXTRACT--(U) GP-0- ABSTRACT. THE SENSITIVITY AND THE ACCURACY OF THE VOLUMETRIC METHOD USED INTHE STUDY OF H DIFFUSION IN MOLTEN FE WERE INCREASED BY THE SUBSTITUTION OF A RING GAP FOR THE CAPILLARY. THE ..ANNULAR SPACE WAS FORMED BY 2 CONCENTRIC TUBES. AT 1560-1650DEGREES, THE WIDTH OF THE GAP FILLED WITH MOLTEN FE DID NOT AFFECT rHE DIFFUSION COEFF., D SUBH. THE AMTs OF H ABSORSEOt.V SUBHt INCREASED LINEARLY WITH TAU PRIMEDNE HALFt WHERE TAU IS TIME. EXPTL. D SUBH EQUALS 5.21 TIMES 10 PRIME NEGATIVE2 EXP(MINUS 101000-?,T)t. THE ACTIVATION ENERGY IS 10,0 KCAL PER MOLE. rHE U SUSH IS LARGER THAN 0 SUSN AND 0 SUBO. DIFFUSION IS AN ADDITIVE CHARACTERISTIC DUE TO TH&EXISTENCE IN THE ~MOLTEN FE CLUSTERSt PSI SUBCLv AND DISORDERED0 PSI SUBOISi REGIONS, -WHERE PSI SUBCL PLUS PSI SUBOIS EQUALS,I., 0 EJUALS PSI SUt3CL D SUBCL -PLUS PSI SUBDIS D SUBDIS. FACILITY: DONETSK. FIZ.-TEKH. INST., 0QNETSKv.USSR. UNCLASSIFIED mx;c. N a ~Serv Lce Ref Code: s' INTERNAT.~AEIROSPACE ABST.-~- 7,0 4, su OY nn 470-~4271 Effect nMe of visccmty of metallic melts (VIiianie nemeto!l!"kiiih vkliuthianii na viatzkost'metallicheskikh raiplavoo' Ve I' Arkharov G, S, Ershov, 1. A. Novokhatskii, and A. M. Kboafenko (Ak emiia Nauk Ukrains-koi SSR, Firiko~Tekhnicheskii Institut Donetsk: Ukra ' kii Nauchno- ov Khaek6'v.' O~iaini:in Issled '-atel'skii Institut Sbe6ia,nVkfi-S ssii). ~4kadernjja 16~k S,~jfi 7 0,2klady, Vol. 190, Jan. 11, 1970, p. 366-368.6 refs. In Russian, Study of.the kinematic viscoi:,ty of molten sivel of a single composition containing. various arimunts of nonmetallic oxide (mainly corundum) inellusions in'. the tei Inperatureranq~-. from IC00 to 1825 C. The viscosity values were determined by, the metht.)d of torsional vibrations of a crucibla, containixsq liquid metal in an, in,!rt atmosphere. It is found that the viscosity of liquid steig in&aates substantially with an'increase in the quantity of corund;jrn dispt!rs4YJ in it. This relative increase in viscosity due w tile. presencit of nonmetallic inclusions decreases with an increase in temperature. A.8,K. 'REELMME