Subprolact 21- Description Date Obligations Expenditures Balance , ce-try Au- 7,20,0o if It is proposed that the be provided with fund the study and.eValuation or certain persops released by ist bloc countries. The cost of the work con. mplated in this project is as follows:- --- Personal Compensation - -2120.00 Travel 2000.00 _ Miscellaneous 1000.00 Ttital $5/20. 00 1.04011AIMUIllat : THE RECORD : Project M1CULTRA; Subproject. #21 1. The aim of this subproject is to provide funds for an increase in the scope of that portion of Subproject 48 which deals with the over-all-returnee interrogation and re- habilitation program now being arried out by the Since impossible to estimate in advance t e num er of subjects to be handled under this program/ it will be necessary_to_enlarge _ its scope from time to time. 2. Subproject 21 was set up originally fo t of providing a drug screening facility at the The total cost of the program amOun ed to 572 .00. Unfortuna elyi-internal-politios at the made it im- � possible to carry out the program, as plann i And so no funds were over expended in this Subproject. The basis for the change of Subproject 21 frOm its original goal to the present one is based upon an identical case where Subproject 10 was converted ,9 for use in the project after it became evident that the funds couitted un it originally for another purpose could A not be used. has since audited Subproject 10 with- out qu.stioning this type of handling. ;- 3. Accounting for funds-expended by the contractor in this subproject will be reflected in the general accounting for Subprojeot 48. . 4. The-tatal charges for this project will not exceed $5720.00 for a period of one year ending 30 June 1956. 5. the PrihPiPele in this proj o are TS cleared.. Cut-outs and cover arrangements will be used for dealings with unwitting personnel. Al:PROVED FOR - .OBLIGATION-OF FUNDS: Date: o� TSS/ :111 Distribution: Original Only Obetioal-Divisi0 1 January 1955 14VIMNDUM FM: TliE RECORD SUBJECT Extension of Time for Project HKULTRA,-SUbproject 21 Since_SUbproject 21 has expired and there are Ain__ �binds remaining in the project, Subproject 21. is berehy extended for one year from date of ekpiration. APPROVED: Original Only PRAR11AC0LOOICAL TESTV0-OF OFFii0T kPEUTIC AGE= FOR GiV The principle investigator, is familiar 'with the diphenolic compounds originally syntheSied4t-the under the direction of. and is fully C! equipped to proceed further the pharmacological testing and bio.=assay of such - compounes. It is purposed to test the LD/50 and the pharmaeolozical action such compounds and related chemotherapeutic agents a3 ray be -submitted from time to time through the Pathology. Department _at r modified by the principle investigator. Detailed reports and records util be kept on the bio.Assays and pharmacological tests and submitted as they - become available. The budget desired for-this research proposal is: Personnel labordtory_assistant $3,000,00 pf:r nnum Animals and aniAli maintenance 1,000.00 Miscellaneous laboratory_ supplies 500.00 Travel Total Institutional overhead lO% is an associate of the conduct the work in the facilities of that, organization. 5,000.00 500.00 and will UTEMORANDUM FOR THE RECORD SUBJECT: Project tXUTJTRAJ,1 Subprolect 21 1. The scope of subproject 21, Project UKULTRA, is to pro-- vide CD/TSS with a facility where the pharmacological activity of various materials of interest to the division can be determined in a secure and complete fashion. 2. The chief investightor, routinely con- ducts such,te ts on large numbers of materials in the laboratories . of th- before the materials are -,13 screened for anti-cancer activity. _Thus, any materials fro% CD/ TSS can be included in this larger_ grouporithoutAheir true iden- tity being known to anyone outside the Agency. 3. All busine4s-with will be conducted through acting as cut-ou . The attached proposal indicates 't,he distri u ion of funds. In addition to the $5 500.00, a 4% service -charge, or -$220X0, for th is required. 4. The total cost of-this-project for one iear ending-1-Janu- ary 1955 will not exceed45i720-iOO. 4.. PROGR.A3L. AY-PROVED AND RECOVIENDED: Attachment: Proposal SIDNEY GOTTLIEB Chief Chemical Division TSS APPROVED FOR OBLIGATION- OFIFUNDS: Research 4rector tate: ,2/ WV--) _ the authority granted in-thS�memrandtte dated 13 April 1953 from the MI to the DD/A, and the further authority granted in the memorandna date4 17 4ril 1953 !rime the vp/A to the Comp.-. - troller en the subjeets npft.Tss Project UXULTRAi� and the ne.. mormrAmdsted 19 June 1953, from the ra to the DO extending the aathority to cover Fiscal Year 1934 Cubproject 21 has been approved, and 13,720.00 of the over-all Project MULMRA fUnds have been obligated to cover the bproject's expenses. :ROM) SIDNEY GOMM Chief Chemical Division, TSS APPROM-Pat OBLIGATION ARV RECOUMIDEDI CY_ FUNDS: Listribetioni Addreasee tri Exec. Seely., TWV4dzet TWRegistry TWCD - Research Dire if � DEC 21 ENID 7

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MKULTRA SUBPROJECT 21 (8 DOCUMENTS WITH PUBDATES FROM 531210 TO 550623)