MKULTRA SUBPROJECT 124 (25 DOCUMENTS WITH PUBDATES FROM 600624 TO 64100 8)
Document Type:
Keywords:
Collection:
Document Number (FOIA) /ESDN (CREST):
00017382
Release Decision:
RIPPUB
Original Classification:
U
Document Page Count:
40
Document Creation Date:
August 23, 2024
Document Release Date:
September 8, 1976
Sequence Number:
Case Number:
Publication Date:
June 24, 1960
File:
Attachment | Size |
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Body:
INVOI0.11 faTii!.101( LIST
JLT,14 eub-vojact.
At
Dste of Original
Authorization
Autlx)riv.;�setots
rxtended
Covercd
Allotnzmt ,Aloint of
DIritizrO1tczticfl
Ti=t F,xtz,rAccl Allotmant
Cove:es/ To
invoirn rimbez* Date
Lte4:9 / icVa � 2 Z.- ,
Pzaunt-a
Obligation
1
Arocunt
palwee
- $13
/2
MATRA, Subprolect Ik4-
_ -
Purposa:- To develop a more sePhistic,m.,-
%dioxide tension and pH of body fluids; to study
pH and psychophysiological variables. �
Initiated: September 1960
Contractor:
Cott: $6 500.00
Status:
TO:
1. Date of Obligation: 11/41/A .01�041010.101.1���ressINSIVRES.
2. Purpose of Project: Research-in -"The
boIo1,icOrre1aSOf
.
Carbon Dioxide Environment"
����11�����4�1,�E
3. Progreae to Date:_amitet
ted.
4. Expiration Date:..,
5. Project Monitor:
FROM:
ss k
�
(When Filled In)
ACCOUNTING BY I ND I V I DUA I.
FOR ADVANCE
1WOTR: Follow Instructions on Reverse
UB TTE HY
toMUL"aA,_ oravrozact in4
DATE � VOUCHFR NO, 2.12
- (.4
,.. , 6'r i
.4.1
PERIOD OF ACCOUNTING
r25/ . mr, ao
FROM
1 t963
TO
cber._2.965
I. OASIs ON HAND BEGINNING OF PERIOD
,537,-.72
. 5. EXPENSES THIS PERIOD;
2 OUTSTANDING ADVANCES BEGINNING OF PERIOD
VOUCHER
NUMOER
DATE,,, DESCRIPTION AMOUNT
3. RECEIPTS. THIS PERIOD;
Mitts 497'n
,
Refund te
RE rIPT
NUMBER
DATE DESCRIPTION
[-760�ACL-25-72C285
� 4 ' 40444coi
12
180.0 /Vat
TOTAL EXPENSES
2 37.7
I6.
REFUNDED HEREWITH 1 1 CASH 'CHECK [NONEY ORDER
,
1 7. OUTSTANDING ADVANCES END OF PERIOD (Attach listing)
1
. CASH ON HAND END OF PERIOD OR BALANCE DUE AOVANCEE
4. TOTAL TO ACCOUNT FOR
$
sr.
9. , TOTAL ACCOUNTED FOR
LL " 537-T9
I CERTIFY FUNDS ARE AVAILABLE,
1 APPROVEO
I certify that the expenditures listed hereon an
OBLIG.REF. NO
. 533
CHARGE FAN ACCOUNT NO.
1125-1395-3932 ,
00,60
DATE
SIGNATURE
OF APPROVING OFFICER
!credit
ts v64 C4 V (DN. *Niro
on any attachments were incurred for officiril pur-
poses of A confidential nature, that payment or
therefor has not been received, and thrpt
this accounting is true and correct,
DATE
SIGNATURE OF AUTHORIZING
1
!
OFFICER CERT FIED
*
FOR
PAYM NT OR
CREDIT 1
I
SIGNATURE OF PAYEE,
!
1
DATE
I
1
SIGNATURE
OF
1
CERTIFYING
OFFTC
R
1
SPACE LOW FOR
EXCLUSIVE
USE
..
OF OFFICE, OF FINANCE
DESCRIPTION.ALL OTHER ACCOUNTS 13.33
34.39
40.
41
42.47 .1
46.
49
50
51.54
. 1 155.66 , i 1
67.70
OBJECT
CLASS
71-60
AMOUNT
!
28,33 .
T/A NO.1
STATION
CODE
E
08LIG. ,
REF. NO.
* ..PER.
PAY
OA
OR
GENERAL
COST . FAN 1 I
ACCOUNT SYMBOL 1
DESCRIPTION .1
ADVANCE ACCOUNTS 13.27
, a
!
sH P.,06C.NO.
..... . .. ,4
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DUE DEBIT CREDIT
DATE
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PREPARED BY
DATE
REVIEWED
ny
1
TOTALS
(
/ 4) . ?
�
FORM ORSOLETE PREVIOUS
282
4.65 EDITIONS
11-491
CERTMCATION
1. This la to certify that X have received an accounting
fro% MKULTHA, Whproject 124 which refiecte expenase_of
$2,497.23* The accounting la being retained in the office of
?SD where it may be reviewed by the certifyfng officer upoe
request*
2* The balance remaining after recording the expenditures
has been refunded. *.t injhe amount of $40.54 ha2 been
recoried on rietary company financial
records*
3: 1 certlfy-that satisfactory serillces representedby____
the accounting have_been received and that to the:best of my
inoviedge and teller the fwide expended vere for the pwpoeee _
authorised by_the_projeot approval.
�
AloPSOM:
SIDNEY GOMM
DC/ra
WA present herewith the final accounting of the
Acittlesa_ItssearclA_Project.
Aacstioto-
1960 October
1961 Yebtifity
Diebutsements
1960 Itquipmant
1960 Evil:taint
1960 Other expend tures
1961 - No disbursements
1942 No disbursements
1963 is 746
Labor
1964
840
Labor
--9=12___Labor
248
9-14
6
si-11.23
ng Device
411.23
-Co
tent 6
11.43
onsultant
�-12-28
0
--12-28-
1965
- 1-21
or a.van
or subjects,
Dec30, 1965 Balance remaining
$3,250.00
3)250.00
$6,500.00
$2,449.16
1,300.00
213.05
158.00
441.00
222.00
208.00
25.01
302.93
100.00
250.00
22.79
78.52
600.00
a 60.00
_1_29 00_
867459146
Our check LD tha mount of $40.54, representing the unex-
pended balance, is enclosed.
Controller
Acid Base roject.
explains the delay.
inent on Mr
rharding thi ance
een away :on vacatiion and this -
The amount remaining in_the fund is
rat/
Of the the approximately $100,.0 expended since our last report,
over 951- has gone for payroll.
At the present time we are engaged in a study in which the -
background knowledge and apparatus provided in the grant.will be of
considerable use. We arc administering carbon dioxide and air in
mixtures up to HO carbon dioxide to hypertensive prisoner subjects in
an attempt-to study the tffect on resting blokx1 pressure leveit That the
acid base level is related to the resting rate of blood pressure is a
long-shot hypothesis.. If any effect is demonstrated,, ttlis could be an
important contribution. We plan to measure:Changes in the acid base
balance and blood pressure and particularly the length of titre that these
changes persist. There is some evidence (a the_Uterature that if one sets
carbon dioxide tolerance at a new level, that homeostatic mechanisms
will maintain this for a-considerable period of time. I will certainly keep
you informed of our results in this experiment,
I certify save teen iS ncerely,
satisfactoriay ' t C.:;;),nciitures
were incurred on offleil
Op ES
7-41IS AN Acc16-_,
I�REL. # srnic ,/
P4rsuantto-my-letter of April 25, I aM reporting to you
C% the AcidBase Study. - Dun i t two months ve-have-trained - -
a technician toxork_vith t student
in Chemistry this fall_atj We expect to
run experimental _subjects on
We -attempted ore experiment to simplify finger blood col-
lection by catching it under oil. This failed because -of oil
contamination-of-the-_electrode fore we will proceed with
subjects actording-ttetanda� thods, :
Ye
-PtindsA.emaining_in the_grant are suf icient for_the_next-
's studies,-.
Wevvill_report to you again on December 15,
nclosed please find the-a ounting fo rotl
'hich shows a' O'bslance: is should close Chat:ol
, . .. ,
Enclosed'is an a;c6unting :ID hich_l have madt u
since X had all his record i and 1 '. piyments for hist.
He may use;the.balanee up in sous small'axpen(Muies 'which
he his not4eCrecues d reiOursement for so 14ease.donit.
-
close-this-.one out.-
-'Enclosed alsojs A-copy_ofus letter Ito
which you can put In hi.sjjle4 Re is still spendlliu2r
g _ rant itoney and won't account until it is all gone-.
_ .
,
test Iiiiroonal. 'regards
(When Fi
n)
ACCOUNTING BY INDIVIDUAL
FOR ADVANCE
MODES Follow Ins ructions on R
SUBMITTED BY VOUCHER NO. (FinAnce use only)
Mail.= ezb 324
PERIOD OF ACCOUNTING
FR
1 Oetotor1.9.S2
[TO
St. ;Iva 1..3
RECEIPTS
DISBURSEMENTS
I. CASH ON HAND BEGINNING OF PERIOD
NYOW
DATE
DESCRIPTION
AMOUNT
a.
. RECEIPT
NUMBER
DATE DESCRIPTION
,
oct Atts=boa Car4�,,,Ifioatotoa
.
via
MEN MON (Mai) .
MIMI
ip
iiiiiMMEME
1-11.
El1111 ,
1
TOTAL EXPENSES
I!
11=11111=11111
3a.
A. REFUNDED HEREWITH CA" EMI
ME
. CAS ON HAND END 0
PERIOD
' 1 I:I
1 TOTAL TO ACCOUNT FOR
'0
II
1 TO,
AL IACCOUNTED FOR
clounloi
I CERTIFY FUNDS ARE AVAILABLE
1I I
APPROVED
1.! h
1
tl certify that the expenditures listed hereon and
OBLIGATION REFERENCE NO.
.
CHARGE ALLOTMENT
I
122344.,0-3902
NO.
, .
,
.
DATE
IGNATURE
Mira
'
OF APPROVING
0=0313
OFFICER
1 ' A
'
,;...
,:on
iinyattachments
,p cntemi. !olja: Iconfidential
ciedittherrtior
this sucuuniing
were incurred for official
nature, 4thst
has not been received,
is :true and correct.
per.
payment or
and that
DATE
SIGNATURE OF AUTHOR 1 Z lt4G :OFFICER
CERTIFIEI
FOR IPAyMENT
OR CREDIT
,
SIGNATURE, OP PAYEE
DATE
SIGNATURE1!
0 CERTIFYING,
OFF IC
R
0
,
/44
I SPACE
BELOW FOR EXCLUSIVE
USE OF FINANCE, DIVISION
PREPARED BY :
'REVIEWED
1y
H
�
1
:VOUCHER NO. 7.12
:1 I
DESCRIPTION' - ALL ClIrM R ACCOUNTS 13.33
.
14.30
40-42
43
44.44
47,.7
SA.S7
,
SO-47 �
10-70
DUE
71.4o
I
28.33
Tja No
1 STATION
1 CODE
EXPE
,Ir
PAY
RfP7
iio
c.I
....
GTRAL
ALLOT. OR COST
ACCT. NO.
DATE AMOUNT
DESCRIPTION � ADVANCE ACCOUNTS 13.27
....%.
P� Z. ho.
...
/ � 132.33
DIV.
...... ....
� *or . d No.
PROJACT No.
COD:
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ci
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2- 67
CA. NO.
A otp,No.
'
',COCCI�
CLASS
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1 1 1 1 1 1 1 1 1 1 1
1
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TOTALS
F�RM 282 us. 'PREVIOU
D.01
ED
Grants Received
1960
1961
Disbursements
4S
'Total cost
Les �
an
Other e
Unexpended Balance
Is
$ 3,250.00
3,250.00
$ 6,500.00
$ 2,545.06_
1,200.00 1,300.00
117.15
11962.21-
$ 2,537.79
--
This &nt of accounting
fro ted. o the Fund
OMTIfy*tliat services or materials have 'Ueen
:sAisfactorily received an; tl7e expenditures
Mere 'incurred on official b,;siness,
Dater
RECEIPT
Receipt is hereby acknowledged of the following check:
- -
No. 038
Cost Account //472 �
Object Class
Date
Remarks and References
Obligations
Incurred
Obligations
Liquidated
Unliquidated
Balance
Z '7') PDC .1
_ . A
41/
4 sM:q0 � ao
a
- --
_
L
-
T
r
'
158ptb.r 1960
rs
_C
ATIVITION
IMAM
Finance Divieion
itCULIV4 thAlpre4cot 12h
Ikdar the authority granted in the latuoraryluat dated
13 ApIt 3953 troat taw DU to the DD/A, and the eXteasion Qt
this authority In601024iipatlt 100144.40, Suhprojeet 1211- has
been snowed and 46,500.00 of the over-all LM rot
Aulds has been obligated_to_cover the subproject's expenses.
Thu s obligation of fultds ebould-he clutvg04 to Allots:tent 154-
1004902*
APPIOVIID 1UTIOis
R20)134
Date
I CERNY THAT FUNDS ARE AVAILABLE! -
ORIGAPOti rif-EENC: �Sa.3 1966
MOGI 10 ALIOTmtr�rt
Distributiont
Orig 14 2 - Addressee
1 - TSD/00
- TSDAPAS3
AUTHORIZING OFFICER
_
cy-0
CONFIDENTIAL FUNDS POSTING VOUCHER
VOUCHER NO. 7-12 . DATE 2.6 VOUCHER NO. 7.12
:3,rr P 1,960 1
DE5CRteT10NA1.I. OTHER ACCOUNTS 1 s 34-39
STATION
43
40.42, F
EXPEND u
145.4 47.52
ORLIG.
PAY REF. NO.
PER.
53
54.57
GENERAL
56.67
ALLOT. OR COST
ACCT. NO.
66-70 71-60
DUE AMOUNT
DATE
DESCRIPTION-
ADVANCE ACCOUNTS 13.27
r A-L.
P"�' NO.
32.331:Ci'r:O.
DIV
CODE
P "
P' P�
CODE
I
LIO .
metm .
CA
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LEDGER
ACCT. NO.
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ER IT
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CODE
... ....
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CLASS
tit
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WI;
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:
EXPLANATION OF ENTRY
TOTALS
4
_6* � z
/57.64i5?,-4,,,
DATE PP
/? 9 16
DATE
REVIEWED RY
CERTIFIED FOR PAYMENT OR CREDIT
DATE
SIGNATURE OF CERTIFYING OFFICER
FORM
10-59 606 USE PREVIOUS EDITIONS.
140410PANAI14 $ -MN? PINANON Drixmom
VIA
SSDAudaet Officer
SMIZOT MIULSIVOul)project 3214 lavoice No. 1
Allotawat 1123-10093902
2. Invoice No. 1 to tbe swat a $6,500 covering the
subproject is attached. Bowler, clue to refunds of 45,073.78 froa
other projects (as per attacbstots) porwat sboul4 be made as
folicvs
16 St caber 1960
2. tbe�clecks shoulti. be forwarded o meg TSD/ search
Branch, through /Budget Officer, no later than libtirelay,22
Nopteaber 1960.-
3. Ws Is a final irvolce. Bowyer, since it is saticipated _
that a&litional fds vill to_obligateNt for this project the tiles
-thoulti not be closed.
Att4tcheentifi
invoice es C.ttitictts
DistritutiOol
Cris & 2 A&Iressee .
7;) 1 --TSD/FASS_
Chief
TOD/Beisearch Brae&
lel
I CERTIFY THAT FUNDS ARE AVAILABLE* �
CSLICATI04 gEFEUNCE No.
cliAGE TO AUONINT No. eftfajr.. "WA 'WA
ALITHORIZING OFFICER
CHECO /77i9WI 7: JNT OF:
R EC
t
DXVZS
UD/Budget �Meer -
- ;
XICUINNAilluboroject 1242 Invoice No.
� Alleteat /125400949Ce
Inv*lee No. 3 tthe amount of 46,500 covering the above
sebproject is attached. Bowyer, due to refund, a $50)73.78 from
other projects (sa per attachments) ;orient 41041 he Made OA
folloY*1
Ctthierts eittek it, tug $1,106.22
Able
4trorn on
IL The checks should be fomente4 to chief., TSDIgnesearch
Brunel* through In/ Budget Officer, no later -than l'hureW, 22
Se teeter 1960.
3.
This is a finsl Lavoie.. Novevori since it is snticipateil
that alifilitioaal ttv1fl b. oblif.steci for this iroject- the files
shokklil not be closed.
Attiebleatit,
& Certifications
Distelloutlotl
ctrigh 2 .., A44reetes
1 - TSD/FASS
X2XXX---
2 -TSD/R3 _
16 Sept fo)
CIRTIFICATIONS
(1) It is hereby eertifiedthetithiS-ie_involco No. 1 applyingto
NOMA, Subkroject 12k, that performance is satisfactory; that the
services are being accomplished in accordance vith mutual agreements
that a detailed agenda_of_the payments and receipts is on file in
Min, that the bill is just_and correct and that payment thereof
bee not yet been made.
Date;
Cbief,D/Beseahi3ranchnch
(2) It is hereby certified-that-this'invoice applies to MULTRA,
project 1240.vbic1I vas dilly approved, and that the project to being
tarried out in accordance vith the memormmium dated 13 April-1951, from
the DOI to the DD/A, and the extension of this authority in aUbsequent -
memoranda.
Dates
(3) It Is hereby 1Ufje4 that the wove,* under subprojects 39,
cat 65 have been satisfactorily ccupleted taxi returned mused Azad,*
However, aubprojeat vhich le still conttnutng Oao renAnded money.
Ulan:ore, It is re-T.1**VA that the sottounts ashwa belav on 1Prfoickt
NumberZ ot subpro$set 124 be ervilted to the subprOjeata as show
� belov.
Pro 'eat
- t
k#24111t -
4114Wa26 e
1:91.1.52
50400-
'CO
Auomint
5.23ce.1045.1
2502.55.
64502404u
9.2502.5,-902
theiuthcrtt grnt�d 5z the oalea de
ApiU, 193
-
fro" ,the the extoosionQf
,
euteevieut steoverdalyTrejeet L2 boa
%OA� of the overrall xictrom proct
beta oblitated. to cover the stavio,Sect's expeoses.
s 0?.1tottion of isiOtte'sbeell b Ar Ailoteent 1523.
DRAFT
15 September 1
MEMORANDUM FO Rf TI RECORD
SUBJECT : MKULTRA, Subproject 124
1. It is requested that Subproj�tl2ltbe approved to
support the_research_program-of
in "The Fsychophysiological Car-- -
relates of Carbon Dioxide Environment" in accordance with the
attached proposal.
2. This study-will-add-to-our methodological_sophiati____
cation for measuring-carbon-dioxide-tension and pH of Ibody _fluids
as well as our-knowledge-of some of the relationships between
blood pH and certain psychophysiologiCalrvariables mentioned in
the attached proposal.
3. This project will-be funded through th
fs
for cover purposes. The
ac ounting-for funds_expended_shalliconforMitOthe-established - -
procedures of that-o anizationi-Titleito any_perianentequipmeht -
shall remain %It
charges.
4. The total dost-of7thialrojectifor-Six months is esti-
mated to be $6,500 as indicated in the attached budget. Charges
should be made against Allotment 1525-1009-1902. Any unused funds
Viii be returned to th
n lieu of overhead
t the completion of the project.
5.
consultant to TSD
sponsorship of the
Attachd:
Proposal
- 2 -
as been cleared and has served as a
or a number of years. He is witting of true
Distributicm:-
Original Only
TSD Research Brench
Approved for Obligatio of___ _ _
Funds:
Date: 15 Sept.60
A Propoeed Study of the Psychophysiological
Correlates of the Carbon Dioxide Environment -
Of all the environmental footers which influence human health,
the most neglected may be ono of the gaseous constituents of the atmos-
phere - carbon dioxide. While the proportion of carbon dioxide in fresh
air rano only to 3/100 of 1%, the blood and the body cella carry_a_earbon _
dioxide tension uhich_would_be_in_equilibrium with an atmosphere of about
5% carbon dioxide.
Changee in the carbon dioxide_tension of_body fluids are related
to many physiological-end psychological processes, Over-breathing is one
of the concomitants of anxietYi TheForresponding reduction of carbon di-
oxide tension restate in vaseconstriction and increased &Tooth and stri.i
ated muscle tonusi-with the creation of many ptome. These symptoms may._
be extremely uncomfortable, and set to accentuate anxiety. This Lvlotousi
circle is very diffiCUlt to interrupt, voluntarily, since breathing is
largely an automatic function. We can interrupt it by increasing the carbon
dioxide content of inspired air,-and this is an important method-of-treat.- -
ingte anxiety states charaoterised byhyperventilation.
An in4ication of the wide-pread applicability of carbon dioxide -
inhalation can be seen from two examples. Spastics and victims or ?ark/n-
oon's disease May obtain appreciable relief of muscle tonus, for at-least
as naeh a 0i0 al hoursi through breathing a mixture of 5-7A carbon di-
oxide. The mechanism is that by decreasing the pH of the blood, more_
body fluid calcium is ionized and this is conducive to mascio relaxation.
Another use o.fcAibondi�itde inhalation lies in-the treatment
of classical migraine, tn this disease, the aura phase is characterized
by marked vasoconstrictioa of cerebral vessels which constitute part of
the tree of one or the other carotid arteries.Aural phenomena, each as:
usual seotomata, are a reflection of temporary cerebral anoxemia. -After
minutes to hours of vasospaam, the affected vessels becOMe-totallyexhausted -
and spring into varodilation. The painful phase of migraineAe-thought to
be an action en-pain fibers inthestretched walls of_the_vessels._Prelim-
inary observations indicate that inhalation o1, carbon dioxide in the aura---- -
phase of claesieal migraine.ean abort the syndrome bucausing vasodilatien
before the emeoth muscles of the cerebral v.:waif are-totally exhaaetad.
Research inAhiveffecte7ofitheivellular_carbon dioxidtieneiron-
ment has beennegligible.-Thierneglect-may_be_attribetable to -several
reasons: In the first platei accurate studida Of the acidobase.balanee-of: -
the blood have usealy regeired-a-eizeable-amount �f arterial blood. This .
is not easy to come by, since arterial panctare is a difficult and painful
procedure. In the second place there has been no sthple portable device
for providing carbon dioxide for inhalation. -- Finally, there has been no
o�-� ����
�
ecceerted effort by parzaceattoai companies to etady the problem, eince
no patentable darg is involved. Carbon dioxide is cheap omnipresent
ia the envirentent.
Long ago, one of_the applicants :worked on the acid-base balance
with micro methods and capillaryfinger_blood. The methods _were fairly ac
carate but very complicated-74e knew_that simple tethodsvould_be_perfected�
but were unable to do this ourselves. In May of 1960 a_simple Micro system
was rode available_in
We have developed and used a simple certable�eourceof_carbogen
and are presently_using it in explorations et_the treatment of migraine.
The situation_is ow ripe for a comprehensive s aduoiLthe-bio- --
chemical physiological, psychological and treatment aSpects of alteration - -
of the carbon dioxiderlevel of body_flaids.
It is proposed that the acid-base equilibria* of psychiatric _
patients be surveyed, using the new method of Variations
related to diagnosis and coerce of illness may_be readily_pereleved.--Then,
with the same kind of_patientsi-the-feasibility-of altering the acid-base -
equilibrium be carbogen inhalationvand the duration of alteration after
such inhalation, would be studied on patients on normal vehnteers. The
effect of carbogen inhalation of selected patients, especially spastice,
victim of migraine and patients with anxiety would be stadied with repeat-
;C:CA I a k. K. -14-44s�-�G�rt....
ed Oyalcal determinations of acid-ba -variables. Effect ofacid-base
changes on MO, EEO and blood pressure would be determined with_a poly-
graph wUch is already available.
In summary, the_primary_objective of the propoeed study i V)
explere the parameters-of acid-base psychePhYsiological correlates, tieing
a method 'which has just been While there are specific treat-
ment objectives,-such as in cases of excess motor tones, migraine and anxi-
eity, these are secondary.
2. Methods are eseentially the mioroanalytie system of
(1,
standard inhalation methods andLa_vcreatile� polygraph. lame
appropriate, psychological-tests es well_ aapsychiatrie interviews weld
be used.
The beic facility is a-Very active psychietric service apeotal
tiling in acute illneteesp.tegether-with the_eterfand realities of a general
hospital.
3. Basic exploration -should hot require over 6 moths.
4. Budget. --Y0 do not yet have ,a breakdown on the Siggaard Ander-
sen apparatus, but this ahould-be-available in a few weeks and will be sent
in as a supplement. total cost of apparatus is here estimated as 02 500.-
Personnel: - Psychiatrist $ 2-1000(1/3 time)
Technioian 1,500
Apparatus 21500
MisoeUanooiaiiI
and Overhead 500
$ 6,500
5� Qualifications.
general hospital with en active 24-bed psychiatric service.
-
a a large,
Extensive
laboratory and consultative facilities are available. The Hospital 18 Ln-
corporatod as anon,profit organisation and is tax-exempt. qualifications
of the Project Direotor and psychistrlst are indicated below,
6. With the exosption-or preliminarY olinida_oboervations on
the treatment of nigrainei- there-have-been no:stadies.bearing-dirootly7oh-7
the ,abject of WA proposal..
Psychiatri
3loiclgrant fnon th
ifically for .study of treatment feasibility of
classical SiA0 with carbogen The present reqiest Ls for basic work,
V
44
=6=
and overlap with the clinical study is minimal.
9. h rather interesting application of this study ht be in
the field of personality eTaleation. Since there are certain psychegi-
cal variables, each as-areciety, which-relate-to-the Geld...bass egailibrium,
' it is just possible that=the new and style nothed of aoid,base study would
apply here. Possibly, -the ability of an indiVidual to withstand marIced a id= -
base changes without development ofidisahling symptoms or-other-physical
changes would te-an index of psychological stability.? The induction of acid..Ii
base choices, through hyperventilation, coald be a kind_of stress test. With
the -apparatus which is proposed, the -extent of acibase--change�coald bdo
termined readily.
The Lancet � Saturday I4MayI 6o
TILE ACID-B, E METABOLISM
A KEW I