MEDICAL AND BIOLOGICAL INFORMATION FROM NAUKA I ZHIZN, 1951

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Collection: 
Document Number (FOIA) /ESDN (CREST): 
CIA-RDP82-00039R000200100035-1
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RIPPUB
Original Classification: 
R
Document Page Count: 
58
Document Creation Date: 
December 22, 2016
Document Release Date: 
May 8, 2012
Sequence Number: 
35
Case Number: 
Publication Date: 
August 6, 1952
Content Type: 
REPORT
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PDF icon CIA-RDP82-00039R000200100035-1.pdf35.81 MB
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Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Med~.ca1 and Biab0 ica1 Imo t3 on Pram "Nauka N 4, pp g~12 t III No 2, pp 2$-29; o ? item at bott aka I Zhi xn , Vo1~ XV ~, 3436; No -~, N , of page 23~ N?. No 6, pp~19=21; P 3p~- a O' ~pand Nv 10, pp~l~,3' % Pp Declassified in Part - Sanitized Coy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 STAT Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 KAF AVAI VO .aOVKHOZ Pro:f'essor A.A. Kudryavtsev A. V? Kuz ' michev To take ,acts from life, to make eneralizatic-n$ fora thorn i, ox" thse genere,lizatis ,to actively influence na~ and on tl1c bas in the necessary direction ... such is the method tore, to cllannel it off work off Soviet bioio,istS 'o1lotiTin; .the path L~howrt them by the great Russian scholar, Ivan Vladirriirovi.ch l11ichurin. 1iflling the of this highly gifted tr'ansf'ormer of nature, senior zootech- legacy na.c the Karava evo Sovltoz in Kostrom Oblast, St~;rtislav Ivanovich a..n at Lh ~' . _.yrnan, Hero of ;3ocia1ist Labor, Stalin Prize winner, macic outstand~ 5htc, ili; achievements. Cane :Call evena.nin 1931 a shepherd. at Karayevo Sovkhoz told ZootcchnacS hte man that a pregnant COW had left the milk a.rn ~~.~.~ Sr ~' herd when they hey were out to pasture She was .found in a , pc e thicket after eight days healthy, str'on; calf was running about beside her. . A 5.1. ~' Shte~ man gave hia attention to the unusual occurrence of the calvinof a cow in the cold. Previously, the Sovkhoz cows had in warm buildings. And stir., despite careful nursing, the calved only been sick and many newly born calves had died. cogs had :frequently A:ftet occurrence S?I. Shteyman decided that the methods ~. t11a .5 vkhoZ for handiin, calving cows were unsatisfactory: adopted in the so Oc. , . of, they cause them to be short-lived, to be they make the , cf,r s and redisposed to 'sickneSS. To harden the organisri of the .flabby p cattle he px ryoposed that t'a~v,b.a.tia?-the calves in unheated buildings and that they be given no assistance in birth except in STAT Declassified in Part - Sanitized Copy Approved for Release 2012/05/08: CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Cash oi' obvious necessity. The widespread practice in West ~iurope of making cattle soft aLec1, the h of disease among them. In con~~ciction with to high g,h a,nc~.dence this, bourgcais t1scho1arsU hc,d worked out a stupid theory on the una~ va caseS as tubercnlosi$ and 1ruCeiiosis a.n highly ~,daba~.a.~y o~ such d' ~.s productive ?t rid of theses diseases it was proposed ~r productive herds. To ~ o the product1v1ty Of the herd be reduced. The Soviet ~c,otscn.na,cian an vi gorausly opposed such ~ttheoric:s". The cattle ]bust be 5.1.?. S htaym. ~a to the cold, their viability must be increased Mw such was hardened his new rule. cwbOVf cattle, emerging from the plus 33 to 39 degree tempera' al ture wath ~, the mother into a low temperature ,ure (to minus ' 10 .~.n the body a.~ d. red to work out' a corresponding reaction in response c~;z ces p7, were .Cos to this temperature change. The thresholds of reaction by the bodies emperature oha ni~ of these cattle w'e ^e-'.h ghethan those i.n cattle 4 z~ at outside tempera- Mures of 1, to 20 deg t.,rees. And the higher the reaction of the body, the ~. the viabiJ,ity othe animal. ;interpiaying with the var1OUS ex- ~,reatcr al factors, it became stronger, more adapted. In addition, as tern practice giving birth to calves in unheated buildings exerted ~.ce showed, a-cositive effect an heir off spring, too, All of these facts were new proof of the proposition that the life 1. its development are inseparably bound with al " the organism and. env traits acquired by the organism in its life- time are passed on to its offspring. d that in the calf born in the cold all the organs` Life coni ir me tabolisltl in the organism goes on better and, work more perfectly, the me consequently, fodder is used more economically. From this, still ;x, i ' Declassified in Part - Sanitized Copy Aproved for Release 2012/05/08: CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 another irrtportant deduotior?1 wa,s made; that the Food va1uc~ off' the Lodder changes depending on the cireurmstance oi' its use by the Uving organism. Th~a saa7 ration produced varyi,n results; Leeding in heated buiidins led to thc, death of many ealvee, while feedin in unheated buildings caused great viability in the calves and led to an increase in their wei'ht, to better development of all their organs and to the h ihest productivity of the aninmis Previously, calves at Karavayeva Sovkhoz had been fed !~c 0 and more kilograms of whole milk and, more than 1, 000 kilo rams of skirnrried milk. Desraite this, there was a considerable 1osc; o:~ calves. This happened because the calves were kept in heated buildings where the temperature, as a rule, fluctuated and the air was moist and contami- nated with ammonia fumes, Such conditions did' riot increase but reduced the viability of the organism. After this, when they began to calve the cows in unheated buildings the results changed sharply. They put the calves in separate' stalls with plenty of straw bedding. Thanks to this, the temperature of the air in the stalls in winter was usually considerably higher than it was out of doors. The milk ration norm i'or calves who had been born in unheated bui1dins was reduced con- siderably. For the winter the calves received an average of 100 kilograms of whole and 1, X00 to 1, 800 kilograms of skimmed milk. As a result, cases of death of calves were wiped out completely on the farm and their gro~rth and development improved. Along with this the savkhoz got the chance to economize annually on a large amount of fodder and fuel. Less workers were. needed to care for the calves. The herd at Karavayevo Sovkhoz is being improved in many ways. These improvements include the following. plentiful and rich feeding of the animals, painstaking; care of them, hardening the organism of Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 ?Y1e ana,nla~.s acarresparl~~.r~~ ta thca.r pcra~cad ai' the ~acalves, prapc~ ~tisc a~' ~ c1ec?t~.ve b~^~eda.nin order to a~a?L~a.r~ ~.~M prad.~ata.v~.ty, anal, ~ +, a.na~~.y, ~ sirab:Le o :Ccpx'inl. es x~~~~'~ l~osto~"tsev, way"1~~~1 out Candidate a!~` ~ra.cu~.turia. Sca.e?c , .,, a.r~~,s in thc~ Icar~~vay'eva .11x1^~l ~ru~.cl~ indexes ,dexcs a~' ~~rad1.~c~?ta.va.l,y or x.00 arl year It ~~xmraed out that the ~anan~a~.s wc,r~~ i~aarn at tae same: time of / ,, crew b~~'t'Ge~^ tlaar~ ~r,~~osc earn in the al~r(lr~'x laaxn Ln the w~.nter months ~,,~' n in the winter we .shed at the time of their ~;ati~a~s ti7h1ch hs,~a, been bar Eararn5 more than those ~,rh1ch had been barn in ' the winter gave 26 ~ id.lazixams rnax?r rui.k at their surrlricx? Cows barn in . ~,P born in ?G11e sti~m~rle;r. 'Jha.~.c the pa^adlr,ct~.v~.ty s~,rs't la,c~ta?La.an than those r amounted to 39i kilogxa,ms or three laces of cows born in the ,~v,mtr~~ ,r dm araounted to 3.76 to 3.81 percent, tations and fat content of the rn1.lk the verae pradl.~ct. ,,t~ o~ ~ 1;,.nter cows was b, COQ k~,laarams and ?f~ahe 'a.~.va. i'at Conte b of the milk 3,7 to 3?S perCCnt? ~'at].lnr~s, N.F. n~ostovtsov ostab" Ialc:t.n~; an ~;~~, uop,~;y of several ~ heci that animals born in the winter weighed 12 p c;r c en't more , the hide x.,1.5 laver 8.3 percent more, the heart weighed 19.3 percent more, the ~r percent mom and the kidneys 38 i~a~"cant rnati^e pG~"cr~n~L more, the lun~,~,~a 3 7 1 than those o C summer cows at the ll~U noon Instatute o~ ILX- rho physiological laboratory' v cl.ic:~ne doing res~;ax'ch can the indexes of the perar~enta]. Veterinary lle a and dagesta.ve system, e;~tabl7.shed that the work of t he heart, lungs, and indexes for animals from the Karavdyevo herd :far excelled the same, indexes c,?.C other herds which gave less milks ~ovknaZ has, far nla.ny gears in el~.ccessa~n, been Icaravayevo ,, ~ the milk productava.tY oi' its herds achieving the highest a.ndexes for Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 orner1;T, cows which ? av 3,000 ki1of;rams, o:C mi11 per year for eirht to tcn years were considei very ftn. In all, t1~ey ;av 2L to 30 f~ thousand 1ci1o;rams of milk, ThLs yi,e7d of milk at Karctvayevo has been inoreascd four to five times. Every year there is an increase in the number of cows at the ovkhoz, from wh.tch to farm receives 110,000 kilo raps and recce Of milky Karavayevo iaas etabiished many records Lor the productivity of its cattic b'or example, posiushnits the Second has givon in one year e ov(.r 16,000 kilo ramof milk with a fat content of 3.92 percent' Th hL >her. daily mi1kin;s of incliv'idual cows exceed 60 kiio~ ran's. It is remarkable that the record rows give high yields not only in one lactation bu.t over a period of la to 20 years. Karavayevo managed to solve many. Drob:Lems on which foreign scholars had worked without success o The cows of the Karavayevo herd ive record quantities of milk with a high fat content, a thing which had been considered rnoossibie For example, the widespread ostfrizskaya (All-Union Standard Friesian) breed of bi;-horn cattle is reknowned for its high yields of milk but the fat content of the milk from these cows is only 3 to 3J4 percent. Cows of the Kostror~l breed, whose milk pro.- ductivity far exceeds that of the ostf'rizekiye, have an avera;e fat content of ;3.7 percent in their milk. The fat content of the milk of iindivudual cows at Karavayevo amounts to x,.67 percent with yields of over 10,000 kilograms for 300 days of lactation. In the not-too-?distaxit past it was thought, too, that high milk productivity and fine qu~ity n at Irflast not be combined. Experiments in perfecting cattle of the Kostrom breed refute this conviction as well. Usually the yield of meat frorri the slaughter of cows of special meat breeds was considered go?d if it amounted to L to 6 percent; but ?:`~ ::':.. , ,,; _~ , , f ::. ? . Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 in Karava evo oaws which have been re jeotcd from the milk herd the yield of meat an'ounted to rr~or~ than 60 perc f nt~ Their meat is dis tine:uished by bin highly tasty, tender, art oi' ha.~;h calorie cone tent. 1 With every p ti$sin year there is an inQrease at Karavayevo in tlie number o? cows which give largo cluantitiE;$ of milk distiflgUisht d . by it ?? high fat content, and. thei.r productivity and the period of time a fi .~~ ln~a tr r. i k they can be used by the Larni increases steadi,:1y. At prr~sent individual cows at Karavayevo and its herd as a whole; ho:Lc first place in the WO1ld fo yield of milk and fat content. 3uc1~ are the results of usirrf the I'.ro$~ressive methods o:C caring, for anin~a:Ls, r thods wo:Lked out in ~a the ovkhoz on the basis o:C TiIichurin' S teachin?, rl~he principal activity cif the worlters of the sovlthoz at present is the breeding and pe rfect ion of pedigreed, cattle. lave ry year hung . of calves of the new Kostrom breed are exported to the sovltozes clxeds ones d' the coun~ i7. xn~ch valuable experience has been aamassed and, kolkh in the work of the sovkhoZ workers and. is being; mastered by the cattle of our country. This experience helps them to fiE;ht to ovexM raisers fulfill t1~e Three-Year Plan :Car the development of rniblic cattle raising. The Party and the Government have praised the a chiever,ient s of the workers and specialists at Karavayevo highly. More than 30 workers the sovlthoz have received the important title of Hero of Socialist at achievements in the field of cattle-raisin;. Labor for outstanding Inspired he high praise Of what thee' have accomplished, ' the workers by t z continue their successful labors to perfect the best of the sovkha milk herd in the world. Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 SCIENCE ]N THE KOLKHOZ FIELDS Photo: N. Pasha P. I. Azhirkov, Nero of Socialist Labor, p._( Chairman of Borets K0l.4k10 z, Bronni~Gs ' Rayon Moscow Oblast Much could be wx'j'~ten about how the Borets Ko1kho became a" progressive socialist farm, how we are getting high, stable harvests, how the productivity of public cattle-raising is steaM dily increasing. The history of our kolkhoz clearly reflects the "c c' I k, 1". successes of all oe?\easants. We live and work under Staiiri's Statute for Agricultural Artels; we use our manpower skillfully; we use the newest achievements of agronomic science and technology in our fields. Achieving high yields, the Borets Kolkhoz settles with the j. , government completely in_ib&..own, time; it sets up all the public funds provided for by the Statute; it pays the kolkhoz workers a high daily wage; it invests additional funds in the public economy. The enlarging of our kolkhoz last year opened up new possibilities for increasing the productivity of labor and obtaining high yields. The enlarging of the kolkhoz is enabling us to use the newest technics and the latest achievements of Michurinist science in our fields. Bor?ets has been a steady participant in All-.Union Agricultural Exhibitions. Brigade. Leader N. A. Kastrichkin, squad members A.N. S tnova, K. M. Frolova and 1, received the important title ofl Hero of Socialist Labor in l9Lj.'7 and l9Ii.4 for the outstanding successes t..r_..t: f~:..:.r. 1. ,.. .. ,, o, .. .(' d i r b-r:. : t,. :..,.. r 1.. .. . ,. : ~..~ ~.. .., ...:,, , ,, .ir r. ,. 1...~ . :.. .. ..: .,.~.. ,....,. ~. ,,.....I, ,. I ,I i, r, Y I fr I.. r,..L.: ~ la+I AaM~Y C~,.'u I ,,? I v..:1'r !, . , r x,, t y 111 v 1 `' ?: I .: ; ' r r, r+, ` , r r t e, t~J i': , r "r l I ,p? },4 r ~jp! ~{I~ y~ ) Declassified in Part - Sanitized Copy Approved for Release 2012/05/08: CIA-RDP82-00039R00020010003 5 1 ~~r~ ~,~F~I~~'l~ 11 ij I 'f!: ftL ..ir')r...7 it r , ,r. ~) 1 Q 4.~ ~I 1 ~?~. ) r,: ...... ... ...... .. ........ ... .. .. ... ...... _ ..._ ... .. .. _.... _..... .... ..... .. .... 1 ~ A t r.l .. . ., ., . , ~ ~ r.. o I r~..t, ~ ,k1 i,.i.. Mh~ i Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 of our agricultural artel. More than 2O male and Cernale kolkhoz workers have received goverrnment prizes meda1s" and orders. Photograph of author of article P. I. Ahirkov In l9 'O we obtained high yields on all the lands of the Kolkhoz and not on individual record areas. For exsanpie, in the area of the third field. brigade led by Comrade Mukhin we gathered from each hectare of plowed land 27.3li, centners of rye, 30.90 centners of winter wheat, 26.14 centners of spring wheat, and 28.28 centners of oats. It is characteristic that a good yield was obtained simultaneously in four `crops grown in different fields ender crop rotation With varying preceding crops. The yield gathered by this brigade is not a record one. Another brigade headed by Comrade Zavalov received 31.73 centnere of spring wheat from each hectare. why has the yield at our kolkhoz increased? Most of alJ, because of the elaborate care given the > owings and the introduction of progressive science and technics into the practice of socialist agriculture. The source of kolkhozalth, the basis of its prosperity is the land. The development of all branches of agricultural production depends on the proper use of the land. We place great importance on the methods of using the lands and the system of working them over. All of our lands are plowed under in the fall to a depth of 20 to 22 centimeters by plows with coulters. In many areas, after the harvest-i ing, we plow the stubble under with disc plows for shallow plowing Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 lr1 the spring, after the sowing, we cult:lvat?. Pictures on page 10 of text House o,E' agricultUral caltur e at 3orets Kolkhos Reading room in the kolkho~ library Plowing under winterw ero p fields The introduction off' the field grass drop rotation system has played an important role in improving the use cf kolkhoS land. Since mastered the proper crop rotation by sotiring with perennial 1938 we have grasses. The sowing of mixtures of leguminous and cereal grasses in the fields undergoing crop rotation and the proper rotation of all for creating a very rich soil. Each field in our crops is the basis crop rotation goes through a fallow period and a period in which it , .. r is sown with. pc,rennial grasses. During the fallow period of the hold thc soil i5 cleaned of weeds. The sowing of perennial grasses is the for making the structure of the soil nodular. This the best m as is sown, is an important factor for very rich soil. Experience has shown the advantage off' many sowings of grasses. No less care as required for perennial than for other crops. Manure must be put on the field and nourishment supplied in the form of super phosphate s and Calcium c1~oride. Progressive a ;rotechnics helped the koikhoZ to achieve marked increases in the yield of perennial grasses. The 19I49 sowing of an area of 3 hectares resulted in an w average yield a. 7~ centners of hay per hectare for two harvests. J ~ much attention to the creation of a firm and We are. giving tittle-raising. On the basis of Michurinist stable dodder base for c ified in Part - Sanitized Co Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 s,gxoba0l varieties p~ fodder cxapso r the oy the 1co11chc~~ ~s a,ncxeas~,n~ ~ In ,~,vatan~ 2~ cxppe ? ~6 ~ ~ ~,7~Q we ac~~,ducted e~examents n au~t 4 ~~'~ar ~~l~e mast p~ these came var~.eta.s-1 under local cc~ndq~ ~t~onsp from ~ anew m~.~.~,et~ cow, da~ussa~ 'the south: soy^gh~, Sudan crass, ap i [E ? ~1aevc~ryanen ~ noxtcropsa , such as ~.cusa.ne a,nda.ca ~ s and others. j tested. The. last two e rasa and horse beans were also annuati g good prospects' They gave a plus ~sxenth seemed esp~c:~a~,~.y crops ,. enter dodders for the cattle. The good harvest and a.n taste were b amounted .~ maxantll and horse beans ' ? yield. of green 1arae from a I y more than ISO tons per hectare. r of Meld brass crop ratataon we Along with the antraduc'ta.on ox Tr'ex'tilazer is the read. ti s._7 the use ofertil17~er5 . are ` ancrcan~, as the best' kind o~ ferti~.~.~er. source of a rich harvest. Manure ` out to the field in the wan?ber time i We .take the bulk of the manure. and pale it o s t~.ng it with phosphate e OMton heaps, comp z in lard ~ e or C fertilizers the kolkhoZ asps k. fi ertalazer. Along with th g a large q uant~-~~,~ .~ ?~ o mineral fertal~.Zers an its Melds. .~ ~tpar?tant place is given to seed cultivation smong the ed in our kolkho~~ As you sow, many agrateclanical measures adopt so. All the ;~a,elds ustlY au reap, says our proverb, and j so shall e kolkho~ are sawn with .the.best regaanally distributed varieties. a ~ th we. sort the seeds well, clean them, and careully try' to observe the sowing, norms. ulturalcrops ~.ntroduced Every year new varieties oagxic ~ranomists ..axe tested an o~' Soviet scien~tasts and progressn.ve a G by z were turned into an ,usual labor fields. The fields of our kolkho erne and advanced exper~entatban. ratoz'y of Mich-- sci Declassified in Part - Sanitized Copy Approved for Release 2012/05/08: CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 er crop va.Vleta.e~ o~ s ?eds ~ Wa.thoU'L a doubt, the.. prop sktii;Eu1 waxing over Q~ tY~e soil are the chief factors in getting ~, enough. To be compiete~,y succc)ssIu~. h~.gh yields. But this is n4 - - give cure to the plants, fight against to the crops, : and axia1l.yi we must in our business, we must diseases and pests Which do harm s e c~,a:l~ 1.y not be sate ii gather' ~.ons on tame a per?'orrn all vpexat and ep ang the harvest. The use of these a agr'otec11n1cal measures becarnc possible only ltU1 ? an the basis of ~ra,de-scalp mechanization of socialist agxicu use of h e Txactars, combthes, saes,rvesters, automobiles, t th o~.kha~ workers. easier. Wi f the k ' electricity ha~'e made the work o deepenw fh e provided for lands ne , w ,. the help of the MTS we mastered in of the arable layex, etc.. W~ h ave organiz ed strict control ' n r m of the work of .the txactor drivex 5, We are getting` such. work f t hnics? No small. number. ec e needs of advanced agro 1 the MTa as meets th 1 ;. $OViet eng],neexs and as been designed x ecently by of new machines h ization of various kinds of agr de,igners for the mecl .cultural ~n e machines is a gxea,t help to us in , The use of thes opexata.ons. inc~easing the richness of ...the soil and the yleld? . ~ ~.elds Pram almost all Qur kolkho~ obtained high. and stable ~ gaps. Take -.ManY kolkhoZes in our dis?bra.ct spring g wheat, for expamp . i~ and avoid 'planting it. There was oor crop cansider spring wheat a p ~. ' wheat at our kalkha~ amoun~ad ~ ~. a time when the har vests of spring }But later we learned how to g row it and began to 3 to ~ centnera. gel up to 3n centners per hectare. h results? xt ~is usuaD.y recomn1ended flow did we achieve sic ial xasses. Our results with eat be sawnafter perenn g that...springwh Declassified itized Co is 3 t ~1GS U ?~ .61~14f11ii Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 this we'e poor, But when we tried it after v? a ~ tabus, the yield oi' spr'ing wheat was considerably higher. Spring wheat was sown after potatoes, which were fertilized weJ.l and gave a high yield. The area ' a a s well as the whose, field, was plowed in the fall, to a depth of 22 to 3 centimeters, In the spring as soon as there was a chance to go into the field) we cul' tivated it and then sowed it? For the spring wheat we used only mineral fertilizers: a half centner of ammonia nitrate and a centner each of superphosphate and calcium chloride for each hectare. We did not use manure because . we had fertilized the field with it Sufficiently in 1949 when sawing the preceding crop. Spring wheat is seriously harmed by the Swedish fly, which appears in the 20ts of May. But the fl harms fly the plants only when they are young. From this we drew the ry conclusion that we must saw the spring wheat earlier so that at the time the fly appears the wheat will have managed to grow and gain strength, Bee ides this, chemist. y can be of great help in com batting the Swedish fly, Last year experiments were conducted at the kolkhoz to dust the spring' wheat with hoxach].ora n, after which the yield increased almost two and a half times. Now dusting will be ompul? sour for protecting the sowing of spring wheat against injury by the Swedish fly. The spring wheat is being sown with a narrow seed i dr ll. The distance between the shares is 9 centimeter s, less than in other drills. As experience has shown narrow seed dolling had greater Declassified in Part - Sanitized Copy Approved for Release 2012/05/08: CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 advantages because the seeds are distributed in the soil evenly, a factor which is especisily important in the case of spring wheat , At present we are sowing one variety of spring wheat ~M "Moskovka" -- which is at this time the only reliable variety of spring wheat, adapted to the' conditions of. our district. But we ?t 43 are sure that in t he near future our s e rams. will find new valuable varieties of spring wheat through hybridization, varieties which can resist diseases and insect pests and which possess good flour'. making and breadbaking qualities. The kolkhoz workers are awaiting ,/ ' with great interest the results of the work of Soviet scho1s 4ca,, r_ 1 ~e l~r~new wheat, a perennial, the yield of which a.Cter one sowing can be gathered for, 2 to 3 years. Thus, combining the achievements of Michurinist agrobiology and the advanced experiw mentation of the kolkhoz workers, the nature of plants can be per- fected without limit and the yield increased Nor does the public stock raising of our kolkhoz lag behind plant cultivation in its manysidedness and productivity. As in plant cultivation, so here too we have built on strictly scientific principles. Our farms have model buildings. The stockyards are equipped with water supply systems, automatic watering equipment, electric lighting. Manure is carried by trucks which travel on rails al., running down he middle of the stockyard. Water is gotten an electric motor. Silos and buildings for storing fodder 'Q. have been built ~o the stockyardd44?he stock are fed ified in Part - Sanitized Co Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 rations pxaecribed by the ko1kho 2ootechnican' The ko1kho2 bagan to impxoVO its breeds of stack at he very Qutset, and today all i' Dora are pedtgreed. Using advanced ockMxaisan improvin the preparation oaf scientific methods o,~ s ~ have increased, the output of our anginal. feeds, from year to year we husbandry. year the amount ol' milk or each fodder cow amounted :G~st kilograms, to '3,L36 pig ' tterin ., was 16 per sow, the amount of waol shorn was 3,300 gams per sheep. Broad possibilities in the development of productive stock- raising are being opened up by the innovators of kolkhoz production. Excellent results have been obtained at our kolkhOZ, by milkrr-ai.d ~ A. A. Kashlcina. She has. been working on our farm for years. Through hers 8 cows have been siren bhenE3d. One o:E them, ttLintkatt, gave 7,76 ka.lagxams of milk last year. On separate days the yield from this cow amounted to 60 liters. Picture on page 11 of text the laboratory cottage is of great help to the kolkhoz workers in, their fight or high yields. Lab worker L. F. Petrova is checking ~ the germination of seeds (at ].Eft), determining their purity (center), n o f the winter wheat sowings (at right) and controlling the condo-t~?o Pictures on page 12 of text Agronomist S.N. SkornyakOV (left) and granarYman G.F. Gusev check the condition of the seeds at the granary. At the House of' Agricultural Culture samples of plants gown Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 the :ie1ds o'. the kolkhoZ in i90 are exhibited. in 5peaka,ng xecLntl to young i jlkmaids, A. A. Kashkina told ~' data and the experience of progressive how she used s cjenta,fic in her work. F'irsi; of all, she set up a strict diet s~ck~ra,a~san~ and and and abundant feeding. The ;t'rar high mil,kwprvduciflg cows ration o.~ include up to ~O ki1,o~;raxns oplants ., feed for each . cow kilo, rams off' silage, 10 kilograms of concen~ with edible xaotsf ?~ ~ traces , and 6 ka. 'logrm as of hay. Chalk and bone rneal are added to . thE; concentrates. A salt lick and automatic water supply are set up in the cow's 'trough. of course, a such au amount of coarse and succulent feeds must not be given to the cows at once. The ration was increased gradually training the organism over a period of three years. by The achievements of innovators of production and advance of the :Fact that the possibilities of Michurathst science are proof increasing the productivity of otock~xa~-sink are inexhaustible. ; The enlarging of the kolkhozes set up candita.ons for the further agriculture. In con junction with this enlar- gement improvement and vernent of new pro gTess by kolkho? production, the party and the Govw errnnent presented us with many responsible tasks. ,vitally important task is to strengthen the bond between science and practice to study the contempoxaxy achievements of Soviet agronomic science and the experience of advance workers and introduce them into.. production.. Our kalkhoz tainin f close ties with the seientific is main ~ 1n5tjtut~.0ns in Moscow and the oblaste research institutes and.. Declassified in Part - Sanitized Copy Approved for Release 2012/05/08: CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 x,~ We ofen have scholars at the kolkho~they give lectures to th? workers and help solve many problems. Professor Pisarev, who d tlMoskovkatt wheat, gave a lecture at the koikhoz club ~.saovexed on"he Agrotechnics o C Spring Grain Crop'. Professor Karpirtskiy T, gave one on soils and fertili~erso Candidates of Ag ioultural Sciences Tyultn, Rodionov: and Pelyaev gave lectures to the active oi the kol the systun of f ertiliZers, the yield of perennial khoz on S, he fight against weds through chemical methods etc. '~ ~, r rdSaea We profited greatly from these lectures. The center of propaganda on agricultural knowledge and wide-scale experimental research work at t3orets Kolkhoz is the Douse of Agr:iculturai Culture. Here there are micro$copes, books on various problems of agriculture and cattle raising, and fi1mosM copeso in both ou, koikhos and others, three year agro-' Since.19~0, zootechnical courses which are not separated from practice have begun to operate. The kolkhoz workers show much interest in these studies. They try to put their learning into practice. Wjth every passing g day the kolkhoz~ workers grow more convirred p .. that only on the basis of the use of the achievements of Soviet science and advanced experimentation can new successes be made in the fight i or a still reater improvement in socialist agriculture. f g -lO ified in Part - Sanitized Co Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 The Development of I. N. Pavlov' s IdQas TND INFLUENCE OF ENVIRONM NT ON NERVE ACTIVITY U ~ A. B ryukav, Carxe pondiflg Member at the Academy of Medical Sc iencC s USSR Dr awing S by i Smol a yaninova The basic featureu of Soviet physiology are nerism and evolution They characterize the orig .na-l- and singular course o! the physlob of the fatherland, the ,founders of which were the ~' s 1 e M. Sechenov and I. P. Paviove They .sch great Russian o1ar, were the ?frt to throw scientific light upon and work out problems -~ of environment on the organiser and an the estab" on the influence lishment of higher nerve activity. 's knowni Darwin at first did not place great inportance As a. on the direct influence of environment on the evolution of organ isms. And only afterwards, in 1867, in one of his letters did he acknowledge it: ~1Ny greatest mistake was the fact that I underes~ the direct influence of environetent an the organism, that txmated its, the influence of climate, food, etc., independently of the influence of natural seiectiono't Lon before Darwin, the outstanding Russian evolutionist, A. Kaverzrtevy lea 'ned to give full value to the role of the effect of environment on t he evolution of the organism. But an especially important discovery along this line was made by 1. N. Sechenov. He introduced into the 1tscientific determinationtt of the organism the influence of the environment, the .unbreakable bond between the development of the organism and external factors, with this he STAT . ?' i. .,, , a'.t' %i , ? Declassified in Part Sanitized Copy Approved for Release 2012/05/08 : CIA RDP82 000398000200100035 1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 opened wide sci,enti is hcrizoris for rsaearch on t he evolution of funetiona in genox'al and the evolution o1 higher nervous activity' in particulate The fundunental prop?sitiofS for this problem, which is still as importanlt in our day wers formulated in an amazingly' clear G~nd profound manner by I. M. Sechenov in 1878. '~Gomparative study of animals", he wrote, '18haws,...that the progress of material organization and life does not go in straight lines but branchea' going off on sidetracks in pees. , Here, on these sidetracks, the influence of the environrrlent in wbich the organism lives on that organism, or, to be more precise, the conditions of its existence, t ells on the organism with particular forceo...External influences are not only necessary for life but are at the s ame time factors c a,pable of altering the material organization and the nature of life courses. o Q.Lvery- where and always life consists of the cooperation of twa factors -? determined but changing organiza,tiorl and the effects of environ-s ment.....A further factor in the successive evolution of the animal organism is, as is known, heredity -- the ability to transfer to onus offspring the changes acquired in the course of an indivi4ual life. is Thus Io M. Sechenov through his teachings on theoneness of environment and the organism. added considerably to and developed Darwin's teachings on adaptation. [Picture on page 19 of text: I. M. Sechenov {ti x 3 ~'' . Declassified in Part - Sanitized Corv Arroved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 to P. Pavlov, even in the vary begir~ning$ of the studies which he developed, pointed to they broad svo~.uba.anary~b~ologica~ basks and more than once emphasized the tia be~-ween his studies and Dax'wini$n. EqreSoing his opiniona on the evolution of higher nerve act P Pavlov proved that the physiological mechanism wactivity, ~ p o ,~ of which the animal adapts ha lse ` to his enwirOr~rent is the help the conditioned ref lex. Jcknowledgingtogether with I. M. Sechenov the fact that certain acquired conditioned reflexes are reinforced by heredity, I. P. Pavlov made the mechani.iia of the adaptation and evolution of the animal organiszn concrete and thi ough this, on his part, added to and developed Darwinism Academician icA M. Bykov, in a report at the joint session of the Academy of Sciences USSR and the `academy of Medical Sciences USSR devoted to problems of the physiological teachings o I. P. Pavlov, noted the f a:Llowt ng in the section called "The Teach- ings of Pavlov on Higher Nerve Activity and the Problems of Ecolog" ical Physiology" "r2}ae teachings of ZA P~ Pavlov radically affec~ ted even the general biological problernus of the evolution of physiological functions. For a long time our outstanding biologists have given his teachings attention and have used his ideas and pro-- jects'n their works" In recent years the study of ecological problems began to acquire a systematic character in conjunction with the research in the laboratories of K. M. Bykov on the problems of metabolism, heat regulation, feeding, etc,, and with the comparative pkirsiologica1 study of higher nerve activity being done by many of the associates. working with me o ified in Part - Sanitized Co Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Our laboratory' which has started reee ch on thf3 comparativs physiolO o conditioned reflexes, is careiu11y studying the xo1e ~' a;" environment in the establishment c higher nerve activity. A use.Cul step in the study w'a$ parallel research on animate which are the slle in organization [speci..alJ but have di 'f erent environ bents. ~S Thus, we experiment on such pairs as hazes and rabbits, wild and , domesticated ducks, hens and partridges, r accaon"doge and dome&4Ca' ; . Expanding on the types of animals studied, we select ted dogs ~ those whose natural surroundings and conditions of 1 XLng are es~ ecialay' typical in their influence on the organism. For this p reason we stud birds of prey, river beavers, etc. rj he ecology of conditioned reflexes proved a difficult sub w ject of research. But even the first results we obtained show how irportant this field of science is for comparative physiology. [Pictures an page 20 of text.] 1. P0 Pavlov [right] The sta.mulus ( ammonia) has different effects on the respiratox7 movements aC the kestrel and, the partridge. The first thing we established is the different effect of staxrxu:L? on different animals or of different kinds of stimuli on the same animal. For ekample ammonia affected the respiratory move- mentu of the partridge and the kestrel in a cornplettely different war. In the kestrel it invariably evoked an obvious depression of res-piratory movements. At the same time the curve for the respiratory is movements of the partridge remained abso ute].y uwnchanged~ This can a Y{ be explained from an ecological point of view. The partridge, Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 sight . Taut the legs ~xe1, a bird relies much upon ~.: uses its a~actc,ry organs 1~a a area '~~ Cr;~Q~19 ? - ~r4 'Gk~~ o~ preY WhiCkl ~a these ar aX S were c ui`te , ensttiV~ ex~ten`~; hence a in h a wtunania. ._,/`.,ereu?G~.nf7 results were obtaa.ned in a study o~ tilncarLd~.'ta,oned xnt a,? ' tLa~a.c bixTds. The ~a1].o~r:~n~ sound ef1~?~r 'a;C the he~r~s o~ wa,1.d ack J a?the' ssme type, were used crack stinu~.~, da~x~en~ ~n f, orra but Wr 4;\ ~t/ v 4P c~ in This t1.e~ s a~nt"h to sp1ah d water a ~,~.n~ (breaking p M a c ~s showed that there was no hc~^'~ re bell ~pera~uen`ta an ~ ? ,ca7. du~ ac ].o The normal heart pu~.satians action to the crackle and the bF~ ~~, t the sound of the crack~.a.r~~; and 171 176 per minute changed to i1.2 a ~~1Zen the water spl~,rhed the number a the sound of the bea.la ,n( at pu u~~e and at the 5~~und of the whas r1.e i :lsa~:tans ra,~ to 2~Q per r~~~.n ~ reached 2O? T wbea't is explained, ev~.darx~t1Y's The qu~.ckenin~ of ' ~~~ e h~:a~? ~ b he fact that the splash a~ water ad the whistle s like the raise ~ e y r ~'aX.~iTl,~l bird of prey, are sound$ which app of the w~.n~s of a swooping onst~.nt~~' coming up against in his the s~timu~.a, which the animal is G liied Sim.iar resu1?tw were obtained recen~lY a.n e xpexaaflents an hares/ was it possible to find a s?timu~ On:l: after many expexinlents y ~ ius ?ve of [produced a steady dsteady ' change in`? wl.ch steadily changed the cux r , Of the. frog. This 5t:irnU1us was the paux:~~g the xespiratary maVern,ent the ~'ragm T~:e connection between such a re~ of water an the head of flex and bura~,~ ,l holding the e breath when div'.ng is obvious . The na~.~a.n~' ~ athe heat 'rate acted the same way in reflex of the xe?tar~ ers when `their heads were put in Cher diving anama7.s (ducks, beau ) a water. At the same tame, in animals for whom the same stimulus was ' ?~; ?~ ,; ,r~ ;If;??~,w a `+ l;;I Declassified in Part -Sanitized Copy Approved for Release 2012J05/08 :CIA-RDP82-000398000200100035 1 I tr v +~ 56 : ~>~ Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 ., the raecoox1) the rosponge way a quickening oi' the hr t rate. From thesca observations we drew to T11owing pz'ix~cip1es. In oorn;parative physiological research the proper e1eeta.on off' stingy ul.i for th~r gstabliehrent off' the conditioned xxeficx is o;C great im" por'tanceo The physical or chemical prop rtie the st~.mu1i do not in t''hernselvcis determine tha nature of the~xeaction to ita The latter depends entirely on the physiological significance of the st unulus The proper selection of the stimulus is detsrmined by the relations between the given animal and its environment. Dept;nding on the ecological peculiarities of the envirorirent, the anirn i for the most part uses different ,('orrns of receptivity in adaptative funrtnns. 'fl1is js confirmed, for example, by the lack of under olfactory stimuli tii'?erentiationf between the partridge and the hen' and the very in-' tense xeacbion to them by the Ice strelo Hence, different ahiral~s, depending on their habitat, for the most pant use certain sense or garis and only secondarily use others. In different animal, these principal sense organs are different: in some, sight, in others, olfactory and auditory etc.,/'l"or example, for the haze the chief se~.og~~-~,.e the auditory, with sight and olfactory , oming seconth [Pictures on page 21 of text: i: left] in studying the unconditioned reflexes of the heart of the teal it was established that stimuli which differ in :Corm but are the same in type evoke a different' number of heart conk tract zonso (right] The reflex which retards the. heart rate comes in-' to piny when water is poured over the frog's head. ified in Part - Sanitized Corv Arroved for Release 2012/05/08 : CIA-RDP82-00039R( Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 :Ltnportant ?~ots WG '4 obtained x'eoent1y in ob$ervattions o wild ducks , crux object was to Lind tho stimuli which would aUect their o1'actor organs, rocordi.ng their reaction~e precise' by ~' means o:l a cup^vo oi' they re 3piXatQZY x'aactiaf5 o Many t uli were I tried. turpentine, pitchy ether, ammonia, andthaxas Hgwevera no reaction was observed and we were all ready to conclude that wild ducks lacked oli:aetory sensitiV1ty. How surprised we were when the use at" rosemary evoked a ?Lstlnct change in the respiratory move- ment&o It turned out, as a zoologist who studied bards explained to us9 that during migration these ducks Teed on grass which has rosemary in ita Here we have touched upon just `-a few of the problems which arose a.n connection with the ecological line of our research. Many o1 them are o C broad, principle significance which is 'outside the realm of comparative physiological research and helps us in many cases to properly organize observations of higher nerve ac- tivity in man. I will cite two instances. We had a patient in whom we could not, because of severe weakening of cortex activity, evoke a conditioned reflex at the sound of a metronome and the flashing of a light bulb. Then we used the odor of perfume as a conditioned t stimulus. Inlusing this idea we became acquainted with the kind of life, tastes, and other habits of the patient before has ilinessm The conditioned reflex under these circumstances was set up very rapidly The second instance is a case in which the contrary was true the establishment of the conditioned reflex in the sick man was 1o Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 almost jmmedl.a lus was ~Lht~ ~.a~btfl a~ a red lightn '~e~'~ The stemu it turned aut that the patient had been a cha`~~~ux bed?xs getting :From this we can draw the 00nc1u3ian that in obaexvati011$ a:~ h .;v wa ~,ust take into cor~sa~derat~.0~higher nerve ac4,~~.ty' in man ~ ` the social (fax mans) ooxxssp01 the G441AgiCal (for 3n~na1S) and Bence oC the cond tirnvl.:i, and the cond'itiax~cd xes,ct:~ons. ~.~?~ ~.o~ned s be used as a conditioned ;;ti.muJ.Us ax this sense, a word, which can a condit acquiX'es altogether special meaning for a ~.oned reflex, pexsano 1 ~ c al line oC stud' in pY~rsialc~g', sgmmyng '~'huS y the e CO.~o~r ,a. I. P. Pavlov, 1nr~.11 be ai' great from the coy^e a:C the teachings o~ a.m partance for pxactic J- medicine, too. 11 ified in Part - Sanitized Co Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 N!W OF?~.,SC.~ AND TECHNOLOGY NEW MEDICINALS M. A. Zhukov sky Until recently, plants furnished the prtncipal source of medicinal substances. Now, because ofthe development of science generally and especially of chemistry, the medical pro- has a new source of drugs; these drugs do not differ at fession from the vegetable ones, and some are even better. These all drugs are prepared syntheticallY. During the period of existence of the Soviet chemical and phaxmaceut industrY' hundreds of new medicinal pharmaceutical have been synthesized. Even the drugs that were oncsubstances e extracted ~.z from plants indigenous only to hot regions, such as tropical areas, have been synthesized by our chemists. For instance, quinine, an expensive preparation extracted from cinchona bark and imported from abroad, has now been replaced by acridine, a new chemical . product which posesse$ excellent medical properties, is less toxa er. In the same way, hundreds of various medi- cinal , suband is cheap ^tance$ that were once imported from abroad have now , Especially great success has recently been a- been,synthesa.zed. chieved by our scientists in this respect Declassified in Part - Sanitized Corv Arroved for Release 2012/05/08 : CIA-RDP82-00039R000200100035- Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 SHOSTAKOVSK ' S BALSAM The so~called Peruvian balsam extracted from the bari~ f trees growing in the mountains of Central and South America is one of the most widely used balsarnN t modern medical practice, The Peruvian balsam is well known as ~n excellent remedy such cessfully used in surgery, dermatology, and therapeutics. It is also used in the manufacture of cosmetics and in some indus- trial products. During the Great Fatherland War, when the demand for Peruvian Balsam was considerably increased, our chemists were confronted with 'the problem of finding a full-value substitute for that medicinal substance. The task was successfully per- formed by the laboratory of the 'Institute of Organic Chemistry of the USSR Academy of Sciences under the leadership of Stalin prize-winner Professor M. F. Shostalcovsky, In the course of his research work involving vinyl ethers, M. F. Shostakovsky synthesized a new chemical compound. A de- tailed analysis of the properties of this preparation confirmed its high degree of resemblance to the Peruvian balsam, A long series of tests carried out in clinics proved that the balsam synthesized by Professor Shostakovsky dial not differ, so far as its medicinal properties were concerned, from the na- tural Peruvian balsam, and it even had several advantages over the latter, For example, it does not produce any secondary ef- Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 octs it doea not dry upon eacposure to the sir, and it poses?s be ter bacteric dal properties than the Peruvian balsam, h, Shostakovsky's balsam has been widely used in medical praot:tce, AL3O1 IC I An original antibiotic, 'Ialbornlcine, tt has been recently discovered and thoroughly studied by Professor G. F. Gauze, Sta- ui.n prize winner, together with his senior scient1fic coliabora?- tors M. G. Srazhninkova, V. A. Shorine, end S. D. Yudintseff, in the antibiptica laboratory of the USSR Medical Academy. I .Vi t4iy; Despite the fact that the effective treatment of pneu- monia of Young children has been sharply improved .~a and dysentery by the introduction into medical practice of sulfa preparations ~_ (sulf adzene, sulfanilimide, sulfathiazole, etc), as well as ~.a of penicillin, these drugs st iJ.1 do not always produce the de- sired sired results, It is also known that several cases of the so- called 1Isu1fa~resistantt" forms of dysentery and pneumonia have been observed. All this required a persistent search recently for still. more effective medicinal preparations. Albomicine proved to be one such preparation. The new Soviet antibiotic is a powder of whitish color. It dissolves perfectly in water and does not produce any toxic effects when introduced in great quantities into the organism. An important feature of Albomicine which makes it superior to Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 M. Popovsky This new preparation has been tested in the Pediatric In- stitute of the USSR Medical Academy, awarded the Order of the Red Banner of Labor, and has received high praise from the cli-. nits that are headed by Professor. G. N. Speransky, Active Mem- ber of the USSR Medical Academy, and Professor A. I. Dobrokho- tova, Honored Scientist, The effective therapeutic method of blood transfuon has THE BLOOD SUBSTITUTE other antibiotics is its tendanay to remain w;ithT the organism longer, ;for instance, than peniciiiin. A study of its ooneen- trati.on in the blood after a single admtttration proved that Aibormiethe is retained in the body up to 2 or days. The tests on animals demonstrated the complete harmlessness and the remar-? kable curative properties of this ant:ibiot;ic, especially in cases of ila.ness provoked by penicti1in-resistant types of infection. In addition to this, Albomicirit increases the protective proper' ties of the organism. Albomicine is particularly effective for treating pneu- monia in children during the first year of their lives, and for various complications of dysentery, The Pharmocological Commit- tee of the Scientific Council of the Ministry of Public Health has recently approved the widespread use of Albomicine. tjfi :!!I Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 been widely applied in Soviet medical practices Seveml insti~ tutes, hundreds of health stations, thousands of concu1ting rooms throughout the whole country are preparing and conserving blood for the purpose of transfuoing it into wounded and sick men. xn the public health system of our country there` is a special "blood service"_ with many thousands of doctors serving it, as well as an army of donors_ who give their blood. for th:l,s purpose. More than 250,000 transfusions are being administered in the Soviet Union, which is many times mare than in any other country in the world. However, the use of donors' blood presents a series of sub~? stantial drawbacks. The donors' blood is expensive and compara- Lively unstable, and its transportation to distant places in- volves considerable difficulty. But the most important diffi- culty consists in ^the existence' of four different groupings of human blood. Transfusion to a patient of blood of a different type may cause complications. Besides, it is very difficult and sometimes even impossible, to determine a wounded man's blood gouping under battle conditions. Therefore, the idea of devi- sing a substitute for human blood arose long age. For many years, however, all attempts of that sort proved to be unsuccessful. various saline solutions, devised by the scientists, could not be substituted for blood. We know that blood is more than a liquid containing a certain quantity of salts. It feeds the tissues of the body and must, therefore, contain such nutritious substances as sugar and albumin. But the principal defect of all projected substitutes in E~irope and America consisted in the fact that they a;~lr ~~,u~~t'~i r^f!~^eel,r t~1 r:,Yt Jiir F..T ~+.I tll ~M'r: 1!!a i..~tl ti r rt rJ 'iS 4t s~ 1:,^ r f rijl'i'" ! t:.i ri v tL. r'. f .71 .d~1Fed^~ ;. a.. ~h..,..d~,x. ~ frvA.~.,., r r {..r... t?!:a ..51.^ ~.,,. 6.~J~,L,t.~.x...~.~ ..Ss 5,.. .,. o r.,,r ,Er. .. .i .,7 9'ri-..~, . ^ r. ..,.:.:.~. t . ,7.rt. . L a;,1;~ t . a,:%` t s ^:I:~"t 1 ~ t i,'Y q~: n ~ i ^i'~ ~ ~~'Jr~i ~K s'I. ^~'~ ified in Part - Sanitized Cor v Approved for Release 2012/05/08: CIA-RDP82-00039R000200100035 1 t,,, , . . ; h t"''. .`_:;~ `,:,~ J -~' tir'r ~~~~ '., ;. ~'~ ?, i Declassified in Part -Sanitized Copy Approved for Release 2012/05/08 :CIA-RDP82-000398000200100035-1 rnu~ats ~h? forma~~on off' ~~he pa'~;1?n~'s own b~odd,` d~.d not ~ t~ the Qss~b~~~.~y of faxc~.ng thn sick ergan~ wheras,s ~.n .many cased ~ e4~~ u~c~,es wou~.d have ensured h~.s recavery? ~,sm ~o genexa~~ blood p G Bn~?nky~ DAC'~ax of B~.a~.ogy and Pxo- Then, ~.n ~,91.r~, N ? nff ~nsbi~~u'~e of Ch~m~.stry. and Tec'h~ ~'~ssax of the B? x? Monde~.ey h~,s xes?axckl f o~' the purpose of dev~lap~ no~.ogY of Moscaw, b?gan hog.?b;l~' be~`or~ ~~hc~'~ fi~:i,m~ the sc~.enb:i,s~ 3.ng a b~,ood subst~,'~ute? ~ Y een en~ra ec~ a.n 'the ~ursui'~ of _a pure~.y and h~.s col~,eaguos had b ~ g the had been seeking a means of ~,ncxeasing pxactyca~. problem. y ~', ' t of blood :obtained ura.ng th? slaugl~'~er of catt~.e ? 'tkle qu&n~,1 y h s:lau kl'Gex they pumped out abaft h~~.f Once, 21~ hours before t e g ~ a caw. ' U an slaughtering the co~~t, they of the whole b~.nod from p t of this cave's bload had been ent i~^e~.y re-~ found that: ~~he quant_ y Belenk was dee~aly in~exested in the process plen:~shed, N, G, Y f such Large quan'~i~ ~ es of blood by ~ni- of rap:Ld res'~orata.an o ? ~urned 'here occur in the bodies of tes- mass. ~ral.denbly, he ass , much b~.oad some substances wha.ch s'~im-- bed animals wh~,ch had lost ~ nr of blood--forming organs. Tkaese substances, u~.ate the funat~.o n emoact~.nes t' i a e ~ , ~ctZvators ~ in~en~ the sca.ent:t.st named th~,m h ~ ? t'on w~ must be secreted by organs of 5:~f:~ers) of blood forma n. , x~~iall. depxaved of their .bland. wou~.d. an~.rnals that have been. pa y r ne or anism increase the ac'~ivity of floe hernaac't~.nes tal,,en from o g ' ~athar? The answer could be found onJ~y b~.aod-forming organs ~.n a by Lost. A servant braugh'~ some rabbi'rs into the i,aborat~ry; from a r ? , . ~ .. , , .. ,.. , ~ ..~ ~~ , L ~ .~ I ... ,. ... .. 1 . I :.. ,., !,. ,, 1 r , ,., . ~ ., t ,.,,.. eS ,C..f 3.. ?4 ,., .,. ~ . I.. t, ..I s, ~..,.,_L. ...:........... .P.,,.r__,.,,n.:_ ,,,,. .,b.._,_ ,,..~, a.. P.,i,_.. 1 r. ~r ,.~, a.'. I. a. , ,-~41~A~ f~, , :;~ 7i..r.,;.r r{..,. .r.'nl;. 1, I,:r'n?, :.>,/~? ..,.. ..,, ......t .;, ~ i.:a i l,l,d ,~ J~r.t:` LI~,i,~,~f ..,,2iN{~4~&~h~ i ..,. ;.' i (. i,. ,.,;?. ~ Yn ,. n, ,, f a. .. a ..,,;r, r. ..,. 4 . . .. ~ - 1 i ,'.f ~ { i n r.'~.i j '~~ r I I I :' f A {4. b, ,,., , ,r .:.... vP{ `?%~~~~~":, , I~ h'rf. f, r, a, f~,~ ' ' ~ ,~;,,~ I ; 4 s:~ ,~`' ,,a :- ' ~~ Declassified in Part -Sanitized Copy Approved for Release 2012/05/08 :CIA-RDP82 000398000200100035 1 .,...'~;,._; , ._ ~, ,.,,,, r ? ,,;, ~ ~ 4 , ~;~ ~ , , r ,; ,~ ,,: f ,,~, ?. ~f4d :~, .~,II..(.. L. ,i. ~, t. ._,, ., d,l i_ 7.. ~~..r ,.).,... ~._.,...~. ~. 5, .,....... ... ..... _. _. __. .. ... ... ... ._.___ ............_.. .._.... ....._.. ...._._ ......... ._._... ... _ .r ,,., _.._ _... ~,,.,. .,, .. ,,.,. 4. .. rn .. ,1 I+ ., _...,..~, C~G...fr~'{I~ Declassified in Part -Sanitized Copy Approved for Release 2012/05/08 :CIA-RDP82-000398000200100035-1 'tk~ese, pant of the b~.oAd hid l~apn ~1~?v~,?us~.'Y arsmoved, Sams of the xabb~.ts wQx~o ~.h,~ ~c~ted w~~h s sma~.~. c~u~nt;~~ty of ~'hsmAa~'~~Va~tc~d~~ aaw ~ s b~.oAC~, ox, maxs pxec~.s?~.y, t1~~y r~ce~.ysd ~.~~ ~.~c~u~d parts t~.an ~~ b~,oad serum, O~t~er an~.ma~.s: rscea,ved no ina eo~t~,ons, ~a~ su~.'~a~ canf~,rmad the ~c~an~~,s~'s ~ssti~mp~~an~' 'the a~~.ma~,s ~hs~ had bc~?h givon the serum xes~vz~ed 'thr~~,x~ vx~.gina~. quant~.'ty off' b~.ood tw~.re as quic~c~.y as 'those that hsd no't been submitted 'ta that procedure, Lvery time these tests ha~ra besn repeated, t~Qy have in~r~riab~,y g~,ven the same resu~,ts s 'the serum ~,ncreased the activity of b~.ood~forming orgnns and considerab~,y i.mprovecl, the state of anim~~. ~ s hea~.th, Pro~'essor Be~.enky perfected hi.s d~,sao~'ei~y duxa.n~; 'the 'third year. of the G;teat T'ather~.and 'Nat, Thousands of wounded so~.d:ters needed b~.oad 'trax~fusions, The b~.ood was conveyed to the fi~k~ting front from the disten~~ rear, trans~or~ted by s~aec:lal cars and airpJ.anes. ~u~t the donors ~ b~.aod mere~.y rep~.aced 'the b~.ood ~.ost by the sicJ~, and wounded men w~.'thaut stimu~.a'ting the ~~,ood~generating procesass w:i'thin 'heir bathes, Nfeanwhi~.e, many o:~ ~Ghese men were su~`fering :from the s~.uggish c~ct ivity of their b~.ood-farming organs, N, G, Be~,enky had a m?ira,cu~,aus remedy in 1~~.s ,hands, Some grams. off' his serum increased 'the. b~,ood-~fnrm~.ng ac'tiv~.t f a~' rab~ bits and dogs. Ha~v goed it ' wou~.d be to ut~~.i~e this remedy far the he~.p oi' men : I~owever, anima. b~,aod e~nnot be transi'ueed ~,nto man; as a rule it produces a de~rastati~~ act3,on in his argan~.sm, "Prhy is huzr-an b~.oad incampatib~.e wa.th ana.mal, b~,ood7 Declassified in Part -Sanitized Copy Approved for Release 2012/05/08 :CIA-RDP82-000398000200100035-1 ~~ hid a~rer~dy bs~n astab~.~.slzad ~.r~ng ego that tha p~.a;~ms,: ~h~a xine~. ~~ mays o~ b~.aod, was d~.~'~ex~sn~ fox packs composing 1~ 1~ bind o~ an~.ma~.. Tkae~~ d~,~,~expnepa axe avpn obsp~u'pd among xe~a~ s,tive~ ?~' ~k~p same ~ppcies, The ~l.msma o~ one an~,ma~, bey resent ama oa.svnous when. x,n~ ec~~~d ~.n ~ g:~van c~uant.~ty ~,nto anathpx o s p But '~ha.s ;I.s anl.y one r~mson against thv ...use a~' an~.mal. animal. fox ~rans~'usions~ .The other xer~son consists off' 'the fact bhaad that while: ma.xting d~~;~erent' groups ~f bl.aod, the bl.aod corpus- cl.es a frl.utinate, sink, atxd be~.ng no more able to sure 'L?he ax- g ganism, prevent the 'tissues From recea.ving oxygen. I~ow could we ~minate the resul.'te or plasma heterogeneity when. in,jec'~in~ ani~ e~ . a blood into min? Th? scientist was deeply concerned with ~h~s m ~. uesta.on. He was ~'irml.~y conv~.nced o:~ 'the pvssibil.it f o~ discov~- g, erin a miracul.aus substance 'that wou~.d substitute fox human g blood and at the same time waul.d serge as an intensifie~? o~ the blood-f orm~.ng process a The Saviet scien~t fists :faced an ex'txem~~.y difficul.'t pro- bl.em: it was necessa~~y to ~,evel.op the.. serum in sucka a way that, wk~ile bein relnov'ed n:f all, pz?aper~~.e~ dangerous ~;o man, ~.t shou~.d g not at the same time be depraved o:f its capacity o~ increasing blood-~`oxmin activity in a sick man's ,body.:. Al.l. this demanded a g teat deal. o:~ e~~ort, .energy, and devotion. Only after innurner~ g able tests did the indefatigable researcher and hip assistants finally achieve the desired resul:t~ The dad' came when a routine control. test with dogs showed .. ,, d .. ; , ~ , .,., . a,, ,,,, ~ ,, , " , ~ ," y F ?,, ,4 ., .I.,, , ,, r.~~. r:. ~, .,.,i ,.l ,..: r ,..v .. .... .. .....y 6.d...:.. ,i ,...,....,. _~., . ,,. .. ~i .. .....,, .,..4.. i,...... ?i. ~, r. a'i;: r,'. ~'. a h. i ,f-~,' ~ ;ti t'`radn, 1 I ~7tii1,, it, ~ f` .':~,,. .4 is, ;..r,: i ,.1 s ~ n';~ i i rz?" o ~;IS. .. .. ~..-, ? , ,. ..~,:. ........:.: ... ...:.o ". ' , . , .. ~ i xl: "~ ~ a ~ ~ i ,,,a+,i ~,.~.~, i,~fi'~~~,, ;,;; ~;"",a, ;,~~?{~~,r,`c ' r'~ ~ ,,~;',,,,^;,,,' ~I~,, ,,.:,;",",,' `; Declassified in Part-Sanitized Copy Approved for Release 2012J05/08 :CIA-RDP82-000398000200100035 1 ,, ,,,; ~ ,y , .,,,; ~,,,, ~,j' ' !~.` ,. n ~ ~,n;=~~Jra Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 essaxy to prGv?nt trauma as well as the caagu1atian of b1ood nac- ~ which a1wm~s 'fakes place after a burnM P?xmexly, ~ sa1ine sa1u- t hysio1o ica'~ so~.utiQ~a, was usua~.~.y app;~ied ;~an, or the so~.c,a~.~ed p g solution does not contr in any a1bwnif, :1,n suc11 cases. But 'this which is $o necessary ion'an organism strug~1irAg ~'or his 1ife Be1en1cy's serum contains Lt however, and Professor Arapof, there- , The patient received 4 liters of f ire, courageAUS~.y applied ' ~.ed of shock ended, the blood received the new preparation. The state it normal thickness. It was then possib1a to begin txeatment. skin had been transplanted to the burnt After the first strips of surface, the patient received another injection of Le1enky's pre- partition The strips began quickly to head. and to assimilate. strips beg In 3 months the patient ent left the clinic an absolutely healthy man. A great deal of such 1 masterly and daring `tests with the serum have been conducted by Professor Arapoff and his colleaguea. Besides Sk 'r ' institute, th:>_s serum of non..specific graup- `~?r ~,1fasovl}y~ ing has been tested in the Central Traumatol.ogics~. and Orthopedic Institute, in the C. Potkine Hospital, and in many other medi- cad. Leningrad, Briansk, and Minsk? More than x,0,000 institutions of hen:t, transfusions of the animal serum have been administered by doc- tors to patient S . ~fex~ng from various disturbances. The ability' s lz.~~. . of the serum to raise blood pressure in the vessels and to in- crease the act,,,ty of blaod-forming.. organs made it an indispen- ~.vi sable medication at the bedside of every wounded man in need. of blood. Belenky s preparation quickly healed such serious ill- nesses Also, to the men who could not take any nesses as dyspeps~. -l0 Declassified in Part -Sanitized Copy Approved for Release 2012/05/08: CIA-RDP82-00039R 000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Tood because of esophagus affection, it completely rep1ae~d an albumin diet during a few weeks. In short, the serum of non.- specific grouping discovered by Professor N. G, Belenky proved to be a perfect substitute for the liquid part of the blood, a medical propara'tion to which the surgery of all countries in the world have been looking forward. Cheap, and at the same time possessing extremely valuable qualities, this preparation is now receiving an ever.-growing application in the therapeutic prac- tice of our medical institutions, It is going to be a mass rae.- dicinal remedy. The discovery of non-specific serum is a remarkable vic- tory of the Soviet biology which fo11ws the way carved by I. V. Mitchurin and I. P. Pavlov, For the discovery and clinical tests of this serum, the scientistinnovators have been honored with the Stalin prize, END 11 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 ^1 _1j= J t ~ A SUBSTITUTE FOR BLOOD M. Popovsk'iy The transfusion of blood M this an effective healing method widely used by Soviet medicine, several institutes, hundx^ed$ of stations, thousands of special oi'ficss throughout the country pre- pare, preserve, and give transfUsions o;E blood to the wounded and sick. There is a special "blood corps" in the public health system of the country with tens of thousands of doctors and an army of vo1unteera who are giving their blood for transfusionso. More than 2S0,000 blood transfusions are performed each yeax in the Soviet Union, many times more than in any other country in the world. However, the use of blood from donors has many ` basic short'' comings. Blood from donors is expensive, it spoils comparatively quickly, there are considerable difficulties involved in sending it long distances. The main difficulty dies in the fact there are four different human blood 'groupsm Transfusion of blood to a sick person from a group unlike his can lead to complications. In addition, it is very hard and sometimes i.mposible under conditions in t he fie id, to determine the blood group of a wounded person. Therefore, long ago the idea of creating a substitute far human blood arose. For many years all such attenps ended in failure. The various salt solutions developed by the scientists could not re.. place blood. But then blood is not simply a liquid with a certain amount of salts in it. It feeds the tissues of the boar and should, therefore) contain nutritive substance: sugar and 'proteins. _ But the chief shortcoming of all substitutes proposed in Europe and Declassified in Part - Sanitized Copy Approved for Release 2012/05/08: CIA-RDP82-00039R000200100035-1 STAT Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 was tha fact that they cuid not oaue the building off' and ieric a the sick person s on blood Ix', maxi' cans the change o making the sink body build blood cells would have gua?afteed its reoovery. In 191.2 N. 0. Be1s3n~ kiya doo'bor o biological sciences acid professor at the Moscow lnatLttitite ;Lmuni the search for a substitute for blood. Not D. Io Mendeleyev, joinad ienbist and his associates had been busy with long before this the sc a purely practical problem. they were looking far the possibility of a.ncreasifl?; the amount of blood obtained during the slaughter of big hort1 cattle. Once, twenty four hours before the slaughter of a cowi they pumped about half of all her blood out. In twenty~1'our kio~irs the amount of blood in the body had been completely replacedo The rapidity with which animals replace such large quantities of blood deeply interested N. G. Belem kiy. Evidently, he proposed, in the body of animals which are being experimented upon and have lost a great deal of blood, some kind of agents which increase the , activity of the blood making organs appear. `these agents ,.W the scientist called them tthemoact:Ln5't, which means activators (intensim f , ier ,1 of blood-'making should be secreted by the organisms o C anlmals which have had part of their blood refoved. W111 hemoactirLs taken from one organism increase the blood-making activity in the organs of another? Only expermsntation could tell. The assistant brought to the laboratory several rabbits from whom a portion of the blood had been removedn Some of them were in- jected with a few ''hemoactin&' from the blood of cows, or, to be more exact, the liquid.part of the blood -~ the serum. Others were not injected. The results confirmed the scientistIS hypothesise Li Declassified in Part - Sanitized Copy Approved for Release 2012/05/08: CIA RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 animals which had been injected with the serwn the Tx uer amouxit o:L' blood was replaced twice as ?ast as it was in those whioh had not been injected. No matter how mark tunes tha experiment was repeated, the results were invax ab the same: the serum spaeded up the activity of the bloodMpxoducing organs and considerably unproved the state of health off' the an;1ma1s. The Great Fatherland War was in its third year when Proessox Belem kiy made his discovery,' Thousands of wounded so1diexs needed blood transfusions. Blood was brought from the rear, special rail- road cars and airplanes were making the deliveries. But the don- orst blood, transfused into the blood vessels oC the sick and wound ed who had lost blood, did not cause their blood to be re-'made. In addition, many people were sul'f ering from insufficient activity on the part of the blood-making organs N. G, Belen'kiy had a wonder-'working agent in his panda. Several grins of his serum increased' blood-making activity in rab- bits and dogs. How wonderful it would be to use this agent to help people however, the blood of an a haa1 cannot be transfused to a human being: as a rule, it produces a destructive reaction in his body0 lhy cantt the blood of animal and a person mix? It had long ago been established that protein, which corn- prises the basic masso1 the blood, is different for each species of animal. rl'his difference is observed even within the same species The protein of some animals, injected in a known quantity into the organism of others, proves toxic, But this is only one reason hinder- ?? ing the use of animal blood in trans\asion. Another came is the ? '; . . 'd 4. Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035 1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 fact that when di4x~nt blavd ouP m~xac~ tk~s blood cp ~~' the dale v~ sox~n~ : , and,incap uncles s,gg~,ut;r.n4.~o, P . t~a5US Withot p~~1'~,~n? ra,sm a1an~ex J ies.~ the u1d the consac~uenc~s aC the diarenceS in the hype How ca the b~.aod o~ a,nra:~s eiaajhated in trans o~ the ~,,buzr~en be ' enta.st deeply, ~ die s? r~hjs idea agita'~ed the sea. to hu~na.n~ being irm c~~aat~~ a wandexu~ ardent .. .. ~~.,y believed in the posw3bi1Y o tttitte or human. b~,aad and serve ~Ll~.d at thes ar~1e time ;subs. Wha,ch to speed UP b100 akiflg th a campla,ca'Ged pxoblEno Te Soviet ca.Entt eras aced w~ h --.._ lArnU1d. lose all the proper" eng ~ ener~Y,,~st his aa~~istants acha.evC the des ~~h,~;' tireless sc~,cnt~.st end h' ~ di , ac check ors da~~ shared that C e a d&;~ when the custom Y T same retain the ability of ick orgafisra. Much 1abax9 the needed for k,his a and. th was ' raising the oadMrnaking acti~' taes harmful to human beings but at the . It result. m ~~'akd ib i [PJ {{ 1 4~ ~ ~i i ~r ! ~ I ~ ~ t f ~I 11 ~r r rr r~ +' ,sr ~ { t,i i ~ ~~ 1r here gun was a.n~ccted no h~7~1~1 xe hen a speC?,a11y developed blood sex w td ~ea the fact that the ~ . ,were observed. Numerous cl~~eck co su1~s aerlvn obtained was , innoauoua for any axraamai? itu a,ct~.an on. a human be~-flp The thing to do was to checlc , crcaus exlaexaa~~en~ arl hamsel1 G 'Belem kiY decided to d0 this dank 1V. n ted himself with x.00 cubic he resence Of his assaca.a,the ~.njac In t p ~met~er;a of the serum wha.ch he had deveiopad. The s ame... amolmt o~ cent led to his nan.pracdssed blood injected into a human being invariablY sect on the argan.ism of new repax'ati0l had na harmful e de ath . The p the .SCient],Sto of Only after mark expel' efl5 Declassified in Part Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 In px'dcx to hand kliy disoove avex to Soviet duotoxC~ com p is 1u~~-ary pxQpe~`t~,e3 in the Light ~.eta~.y~ he had to 1ai~ ~ fox the ~xsan. he dixectnx cL the surgical clinic . ~,a~a o~ ~ sack p~ at the Institute ;i"meI~i Skli ca~rskiy'' FraLessc~~c I ~ A , 'appv, dc~x' ~'o~ took k the 'bask this ~~'1.auS 4X~x;lY1~'~. His e7~p4~~i~ll~nt~ o~ conducting , were no lees da~:ing then thc~,e p ~ Qxfarznad' by the disaov'exex ~aL the .'~ serwlt. D a , Axa,pov bcl~. 1;eVed in the preparation and gave txarts^ ~ it to peoplo wa. ' th diffexcnt blood gxaupS ? When nacessar'y ~'us~.ans of a. e~ the sxum was liven to patient,s in vcrJ large doses .~. up to three" s f if tkls of a liter at one tran8f.us10n. o$t benefiairta. effect in cases of burns. The. serum had its m Qncc , ~n~~ covering a,]mos't ha,' af' his akin an electrician ~~~.th burns The doctors feared gn'eat1Y' fox his life. was brought to the clinic a Above all, they had to combat shock; and coagulation of blaoda which Previously a salt or sowcal1ed physio- always occurs aster bLwns. logical solution ?an had been used for this. But such a solution did not conta,:i.n protein, is so necessax'' to the organism _i'a.ghta.ng protein, which ' ~.ch . for its life. Helen kiyy' a serum cantax ns protein and Profe$SOr Arapov used The patient was given ;Gout litexe of the new it unstintingly. preparation. The con ditton of shack changed. The blood took on its noxma . TheJ' y could now get on with the heaJ.ing. ~. thickness When the fast ,skin.. grafts were made onto the burned axea the patient preparation. The grafts soon began again given Bele~~ was again 'k'Y' grow. In three: months the patient left the clinic completely re~ covered. No small number of these daring and expert experiments in the use of the serum were made by Professor Arapov and his associate. - In a dditi.on to the lnstitUte izneni Skli f o$ovskiffY, the Central , Institute tOlOgy and Orthopedics, the hospitaJ. imeni _ of ~r auma Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 5, ? Botkixi, mark hos~aita1s in Deainrad, Bransk, and I4insk toted this ec~rum which is not limited in Lts use to a sirngle species. Doetor-~ gave more than 10,000 transut'sions cif aninf.al aeI'um to patien't% suffe 'ing f rOm various dieoxders. The ability of the txans:eused serum to raise the blood pressure and to increase the activity of the blood"ziaaking organs made it an indispensable agent at the bedside of the patient who had lost blood. Belen'kiy~N prep' arati.on rapidly cured such serious chi1dren's diseases as dyspepsia. lnpeop1e who could not take nourishment because oI some injury` to the esophagus it completely replaced protein feeding in the courrv of a few weeks. In brief, Professor N. G. Deienkiy's sexwn, non-i specific toJ species, turned out to be a full value substitute for the liquid part oi' the blood, a preparation which surgeons all over the world had dreamed of Inexpensive and at the same time extremely valuable for its properties, the preparation is now being introduced more and more widely in practice by medical institutions. It has to become a mas$ scale medical preparation. The discovery of a serum which is non-specific as to species is a wonderful victory on the part of Soviet biological science, following the trail blazed by I. V. Michurin and I. P. Pavlov. For the discovery and clinical testing of the nons?specif icw to species serum, scientist innovator N. G. Belen' kiy and D. A. Arapov were ararded the Stalin Prize; o Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 'j NSW VITAMINS FROM PLANTS f, Thid :'orest shxub, the ob1epa ( creepsrJ, has been studied at the Ai1MUnion Scienti;Cic Research Institute Lor Vita? rains. P,esearchers show that its fruit is very rich in vitamins. One hundred grras o.C the raw mass off' berries contains up to 180 ~. V q 1J% ?V%1 1 ?11 milligrams nd 10 milligrams ol V i~ A (carotenof V1.tamin C ~, ) The obiepil ha is widespread in Siberia and the Altay. At present it has been acclimatized in the central zone of the Soviet Union, The berries of the oblepikha, left on the shrub till the first autumn frosts, acquire a pleasant flavor with a faint odor of pineapple. The valuable new vitamin plant is being grotim on a largo scale in Moscow and Lenin oblasts, In addition to the oblepikha, the institute has done research c'. on the vihnin content of varieti s oi'pwnpkin produced in Ros1Ov Oblast at the Riryuchikutsk Experitnerltal Station. One hundred grams of the raw mass of this pumpkin contains up to 20 milligrams of ca- rotene. The Krasnodar Vitamin Combine has mastered the preparation of carotene from the pumpkin. Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 * THE) WAYS OF MECHURIN ~~ P. A. Yesau1ov, Candidate In AgricuJ.tura Sciences Drawings by V. Poznanskiy ProduotiVe stock.?raising is one of the basic branches off' ?' reu1 urei satisfying the needs of the ytpeop1e for important food prod' _t f ucts and supplying the enterprises of food and light industry with raw material. The prewar level of head of productive public stock was achieved in our country in the first years of the postwar Stalin Five?Year Plan. For 19L.8 alone the head of big horn cattle in the kolkhozes increased 23 percent, the head of swine 75 percent, sheep and goats i6 percent', In April 19L4.9 the Council of Ministers USSR and the TsK VKP (b) adopted the Three~.Year Plan for the development of public kolkhoz and sovkhoz productive stock-raising for l9L.9.. 19;1. In this plan the objective of all kinds of development of social stock raising was established as the central objective of the party and State in the development of agriculture. The achievements in the fulfillment of the first postwar Five- Year Plan in the field of stock-raising will ixi the history of sow cialist agriculture as an important victory of the Soviet peopled In 19LG9 and l9 O the head of social stock in the kolkhozes increased at rates which had hitherto been unknown even ip our country. The pre war level of g,..harn cattle was exceeded by L.o percent, of sheep and 'N .. goats 63 percent, of swine L4.9 percent. ,%' Especially great successes in the improvement of stock-raising were made by the kolkhoz peasants of the tlkrainia and Belorussian STAT Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 - px~.av o1a~.as~t~~ ~ha lc?~.1~o~?s a~ (~~k a5~,~;~, and K~axsk, Moscpw anc~ : ~a P~n~~n anc~ '~~nbnv ob~,as~ts, ar~,d ~ha said K~merov ab~.as'ts f,n ~.b?~ ~ ~ ~si.ah repu~~.a.c~ maxked~.y ~.~.ereased the '~~an~cau~as~an and ~,~,dd~.a heeds off' ~.a. k~.nds off' s~toclc. pxeyrax ~.eve~. of the vemen'ts a.n the deva~?opmant off' Ong af' the most :~mpor~tan~ ach~.e n ~ri the ko~.khazos and aovkl~ozes ~S 'the soc~.a~. producta~ve stock?xaa.s~. ~ stwar ~ ea~^ much: work has becn Ilona. im rovement o~ p~d~.gree. zn 'the po 1 P hard. ~'ox 191.~9.~.g~0 a~.ane 'the 1GOl.kho~aes tin ~.mpro~ng 'the quala.ty a,f, ~,he i:1.~.a.an ha.~;h?qua:lw~.tya pedigreed stud ana.~ have been sa~.d aver hal.~ a m , , , o s the moat widespre~.d h~.gha?y produc~Ltive mat. s ~.. bu1.~. s, xa,ms, h ~ ~ breeds in the USSR. . bia~.o ~.ca.L _ science has p7.s~yed an enor~ Progressa.ve Michur~.na.st ~ . ..? on of our s~tockMraisin~~ As is l~nawn, moue role a.n the txans~ormat.>,. lotion o~ organic ,forms in .nature do not ~a~~win~ s teach~.ngs on the evo y : char e af' animal. and plant orga~la.sms indi.ca~tie the. me~tY~ods ~.n .the ddin~ -to arid. l~,f ting ~ax~winism ~ta clang a line necessary 'ta ma1? A ~ . ' r, er lane, ~ichux~-nisi science is revea~.~ a qua7.itat~-vely~ new and h~.~h p n es in b.eredity~ a.s equipp~.ng the waxkers ing the cause f'ar the cha ~ ~~. , thods for improving and creating new, hig y in stack~raisin~ with me ~'v breeds of agricuJ.tura1. aimals. producl~:>,. e [ picture on page 8 oftext s Kazakh whitehead pictures on page 9 of text Lebedin cow [ Second column, 'tOp l Second coiumn, center Sychebull C ~ ~~~~~ ~~~~~ ~ E~~ ~~~ '~ ~,~,' ~ ~, ~~ ~~~~' ~ ~~ ~. ~~ ~ Declassified in Part - anitized o F ak z~~w ~f't4f~ .e I,f~I ';. ~!i, . i. i r1, ~G, ~,I';, ~~ ~hu,1a~~~n vsa ~,. ~ and ?~he record shearing .for ~;h~s breed is a l~a,~., 22.3 kjlograms. P1t~ sheep, ~n~ ~.ch are l+sn cla.s~a.x~~;uz.sh~d by :LarGe , f -h?~ are well adapted to prolvnged winter sub- s1~~eai~.n~s and live ~?~ea.~. ~ ? to conditions of ?Lhe harsh Siberian climate. ~a.s ccnce under il,eni breed of Sa])sk fine-j'leece sheep has been A new, exce bred by the sca.en?E,a.~ and experts in s?t;ocl~~z~aising at the Hose ~ ~~? ~s ar `arm lrnena. S. ., ~ ~~ os Gov Oblast, The avera~;e shcari.n~~ of 1~~. T~uden~~y, h fine-fleece sheep o:C the e new br'er'd arnountec1. in 19L6 to .9 kilograms : . and in J.9~0 to ?.l. ~ .a ~, 'ska and also the Stevropal ~ breeds of The ,~ sheep, whose breeding ,:n~; was ~ completed in recent years, are a highly. praduc of sheep. Ram No ~.ll of S'~avl~apol t breed productive breed of wool a live weight of 12f kilogr~~rns and gives a shearing of finewfieece w kilo grans per year. This is a world records amoun~~~.nf~ ~,0 2,.3 g the develapmenL of new breeds of sheep an the basis of has a ~mitbec~,.regions with harsh or specific l~i.chur:a.n~.slsc.~ ~.encc l~a~~ pcx ~ with fine or seini-fine fleece could not be c()nda.t~.onay where sheep ,hccp w' ~. sin~f regi0z~s. In southeast ~~aral~.stan such bred, to become sl~~;ep r~~,,' ~. b breed, which is -~xce:l.len~ly adapted ., breeds - are the I~ar~,ld~ :Ln.newf.'~.cecp ~ b to the steppe and sere.s1, ., -ePpc ? ,, pasture ' lands of this region, and in the mauntail~ regions such breeds are kraakh arlthrnmerLno. The deve r of new breeds of farm anin~.ie, to increase development n Part - Sanitized Corv Arroved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 roductivit^ 01' bi; horn c ttie, shop and swte poii t to the in tho p ~ 1 i1i'ties o our Fathor1 ~nc1 , toclc~raising. In the ~,nc~xl~at;ll~:lo pose. , decrEo ley the Party anal the CTQVC~nl11on't on the Three ;& r Plan Cor the devc1?pmc~n .~t off stock?bre din ; in i9L 9~i9 ii soviet scientistS and workers ti rra,cu .tux^o are presented. th responsible taks. in Ea These tasks have this objective: using all, the means o;' modern zQOM flee based on the achicavements off' )'ichurini$t bioio y, teolanioa:L ~u'ie to produce an abundance of products of stockMrai$in in our country. rf'he wide ua G. 1i.Cburini$t rr~ethodin practioc will allow us to of ~ succeSSfui.yti,i~,f' the plan qualitative transformation and irnprove~ merit of productive stock-raiSin(, to attain new suoce3~3o5 and achieve ments in this work. Declassified in Part -Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035 1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 STAT 'old Tip HISTORY OF CHINESE NiEDIOTNE prof a sor D. M. Ros siysa-?` Honoredactentiet The great Chane e people have enriched world cuituxe with s many impoxtant d:f.seoveries arid remar1Cab1~ acaia.eveman'~s in the fields of literature, art, and science Great importance can be attached to the works of Chinese sca.ent].~'is in the sphere of medicine, which had its inception N in ? China several thousand years before Christ and is one of the oldest medical sciences in the world. The discovery of blood . w ganism circu~.a't and it of the constant relationship between the human' or- ganism env h~; use of narcotics during surgicenvironment, t operations, the introduction into medical practice of the prin- ciples of preventive treatment, origination of many methods of ~. medical treatment,, discovery of many valuable pharrnacolog:ical and therapeutic ?nals , and a series of other ach~,etherapeutic rned.~oa. of Chinese medicine represent not only a vast historical interest, medicine repr but also v ies of importance to contemporary science. vital discover the beginning 7 of Chinese medicine is lost in the immemo- rial times of antiquity. A Chinese herbal ttShen_nUflbet5a0', dating from the tt' eth century BC, contained detailed des- ? criptions of many wan medicinal plants. `l'he most ancient Chinese boob, in which the medical knowledge of the Chinese people was is ttNeydzin" (Book on internal Things), collected and systemized, Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 written between the eighth and seventh centuries, BC; it has served as a handbook for many generations of Chinese physicians. The ancient Chinese medicine reckoned about 500 different human diseases. They were subdivided into infections of the large and small organs, into catarrhal, feverish, cutaneous, and ocular and into infections of the oral cavity, teeth, neck, diseases, bones, and others. Chinese physicians correctly believed that it was easier to prevent an illness than to treat it, and that it was also eases ic r to preserve the health than to restore it when it was dis- turbed. In treating a patient, the principal attention was con- the causes of the illness. Chinese medicine had centrated -upon d the greatest importance to prophylactic methods always attache Chinese doctors, long before Europeans, had dis- of treatmenL4 covered and put into practice the method of preventive treat- merit of smallpox by means of prophylactic inoculation. The doctors of Ancient China considered as an outstanding method for diagnosis the examination of the patient, his auscul- tation, goestionin, and examination of his pulse and urine, to the modifications of which they attached gread diagnostic impor- Lance. Owing to their superficial knowledge of human anatomy, the doctors seldom used the surgical methods of treatment. This poor know/edge of anatomy was due to the religious prohibition .... against performance of autopsies, n the ancient Chinese book "Neydzin" we find hygienic Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 advice, some anatomical and phyaio1ogioa1 -fformation, desoxip'' t,tons of 3 sinptoms of diseases and methods treatment, we find there ala descriptions of mae ages, of acupunctUra (needle pric1 ' es n and mox (cauterization) , therapeutic methods that were very much used in China for treatment of various diseases The ancient doctrine of acupuncture is based upon the. of Chinese physiciansthat each internal human organ has theory two corresponding passeges symmetrically arranged and shaped in the form of tubes Blood and pneuma flow through these tubes) and f%heir passage are 'located the so~called "vital points .t' By inserting needles into these "vital points," the Chinese physi'- 'ans tried to influence the course of disease of the affected ca~ a organs , giving the disease the availability of an out- let. Chinese medicine reckons more than 3a "pointst' of appli- cation for needles, and these "points 't are sometimes loomed ra- ther far from the affected organ. According to Chinese physi- cians' observations, the curative effect produced by introducing the needles depends upon the duration and the depth of the prick. Needles for acupuncture are made from gold,. silver, or steel. There are usually about 40 types of such needles in a set; their sizes vary from l to 2 centimeters. In some "vital points" the A7 ~. J needles are inserted perpendicularly to the muscles (for example, the calf of the leg, the shoulder, etc); in other locations, where the muscles are smaller (hands, forearms), shorter needles are used and are inserted parallel to the muscles. Chinese litera- ture describes many cases of successful use of needle insertion Declassified n Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 during vaxiaus disessea, sspecia11y diseases of funetio1ai chaxac~ obtained by this method of txeatmeflt hex. The therapeutic effect is explained by th? action of those needles upon the nervous eys in inf1uenco. on all pracvsses of the tam, which has an outstand '- ~' body's activity. The txeatmen't by ma n$ of 1tmox" (cauterization) of "vital used in Chinese medical practice. This paa.nts'I is also very much method of treatment can be considered as a particular method of and as an application of biogen stimulators, which protein therapy are developed in the tissues after cauterization, and which stimu" sate the physiological and regenerative activity of the organism. . As an external treatment, Chinese medicine has used massage since most remote t Massage is administered either manually ~.me,r ~. or w:>.. t .h the a~ apparatus. The rmanual method consists aid of special of rubbing, kneading, and slapping with the hands, palms, or r, and even of pinching. The massage instruments consist of flsta hammers of various sizes, with which the therapist small wooden the muscles of the affected parts of the body. For the trikes s massage of chest, backs and limbs a kind of spade-shaped appara- tus -'- usually made of gueiacum or logwoad ...., is used. The skin of the body vigorauslY with the wider end of the spade ..... IS . rubbed which has been soaked in a mixture of water, oil, and salt. This the skin becomes completely red Abdominal is continued until massage is performed by means of a device composed of two rolls rotating an one axis. In order to obtain elasticity of the hands, Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 srootb stone balls or small rolls are used. Chinese medical science has always paid special attant,Lon use off' medicinal plants Chinese physicians averred that to the tt'thexe was no plant that could not be employed as a medicinal sub stance." They al;ao proved that differ&it parte of the same plant buds leaves, bloom, >rlnd roots - possc:se different medicinal properties, and that for medical purposes they must be gathered in specific seasons of the year. Numerous Chinese herbals and pharmacopeias that were com piled long ago contain detailed descriptions of medicinal plants. As earl as the year. 2037 BC, a special herbal, apparently the oldest one in the world, was compiled in China; it contained apw roximately 100 descriptions of plants posses dng medicinal pro- p erti.es. The great majority of almost two thousand medicinal re- p medies mentioned in 'tBen-tsaoWgan-tnu" -- a 52 volume Chinese phar macopeia of the sixteenth century - belong to the vegetable world. The following medicinal plants are used in Chinese medi- cal practicet aloe, aconite, belladonna, hawthorn, valerian, pomegranatet camphor, Indian hemp, lemon, poppy, almond, myrrh, nutmera juniper, mint, fern, pepper, wormwood, rhubarb, camomile, ~, fennel, garlic, saffron and many others. Drugs prepared from gin- send; and Chinese lemon tree were widely used, Ginseng ("man roott') has been known in China as a medi- cinal remedy for approximately three thousand years. Chinese medical science calls ginseng "man root" and 'tworldts miracle" be- Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Gurusa old Youh again and restores debilitated men 'it . makes ~lae ~ to good haa ot of ginseng i$ c~spsc~,aa,~,~; ~va~.L~ed, Tet$ The xo n.A carried out' by Soviet sci,enti,sts proved of ginseng preparatio their in vanes in a ser1e?3 of diseases, i~nc~.udM dispu~a~le a.'ec~,i ing diabetes, ,~Ser~-~sao?~anwmu" C~aineso In the i'amaus pharmacopeia the in the first category of drugs which are roaom- ~,emon ~trsE; is pus a. min:i.stered for restoring energy in cases of over- mended to be ad fatigue, for reguatin respiration, for improving spirits and ~. ~ Chinese ca1?t it "oo~way-tai" whicxi means sexual functions, The "fruit tae," Immediately -after taking one "fruit t , with five testae." ImmediatelY after taking one dose of th s dr harmacoPeia, " a man' S vitality` in- creases." In accordance with the task assigned by the Biological De- partment of the USSR Academy of Science, the Special AU-Union ~' Committee for Vegetable Resources has conducted numerous experi- mental and clinical teats of the Chinese lemon-tree preparations and stated that this drug increased intellectual and physical ef- improved the keenness of visian. The cansiderably a. ficiency an ~ Chinese an is a valuable stimulant in the lemon trek; preparat?~. case of long absence of rest and sleep. We have also carried out various tests of a series of other medicinal plants used in Chinese medical practice. Among others, we tested the preparations of hawthorn, which are now uccessfu 'ntered in the cases of heart disease, prepara- s~.ly adm~.~.s Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 t:L?n~ of magnolia that produce a c1eariy pronou apd tharapeuti.c ease as well as other remedies ff?ct iii cas of hypQrtani dis, ees c from medicinal plants. prepared al therapy a1$O uees preparations from Chinese pharmaceutic tissues and organs of animals. Yaun not yet ossi,fi.ed, horns of . Siberian spec been used, by tlla ChinaSe pc~oplp ;since ki.ed deer have long ago. Actually the Itpantocrine" prepared from these. hart. . known as an excellent remedial tonic. shorns a.s very well medicinal remedies of mineral origin, preparations Among from gold, silver, copper, mercury, arsenic, sulfur, and lime in China sialce very remote times. have been utilized . In the first half of the medieval period, Chinese medi- the influence of various religious and mys- cal science was under tical doctrines and therefore experienced a period of stagnation and decline. Only.. in the second half of the Middle Ages did it gradually liberate itelf from religious and mystical ideas and s begin its s progressive development. At the beginning of the 19th century, Chinese medicine was put on a scientific basis and began . to develop more rapidly. But only after the victory of the Great after the formation in 1949 of the Chinese People's Revolution, and People's Republic, has the course of medical science attained the highest level of its levelopment. In that same year. the Ministry of Public established in Chinas The Chief Anti-Epi- demic Administration, I~ealth was with branches in evez'y region of the coun- try, was organ the People's Republic; the State Sanitary organized in Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1 Administration way created, and sanitary epidemiological and new bacteriological institutions, hospitals,, and po1ye1iniea were opened. Widespread work has developed iii the field of communal hygi`%e In 1950, for the first time .n the history of China, the law establishing compulsory, free antismailpOX-vaocinati.on waa enacted. This year, an alas-Chinese Conference debated the prob lems of organization of prophylactic and,anti.~epidemic measures. Concerning this Conference, Mr. Li.-De-C1ian, the Minister of Pubs- lie Health of the Chinese People's Republic, gave a report on the re~aults of the anti-epidemic work accomplished in 1950 and on the tasks anticipated for the future? The Communist Party, the Government of the Chinese People's Republic, the local authorities, and the trade unions are exerting their utmost in the administration and development of the public health program. Medical science is successfully progressing in the country, and the research work in the area of prophylaxis and treatment of diseases is developing rapidly. END Declassified in Part - Sanitized Copy Approved for Release 2012/05/08 : CIA-RDP82-00039R000200100035-1