ACHIEVEMENTS IN MAGNETOBIOLOGY

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CIA-RDP88B01125R000300120010-0
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5
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December 22, 2016
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May 10, 2012
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10
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REPORT
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STAT Declassified in Part - Sanitized Copy Approved for Release 2012/05/10: CIA-RDP88BO1125R000300120010-0 PUBLICATIONS ACHIEVEMENTS IN'MAGNET0BI0LOGY Moscow REARTSIYA BIOLOGICHESKIKH SISTEM NA MAGNITNYYE POLYA (Responses of Biological Systems to Magnetic Fields) in Russian 19.78-,signed to press 24 Feb 78 pp 3-5 and table of contents [Introductory article by Yu. A. Kholodov, Institute of Higher Nervous Activ- ity and Neurophysiology, USSR Academy of Sciences, Moscow: "Achievements in Nagnetobiology", and table of contents from the above collection, Nauka, 2250 copies] [Text] Only six years have elapsed since the publication of the first col- lection of articles on magnetobiology [1] by the Scientific Council on the Complex Problem "Cybernetics" of the USSR Academy of Sciences, but there appeared many publications on this problem during this time (particularly in the USSR). All-Union Symposiums on Individual Problems of.Magnetobiology were held in Moscow (1971, 1972, 1974), Baku (1972), Belgorod (1973), Frunze (1974), Leningrad (1975), Kaliningrad (1975), and Yalta (1975) [1-4, 7, 8, 13, 15]. Monographs were published [5,6,14,16-18] and survey articles were written [9,10]. Dozens of dissertations on individual problems of the bio- logical effects of magnetic -fields '(MF) were defended, which indicates the de- velopment of this branch of biophysics in our country. At present, there exist not less than 2000 published sources on the biologi- cal effects of NF. Magnetobiology is discussed in textbooks [12,20] and in encyclopedias [11, 19]. Practically no one doubts the biological effect of MF, but the question of how this effect is realized has not yet been answered satisfactorily. There- fore, the mechanism of the MF effect on biological systems received primary emphasis, in the articles of this collection. In essence, each author gives some attention to this basic problem of magnetobiology, but articles treat- ing exclusively this problem are included in the first section of this col- lection. The authors of the articles in this section are of physicochemical specialization. Each of them stresses the aspect which is the most important in his opinion in the many-sided process of the interaction of MF with bio- logical objects, maps out various approaches to the solution of this impor- tant problem, and lays the foundation of a general theory of primary mechan- isms (it is clear that there are more than one) of the biological effects of rF . Declassified in Part - Sanitized Copy Approved for Release 2012/05/10: CIA-RDP88BO1125R000300120010-0 Declassified in Part - Sanitized Copy Approved for Release 2012/05/10: CIA-RDP88BO1125R000300120010-0 The second partbf the collection is written by physicians and biologists who focused their attention on the properties of biosystems (whether it is a mitochondrion or a? population of organisms). Here, an NF often plays the.role of a convenient instrument for studying a biosystem, although the ecological role of this physical factor is already reflected in some works. It is regrettable that the effects of weakened magnetic fields (FLT) on biological objects have not been sufficiently studied, and the role of biomagnetic fields in the functioning of biological systems and in magneto- biological responses is still not clearly understood. It is shown that organisms react to MF both through reflexes, just as to other stimulants; and directly, since MF have a penetrating effect and can act directly on the central nervous system. The second route of influence was demonstrated in experiments with isolated preparations.of the central ner- vous systems of mammals and with surviving nervous systems of invertebrates. It is interesting that the isolated central nervous system responded to MF better than the intact system [18]. We should also mention the third route of MF effects on the organism which is indirect in nature. The point is that aqueous solutions of many sub- stances, including drinking water and solutions of pharmacological prepara- tions, change their biological properties after treatment in MF [6]. Thus, by redirecting the effects, the researcher can vary the degree. of the influence of the same HF on a biological object for the purpose of control. The length of exposure also contributes to the nature of the response to an HF which is characterized by a long latent period and considerable after- effects. In the case e intermittent exposure, the summation of the effects is observed, which is used in physiotherapy [12], and when the exposure time is increased, adaptation is observed. However, the ultimate biological ef- fect is determined not only by localization and length of exposure, but al- so by the characteristics of the biological object itself. At the organism level, the response to the HF is determined by the specific and genetic characteristics, age (young organisms, particularly embryos, are sensitive to HF), sex (males are more sensitive than females), individual characteristics, and the functional state. The above information shows which elements of the biological system are most vulnerable to the magnetic effect,. but do not determine the degree of the biotrop?ism of individual parameters of this effect, The characteristics of the biological effectiveness of some MF parameters are treated in the third section of the collection. It was written by authors with engineering specialization. It is hoped that the information given in this section will help in raising the methodological level of magnetobiolo- gical experiments in which only the magnetic field intensity was mentioned most frequently. Declassified in Part - Sanitized Copy Approved for Release 2012/05/10: CIA-RDP88BO1125R000300120010-0 Declassified in Part - Sanitized Copy Approved for Release 2012/05/10: CIA-RDP88BOl 125R000300120010-0 It is also necessary to indicate the ME gradient and vector, and for variable MF, the frequency and the.pulse shape should be given. The length of exposure to the MF and its localization also determine the. value of the biological effect. The above discussions dealt with biological effects at fixed MF parameters. It was shown that the effectiveness of exposure increases if one or several parameters of the effect are varied during the exposure [19]. For example, an intermitteit effect is stronger than a continuous effect, and the effect' of changing frequency is stronger than the effect of fixed frequency, etc. It should be concluded that, by artificially changing the MF parameters, one can, to a certain degree, control the behavior of the organism, influencing in a contactless way its regulation systems.. - The ultimate goal of magnetobiological studies -- the possibility of control- ling the activities of biosystems -- can be accomplished by including feed- back in the circuit of the automated controlled experiment. The materials of this collection have outlined the ways of achieving this goal. It is hoped-that the complex theoretical and practical problems of magnetobiology will be solved through joint efforts of various specialists. Bibliography 1. "Effects of Artificial Magnetic Fields on Living Organisms." 1972. Materials of All-Union Symposium, Baku. 2. "Effects of Natural and.Weak Artificial Magnetic Fields on Biological Objects." 1973. Materials of All-Union Symposium, Belgorod. 3. "Effects of Magnetic Fields on Biological Objects." 1975. Materials of the III All-Union Symposium, Kaliningrad. 4. "Hygienic Evaluation of Magnetic Fields. 1972." Materials of the Sym- posium, Moscow. V 5. Dubrov, A. P. 1974. "Geomagnitnoye pole i zhizn "' [Geomagnetic Field and Life], Leningrad, Gidrometeoizdat. 6. Klassen, V. I. 1973, "Voda i magnit" [Water and Magnet], Moscow, Nauka. 7. "Space and Evolution of Organisms." 1974. Conference Materials, Moscow. 8."M4agnitnoye pole v meditsine" [The Magnetic Field in Medicine]. 1974. TRUDY KIRG MED IN-TA [Proceedings of the Kirghiz Medical Institute], Frunze, 100. 9. Maykelson, S. M. 1975. "Radio-Frequency Radiation. Magnetic and Elec- tric Fields," in the collection: "Oznovy kosmicheskoy biologii i meditsi-n [Fundamentals of Space Biology and Medicine], Vol 2, Book 2, Moscow, Nauka, p 9. FOR OFFICIAL USE ONLY Declassified in Part - Sanitized Copy Approved for Release 2012/05/10: CIA-RDP88BOl 125R000300120010-0 Declassified in Part - Sanitized Copy Approved for Release 2012/05/10: CIA-RDP88BO1125R000300120010-0 FOR. OFFICIAL USE ONLY 10. Nakhil'nits"kaya, Z. N. 1974. "Biological Effects of Magnetic Fields," KOSMICI1ESKAYA BIOLOGIYA I AVIAKOSMICHESKAYA MEDITSINA [Space Biology and Aerospace Medicine], No 6, p 3. 11. Novitskiy, Yu. I. 1973. "Magnetobiology," "Detskaya entsiklopediya" [Children's Encyclopedia], Moscow, Pedagogika, p 62. 12. Pasynkov, Ye. I. 1975.. "Fizioterapiya" [Physiotherapy], Moscow, Medi- tsina. 13. "Responses of Biological Systems to Weak Magnetic Fields." 1971. Sym- posium Materials, Moscow. 14. Travkin, M. P. 1971. "Zhizn' i magnitnoye pole" [Life and the Magnetic Field], Belgorod. 15. "Physicomathematical and Biological Problems of the Effects of Electro- magnetic Fields and Air Ionization." 1975. Materials of the All-Union Scientific and Technical Symposium, Moscow, Nauka. 16. Kholodov, Yu. A.. 1970. "Magnetizm v biologii" [Magnetism in Biology], Moscow, Nauka. 17. Kholodov, Yu. A. "Chelovek v magnitnoy pautine" [Man in a Magnetic Cobweb], Moscow, Znaniye. 18. Kholodov, Yu. A. "Reaktsii nervnoy sistemy na elektromagnitnyye polya" [Responses of the Nervous System to Electromagnetic Fields], Moscow, Nauka. 19. Kholodov, Yu. A. 1974. "Magnetobiology" BSE [Great Soviet Encyclopedia], Vol 15, p 167. 20. Beier, W. 1975. Biophysik, VEB Gorg Thieme. Leipzig. Achievements in Magnetobiology. Yu. A. Kholodov Physicoochemical Principles of Primary Mechamisms of the Biological Effects of the Magnetic Field. V.1%1. Aristarkhov, L. A. Piruzyan, V. P. Tsybyshev Magnetohydrodynamic and Electr.ohydrodynamic Effects in the Mechamisms of Magnetic Fields Acting Upon Biological Objects. Ye. Z. Gak, G. P. Komarov, M. Z. Oak Some Special Characteristics of the Effects of Pulsed Magnetic Fields on Conductive Liquids and Biological Systems. Yu. V. Berlin, G. M. Buvin, V. I. Bel'kevich, Ye. Z. Gak FOR OFFICIAL USE ONLY Declassified in Part - Sanitized Copy Approved for Release 2012/05/10: CIA-RDP88BO1125R000300120010-0 Declassified in Part - Sanitized Copy Approved for Release 2012/05/10: CIA-RDP88BO1125R000300120010-0 Some Biochemical Aspects of the Effects of Weak Low-Frequency Magnetic Fields. R. N. Pavlova, N. I. Muzalevskaya, V. V. Sokolovskiy Destabilization of Nonequilibrium Processes as the Basis of the Overall Mechamism of the Biological.Effects of Magnetic Fields. G. F. Plekhanov Bioenergetics and the Regulating Systems of the Organism Under the Effect of Magnetic Fields, M.A. Shishlo, S. Kh. Kubli, V. P. Nuzhnyy Magnetosensitivity of Microorganisms. S. A. Pavlovich Responses of Plants to Magnetic Fields. Yu. I. Novitskiy Magnetic Fields, Adaptation Responses, and Resistance of the Organism. L. Kh. Garkavi, Ye. B. Kvakina,M. A. Ukolova Effects of Magnetic Fields on the Blood System and Blood Circulation. R. P. Kikut Psychophysiological Analysis of the Responses of the Nervous System to Magnetic Fields. Yu. A. Kholodov Effects of Magnetic Fields on Natural Populations. M. P. Travkin Studies on the Biotropism of the Parameters of a Weak Magnetic Field of the Ultralow Frequency Range. N. I. Muzalevskaya, G. D. Shushkov Magnetophori and Magnetophorus Devices. A. S. Fefer COPYRIGHT: Izdatel'stvo "Nauka", 1978 10, 233 0 CSO: 8144 FOR OFFICIAL USE ONLY 178 209 Declassified in Part - Sanitized Copy Approved for Release 2012/05/10: CIA-RDP88BO1125R000300120010-0