SCIENTIFIC ABSTRACT SISAKYAN, N.M. - SISAKYAN, N.M.

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SCIENTIFIC ABSTRACT
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~;Ov/ - 59 -1 -4,1134 A~UTHOR: Sisak-"'q- N-M., Corref,-~ondiag Member 41S USSR; --DUPfft`y-=.e`f_B`cTentific Secretary of -,-.he 1-Fresidium, AS USSR TITLE: The Principal Trends of Science in the -even-Year Plan (usnovnyye napravleniya nauki v semiletnem plane) PERIODICAL: Priroda, 1959, Nr 1, PP 11-14 (USSR) ABSTRACT: The author reviews the present state of Soviet science with respect to the forthcoming requirements of the new 7-Year Plan. Soviet science envisages two principal tasks: a comparison of its present level and achievements with those of science abroad, and the concentration upon re- search fields that have maximum bearing on the fulfilment of the Plan. In the realm of physics, stress is to be placed or. controlled thermonuclear reactions, semicon- ductor technology, computer and programming technique, and problems of cosmic rays and phenomena in interplanetary space. Investigations in the field o *f chemistry should emphasize the development of artificial and synthetic materials, heat-and wear-resistant polymers, the Card 112 structure and mechanism of formation of biologically ~il,ijilrbdl, U.M.; I.M. Ifisiabrano c-? cliiloropjast. TiSitologila I no.4:366-368 Ji-Ag '59. (MVA 12: 10) 1. Laborat,-,-I,,-v~ enzimologii Inatitutu blokhimil k1l SSSR, Moskva. (CHPA)PATOPHORSIS ) SOV/30-59-4-7/51 The UNESCO and International Cooperation in the Years 1959-ig6o 1. P. Tsameryan and S. L. Ronin, staff wnbez!x of the Academy of Sciences of the USSR, prepared the following pamphlets to be published-by the UNESCO: "Education in Social Sciences in the USSR111 "Equality'of Rights of Races &4'*ations in the USSR". The Soviet scientists L. A. Zenkevich,: G_,1.'T..P?gomolov, Ye. M. Zhukov and V. A. Kovda work in various instituti6fis of the UNESCO. According to the authors' opinion the p~~ogram of the UNESCO may, in spite ok'several shortcomings, serve as a basis of international coopera"tioix. They'iegard it as a great mistake that the People's Republic of China is not a member of the UNESCO. According to^a suggestion made by the USSR, an Inter- national 06nfe:bence on Semiconductors and the Establishment of a Convention for Scientific.;-technical Collaboration is to be convened in the years ig6i-1962. An International Congress for Oceanography is to be convened in New York in September 1959 and a Conference on the Equipment of an International Research Ship is to be held in 1960. The periodical "Kurtyer YuNESKO" published the article "Solar Energy. Hopes and Reality" by the Soviet scientist V. A. Baum. A Conference on the Use of Elec- Card 2/3 tronic Computers is to be convened in Paris in June 1959. At SISAKrAN, N.M.; KRASNOVSKrY, A.A.; MIKHATLOVA, Ye.S.; BRIN. G.P. Photoreactivation of cytochrome oxidase activity in plant tissues containing and lacking chlorophyll [with summary in Nnglish]. BIG- khimiia 24 n0-1:3-8 Ja-F '59- (KIRA 12:4) 1. Institute of Biochemistry. Academy of Sciences of the U.S.S.R., Moscow. (GYTOCHROME OXIDASS) (PlMTS, ZMCT OF LIGHT ON) (CHUMOPHYLL) BEZOMGER, E.N.; SISAKYAN, N.M.; SIMkKOVA, I.M. Nitrogenous components of lipoids in plastid lipoproteins. Blokbimiia 24 no-5;876-884 S-0 159. (KIPA 13:2) 1. Inotitut biokhimii imeni A.N. Bakha Akademii tauk SSSR, Kooky&, (LIPIDS) (PLANTS--)WABOLISM) SISAKTAN. N.M.; FILIPPOVICH, I.I. Protein synthesis and cellular structures. Izv. AN SSSR. Ser.blol. 24 no.6:839-854 11-D '59. (KIBA 13:4) 1. Institute of Biochemistry, Academy of Sciences of the U.S.S.R., MOSCOW. (PROTEIN MXWOLISK) (FUR CELLS AND TISSURS) SISAKTAN, N.M.; KiMOSTAN, L.S. Amino acid composition of proteins In vheat grain. BiokhImII& 24 no.6.-1094-1103 K-D 059. (MIRA 13t5) 1. Institute of Biochemistry, Acadeaq of Sciences of the U*S.S.Res Moscow. (WHW Chem.) (ARM ACIDS chow.) KONSTANTINOV, B.P.; DEBORIN, A.M., akademik; FEYVE, Ya.V.; IOM. A.F., akademik; MIKHAYLOV, A.I., prof~-; SATFAYEV, K.I., akademik; ZHUKOV. Ye.H., akademik; LAVRENTIM, M.A., akademik; SIMINOV, N.N., akademik; PAVWVSKIY. Ye.N., akademik; MINTS, I.I., akademik; SISAKYAN, N.M.; ROMASHKIN, P.S.; FEWROV, Ye.K.; STICHKIN. B.S., akademik; MAYSKIY, I.M., akademik; PAVIOV, Todor. akademik; ARBWOV, A.Ye., akademik; VASILIYXV, N.V., doktor ekon.nauk; SWUSOV, V.V.; MITIN, K.B., akademik; BMGONRAVOV, A.A., akademik; KANTOROVICH. L.V.; RYBAKOV, B.A., akademik; I&MCHINOV, V.S., akademik Discussion of the addresa. Vest. AN SSSR 29 no.4:34-63 Ap 159 (MIRA 12:5) 1,Chlen-korrespondent AN SSSR (for KonstaXitinov, Pe7ve, Sisakyan, Romashkin, Fedorov, Belousov. Kantorovich). (science) 17(3) AUTHORS. Sisakyan. IV M- , Correspr;nding Yember, SOV/20-124-5-55/62 TITLE~ Or the 11ticleotirle- Cc,:nposition of the Nui-,Ieic Acids in the Silklyorm(Bombyx. Mori L.)(O nukleotidnom soutavi nukleinovykh ki,slot tutovogo sholk,.-pryada (Bomb- mori L")) YX PERIODICAL: Doklady Akademii raok SSSR, ~9179~ 1.1o). 124, Nr :5,. P;~ 1154-11506 (USSR) ABSTRACT: The nucleic acid oontent in Sombyx mori L~ is considerably .c,hang,~d in the Gou-7-ae of metamorphosis (Ref 1),. HIstolysis and +ic--ue differentiation are accompanied by its increased The amical. 7~ aofda is expressed among other thinga by %he nature of -Hle ratio between the purine and th" pyzimidInE., 'haaes lr- th,:. ribonueleic (RNA) and the desoxyribonv-,clolo a-1--id (DIIA). The theorem on the specifity of DNA was formulated,; Since no considerable differences were observed in she nur~!eotide somposition of the RNA (in toto) of m---~~r~Dorganiams, the problem of their, ..' -' F, sti.111 ur-sollved, The authors in-7estigated the ccmposition of the RNA in Bombyx morit -W,- in t,,-,o 'by quantitaf:ive paper Card 1/3 chromatography and spe-trophotometry (a--~Cording so Ref 10 C On the Nucleotide Composition oi the Nucleic Acids SOV/20 - ~ 724-5- 551/62 in the Silkworm(Borribyx Mori L,I with some modifications), During rietamorphosis the following 4 nucleotides could be identified and determined in molar per centsl Guanylic, adenyliz, uridylic, and cytidylic acid (Table 1). The TUTA investigated shows the general regularities which are oharac~teristic of the native comDosition of PITA (Ref 7'j. The number of the 6-keto groups is equal to the number of the 6-amino groups, i.e. the molar content of guanylic, + uridylic acid is equal to the content of adenylic -~- cYtidylic, w~id, On the basis of this general regularity ail RI-47 a~:;ids may belong only to three types-. a) with a p~fQdomlnant content of biianylic and cytidylic acid as compared with the adeny`a.,~ and urldylic acid (GC type); b) tetranucleoti~-e iypej c) with predominant content of adenylic and uridylic az~id over that of guanylic and cytidylic acid (AU type), The RIFA of Bombyx mori L. belongs to the AU type in contrast to thin RNA of microorganisms (GC type, Ref 5) and remains the same during metam6rphosis. The ra-cio bezveen parines and pyzimidines is not so high as in the RNA cf mcrcorganis!.,is. The DNA content is, on the Card 2/3 whole., 5-ow -*;_n Bombyx mori L, At present, only eggs taken from On the Nucleotide Com-oosi.rior, of the Mucleic; Acids SOV/20-1124-5-55/62 in the Silkworm (B6mbyx Yo-ri L-) ASSOCIATION- SUBMITTED. femal chzys&L--'ses were investLgated, and the rer cent sontent of purines and pyrimid-ines is 1E-~ermined- Also in this case grenera. rag-alariti-,~s in the mTposition of the native DITA WeTe observed (.Ref 3) , Pur-rher Invest.i.-ations are necessary in orA-er to find the la--k or preseric-e of eseent-i-al differences between the RITA of inse%~ts and --hat of other ani'mals which were found in the present paper There are I figure, 1 table, and '.2 referenvea. 3; ef whj~:;ft are Soviet Instilut blokhimi4- im, A. (Iristitilte of Bio~~hemistry of Sc'Len;-,e6 US'SR) N. Dakha Akade-aii nauk SSSR iruni Ar. TV Rakh of the Academy Desembei 22, -.35.6 Card 3/3 7(171) AUTHORS: S--'Bakyan N. M,, Corresponding SOV/20-124-6-44/55 Memr-er AS USSR.~ P~'nuaj Ye. A. TITLE, On Faetcrs Affe,:ting Glycolysis (.0 mit-~,khoadrl*a!~Yjykh fakt.,)rrikh, vIiyayushchikh na glikoliz) PERIODICAL, D;:.k--,ady Akademl-i nauk SSSR,, 1959,., Vol 124, Nr 6. PP 1342-1343 (USS'R'i i ABSTRACT;, The yr-1Lr.-,--ipa1 ox.--diz2ngr p-rooesses of the cell are consentrated Y.r 'he m-*t-,chond=-.a whe.Teas the glycolytic reactions are 'r es-i 24,n, the soluble cell fraction. Several aij.~h.:szr-, zrez- at--,.- tc st-i'mulate the glycolysis of the soluble ly the ar~tion of mitochond-ria (Refs 2, 3), whereas ~)tbers fRefs 4, 4, , .5) obaerved, on the contrary, an inhibition of 1h; aer-,At:I7 g-y,:o-ys4-s; this enabled them to put the mechanism ,:f a`-or of 'k.-he mitorhondria in relation to the Pasteur effect. Ccmpj---~x are exist-ing between the glycolytic pr-~~esses if the soluble fta--~tion and the mitochondria added. Th,~: nator-r- *f the m--.Tonh-~ndria effent (inhibitory or dep;zkds on +he c~,nz~entration of the added Card 1--c--hond-n;i and )- the sucstrate applied, The inhibitory On 1A.'tochardr-'a' ~rfenf-"-.ie G'1y,7--,1ys4_S SOV/20-124-6-44/55 ef f e,: 'ak=-s pia,~e in the stage be-tween the glucose-6-phcsphate SnA d'ph:~spb3te,.~ whereas -,he stimulating effect be!,omes msn-.1is- after -,-he f3rmation of the latter substance. Both 1-berm-.1a"Dile, The authors tried to separate the fa:~-j'.(,, A,3 109y t-1 s-ze-c f-r,)m table 1, the glycolysis- I h r ;, - -?~ ~ -, i f jta .:,)n,,er-trated mainly in the light The a,.ith:,~rs con,~'ilade Therefrom that the inhibitory ;f f1h.? mi.-~-,;chondr_-'EL apparently is formed by the light f EL '-n- fra:,Vor, awox.Ts t:o about 25d;o of the fraction of The bas._-'~:, fract.'on of mitochondria exerted in -zr,~irimentq no ii*jbibitory effect at all or a less '-ban fh~- '.1ght fra,~tinn. The microsomg fraction effr-.1--t -~n gly,~ollysis, It may be taken for JP'+o-bo.Pdj-1.aL fa.:~t.-_~rs are thermolabile and th~- a ii-i of the mitochondrial structure. factcr --an be extracted from the mitochondria whi.-h had b,~-en dsstrcyed by freezing and thawing, whereas the ss-Aivity is mainly concentrated in the -dr'a f:ra,,.t-ion, -'here are 1 table and6 referencesq gh t h .- , L J. -_ f w hi i i s S -~ - -. -_ '-f ~` ~ SUBMITTED, D P-11 - 91;8 Card 2/2 SISAKYAN,--N.M.; MARKOSYAN, L.S. PAIrin qualities of flour from certain vheat varieties in Armenia. Bi"hia-zerna no-5:65-86 160. (KrRA 14:5) 1. Institut biok-hi-ii ineni A.N.Bakha AN SSSR. (P.--Onia-nmr) SISAKYAIT, N.M.; YF*OROV, I.A. Some problems in the chemistry and biochensitry of cognac production. Biokhim. vin. no.6:5-15 160. (MLRA 13 ', 10) 1. Institut biokhimii im. A.W. Bakha AN SSSR. I (Brandy) ,~SIS4TkNv N.M.I_PDINTSOVA, M.50 Nucleic acids in cellular structures of plants. T-zv.AN SSSR. Ser.biol. no.6.-817-850 N-D 160. (MIJU 13:11. ) 1. The A.N.Bach Institute of Biochemistry, Moscow. (NUCLEIC ACIDS) (PLANT CELLS AND TfSSUES) \ o SISAKfkN, N.M.; FILIPOVICI, I.I. Synthesis of proteins and cellular structures. Analele biol 14 no.2: 39-56 Ap-Je 6o. (EW 9:11) (PROTEINS).. (CELLS) - 4ISAKYAN, N.M.; ODINTSOVA, M.S.; CHIMSHINA, N.A. &Lcleotide composition of ribonucleic acids in cellular structures of plants. Biokhimiia 25 no.1:160-163 Ja-F 160. (KIRA 13:6) 1. Institut btokhtail Iment A.W. Bakha Akadsmii nank SSSR, Moskva. (RIBOMJCLEIG ACID cham. ) (JIUCLAOSIDIS AND JIUCLIPOTONS chem. ) A. 86227 2 1 Z, S/030/60/000/011/003/026 2DDO B021J/BO59 AUTHOR: Sisakyan. N. M., Academician TITLE: Problems of Biology and Space Flight PERIODICAL: Vestnik Akademii nauk SSSR, 196joso- 11, Pp. 15-24 TEXT: In the present paper the author elucidates some results of investi- gations and the biological viewpoints of future manned space flight. Ex- periments showed that the living conditions necessary for living beings can be given during 3 to 5 hours by means of hermetically sealed cabins with oxygen regeneration,. In the event of failure at an altitude of 78-85 km at 2000 km1h or at an altitude of 39-46 km at 4100 km/h, ejection by a cata- pult proved to be the safest method of leaving the rocket and, apparently, did not affect the physiological functions of test animals. If the space cabin is leaky, space suits with a helmet instead of an oxygen respirator proved to be effective for saving the life of the test animals. They warrant safe flight and return from an altitude of 76 - 85 km, with a total of 50-65 min spent in the upper strata of the atmosphere. Experiments showed that imponderability during 3-10 min does not cause any essential changes Card 1/3 86227 Problems of Biology and Space Flight S/030/60/000/011/003/026 B 0 2',/BO59 in the function of circulatory and respiratory systems of the test animals. In connection with manned space flight, new problems arise for science: Space flight conditions and the physical state of cosmic space must be in- vestigated; the effect of space flight upon the organism of man must be examined; operational reliability and particulars of all systems have to be studied in order to warrant safe flight into and return from space for man. Man has to be protected against the following dangers of space flight: too low pressure; shortage of molecular oxygen; influence of cosmic, ultra- violet, and corpuscular radiation; bad temperature conditions; meteors. Little is known so far about the effect of radiations upon the human organ- isms. All this shows that man cannot exist in cosmic SDace without protec- tion. Moreover, noise, vibration, acceleration, and imponderability during flight are pointed out. The influence of terrestrial gravitation on the circulatory system has still to be examined. Much stress is laid on will- and physical training of the future space men. Pressure in the space cabin may vary between 760 and 405 mm Hg. Carbon dioxide content in the cabin should not exceed 1%. During the active part of the flight, which was ac- companied by continuous accelerations and vibrations, the test animals had a raised pulse and respiratory activity. Examination of blood and urine of the animals after their return to the Earth showed no permanent disturb- ances of the metabolism of nucleic acids. Biological studies are being Card 2/3 "')/V Al /" - SISSAKIAS? N. Y'. (Ussa) "Biochemical Functim of Cell Structures." Report presented at the 5th International Biochemistry Congress, Moscow, 10-16 Aug 1961 D2HSKJKHADU, Konstantin Helitonovich; SILOAKTAXg 4" akademik. otv.red.; SWOVATOVA, I.B.. red. Izd--vi7._VOLKOVA. V.7., takhn.red. LTea cultivation and production in the Chinese People's Republic] Kuliture i proisvodetvo chaia v Kitalskol Narodnoi Respublike. Moskva, lad-vo Abmd.nauk SM. 1961. 159 P. OMU 14:3) Whina--Too) 5/026''6 1/0001/00 1/0 0 11,00 7 A166/A027 AUTHORg Sisakyan. N IM Academician TITLE~- Biology and Space Flight PERIODICALi Priroda, 1961, No. 1, PP. 7-16 TEXT- Soviet experiments with animal-bearing rockets show that at heights of 78-65 km and speeds of 2,000 km/hr or at 39-46 km and 4,100 km/ hr catapulting is the reliable emergency escape method and causes no great functional disturbances in the animal. Space helmets are the best precau- tion against sudden loss of cabin hermeticity and ensure a descent from 78- 85 km with 50-65 minutes in the upper layers of the atmosphere. It has also been found that 3-10 minutes of weightlessness cause no great func- tional lesions to the animalts cardiovascular or respiratory system. No changes, genetic or otherwise, have so far been noted in the bacteria and phages contained in the second Soviet space ship. The deoxyribonucleic acid, H~La cell culture and human and rabbit skin tissues showed little difference from the control specimens. Subsequent regrafting of skin strips contained in the ship proceeded bimilak to that of the control samples. Card 113 Biology and Space Flight S/026/61/000/001/001/007 A166/AO27 Experience has shown that certain measures will be needed for manned space flight, especially as regards lessening noise and vibration during the active phase of flight. Man can best withstand gravitational stresses when they are directed chest-back, back-chest, left-right or right-left. The worse effects are sustained from stresses applied longitudinally to the body, especially from feet to head. If the astronaut is in a semi-prone position he should be able to withstand great stresses over a considerable period of time. Experiments with the dog Laika showed that the respiratory and circulatory functions approached normal during weightlessness but took 3 times as long to reach normal as in the Laboratory tests, probably due to the effects of weightlessness. Prolonged weightlessness would seem to cause no great changes in the main physiological functions. Experiments with Belka and Strelka indicate that the body can more easily withstand the transition from acceleration to weightlessness than the reverse. After prolonged weightlessness human acceleration endurance is reduced by approx- imately 2 units. The USSR has been systematically experimenting with the recovery of nose cones, together with animals and all necessary apparatus, to a total weight of 1,700 kg. The problem of carsule recovery has now Card 2/3 Biology and Space Fli~aL SIO 2 6/6 1/000/00 1 /001/00 7 A166/AO27 been solved. During the active portion of the flight, accompanied by prolonged acceleration and great vibration) an animal's pulse and re3pir- ation rates rise sharply but fall upon transition to weightlessne8u, reaching almost normal after some 90 ininut4s. Studies of the biochemical effects of cosmic radiation during space flight are continueing. Apparent- ly no stable changes occur in the nucleic acid metabolism. In the case of Strelka and Belka an abnormally high quantity of alpha-globulin, serum mucoid and .-eneral protein was noted a few days after their return to earth. There are 8 photos. Card 3/3 2281151 5/030/61/000/004/004/015 27, 0000 0 1 B105/B2o6 AUTHOR: -Sisakyan, N. M., Academician-Secretary, Academician (see Aaaociati6n) - - TITLE: Department of Biological Sciences PERIODICAL: Vestnik Akademii nauk SSSR, no. 4, 1961, 40-45 TEXT: In his annual report, Academician N. M. Sisakyan, Academician- Secretary of the Otdeleniye biologicheskikh nauk (Department of Biological Sciences) pointed out a general rise in the level of scientific studies of the Department. Many laboratories and institutes of the Department partici- pated in the biological studies on space ships. Material on the effect of space flight on the functions of living organism is so voluminous that its evaluation will take some time. The following research results were obtain- ed during the last year: The initial links of individual processes of meta- bolism were reproduced on modeling systems of the type of coacervates; the synthesis of the group of amino acids by plants was studied in detail; the ferment of the alanine dehydrogenase was separated from yeast cells. Certain results were also achieved in the study of the ultrastructural Card 1/5 22849 Department of ... S/030/61/000/004/004/015 B105/B206 organization of viruses, bacteriophages, bacteria and the biochemical properties of the functional cell structures. The study of the energetic states of biopolymers was developed at the Institut radiatsionnoy i fiziko-khimicheskoy biologii (Institute of Radiation- and Physicochemical Biology). Theoretical and practical studies in the field of microbiology were also conducted. In 1960, studies concerning the bruding of rich- milking cows were developed at the experimental "Gorki Leninskiyell farm of the Institut genetiki (Tnstitute of Genetics). At the Institut vysshey nervnoy deyatellnosti i neyrofiziologii kinstitute of Higher Nervous Activity and Neurophysiology), the quantitative analysis of the data of electroencephaloscopy was realized by using electronic computers. At the Institut fiziologii im. I. P. Pavlova (Institute of Physiology imeni I~ P. Pavlov), methods of the information theory were utilized for studying the visual analyzer. Important studies in the field of plant physiology, soil- and forestry science, flora, and fauna of the country, parasitology and ichthyology were conducted. The main shortcomings in the scientific activity of the institutes of the Department are caused by the fact that in many fields of biology, research applying latest methods, such as physico- chemical ones, has not been developed sufficiently. Inadequacy of the Card 2/5 1 22 1'. 4 9 Department of S/030/61/000/004/004/015 Blor/B206 introduction of new methods in production, publication of monographs, manuals and reference books, as well as of the activity of the nauchnyye sovety po Problemam (Scientific Councils of Problems) are criticized. Measures were taken to strengthen the links with the Otdeleniye Khimicheskikh nauk Department of Chemical Sciences), Otdeleniye Fi.~iko-matematicheskikh nauk Department of Physical and Mathematical Sciences), VASKhNIL and Akademiya ~ meditsin3kikh nauk SSSR (Academy of Medical Sciences USSR), Lack of Control is described as one of the main shortcomings. ln adalilon, Academician V.. N. Sukachev gave a short survey on the scientific and scientific-adminis- trative activities of the members of the Department for the periods of the report. Academicians I. V. Tyurin, V. A. EngellgaTdt; I. S, Melekhov, Academician VASKhNIL and Ye. M. Kreps, Correspond-ing Member AS USSR) reported on the most important studies,tasks,and requirements of the institutes. A,~ademician A, I. Oparin reported on the necessity of developing evolution "':--Dchemistry, G. M. Frank, Corresponding Member AS USSR, on the application c' electron microscopy, Academic~ian I. S.. Beritashvili and E. A. Asratyan, Corresponding Member AS USSR, on the development of physiology. M. S. Gilyarov, Doctor of Biological Sciences and Ye. M. Lavrenko, Corresponding Memb4r AS USSR, dealt with various probleme and G. A, Deborin, Candidate of Card 3/5 22849 S/030/61/000/004/004/015 Department of B105/B2o6 Biological Sciences, reported on the preparation of the Congress on Bio- chemistry in Moscow in August 1961. S. Ye. Severin,Corresponding Member AS USSR, P. A. Baranov and B. Ye. Bykhovskiy reported on shortcomings of accounts, Academician Yu. A. Orlov on storage of collections. Acadef'uician A, L. Kursanov mentioned the necessity of strengthening links between Department and practice; I. G. Bazhenin, Doctor of Agricultural Sciences and V. 0. Mokhnach, Candidate of Chemical Sciences, reported on various shortcomings, L. M. Metlitskiy, Doctor of Agricultural Sciences, F. E. Reymers, Doctor of Biological Sciences and P. I. Lapin, Candidate of Biological Sciences, reported on the exchange of experiences. N. D. Iyerusalimskiy, Corresponding Member AS USSR, M. S. Mitskevich, Doctor of Biological Sciences and Academician V~ N. Chernipovskiy reported on the insufficient utilization of research results of their institutes in national economy. L. A. Tumerman, Professor, and G. K. Khrushchov, Corresponding Member AS USSR, dealt with the problem of caders. A, M.. Kuzin, Correspond- inG Member AS USSR, and G. K. Skryabin, Candidate of Biological Sciences, rerorted on international scientific links. I. I. Tumanov, Corresponding Member AS USSR, dealt with problems of housing and equipment. In tLe discus~jion of the report, the followina scienti-3ts participated as t-uests: Card 4/5 S/030/61/000/007/003/003 B105/b2M AUTHOR: Sisakyan, N. M., Academician, Academician-Secretary TITLE: Discussion of the report by M. V. Keldysh PERIODICAL: Akademiya nauk SSSR. Vestnik, no. 7, 1961, 65-66 TEXT: The author states that'biological sciences are becoming increasingly important within the system of natural sciences and a thorough study of the processes of vital activity is expected in the second half of this century. The main problem of modern natural sciences is the photosynthesis, and the culmination of biological sciences is the knowledge of the activity of the human brain. Radical changes of the technology of biological experiments led to important achievements, especially during the investigation of proteins and nucleinic acids. Biochemical research opened up great possibilities of using biologically active proteins, the ferments, in industry. In 1958, it was decided to establish some plants for the manufac- ture of purified ferment preparations, but the Moskovskiy gorodskoy sovnarkhoz (Moscow Municipal sovnarkhoz) and Kalininskiy sovnarkhoz (Kalinin sovriarkhoz), mentioned in this connection, have practically done Card 1/2 S/030/61/000/007/003/003 Discussion of the report by ... 3105/B206 nothing to realize this project. Although re5earzh by biologists showed the important part played by microelements in the life of plants and animals, nothing was done to produce these microelements. In conclusion, it is stated that a great number of shortcomings exist in coordination and the introduction of research results into production. The extent to which many scientific institutions of the country are consulted for the solution of important theoretical problems is insufficient. The scientific councils for these problems do not introduce new research methods sufficiently, and seldom hold discussions. Serious shortcomings also appear in the training of scientific caders, where more attention should be paid to mathematics, physics, and chemistry. N. M. Sisakyan finally mentions the resolutions by the TsK KPSS arid Sovet Ministrov SSSR (Council of Ministers USSR) in this field. ASSOCIkTION: Otdeleniye biologicheskikh nauk Akademii nauk SSSR (Depart- ment of Biological Sciences of the Academy of Sciences USSR) Card 2/2 S/029/61/000/009/004/006 D037/DI13 AUTHORi Sisakvan~ N.M., Academician, Secretary of the Department '_t-gae 'Association) TITLEa Physics and. o.hemistry a:re changing the face of biology PERIODICALi Tekhriika rnolodezhi, no. 9, 19612 15 TEXT: This article deals with the study of biological problems in the light of modern physi.~s and chemistry. The author reVieWB in particular: (1) the study of the stru--.ture of protein molecules; (2) photosynthesis; and (3) the study of n,::rebxal acti--,rity under unusual conditions. Due to modern technical means used in biological experiments, the structure of such important biologi,,,ally a-_-.tive proteins ai insulin2 hemoglobin, etc.. has been established. Tha problem of the enzymaiir. synthesis of nucleic acid has been sol7ed and bi-D-,hemiats are approa-,hing realization Of the artificial synt_r,~sis of molec-ules. The author stresses the in- creasing significaztc~e of photlsyTLrhesis in agriculture. The highest ef- Card 1/9 S'/0 29/61 /0001/tOc/0 04100' PhysiGs and :,,--emlS:~7 .... DO,z7/ D 1 ficienoy of phot--.5:/nI-,1~-SI6 ~~aa be with unicellular algae oultures (chlorella) wheze abo,:Lt- 25-% of the atsorbed light energy c---- 'to harnessed against 3 to 5% in tne fi-~Id. T~-e study of the structural and metabolic bases of excitat-lon ar,,,,' innit-J,.ion opens new possibilities of a directed regulation of the basi., Lerqo.~~- pro-,esses. With regard to spacp flightB, the author undeilines th-i of increasing the efficiency :,f the brain without harming tii4 -,rgar~;.-sm tind of mak.-Lng tne brain resist&-,,.t special extreme conditicei~~. There are 3 vigmettes. ASSOCIATIONa Otde'----~nLye n,--uk AN SSSR (Department of of the AS USSR) Card ?/2 8/025/61/000/011/001/00,A D243/1130? AUTHOR*, aisakyan, N.M., Academician TITLE: Biochemistry and Space PERIODICAL& Nauka i zhizn', no. 11., 196% 50-53 TEXTs This is one of a group of articles on the 5th lntern,~,- tional Congress of Biochemistry and deals with the contribution biochemistry may make to space science and 7ice versa. The im- possibility of carrying sufficient food on a prolonged space flight wili necessitate the establishment on board cf closed, esolo&ical. systems to feed the astronaut- This idea. of K.E- Tsicl- kovsky involves using human and animal. waate to grow plants, with which to feed the travellers. The sinGle-celled alga, Chlorella, is likely to be of great importance in this connection due to its rapid multiplication, need for little attention, ability to utilize solar energy and the physiologically valuable materials Card 1/'2 S/025/61/000/011/00,!/00'.2 Biochemistry and Space D243/D302 it Contains. "Josmic flights may help to solve the problem cf extra-terrestrial. iife. Arrhenius's Panspermism Theory and nb-- jections to it are discussed. An article by Academician A,I. Opa-, rin in the ~;urrent journal is mentioned. This question. is ~~lose ly linked wit-ft tiae study of the biosphere, _-be6un by r' T.I. Vernadskiy, the lower limit of which has beer. established" already at !0-11 kilometer below sea level., but the upper Iiii-r--it of which is still unknown. The existence is postulated of a zone in the Solar System where conditions are suitable for .' he existence of carbon based living matter- Only Mara, Earth and Venus are in thig zone. Recent observations by Sin'on, +-heor!.44_o of ',`,.Pade~,Acian. Tikhov, ilave Thec-ry, F--om f~o_2-par_i scr of terrestrial and extr-q sl-~, i a'- f orr-'C~ i~ f life a_-_d of adaptation of the former tc 4'.'ne entijr-_~nm=ln' in parts of tae sol.Lir systew it may be possibl-_ 'c law of life in. the Universe. Card 2/1 SISAKEMI, N. M. [Sisakyan, N. M.] Biochemical functions of cullular structures. Analele biol 15 no.6: 27-54 N-D 161. SISAKYA11, N.M., akademik Ilan strides into the space. Sov. profsoiuzy 17 no.14:27-30 il 61. (MIF-k .14:7) (Space biology) I SISAKYAN, N.M. (Moskva); GAZEITKO, O.G. (L'Aoskva); GENIIN, A.ML. (Moskva) Some problems of space biology. s-o 61. BIOLOGY) Zhur. ob. biol. 22 no.5:325-132 (KRA 14:9) (SFAGE MOSOLOVA, IJI.; SISAKYjIN, N.M. Condition enabling the isolation of mitochondria frcm plant cells. Biokhimiia 26 no-3:549-555 My-Je 161. (MIRA 14:6) 1. Institutb of Biochemistry, Academy of Sciences of the U.S.S.R., Moscow. (MITOCHONDRIA) (PLANTS;.;.-CHEMICAL ANATISIS) SISAKYAN, akademik - sekretarl ---- ------- -- Toward the 22d Congress of the CPSU. Izv. Ali SSSR. Ser. 26 no.5:657-663 S-0 161. OUIRA 14: 9) 1. Otdeleniya biologicheskikh nauk AN SSSR. (BIOLOGICAL RESEARCH) SISAKYAN, KALACHEVA, V,Ya. Action of X-ray irradiation on oxidizing phosphorylation in plant mitochondria. BiokhizLiia 26 no.5:877-881 S-0 161. (MLqA 14: 12) 1. Institute of Biochemistry, Academy of Sciences of the U.S.S.R., Moscow. (PHOSPHO.uLAT loll) (KITOGHOIDDRIA) (PUNTS , EFFECT OF RADIOACTIVITY ON) iv, r nrl "J1-1.1' A A -'.16orly ok oo c, tilt CW, Myorjiysio . SISAKYANU , I'lorayr M-a-ft4os-ovich, alcademik Man in orbit. Tekb,mol. 29 no.5:16-17 161, (ITURA 14: 5) (Astronautics) .7 SISAKYAN N.M.,, akademik; RUBANIK, K.F., kand.yurid.nauk Some problems in international cooperation in science; results of the llth session of the general meeting of UNESCO. VestAN SSSR 31 no-5s78-88 Yq 161e (MIU 14:6) (Science-International cooperation) 23454 S/'030/61/'000/006/005/014 27,9-00 0 tlo"2' B101IB206 AUTHORi Sisakyan, N. M., Academician TITLEs Biological problems of cosmic flight PERIODICALg Akademiya nauk SSSR. Vestnik no. 6, 1961, 31 - 40 TEXTs A survey of the development of cosmic biology is given on the occasion of the flight by Yuriy Alekseyevich Gagarin on April 129 1961. Five stages are distinguishedg (1) Exploration of the upper atmosphere by means of rockets; (2) biological research on animals in heights from 100 to 450 km; (3) investigations by means of satellites, assurance of telemetric communications '4) recovery of animals used for experiments; (5) flight of a human bping. Overload and weightiessness had no detri- men-ca.L eiiecz, rne v.Looa circulation was not disturbed. The effect of ionizing radiation is not clarified yet, since the flights carried out so far were made below the radiation belt. The voluntary pilots were examined clinically and psychologically, trained under flight conditions, and instructed in landing, control and radio cummunications. The following Card 1/4 23454 S/03o/61/000/006/005/014 Biological problems of cosmic flight BIOI/B206 data on Gagarin'sQflight are given% Inside cabin pressure 750-770 mm Hg, temperature 19-22 0, relative humidity 62-71%. Cardiac and respiratory reactions of the pilott 50 min before startR pulse 66, respiration 24; 3 min before start5 pulse 109, respiration unchanged; at starts pulse 140-158, respiration.20-26, after start: pulse 109~ respiration 18; during the state of weightlessnesss Pulse 97, respiration 22, No inhibition of the capacity of action. Short-time increase of respiratory frequency during landing, but only 16 during approach to the ground. 3 hr after landing% pulse 68, respiration 20. The following future problems are mentionedt (A) Effect of cosmic factors% (1) Mutations under the effect of radiation. The possibilityof using the cosmic factors for selection in mentioned. Problem of cell division during the state of weightlessnean. (2) Protection againot proton radintion by the inner belt. (3) Use of solar radiation for the energetics of the space ship. (B) Bio- logical problems. (1) A calculation yields the following datat daily requirement of 02, H20 and nourishment of a human being 3500 g. This makes 19 t for 5 persons and 3 years. (2) This shows the necessity to establish a biological cycle in the cabin by using solar radiation- Card 2/4 23h5h S/0-30/61/000/006/005/014 Biological problems of cosmic flight B101/B206 (a) complete water cycle distillation, electr-aasmosis or exchanger resins) can be achieved; ~b) 0 2 eyelet photolyti-c decomposition of CO 2 by means of hard ultraviolet on a copper catalyst; electrolysis (or pyrolysis) of the metabolic H 20, interaction of H2 with CO2 under forma- tion of HCOH and 02' Utilization of anaerobic bacteria which adsorb H 2 and CO2 and eliminate 0 2' (C) Regeneration of nourishment and products of vital action. Complete synthesis from inorganic substances is still a theory. More possible is a cycle corresponding to the natural cycle on the earth. The photosynthesis by unicellular algae, the nutritive value of which is investigated at present, is discussed. The psychological effect of nourishment must, however, also be taken into calculation, so that the carrying of plants and animals is to be considered. (3) Forms and conditions of life in the cosmos are still hypothetical. The existence of organisms has not been proved with certainty yet. The problem of the possibility of existence of terrestrial forms of life and their adaptaticn to living conditions on other planets is mentioned, as well as the uncontrolled transfer of terrestrial microorganisms to other planets Card 3/4 SISAKYAN, akademik The Pugwash meetings of scientists. Vest. AN SSSR 31 no.11: 81-84 N 161. OURA 14: 11) (Science--International cooperation) POSPELOV) P.H., akaderaik; MINTS, A.L. , akademik; AIZKSAI-TDROV, A.P., akademik; FEDOSEYEV, P.N., akademik; LAVRENITIYEV, M.A., akademik; BERG., A.I., akademik; FETROVSKIY, I.G., akademik; SIDOF,?NKO, A.V.; SKRYABIII, G.K. , kand.biolog.p-auk; KONSTtNTIN011, B.P., akademik; GOLUIISKIYI S.A.; SIIUBNIKOV, A.V., akademik; BLOKHILITSEV, D.I.; DORODNITSYN, A.A., akademik; MROV, B.M.; SISAKYAN, N.M., akademik DiSOUDUIDg thO I'OpOrtS, Voot. All SSSR 31 no.12;49-66 D 161. (14TRA 1l,: 12) 1. Chleny-korrespondenty AN SSSR (for Sidorenko, Golunskiy, Bloldiittaev, Kedro7)-. (Research) SISAKYA-N, 9,,M, akademik The way to space is open. Priroda 50 no.5:6-7 My 161. (Astronautics) (MM 14:5) - I,-. 'L, Im'. A.; ~ 61 8-'I:.Y 1%. ~. s -k-dumil: .1 3 j ,.u-clz:otJ-.de compoaition o~ rtcl;jic acids in some ins ct --* .-I ~ Doll. -17 SS3R 1W no. 1.206-~'-lr,9 I-Dr-Ap 161. (*;-1;.;. 14: j (In ects-Phyoioloaj) (Ilucleotides) SISAKYkNp NaM, (McAva) Biochemical functions'.of cellular structures. I'sp. sovr. biol. 51 no. 2:129-152 Mr-Ap I I (~MRA- 14:4) . 1( Cv METABOLISM) SIO;201611"141100310211021 B103/B101 AUTHORS: Sisakyan, N. M. , Academician, Bezinl-,er, E. N. , and lfarchukaytk6 TITLE; Participation of plastid lipoids in protein synthesis PERIODICAL: Akademiya riauk 53SR. Doklady, v. 141# no. 39 1961, 748 - 750 TEXT: The bond between lipopeptide and protein molecule was studied to prove directly its participation in protein synthesis. Lipopoptides are located in cell structures where protein synthesis takes place. Hence, lipopeptides are assumed to participate in protein synthesis. Chloroplasts were isolated from 200 - 250 g of young bean leaves (Phaseolus by fractionel- centrifuging with 3WOg of saccharo3e phosphate buffer (PE 7.11 at a maximum of 3 - 40C. They were ground in a homogenizer in 20 milliliters of the ' buffer, and incubated in the presence of Mg2+ ions at room temperature and a -'ff of 7-0. 0.25 milliliters of glycine-1-C14 solution (corresponds to . 328,r)00 imp/min) and 1 milliliter of chloroplast suspension were added to each sample. The inclusion was periodically interrupted by addition of 0.01 milliliters of 10% HCI (pH-/I) and rapid cooling. Before adding a suspen- Card 1/3 SION1611141100310211021 Participation of plastid... B100101 sion, RCI was mixed with the control samples. After incubation, the test tubes were centrifuged the deposit was washed with water and extracted three times with a 75% alcohol (up to a PH of 4, acidified with ECl). Thus, the lipoproteid fraction was obtained from plastids. The following fractions were obtained: I'lipoid I", "protein Ill, and "protein II" whose radioactiv- ity was determined. Under the above-mentioned conditionsp glycine-l_cU was found to be included almost simultaneously in the lipoid and protein parts of lipoproteid. At a PH of 5.8, the inclusion of radioactive label in the lipoid part is independent of Mg 2+ whereas this inclusion is 1 2+ completely missing in the protein part without Mg . Thus, it was shown that amino acids in Isolated plant plastids were included in proteins with active participation of lipoids bound to proteins. Besides nucleic acids, lipoid substances are also assumed to tAke part in the activation and tra--.8- port of amino acids. Their participation howeverp can be of a different nature; thus, especially lipoids may take oart in the regulation of per- meability processes. The studies are beir.1 continued. There are I figurep 2 tables, and 20 refererices: -12oviet Ln6 11 non-Soviet. The three most recent references to Eng1ish-1-,--.-1.i-we publications read as follows% G. B. Hunter, R. A. Goodsall, 1., _76. Ll,~,j (iq6i); T. Fukuiq B. Axelrodo Card 2/3 I Participation of plastid ... Fedorat. Proc., 19, 6 (1960)1 811 (1961). SUBMITTEDt August 23, 1961 Card 3/3 S/020/61/141/003/021/021 B103/BIOI T. Pukui, B. Axelrod, J. Biol. Chem.9 Wk. 0 -. TATARSKAYA, R.I.Prinimali uchastiye: YIALYOVA, M.G.; KOSAREVA, Ye.A.; SISAKYAI~, NXI., akaderik, glav. red.; ENGELIGARD, V.A., -,ka- ----a-eMi-R-,red'-. toma; 7-17ROVA, I.B., red.; POIYAKOVA, T.V., tekhn. red. (Biological structues and functions at the molecular level; symposium IjBiologicheskie struktury i funhtsii na moleka- liarnom urovne; simpozium. 1. Moskva, Izd-vo Akademii nauk SSSR, 1962. 298 p. (Its: Trudy) (MIRA 15:12) 1. International Congress of biochemistry. 5th, Moscowo 1961. (BIOCEEMISTRY-CONGRESSSES) L-ce.; -77 C"'-adendk, red. tcra; VETHOVA, I.D., , , ~ ; M-RE., , !. p red. izd-va; NOVICYOVA, N.D., tekhn. red. [Transactions of the Fifth International Congress of Bio.- chemistry]Trudy V Nezhdunarodnogo biokhimichoskogo kongressa. Moskva, Izd-vo Akad. nauk SSSR. [Vol-4. Evolutionary bio- chemistry; symposium No.3.]Evoliutsionnaia biokhimiia; sim- pozium 111. 1962. 350 P. (MIRA 15:10) 1. International Contress of Biochemistry. 5th, MoEcow, 1961. (BlCCIMMISTRY-COGRESSES) POLYANOVSKIY, O.L.; TORCHINSKIY, Yu.M.; Prinimall uchastiye: MALKOVA, M.G.; KOSARFVA, Ye.A.; -SISAKYAN, 11-11-'-akademk, glav. red.; BAYEV, A.A., zam. glav. red.; BRAUNSHTE-171, A.Ye., red. toma; VETROVA, I.B., red. izd-va; ZUDIIIA, V.I., tekhn. red.; DOROKHINA, I.N., tekhn. red. [Molecular mechanism of enzyme action and inhibition; symposium 41 Molekuliarnye osnovy deistviia i tormozheniia fermentov; simpo- zium IV. Moskva., Izd-vo Akad. nauk SSSR, 1962. 361 p. (Its: Trudy) (MIRA 16-2) 1. International Congress of Biochemistry. 5th, Moscow, 1961. 2. Chlen-korrespondent Akademii nauk SSSR (for Braunshteyn). LEVIN, F.F. Prinimali uchastiye: N,1JZOVA, M.G.; KOSAREVA. Ye.A.; SISAKYAN, N.M.~ akademik, glav. red.; UTEV, A.A., zam. glav. jed'q PASOVSKIYp A.A. 1.E., rW,. Ind- Va; D~IWPOA~ I.N., tekhn. red. [Mechanism of photosynthesis; symposium VI]14ekhanizm foto- sinteza; simpozium VI. Predsedateli: Kh.Tamia (IAponiia), A.A.Krasnovskii (SSSSR). Moskva, Izd-vb Akad. naak SSSR, 1962. 386 p. (Its: Trudy) (MIRA 16:1) 1. International Congress of Biochemistry. 5th, Moscow, 1961. 2.Chlen-korrespondent Akademii nauk SSSR (for Krasnovskiy). (Photosynthesis~Congresses) KREKHOVA, N.A. Prinimali u(.-hastiye: MALKOVA, M.G.; KOSAREVA, Ye.A.,- SISAKYAk, akademik, glav. red.; BAYEV, A.A., zam. glav. id- r ,- YUDAYEV, N.A., red. toma; VETROVA, I.B., red.izd-va; DOROKHINA, I.N., tekhn. red. [Biosynthesis of lipids-, symposium VII]Biosintez lipidov; simpozium VII. Moskva, Izd-vo Akad. m&uk SSSR, 1962. 429 p. (Its: Trudy) (MIRL 16:4) 1. International Congress of Biochemistry. 5th, Moscow, 1961. 2. Chlen-korrespondent Akademii meditsinskikh nauk SSSR (for Yudayev). (Lipids) MASLOV, S.P. Prinimall uchastiye: MALKOVA, M.G.; KOSAREVA, Ye.A.; SISAKYAN N . akademik, glav. red.; RAYEV, A.A.,, zam. !F:e~RIN, S.Ye., red.toma; VETROVA,I.B., red. i izd-va; GUSEVA, A.P., tekhn. red. (Intracallular.respirstion: phosphorylating and nonphospho- rylating oxidation reactions; symposium V]Vnutrikletochnoe dykhanie: foaforiliruiushchie i nefosforiliruiusive-ble re- aktsii okisleniia; simpozium V.Moskva, Izd-vo Akad. nauk SSSR, 1962. 439 p. (Its Trudy) (MIRA 16:3) 1. International Congress of Biochemistry.5th, Moscow, 1961. 2. Chlen-karrespondent Akademii nauk SSSR (for Severin). (CRLL WTABOLISH) (PHOSPHORYLATION) KOSLREVA T V - LISOVSKUA, V.P.; MAMOVA, M.G.; Ye. A.; SISAY,Yffllj_ 14. -1 akademik,, glav. red.; BAYEV, A.A., zam. glav. i'-ecT.-; VWROVA, LB., red. izd-va; GUSEVA, A.P.j tekjm. red. [Transactions of the Fifth International Congress of Biochemistry] Trudy V Mezhdunarodnogo biokhimicheskogo kongressa. Moskva Izd-vo Akad. nauk SSSR. (Vol.11. Sectional reports; sections 14-281Refe- raty sektsionn-ykh soobshchenii; sektsii 14-28. 1962- 581 P- (MIRA 15:10) 1. International Congress of Biochemistry, 5tht Moscowp 1961, (BIOCEEMISTRY-OONGMi~ES) SISArM, 1. M. N Contributions to the 301wation or Spao*." report to be, submitted ror the International Symposium an Basic Invironmental Prob2ame or Men, In ftace.. (10)., Paris., hmmm., 29 Oct - 2 ftv 62 SISAKYAN, N.M.; PARIN, V.V.; CHERNIGOVSKIY, V.N.; YAZDOVSKIYl, V.I. Some problow of studying and conquering outer space. Probl. kosm.biol. 1:5-16 162. (MIRA 15:12) (SPACE BIOIDGY) SISAK,YAN,.-X,-N,-; GAZENKO, O.G.; GENIN, A.M. Problema of epace blologv. Frobl.kosz.biol. 1:17-26 162. (KRA, 15A2) (SPACE BIOLOGI) SISAKYAN) N.M.; BEZINGER) E.N.; SHAPOSHNIKOVA, M.G. Amino acid composition of Chlorella pyreudoidosa. Probl.kosm. biol. 1017-376 162. (MIRA 15:12) (ALGAE AS FOOD) (ASTRONAUTS-NUTRITION) (MaNO ACIDS) S/216162/000/002/001/002 1021/1221 AUTHOR: Sisakyan, N. M., Parin, V. V., Chernigovskiy, V. N. and Yazdovskiy, V. 1. TITLE: Problems of space biology and physiology PERIODICAL: Akademiya nauk SSSR. Izvestiya. Seriya biologicheskaya, no. 2, 1962, 153-162 TEXT: Lecture at the General Session of the Department of Biological Sciences. The article deals with space biology and physiology in the USSR. Although a young science, it has already created new methods of biological experimentation, realized autornaticaMy by special devices installed on spaceships. The results of these experiments are registered and delivered to observation points on the earth. According to the authors, 3 problems are at present of great importance: 1) study of the effects of cosmic fac- tors on living organisms of the earth, 2) study of forms of life in outer space, 3) investigations into the biological basis for securing cosmic flights ind life on planets. The authors outlined 5 periods in the development of space biology in the USSR. The first was connected with biological interpretation of the data on physical charac- teristics of the upper layers of the atmosphere, cosmic space and flights of rockets. In the second period experiments were carried out under conditions near to those of cosmic flight. In the third---experiments were carried out on Sputnik 11. It was demonstrated that life is possible under conditions free from gravity. In the fourth period biological experiments were carried out on spaceships with animals. These assembled the data Card 1/2 Problems of space biology and... S/216/62/000/002/001/002 1021/1221 necessary for putting a man in to orbit. The fifth period was characterized by the flight of man in space. The authors deal further with all factors liable to affect living organism in a spaceship. They divide them into 3 groups; 1) factors connected with the dynamics of the flight-vibration, lack of gravity, 2) ultraviolet, infrared and visible parts of radiation, ionizing radiation, concentration of gases, 3) factors connected with more or less prolonged life of organisms under artificial conditions of a spaceship-isolation, lack of room in the capsule, microclimate and nutrition and rhythm of life. The authors also refered to exobiology. Card 212 SISAKYAN, N.M. Scientific achievu-ments of the institutions cf the Department of Biological Scienceo and their practical aFpUcation. Izv. AK SSSR. Ser. biol. no-3:317-331 MY-Je 162. (MIRA 15:6) (BIOLOGICAL RESWCII) SISAKYA111.1 1.(,6CLOVA) Ill.!. Biocheidcal functions of plant mitochorOria. Izv. AN SSSR. Ser. biol. no.3:-"32-353 14Y-Je 162. (MI-RA 15:6) 1. Institute of E.4ochemistry, Leademy of Sciences of the U.S.S.R., Mosca'.r. (MITOCIIL,I:DRIA) SISAYYAIT, N. M, (IAOSI-va); MELIK-SARYISYM, S. S. (floskva) Proteins in 11:JI), litol~ klilill- 4:*'-".11 (MIRA P,O) (PROTEINS) (GHROMATOPHOU-S) SISAEAN, N.M.; ZDARSHY, I.D. Functional biochemistry of cell stur-actu--es at the FiftL- BiochemicnI Congross. TSitolp"U1, no.2:21,3-247 14r-Ap 162. (141hA 15:8) (CYTOID(ff -CONGPXSSES) SIC26,?621000100710011005 A nev; zhase !~rirodi, no. 7, 1962, 13-15 1EXT: Thi-- ij the fir3t of a series of -articles by participants of the :2'-,iaIInry--i s,-.3siya "Biologiya i kib~!rnetikall (Special Session "Biology ,nd C:,rb--rnr!t'cs'I), convened by the Biologicheskoye otle~eniye AN SSSR (Bio- D-p-trtment of the AS USSR) jointly with the Nauchnyy sovet po kiberne- (Scientific Council for Cybernetics) and other scientists, in which the, -I'Lithor --.~vo~!ates that cybernetic and mathematical mqthbds should be widely ;~-.,ppli-?d in bicloUical research. The use of such methods in biology has 3t-irted litely, but it is too early to sum up or draw final conclusions. initial work has been done in the study of complicated biochemical and bio- pl-.yzic--l phenomena of molecules, subcells, and cells, where the unity-of -Iructure and function makes it possible to penetrate into the essence of t2e most complicated phenomena of living nature. Cybernetic ideas and 11 Card 1/1 3102 62/000/007/001/005 D050YDI 13 -irq -i.-iplied in 'he modern p1hysiology of receptors and rtception. of tho theory or automatic rontrol have found application i~ri ba~3_ic nhys4olog ~icul futiction uontrol. The devolopmfint of mor- or lazzin capable of making dacisions under complex 4uickly-changing conditions is connected -.,rith this problem, the solution of which would per- -it -,rObleM3,such as the automatic perception of speech, the analysis of biclo:lical structures, pilotless cosmic flight, to be automated. A cyberne- tic a-~nroach in the reproduction of some elementary functions of living bAn_-~, ,--ill help combat premature aging, and will assist in overcoming diseases resulting from rh~-thm disturbances in molecular and structural pr_-cesses. The interaction batween cybernetics and biological phenomena isi Card 2/2 SISAKEAN, R.M D.G.; GHENIN, A.M. [Genin, A.M.] _I,___[Sisakyan, N.M.]; GAZENKOIV Some problems of cosmic biology. Analele biol 16 no.2:3-11 Mr-Ap 162. SISAKIAN, N.M., Akademik Theoretical problems of biology sad their importance for agriculture. Kosmos biol 11 no,6:625-636 162. SISAKIAN, N.M.; VEINOVA, M.K. The nature and the biological role of peptides and nucleotide peptides. Analele biol 16 no.6:68-77 N-D '62. SISAKYAN, N.M.; MMOVA, M.K. Nature and biological rolo of peptides and nucleotide peptides. Biokhimiia 27 no.1:173-180 Ja-F 162. (14II(A 15:5) 1. Institute of Biochemistry, Academy of Sciences of tile U.S.S.R., Moscow. (pppn (NUCIEKOTES ) :-%S.; SISAKYAN, - ----L- propertles of ~ytoplasmir prote'ris ar,~ of sc"'S cnicroplast proto-ins in higho~r plants. . Biokhtmita 127 no . r~, -. N-D 162. ( ,va I LA I - -. -5 ) ". Anstit,it binkhimi-i Imeri Bakha AN 339R, Moskva. ~7 MLI UT 1 1 lr~jlaticn and characteriitics of' r1trisom,"s T-. i a 27 no. n: Y ;61-10"() N-D Ez. MI.-tA 17 1. lrnitLra' lbiokllinli brit3ni Bakha AN USSR. Mosklia. MAHAN, N.M., akademik Important stage in the development of present day biochemistri. Vest. AN SSSR 32 no.1-:84-95 Ja '62. (YJRA 1-1-1:1) (BIOUEEMISTRY) SISAKYAN, N.M., akademik Theoretical problems in biology and their importance to agriculture. Vest. AN SSSR 32 no.5:8-19 W 162. (WRA 15:5) (Biological research) (Agriculture) SISAK M v N., akademik Bloliogy and the conquest of space. 162. Av.i kosm. " no.2:2.4-30 (MM 15:3) (SPACE BIOLOGY) ekademik, glav. red.; ROSTOWSEV, V.F., ak-ademik, zam. glav. red.; BTjKJII, V.N., zasl. deyatell nauki i tekhniki RSFSR, doktor biol. nauk, zam glav. red.; NOWOV, I.Ye.., akader-,ik, red.; YCHASILINIKOV, N.A.., red.; RAKIT.IN, Yu.V., red.; OVSYANNIKOV, A.I., red.; SWANEITKOV, V.A., doktor sellkhoz. nauk, red.; SAVELIYEV, I.K., hand. sell- khoz. nauk, red.; KOCIIEREZHKIN, V.G., kand. biol. nauk, red.; MIKHLDI, E.D., vod. red.; KOLPAKOVA, Ye.A., red. izd-va; iffLINA, Yu.V., tekhn. red. [Problems of increasing the use of chemicals in animal husbandry; using biologically active preparations] Voprosy khimizatsii zhivotnovodstva; primenenie 'biologicheski ak- tivny1ch preparatov. Sbornik rabot. Moskva, Izd-vo, AN SSSR, 1963. 303 P. (M-RA 17: 1) 1. VseBoyuznaya akader-_iya sellskokhozyaystvennyl--h nauk i1r.. V.I.Lenir4. ;~. Vsesoyuznaya akademiya sel'skokhozyaystven- nykh nauk im. V.I.Lenina (for Rostovtsev, Moz9ov). 3. Chlen- korrespondent AN SSSR (for Krasillnikov, Rakitin). 4. CILIen- korrespondent Vsesoyuznoy akademii sellskokhozyaystvennykh nauk im. V.I.Lenina (for Ovsyannikov). (Stock and stockbreeding-Feeding and feeds) (Agricultural chemistry) STSAKYA11 11 14 a1cademik At a new stage. Friroda 51 no.7:13-15 Jl '62. (MIRA 1-11:9) (Information theory in biology) GUMIUVSKkYA.9 N.A.;_~~ akademik Presenge of pseudouridylic acid in the ribonucleic acid of insects. Dok.1.AN SSSR I" no.1:223-225 My 162. (MIU 15:5) (Uridylic acid) (Nucleic acids) SIBAKYAIII II.M.. akademik; GLADILIN, K.L. Adenosinetriphosphoric acid and protein synthesis in chloroplasts. Dokl.,U,l SSSR 244 no.2:453--450' W 262. OMPA 15:5) 1. Inatitut biokhimii " A.N.Bakha AN SSSR. (ADE NOS INETRIPHOSPHORIC ACID) (PRCTEINS) (CHLOROPLASTS) SISAKYAN, N.M.., akademik,- FILIPPOVICH, I.I.; SVETAYLO, E.N. Participation of chloroplast ribosomes in protein synthesis. Dokl. AN SSSR 147 no.2:4.88-1+89 N 162. (MIRA 15: U) 1. Institut biokhimii im. A.N. Bakha AN SSSR. (PROTEIN METABOLISM) (CHR(VATOPHORES) VMOVAP M.K.; SISAKYAN, N.M.... akademik Inclusion of tagged amino acids and adsnins,4~~4 in nucleotide peptides of baker's yeast (Bacch. cerevislas). Ml. AN SSSR 147 no.3t731-734 N 162. (KMA 15812) 1. Tmatitut biokhimii im. A.N. ]blrhn AS SUR. (MaNO ACIDS) (AMMINS) (PIPTTME) SISAKYAN N. M., akademik: BEZINGER, E. N.; MARCHUKATTIS, A. S. t%reukaitis, A.] Role of chloroplast lipoproteids in protein OntheBiv. Dok:L. AN SSSR 147 no.6:1493-1A.94 D 162. (MIRA 16-1) 1. Institut biokhimli Im. A. N. Bakha AN SSSR. (chromatophores) (LipoDroteins) (Protein metabolism) SISAKYAN, N., akademik Electronics in biology. Radio no-5:3 W 163. (MM 16:5) (Electronics in biology) SISAKYAN MC.; RODOPUW, A.K.; YD.,OROV, I.A.; SARISHVILLI, N.G. -- Products of the transformation of amino acids by yeasts and their ekfect on the quality of champagne. Biokhim. vin. no.7.131-147 163. (MIRA 16:4) 1. Institut biokhimii imeno A.N.Bakha AN SSSR i TsN]LLViSV Ministerstva sel'skogo khozyaystva SSSR. ,o, (Champagne (Wine)) (Amino acids) SISAKYANY N.~L~ YxLOROV, L.A.; BIMUZIE, G, L -- ]CiANTALIAN1, N. " methods for improving +,he quadlity of cognac,, Oiokbin v-lau zp.7,. 164-172 163. (ICM 16:4) 1,, Institut, bicjkhijaii imeni A.M,Hakha AN SSSR i Institut eadovodstva, vinogradarstva i vinodeliya Gxuzin.,ikoy SSR+. (Brandy) SISAKYAN, N.M.; ICLIK-SARKISYAN, S.S. Some characteristics of the proteins of photosynthesizing~~md nonphotosynthesizing plant palstids. Fiziol. rast. 10 no.l.-17-22 Ja-F '63. (MIRA 16:5) 1. A.N.Bakh Institute of Biochemistry, U.S.S.R. Academy of Sciences, Moscow. (Chromatophores) (Proteins) SISAKYAV, N.M.; KOBYAKOVA, A.M.; FILIPPOVICH, I.I. Adenosinetriphosphatase of protoplasmic structures in plants. Biokli-imiia 28 no.6:1011-1017 N-D'63 (MIRA 17:1) 1. Institute of L-"(- , Academy of Sciences of the U.S.S.R.J# Moscow. SISAKYAN, N.p alcademik Present state of and -the outlOOk for the smace. biolo AV i kosm. 45 no.1:10-15 N o5ye 0 Ja 163. IRA 16:1 (Space biology) SZISZAKJAII, N. [Sisakyan,, 11.] The nev epoch of biology. Magy tud 70 no,6/7~468-470 Je-J1 163, GUMILEVSKAYA N.A.; SISAKYAN, N.M., akademik Comparative study of the nucleotide composition of microsonal and soluble RNA in insects. Dokl.AN SSSR 149 no.1s198-201 Mr 163. (MBA 16s2) 1. Institut biokhimii im. A.N.Bakha AN SSSR. (Nucleic acids) (Insects) GUMILEVSKAYA, N.A.; SISAKYAN, N.M., akademik Difficulties in determining the nucleotide composition of total RNA in insects. Dokl. AN SSSR 149 no.2:450-452 Hr '63. (MIRA 160) (Nucleic acids) (Nucleotides) SISAKYANI N.M., akademik; BEZINGER, E.N.; YOLCIIANOV, M.I. ""- gffect of puromycin on the incorperation of amino acids into lipoids and proteins of chloroplasts. Dokl. AN SSSR 151 no.2: 449-451 Jl 163. (KRA 16:7) 1. Institut biokhimii im. A.N.Bakha AN SSSR. (PuroWcin) (Chromatophores)