SCIENTIFIC ABSTRACT ZHDANOV, A.A. - ZHDANOV, V.H.

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SCIENTIFIC ABSTRACT
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U49SE SMONOVA, ff. A., et al., Gigiyena Truda i.Profession'allnyye Zabolevaniya, No 9, SeP,71, pp 46-48 examination (frontal and lateral chest x-ray pictures and tomograms., the median layer and layers 2 cm in frontand.behind it),. An x-ray of the thorax .18 hro after phosgene intoxication is,shown. The frontal x-ray picture had a shadow running parallel to and 2-8 mm avay.from the left heart contour. Ko~otber changes were found in the lungs. The heart boundary.was no, 1. At-that time, the x-ray picture taken 18 12ours.after the accident was reexamined: it also contained the linear sbadow running parallel to the heart. It was assumed that, a pneummediastinum had developed. The linear shadow was believed.to xvipresent parietal pleura dis- jilaced by air. The picture corresponded to;data, despribe& in literature (A. I. Dombrovskiy; G. A. Zedgenidze and.L. P. Linde4ibraten). On the ninth day, the patient,had no complaints, his cough subsided, dIrspnea developed only during physicrJ. exertion, tbere were no pulmonary noises, and the subcutaneous emphypeiial vase no longe.r! felt. His pulse was Un 1e, fluctuating from 64 to 120 baatsperminute. EKG was normal with no sigw of right heart dilation. The linearshadow aloilg the left heart edge was no longer present on x-ray.,~pictureo,.vhich,..conf.irmedithe previous diagnosis of pneumomedihst.inum. On the 25th,day, the patient was discharged from the hospital in good 6ondition. 4/4 Acc. Nr. Abstracting Service., Ref. Code M0048844 CHEMICAL'ABSTO P 9104lq Determination of the Comilo L-Of the reaction mixture in the polymeriziltion: of organoc.~cl xanes by osila. Infians of onlatograp y. ~ Andrianov. i. A.; ZLidanov, A-, -get chr h Zavin,' B. G.-_ Sunekants, M I I. FI -f- - LLnst ernentonrit Noedin., A ~,S~) - Sovdin-, Ser. A -l9W)-,T2(j)' 20-5 (Russ). The contents 'of high b.~.. Iow n~ol. Nvt.~Ioraano6,closilox- anes; (present in a inixf, withipolyrners), eg.,~octaphenylcycjo- he tetrasiluxane, nAen~10.clotq~aoxane' l,:i.5,7-tetrarnethyl_ 1,3,5,7-teiraphen~IcYc)6ietrasilt)i one (1). 1_1,5,5-tkrainetkyl- 4- 3,3,7,7-tet rap henvic~06wMsi 16 xi fie (11), 1.1,3_5,~7-peqtamethyl-, 3.5,7 he~.amethyl- 7,, - diphenylcyclotetiasiloxanei 1,3.5 - trimethyl 1,3,5 -'triphenyl- ;~?clotrisiloxane,- ~ hepta met hylphonyl 6 clot etms i loxa n e, octa- me thy1cyclotetrasiloxane (11]l)i~ h~iameib~ltrisilowane,:I'errocene, hexa met hyldisifoxA ne., and ~ SKTV-1 poly(aimethylsiloxane) rubber (mol. wt. 450,000) were studied by~gel chr~rnatog The dis- tribution factors ~ (K,,) ; were calO. from eNtion 11.1s. (V') ('-,CHG eluent t). The K, and were inversely proportional to the mol. wt., e.g.,-! and-Whid- identical V," nd &~ Elution j of SKTV-1 and HI on a 96:4 styi~efie-d i'liny . ezene copo ymer gave- satisfactory results and ~w~ ~hjghl~. T e p ripo' vcible:~, A good M.m correlation was obuirted between' I ch. atqgj;'and griavimetric anal, of Ell. A rAid betweeri 1 6 rorn to apitic petilis gave a a good indication of monomer conus tion tin pjAymn. du CKJR ....gEEL/FRAME 198" OG11:1 UDC 678.84.01:537 USSR BAZENOVA, T. S., MOON, V. I.,,~ jjD=V4,A. A., POLYAKO.VA, L. L., OV, e. -SMIRNOVAj L. N., EKSANOVA, N..D~~, and TAW "Electric Properties of the Epoxyorganosilicon Resin:ES-9 and Compounds 'Based on This Resin!' Moscow, Plasticheskiye Massy, No 2, 1973, pp 21-23 Abstract: Results are reported of the study of electric properties of the compounds based op. dianic resin ED-5, polyfunctional resin ETF and epoxy- siliconorganic resin TPE-9 containing triphenyl penLaiftethoxytrisiloxane! (resin ES-9). It was shown that the ES-9 resin is a good, active solvent for compounds based on any epoxy resin prepared for-clectrotechnical utilization. The ES-9 resin lowers considerably the starting viscosity of the epoxy binder preserving:at.the same:.time al1of tha desired electric properties of epoxy compounds b6th-under normal usage as well as during prolonged heating, increased humidity,.1and elevated' iic!nperature. -61- 03:7, Infoinhation-Th6 USSR U0 553.9.0d ZHDANOV, A.I., NES7ZMAO, P.T., MUROV, A.F., GOLOSINY41 V. L. "Automation Of Analysis Of Experimental Data In Investig0tiono Of Plasma Physics" Vestn. Khartkov. nolitelhn. in-ta (Bulletin Oflharlkoy Polytechnical Institute), 1970,- No 50(98), pp 55-56 (from, RZh--Slektr2.n'k imeneniye, No 1, k a iyeye L) January 1971,Abstract No 1A236) Translationa A system is described~whiqh is intended fo.r automation of the on- alysis of the siantils of diagnostic data units. [AaT14HJCj recorded on a photo- graphic film in experiments of plasma physics. This syatOui, conatructed on the base of the nDnepr" controller, includes q spqcially developed device for intro- information. 3 ill* duction into the machine of graphic ref. Summary. USSR QDC 535.9.08:681.3 10V, V. G. KLBT.0, N.F., DMV fANk nComplex Application Of Analog And Digital Computers In Investigations Of Plasma Physics" Vestn. Kh3r'kov. politekhn. in-ta(balletin OP Kharkor Folytechnical Institute), 1970, No 50(98), PP 57-63 (from RZh--Elektronika i yey6 priinvusniye No 1, Jamary 1971, Abstract No 1A257) Translation: A description Is presunted of an anolog cozplux assembled on the base of the IMN-7 computer series. Problems inveutigatedt on such EL complex are briefly described. In addition, the possibility is considered of nodeling equations in partial derivatives with a combined use 6f,a similar complex and the "Dnepr" controller. 7he results confirmed the posaibili$5, of,an investigation of nonlinear processes in plasma which are described,with ~he aid of equatione-in -Euler variables. Instances of the use of-such a complex ara'anumerated. 4 ill. 6 ref. Summary. -621.039.61 USSR 11DC 533.92 VOIYTSENYA, V. S:, ZISER, V. Ye., DIKIY, A. G., -T- PINOS, I. B., YAROKER, Ya. N. "Calculation and Modeling of Helical Windingp ofVariou's Types on Toroidal Surfaces" Fiz. plaimy i probl. upravl. termoXader. sinteza~,Resp. mezhved. sb. (Plasma Physics and Problems of the Controllect.Thi--rmonuclear:Fusion. Repub lic Interdepartmental Collection) j972 j!,No.; 3, PP 137-1141 (from RZb-Fizika, No 11, Nov 72, Abstract No 11G276) Translation; The problej, of the possibility of using various winding patents for helical conductors on toroida*1 surfaces is investigated: geodesic lines, lines of constant inclination to the generatrix of thia torus, and lines of a cylindrical nnd toroidal spiral. It is shown tbat: a 04;ht clat;t1c, grid can be a fairly good approximation for geodesic lines oil a torus. Data are given for constructing a geodesic line oil a tor.bidii1:9urf-'ace io,ith an arb1trary aspect ratio.. The calculations were made.on.the 'Vral-4," and '4,ir" computers. USSR UDC 54.7-11118+541-124 -KIREYLVA, A. Ya.~ ZHADANOV, B. V., SIDOFMKO, V. V;, and DYATLOVA, 11. M., -Carboxypethyl-N,N-bis "Synthesis and:Study of the Acid Dissociation ot. 1 (hetbylenephosphonic) Adid" Leningrad, Zhurnal Obshchey Khimii, Vol 43, No 11, Nov 73, pp 2508-2511 Abstract: N-Carboxvmethyl-N,N-bis(methylenephosphonic) acid HOOG142CN.(CH 03H2)2 2~ (I; H L) was synthesized by the interaction'~Of-glycineq f6rmalin, and phos- phorous acid in the presence of HC1 (cf. K. Mbedritzer and R. R. Irani, J. Org..Ohem., 31J. 1603 1966). The distribution of various dissociated forms H H20-, jjL4- 07 1 Ij I in relation to the IN a' pH 1-12 was of H5L 113L~, 'studied by IR spectroscopy. On the basla or~the data obt6lined,: a mochanism of the dissociation of I is proposed. 1A 'USSR h AKHMIOV, S. A. , ZIIDANOV B. V ,KOVRIGIN, A. I., and PERSHIN, S. M., Mosc State University onosov, Effective Stimulated Scatteriug::in the~Ultraviolet R~ojjion ;oJ, the Spectrum and in Gain in the 0. 26-1.067-HiCrO4 1whitt!" Moscaj, Pisraa v Zhurnal 13_,Itsperimental'noy,i Teoreticbeskoy. Fiziki, Vol 15, iNo 5, 5Mar 72, pp 266-269 Abstract: Effective induced Reman emission end Mandelotam-Brillouin scatter- ing were obtained in the UV revion, and some ebaracteristics of the two types of scattering were studied. An.increase. in Raman susceptibility in the UV region made it possible to create~an eff,ective Raman Ilquid-~nltrogen laser with-puPping at A, - 0.26 micron (at, 4 putnpin~,:po-,,rer o i,.10 kw. In a syrtem with- out mirrors it was possible to excite, Stokes aeneration. with an efficiency 7 reaching. dozens of percentage pdiz~ps). A marked increase in gain in Che UV region uras also recorded Zor stim6lated Mandolstam-Brillouin scattering. The exciting radiation was obtained from a stable fourth-harmonic -raror witli one longiLudiral and orle ~ tranrjvcrse~, modk. The use of a cascaded system permitted simultaneous Unimode radiation at Xl.-~ 1.06 microns, A 2 -tin factor for A 0 26 micron. The gz .0.53 micron, X3 0.35 micron, and '4, 112 USSR AKW.MNOV, S. A., et al., Pisma vZhurnal Eksperimental'noy i Teoreticheskoy Fiziki, Vol 15, No 5, 5 Ilar 72, pp 266-269, stimulated Ra-man scattering in the U11 region was measured in a parallel bex-i, and a difference was found in the charat ter 6f the gaiii curvo-9. Threshold over values as wel, as threl';l1old Pumping p were measured-for the Mnan laser. nergies for stimulated M.4ndelstam-Brillouin back-sciLtering i-.) pumping crystal and fused quartz. The Irarquency,dependence of~ threshold r-haracter- -istics --id the character of the light break-dmn in c*stal and fuzed quartz and ADP were studied. The.authors thank A. Z. Grasyuk for providing the cr~oi;tat, and L. Pavlov and-V. 1. Kuznetsov for their assistance in the experiments. 2 /2 ~i E ASS PROCESSING. DATE-.-27NOV70 114 02 5 UNC L *1 TJTLE--PROSPECTIVE PL AN FOR DEVELOPMENT OF Of CAL S'Clc ~E' IN THE USSR IN ~'1971-1975 -U-. ,.:AUTHOR-(02)-KOVANOVj V.V.t ZHDANO _D.A.~ COUNTRY OF INFO ISSR SOURCE_-VESTNIK AKADEMII MEDITSINSKIKH NAUKISSSRt VOL 25'9 NO 6v 19TOY iPAGES 50-62 'DATt PUBLISHED ------- 70 4.5,UBJECT AREAS--BIOLOGICAL AND MEOICAL SCJENCESv BEHAVIORAL AND SOCIAL ~SCIENCES NT, PROPHVLAXISI, DIAGNOSTIC -TOPIC TAGS---4GOICAL SCIENCEP DRUG TREATMG 14EDICINE, FIVE.YEAR PLAN, VIROLOGY, MEOPLASMt CARDIOVASCULAR SYSTEM -01SEASEs HYGIENE ..CONTROL MARKING--NO RESTRICTIONS DOCUMENT CLASS--UNCLASSIFIED ~~--PROXY REELIFRAME--3008/0730 STEP NIO--(IR/OZ48/TO/025/006/0050/0062 .jRr-_ArC_E-SS'ON NG--AP0137802-- NMI: 2/4 025 UNCLASSIFIED PROCESSING DATE--27NOV70 CIRC ACCESSION NO--AP0137802 ABSTRAC-I/EXTR4CT--(U) GP-0- ABSTRACT. THE PROSP.EiTivE PLAN FOR DEVELOPIMENT OF ;4EDICAL SCIENCE IN lq7t THROUGH 1~9 175 S! I'DULD DETERMINE THE GENERAL DIRECTIONS OF DEVELOPMENT OF MEDICINE IN OUR COUNTRY. AND IT IS ENT. OF ME()[ COB [OLOGI CAL DISCIPLINES TO EXTREMELY IMPORTANT FOR DEVELOPMC HELP SOLVE MEDICAL PROBLEMS OF.MAJOR SCIENTIFIC AND PRACTICAL IMPORTANCE. IN THE NEXT FIVE YEA-RS PRAC *TICAL HEDfCINE MUST BE EINRICHED WITH THE NEWEST METHODS AND MEANS OF rROPHYLAXISv~~DIAGNOSIS AND ~TREATMENT. OF PARTICULAR IMPORTANCE ARE :METHODOLOGICAL INVESTIGATIONS. 'PHILOSOPHICAL ISSUES IN MEDICINE AN0.PRO,8LEMS IN:~GENER,!kL PATHOLOGY MUST BE DEVEL'OPED EXTENSIVELY AND SERIOUSLY0 ~:THE GUIDING DOCUMENTS FOR 'PREPARING THE DRAFT PLAN OF DEVELOPMErIT OF MEDICAL SCLENCE IN L971-195 WERE THE DECREE Of THE CENTRAL COMMITT,E.E OF THE CPSU ANO USSR COUNCIL OF MINISTERS DATED 5 JULY 196,3v NO 517, "ON MEASURES-4-orz FUPTHER JMPROVEMENt OF PUBLIC HEALTHY AND oevELOPMENT, OF 41EDICIL SCIENCL IN THE NATION:, AND NO -760 DATED 24 SEPTEMBER 19W!' "ON'~iEASUil'ES TO INCREASE THE WORK OF SCIE14TIFIC ORGANIZATioNs A .ND 10 EXPEDITTE TiiE: USE IN THE NATIONAL ECONOMY OF. THE ADVANCtS -OF SCUENC. E A.140 7ECHNOLOGY". THE FIVE :YEAR PLAN OF SCIENTIFIC RESEARCH'FOR 197i-1975 INCLUDES MEDICAL PROBLEMS 'AN(;F 'RED BY THE,.PRESIDEL~lk OF, THE USSR AMS AND 'OF UNION SIGNIFIC ADMINISTC .5r-IENTIFfC MEDICAL COUNCIL OF THE USSR~ MINISTRY .(",Fl HEAj.TH. EACH PLAN FOR SrfENTIF[C RESEARCH 15 PRECEIvEa By~ !mWEXPILA~'ArlaRY INGTE WHICH. REPORTS ON THE CURRENT STATUS OF A GIVEN PR(JBLEM-.IN TIIE USSR AND IN WORLO -~SCIENCE. SUBSTANTIATION IS GIVEN FOR THE~~PURPOSEF IULNESS OF THE . PROPOSEO ..DIRECTIONS OF RESEARCH FOR THE~PERIOD IN.dUESTION,.- DATE-27NO1170 314 025 UNCLASSIFIE0 NWCEI S I NU CIRK ACCESSION NO--AP0137802 -ABSTRACTtEXTRACT-FOR ;:ACH ~)F THE MAIN 01RECTIC NS THE MhILIN SECTIONS (IF Ri::SEARCH APE GIVEN INDICATING DUE DATES AND THE M I N EXECUTIVE :rHE CENTRAL COK,14IrTEE INSTITUTIONS. . IN ACCOPOANCE W I TH THE. DECREE OF OF.THE CPSU AND USSR COUNCIL OF MINISTERS# 114 THIE: F IV YEAR PLAN SPEC.,AL -ATTENTION IS GIVEN TO VIR9LLlGYv, MALIGNA~T: NEGPLASIkSt CARDIOVASCULAR DISEASES, AND HYGJEINE. SCIEUTIFIC COUNCILS, PROLILEM~CDMMISSIONS OF THE USSR. AqS AND OF THE SC 1 ENT I F IC MEDI CAL'COUNC IL Ofd THE USSR MI N I STRY OF ..,HEALTH,,. THE HEAD UNSTITUTES AND DEPARTMENT OFFICES:: OF THE USSR! AIMS TOOK ACTIVE PART IN THE WORK PERTAI 114: ING, TO: LONG RANGE! :FORECASTING. A GENERAL ACADEMIC COUNCIL FOP, LONG RANGE FORECASTING, 'THE: AEMBERS OF WHICH INCLUDE THE GREATEST MEDICAL SCIENTISTS OF THE NATJ:t0Nv RAS CREATED UINOER THE PRESIDIUM OF THE USSR AMS TO DISCUSS FORECASTS OFAIAR TICULAR -IMPORTANCE TO THE DEVELOPMENT OF MEDICAL;!S~CICNCE..; FORECASrS PERTAINING T 0 CLIN.ICAL, EPIDEMIOLOGICAL, ANDaHYGIENIC,,ISSUES:WERE IDSUCSSED AND ARE STILL UNDER DISCUSSION BY THE PRESIDIUM OF: THE SCi-ENTIFIC: MEDICAL -~COUNCIL OF THE USSR MINISTRY OF- HEALTWOWTHE BASTS OF 'rHE REVIEWS OF COMPETENT COMMISSIONj' A 5 A RESULT OF:THE'WORK Dr.HNE, FORECASTS:IWERE 1) -RFSDICTION COMPILED ON MEDICAL ISSUES OF NATIONAL IMPORTANCEI;UN ER THE JU ")ICAL COUNCIL OF THE THE PRESIDIUM OF THE USSR At-AS ANDSCIENTIFIC 'USSR MINISTRY OF HEALTH. WITH REFERENCEITO TEACjj:PROBLEMt A FORECAST WAS MADE OF DEV,ELOPMENT OF THE DIRECTIONS THAT. Aft,ri: OF :THE GREATEST -RTANCE TO SOVIET PUBLIC HEALTH. -IMPO Uxle, L ASS F-F-I-ED-- 4/4 025 UNCL ASS I r- I ED PROCESSING OATE--27NOV70, CIRC ACCESSION NO-AP0137802 ABSTRACT/EXTRAICT-SPECIAL ATTENTION WAS DE~OTEO TO ~GEVELOPHENT OF COMPREHENSIVE THEORETMAL MEDIC0810LOGICAL RESEWH, GOCIOHYGIENIC -ASPECTS OF PROPHYLAXIS AND REHABILITATIO.Pit THE $E-,(IRCFI: AND ADOPTION OF NEW METHODS AND MEANS OF PROPHYLA'Al Sj~ DIAGNOSIS 41,140 MEATMENT. LIFE WILL MAKE CORRECTIONS IN THESE FOPECASTS, NEW 0fSC0Vr,-Kl'E5 IN SOME BRANCH OF MEDICINE MA~ ALTER THE MAIN UIPECTrON, HOWEVERt' WHEN PLANNING MEDICAL SCIEME GN THE 'NATION IT 'AL LEVEL, -IS IMPORTANT.td HAVE SOME IGENERAL UNES, A COMPLEX PLAN FOR THE HEDICAL PROBLEMS IN MW TliE ROLE.--PLAYEO B:Y DIlFFEiREllT-.MiST-l TI 'NS il!S~ 08~ tu b LNED. CLAS-STFIS 4a-ter Treatment UDC 542-48-004 USSR ~ZHDANOV, G. 5 "An Att Electrodialysis Desalination' Equipmelit" empt to Use Moscow, Vodosnabzhen:Lye i Sanitarnaya Tekhnika, No 6, 1971, pp 22-25 Abstract: Two cases are discussed of the application of electrodialysis equipment for desalination of water. Such equipment is. usee-at the Kazikh railroad system. The apparatus consists:of two blocks of electrodialyzers, a hydraulic block, control. ptuiel and protective covar for electrodialyzers. The dialyzer blocler-s consist of 300 alternating cationi(~.' and Vnionic mem- branes separated by I mm polyethylene sheets'.1 Each polyethylene sheet has a labyrinth type cutout for the passage of water., During operation of such equip---nt the diallyzers become clogged and have to be:periodically disas- sembled and treated with acid to remove the'sediment. Some equipment re- qtdre-s- this operation to be carried out Pvery,50-0 hrt. On others -- acid 5 vash,..Comblined trith water rinsers I's built:into the system, lowering dras- tically the need for disassetqbly of the electrodialyzers. /2 0.25 IJINCLASSIF tdD 1) It 0 C. E SSUNG DATE--230CT70 :t'1TLE--HI.GH TEMPERATURE X RAY STUDY 0.FT.HE.PEROVSKI ITEMODIFICATION OF tD_Tt0 SUB3 _U_ .w.'AUTHO"(03).-LEGEOEV, V.M,, VENEVTSEYI ;YUKON.: Z .,S NTRY 0 P. INFO_-USSR RCE--KRISTALLOGRAF IYA 19709 1512),. .37.7-91 'U:DATE PUBLISHED ------- 70 .'..SUBJECT AREAS--EARTH SCIENCES AND O'CEANOGRAPHY,:PHYSICS TAGS-;--CADMIU14 COMPOUND, TITANA. ERAL, CURIE POINT,, C TE, X RAY STUDY,: MINC '~--__NIOSIUM OXIDE, HIGH TEMPERATURE,EFFECT', ANTIFERROELECTRICITY _71'CONTROL MARKING--NO RESTRICTIONS ---DOCUMENT CLASS--UPICI-ASSIFIED ~-PROXY REELIFRAME--1997/0319 STEP NO--UR/0070/70/015/002/0377/0379 ,CIRC ACCESSION NO--AP0119306 _~j c-C-6-s-fic-f- L Lf .1 .11 it ;.A W It. I.! a 2/12 025 UNCLASSIFIED PROCESSING DATE--23JCT70 ~~CIRC ACCESSION NO--AP0119306 .'-.A6S.tRA(;T/ -XTRACT--IU) GP-0- A3STRACT. HIGH TEMP. (EDUAL TO -E A 120 0 DEGR E ES )X RAY DIFFRACTION STUDY OF. THE PHASE TRAINSIFION IN THE PEROVSKITE MODIFICATION OF CDTIO SUB3 WAS HADE TO CLA~IFY THE CONFLICTING LITERATURE DATA ON THE CURIE TEMP. Ao".1t) THE TRANSITION FROm ._'.THF FERROELEC-. TO THE ANTI FEIRROELEC. :STATE. THE Ti:S'f SPECIMENS WERE PREPD. BY THE USUAL CERAMIC PROCEDURE BY~FIRING.TWICE (AT 1050DEGREES AND IZ50DEGREES) A STOICHIOMETRtC RIXT..OF PURE CDCO SUB3 AND TIO SUB2 IN, A COO ATM, TO PRFVENT DECOMPN. OF THE CDTIO SUB3 FORMED. WITHIINI THE -TEIMP. RANGE. STUDIED, THE SUBLATTICE OF COTIG, SUb-31 SUSTAINED MONOCLINIC -_-DISTORTION. -AT ROOM TEMP.j THE LATTICE P'ARAMETERS COINCIDE WITH -:. - LS Ci B, AND V LITERATURE DATA, WITH INCREASING TEMP.i;PARAMETbRS A~E(IUA _..:-:PRIME0NE'rHIRD TEND TO INCREASE AND PARAMETERS 13-TA ANO 6-A DECREASE. THE RESULTS CONFIRMEO AN EARLIER CONCLUSIO,"i *rHAT COTIO SUB3 HAS A CURIE TGMP. OF EQUIVALENT 960DEGREES AND THAT BELOW THLS TEMP~ THE CQMPD~ IS --ANT I FEKROEL EC. THE CHARACTER OF THE TRANS(T'101N, A.T TH;_.* CURIE POINT IS SIMILAR TO THAT EARLIER REPORTE.D' FOR NANIIU.SUB3. FACILIrY: ~_NAUCH. ISSLED. Fflo KHIM. INST..*. 114.~ KARPOVA, MOSCOW, USSR. ,.7 UNCLASSIFIlED USSR UDIC 537-533-35/536.45 TITSNER, V. N. MIANOV, Gl. S., and VE. PHIgh-Temperature Electron Microscopy", ?bscow, Izvestiya Akademii Nauk SSSR, Seriya Fizicheskaya, Vol 36, No 6, pp 1266-1271 Abstraett The article shows that high-terripeerature stvdies can be performed in an electron microscope by using ibis electron.:beam of the microscope to heat objects. The specimen support is an apertured d1sk Tia'ade of tungsten foil, mounted in a socket covered with aheat-insulat~ng layer of aluninuirr, oxide. The heating of the disk is accomplished by a defocused electron be-an, a slight portion of which passes through a hole in the disk and creates an image of the object. The temperature. is measured by-mmans of' an optical pyrometer, focused on a mirror replacing the-interve(liate svreen of the microscope. The principal difficulty in measuring tem-ocratures above 10000 C is that the temperatirce is iiot the same for various sections of the disk due -to nonuniformity of -the current density.; -At.terlperatw~e.* ran;ring from room., temperature to. 20000 C the temiDerature measurement orror dofvi not cyceed sey- aral dozen dq;racs ~ The iraximum heating. tomporature- dopando on the proper- ties of the disk naterial and object and can 'exceed 30000 C. 68 USSR uDa 62i.7qi.763,i.oi1 KOIHZHO V. N., MEDKOt B. V., and ZfRaj Kiev F.olytechnic, Institute nThe, Detervdnation of the Magnitudc of thb Zone of.Plastic Deformations in Spot Welding of Thin-Sheet Constructioau"i Xiev, Avtomaticheskaya Svarka, No 1, Jaa ?2, pp 14-16 Abstract2 The effect of the dimensions of welded membim of low-carbon steel on the magnitude of the zone of a residual plastic defox=tions was investi- gated and a saimplified m-athod for its calculation is suggested. The me-thod -takes Into account the diztrlbutlons; of tho'iemparaturt", fron spot beating and of the maximum tenperature onithe edge of the vel&.vb1o henber, which depends on the section of the memb-er. The Xesults are:discussed on the basis of graphs showing the distribution of raximum tonperatures on specimen:, spot welded in their centers under different-,conditiow, and the calculated and ex rimental values of the radius of..,the~zone of mosidual plastic defor- pe nations. Their comparison shows 4 satisfactory consistency' tho average P -relative magnitude of the error being,iii, the':.:1im1ts of Thnte Mustrationsi seven bibliographiC Mftreince[34 ALIAL A4'~'j I- I'C") i'j U U A !JE T It I CAL -iTL= -METHOD OF D G T E RIM IN I N GR ESI DUA ST*kE SSE S I N :E AXI-AL'Y SYM.. ,HEATING OF TH I N PLATES -U- AUTH0R-(03)-ZHDAN3Vv I M., KORZHY 'I.N*t WSILENKO, VU~A. ::._.C_0UNTRY 'OF -INFO ~USSR S.OURr.E--ZAV00. LAB., 19701 36y, (2)r~ 2,13 .215 ATE PUBL I SHED-- ;,SUBJECT AqEAS--PHYSICS, MECH., IND&, CIVIL., BAND MWINE ENGP S S' A -JOH" TAGS--THERMAL MESS, STRE NALYS I S FLAT PALTEr METAL HEtMINGY GAGE MARKING-NO RESTRICTIONS 0 G C U'll EN TCL A S S--UNC LA 5 S I F I ED 'L.~w_~'-PROXY REELIPRAME-3003/0307 STEP NO--UR /00 3 2 t11 0 03 6 002 02 13 02 L 5 C TRC ACCESSION "40--APOL29539 UNCLASSIFIED --27PIOV70 028, UNCLAS,5 PRMES$ING WE .CIRC ACCESSION NO--AP0129539 ABSTRACT/EXTRACT-W) GP-0- AB.lA%TRACT A METHOD OF STUDYING THE RESIDUAL STReSSES IN THIN METAL PLATES AND WELDS: ARISING FROM THE AXIALLY _SYMMETRICAL HEATIN6 OF THF LATTER IS DESCRIBED, THE METHOD IS BASEL) ON THE. USE OF A SPECIAL, A~NNULAR REESISTANCE WIRE WHICH RESPONOS DIRECTLY TO THE STRESSES IN THE IMATERIAL. . THE PROC DURE-T E. O.dE ADOPTED IN 0. RESIDUAL STRESSES AT POINTS -CALIBRATI-NG THIS'DEVICE IS INDICATE A41S MAY BE OETEW[NED ~DEVIATI;JG: BY VAR ibus DISTANCES' FROM JHE H~EFATING, ~.BY ORILLING SMALL HOLES AT THE CORRESPONDING LOCATIONS'. UNCLASS !F [ED r 004260 Ace. Nr. M-1 Ref Code: _JL&e!~O 0 TPIZ S S-a ;L .4 r UDC 621.39 USSR 1. M FODVIDZI~~M.H. and AVAKOV, R A., ZHDANOV,- SHILOV, 0. S. flFrinciPles of Telephony and Theory ofITelephone Traffic. Text- book-for.Electrical Engineering Institutes of Communications" Osnovy telefonii i teorii telefonnykh soobshchetliy. Uchebnik d1va elektrotekhn. in-tov svyaz3-.:, (6f ish above),, Moscow, 'Svyaz." .19.69 304 Ps M. 84 k. (from RZh--~Elektrosvyaz No.11, Jan 70, Abstract No 1.64.64K) Translation: The principles of telephone transmission are consi- dered including telephone apparatus and its elements, switching (electromagnetic, relay,_electromechanical selectors, SrAmtdh* g leattents), procedures crossbar connectors and noncontact in e for an appraisal of the quaLity of telephone tvansmission, and calculation of telephone load and losses of me$~sageti. The prin- telephone switching are given-including the basit struc- ture and group formation ofautomatic telephone stations of cross- -Reel/Frame MTN USSR UDC 621.591.8 SMIRNOV, N.I., ZHDANOV, I.YU. Ouse Of Discrete Technology Elements During Reception.Of Cmaternary Signals" Moscow, Elelttrosyya2~1, No 12, Dee 31, p 62-48 Abstract; In order to confirm the possibility of creqtin6 a canonical circuit of a discrete matched filter of E-secuencee, -a mock-up-was assembled using the sequence duration n.r. 8. As elements of. the circuit., ~,ylurvi microcircuits of Typas 2MC41 and were used. A photograph is prevented of -16he upper and lower suboaquences Ej at the inaut of the discrete matched filter and en oscillograph of the aperiodic, fuhctiono-of autocbrrelqtion of this E-sequence. Various studies were conducted on the mock-up during ejhanEo of the subpulsee T in the range from 2 to 200 microsecond, when T = n T = 8 . 200o 10-6 12 millisecond. Analysis of the experimentally obtained aepl'oriodic functions of autocorrelation o' I various E-sequences showed that~in tho ouggested canon- ical circuit of a discrete matched filter, the level.6 :t the7lataral pins (vybros) of the function of autocorrelation will:not~excead Bevieral percent which completely agrees with theoretical cons Wers tions, . Reclaived by editors 25 Fab 71. 4 raf. fig. 5 tab. 41' - USSR UDC 621.385.6 STAROSTEMO, V.Y4 Uftndy Of Dispersion And The Amplitude Spectrum Of Space Harn-onice Cf A Hatere- Resonator Oomb Delay System" Radiatekhnika. Reep. mezhved. temat. nauch.-tekhn.ab (Radio Engineering. ~Republic Interdepartmental Thematic bcieh,tific-Technic~al Collection), 1971, Issue 17~ pp, 22-27 (from M-91ektronike. i:yeye 2rimbneLdje, No 3, March 1972, Abstract No WO) Translation: The problem of propagation. of elect roms IL-net ic ifavas in a hetero- resonator infinito:,y wide comb is solved bythe electrodynarnic method. Tile effect is studied of the geometrical parametleruon tho diepersion and the ampli- tude opectrum of space harmonica. It is shmin thatitho greatest effect on the characteriatic o:O the comb.provee to be the ~psrumatari) of tho hetero-rononance- noes the choice of which is very importunt:during conetruotion of' microwave electron devices. Summary. Vi 212 013 TJ?4'-L'A:SS t V It D DATE--- I! SF0'-,,j :V.1RC_ ACCESSIA114 `40--AP3100209 ..ABSTRAr_T/FXTR_ACT--(U) %;F1-0- ABSTRACT. R E AC T I ON 0 FI EOUALS CH SUL12) 'i CCL SU34 1.41TH SR IWITH DRY fC .4 N ~E` COOLM-1GAVE 99PERMT REO 2,2r6t6v TETqA4ETKYL,,Av 9XOPIPE.R-JPIN;_: TRM (7- S;~UILS Cf-OM GAVE 2r2.6, 6, T.crrR.I,V)4r--T~fYLt.4itiVDRO,X-~v,,, I '01X,nP1 PER MINE TP16POKIDE, I88--'0EGRE_:ES; 1 (1 EQUALS EMR1 GAVE DECOM110. 1. tZ EQUALS CHOSM. GAVE. 2.2-i-6 j,6#TET1W*ETHrLi 4 9 RD4 PI) 04,-70EGREES; I H _qXY,jj'0)(0PIPER [DINE TRIF14 , IDF9 DECOM .EQUAI _0j::-WVE 2,2 -6sTETRAMS YL,G4 -To OJOXr~P[Pfft]DIME TRE5ROMiOE, VIUDLFt,~DSCCOAD 67-29EGPEFES. REiCTION 0' %~- N F 11; W T TH , RR 0AVE -:61,-st4:i-.~(2t2s6-?t6tT-r-TPAMETHYLtl,OXOI~'IPERI:01,%E TRrBADMIDE11 PHTHALATEr 43-50EGiREES. UV SPEC TRAt:. CURMES: OF TYPICAL PitoDucrS ARE SHOWN. -T"JS I AND tf AR`E OXIDIZED BY-~ SR PRODUCTS #ITH -3 SR" ATIOMSZ. 1HE ABOVE STRUCTURES. IWER,;~- CONF IRIAE9 Olt NMQ ANC 1q, UNCLIASSIFtED ONICUAS~i'FTta PRO'ESSVING DATE-11SEPTO ~--JTLE-INTERACTION OF IMINOXYL RADICALS-WITH,CHLORINE -U-' -AUTHOR-* GOLUBEV, V.A., ZHDANOV, R.I.t ROZANTSEVt E.G. -C OUN TRY 00 INFO--USSR ~:MRC E- I ZV. AKALD. NAUK SSSR, SER. KHfM, 1970, (1), 184-5, 04TE~ ~PUBLISHFD ------- 70 ,-.-SUBJECT AREAS-CHEMISTRY, ORDNANCE TAGS--IMINE, CHLORINE, HETFROCYCLIC. NITROGEN COMPOWND, -~!crPYLF": DECOMPOSITION, FXPL0STVFt',POLYNUCL:t-AA HY0R0CAJRW,,4, ORPOUND X CWT C L"Ak:zKlVG--N0 ~,FSTRJ(JrOl,'45 ~.:'-'DCCUMENT CLASS--UNCLASSIFIEt) PROXY REEL/ FIRA14E-- 198 4/2665 STEP CIAC A C S S f MN M0-00,,'00269 17-11-IMIZZZ U,%, C. L A.S S I F I E- D 1-1---i6l-716~-7---'..., ; - ' i ;I - Lvic-t-Ilass-I "WA W, ; J- , :-" irl., 111; 1., - I I I., ~, . I . ~. - ... . . . . . 012 UNCLASS[f:~IED POCESSING 0ATE-18SEP70 .,TETLE--APPARATUS FOR SUPERIMPOSING TRIANGULAR VOLTAG;E PULSES ON A DROPPING ;MERCURY ELECTRODE AT A GIVEN MOMENT Or- DROP LIFE B.I..t KHOPINI A,Msj~ KNOTSt L,L .j..SA :OUNTRY, OF INFO--USS SOURCE-ELEKTROKHIMIYA 1970, 6(l),- 29.-34 DATE PURL-ISHED ------- 70 -:SUBJECT AREAS--CHEMISTRY ~..TOPK TAGS--DROPPING MERCURYv THALLIUM11* CADMIUMv I ul, ELECTROLYr[C --;.-'~REDUCTJON, BENZALOEHYDE, POLAROGRAPHIC ANALYZeA ,:.:"C'ONTROL MARKING--NO RESTRICTIONS CLASS--UNCLASSIFIED :.~.PROXY REEL/FRAME--1984/1815 STEP NO--IJP/0364/70/006/001/0029/0034 CIRC ACCESSION NO--APOL00389 UINCLASSIFIE0 2/2 012 UNCLASSIFIM PROCESSING DATE--18SEP70 C I RC ACCESSION NO-AP01003,99 ~~.~-ABSTRACT/EXTRACT--(U) GP-0- ABSTRACT. ~ME APP.t BASED ON THE SOLN. CONTG. TL PRIME POSITINIG POIENTIOSTAT, WAS TESTED BY USING A STDO A -THE STUDY OF A NO. THE AND CD PRIME2 POSITIVE AND FOR OF COMPDS. R E DIN. OF BENIALDEHYOE ON THE DROPPING MERCURY~ELECTRODES WAS STUDIED 1M A N' HCLO'SUB4 ALC. SOLN. THE ABSENCE OF ANODE- PEAKS;CORKESPONOING TO OXION. -_-.~~OF THE RADICALS TO THE INITIAL SUBSTANCE, ON THE~('YCLIC POLAROGRAMS IS ATTRIBUTED TO THE STAGE SUBSEQUENT.TO'THE ELECTRODE PROCESS PROCEEDING VERY RAPIDLY AND THE OXIDNo CURRENT OF THE INTE-RAEDIATE PRODUCT NOT -:,.REGISTERING PRIOR TO RATES OF.APPLICATION OF-THE.!POTENTIAL IN THE ORDER OF 100, -V-SE(; UNCLASSIFIED USSR UDC: 539.202 ZHDANOV,___V...__A., KOTTUSOV, V. F., and ZHUKOV, A. V., Institute of Mathematics and M1echanjcs,,Tom_sk State'University ".Computing the Mechanical Stability.of Iron, Molybdenum, and Tungsten Crystal Lattices" Tomsk, Izvestiya VUZ Fizika, No 10, 1972, pp 74-78 Abstract-: This paper is one of a series dealing with a method of investigating the behavior of,crystal lattices.:under conditions of arbitrary system voltage, all of which have appeared. in the journal named above. The preceding articles of-the series are briefly re- viewed, and their general purport is summed up in 1-1he statement that tangential stresses in which the orthorhombic iiyrametry of tlie lattice is preserved are most dangerous~for the lattice stability. U The tensor equations of state are derived for.the class of body- centered cubic lattices, to which ironi.molybdenum, and tungsten belong. A table-is given of the lattice mrametera, involved in these equations, for the three metals,~and.a second table provides critical stability values for~these,three metals for the case of shifts preserving the teu tragonal symmetry of -lie crystal lattice. Results of the analysis are also given in the form of curves. Zhdanoy. V. A., and V. F. Fenusov. 63 On t ,, th"ry of air equatinn of stale for nniidw, JjN- lIagl*ii9I,!,3-aniy po fizike. -1917-1967. Tomsk. Torrikiir universitet. 1971, B7-102. (ItZhKh, 11317Z, no, 1011:577) Consideration is given to 'he general propertita of equations of ottae derived in terms of q"~si-harmonic approximations of crystal lattices under the effect of mecha~nical stresses of an arbitrary type. The influence of tattice oymmetry on the form of the equations of.stata is clarified, aff well as that of the binding forces. A study in made of the critical states of crystal lattices prior to -..mechanical failure. Results of rusearch an a series of specific crystals are discussed. Malyshev, V. V. Equation of state for uraniarn hexalluoride over a wide rance of state paraniet"ra. Atomnaya enerSI7=.. 32. me- 4. 197z. 313. Experimental data on sat"rat 4-d vapor. pressure Ps, denbitiss P and A of UF vapor and Liquid at equHibr- v are approximated by the equations USSR UDC 539.1-01 V. -A. ZMANOV A. V. ZHUMI, luid A. V..POPO'V (Scient-Ific Research institute Of and Tomsk University) "The Effect of the First Qiantum- Correction an the CIviracteristics of Metallic Sodiun (Brief Cormunication)" Tomsk, 1zvesti,,,a VIA- Fizika (News of the Higher Educa~Uonal Institutions, Physics), fio. 9(-112), 1971, pp 126-128 Abstract - -Lrne principal char-acteri sties of,metal lic. s9dium are dete-n-iined on an M-20 dirital com~puter, uuing' t~-,- nonpara7D~tric fun6ticn of the binding enerTj and taking the first quantxul) correction into account. The results of the calcidations aTa conq)ar~d with ex-perirzental dixta alld the VJqon,,-ts-Fennj.-Dirvc ~A (TFD) moidel. Agreemient vith tjjc Oxperipialita-1 rioLta i&; Isnast exact for the finding epax-L~y, -Lho lattice constant in about 3-01) below the -,xperimental valiiep and the viodulus of elasticity is aboutu 20% above. AEraamant. wlth the UN'D Model is not as gacd but i.--praves vtfen the on.'ection i!-r applied. inamr7o.'Cent Of" the statistical approxination can be obtain,;,,d by higher-order quentiun corrections or 'by refining the iiod'el of t1he Tpetn-l- Orig. art. bas 1 table and 5 refs. LISSR ZHDANOVf V., Acadeniciant USSR Academy cf Medical Soiences.aad DireCtort '-Mamu"I'MO I v ic 01 Virology imeni D., I. Ivano skiyt USSR Academy of Medical 'Sciences "Uncovering the Secrets of Viruses" Moscow, VecheMaya Moskva, 10 NaY 71s, p.2 Abstracti This brief article relates the enthusiasm and diligence of Soviet wdical scientists in ca=ying out the,decisions.of.the 24th CPSU Congress, a.md-zentions i;ertain fields invfiid!i~;the Inititute o:VYirolbgy imeni D. I. Ivanovskiy is working, in both practical and:theoretical amas. They have been studying viimses which infect re-ople a~d anUala1n regions of the USSR zwt previously Investigated, and have already discovered foar unspecified previously unknown viruses. They comple-ted, a projectlon piepa~ng produc- t1on series of diagnostic medicines for practical use &.head,of schedule. A =zber of projects involving study of the molecular biology ~of the agents of infectious virus diseases in people and azim-als were paso completed ahead of schedule. A new discovery :Lnvolved learn'Ing-how virusis multiply in mito- abondrial that is, in the Intracellular orgmielles iihl.61h suplply the cell with energy, resources. In the clinical division ~pf-,thp 1;r,*I~ute the WSR's fl-Ist 24 USSR ZEWAROV, Academician, Academy of Medical. Sciences' USSR Wirology and Health" Moscow, Neditsinskaya Gazeta._20 Apr 71, p 3 Abstract: Researc~a 'by the author demonstrated that virus-speci-fic functionally active polyribasomes, which ensure synthesis. of viru;s-esnecific proteins, are :formed in the early stages of infectiontof cells of Ekich ascites carcionoma with Sendai parainfluenza virus. Further research le~; to the conclusion that primary genetic information in the -groups of viruses. studied vere carried ~.o the aites of protein synt-hesis by, ribonuclooprotains, aot by ribonaucloic acids. In a study of Venezuelan encaahal -,, i:t was learn:-:~d that 2-3 hours iti after infection of c:-dck fibroblasts, repli cation compluxes~of Lwo-strand riW=aleic acids were formed. In study-ing,,the prcduc~s of synthesis i-n sucrose and cesium chloride density gradients. r-ibollucleoDroteins were dAs- covered, one virus-speci-fic and tho others hybrids of infectious viral ribo- -nucleic acid and cell proteins. Prospects for the near,.future include syn- thesis of certain proteins in cell-frde syst6ms on a sOmi-industrial. scale. USSR 14ore Active Attack A(.,-a-,nst Influen za: Moscow Xedltsinskaya Gazata, 27 Jail 70, TP 1 Transle.-ion: At -- neetim of the Cqnittce~ fo the Conti*ol of .enzaa of the r 'Direc* or USSR Kinistry of Health, Professor 11. Zhdang D Of th:-! Inst e of Virology, UJSSR Acade:7~( 01 1~-'Z Ica, f b(.*Iences, delivered -.i report on the epidemio- lo-ical situation ---d forccastin~l at infilienza. Accordim.S to the data- of the AlIwUnlop- Dafluenza ccrtc-, there 11as been a recent rise in the in-cidenec of tois infe "~-Ihiie in Dem er of last year a rise ims nated in. -.ome c-Llu--Jieo, for -tion. Y2xosiavll a"N'L Ark-hangell.sk, at prer,=t -= increase Ln iniluenza '=.s been noted in Gth-er ',.reas. Influenza is cpused~mir-ly by type A '~io s ri:nus ard occurs chief Y in mde-.~It'e form. Mere are sow! caches of comp ca- zi due -to inlIaemia pneumonia, otitis, ard others)o AccordlrS to the dztta of -P-ro- fu'-zor Ye., I'L-ni3ladze. difforontial dlagrio!D3 uden, climilbal con~Utiomq s~401m~ that aLo-ac 3cre" of th-C influenza "'-'('.cti;rs 1-'11113fared I'Vom uxlj~llwwiruv in fection."'. Mis circumstance cam-not, be tUsi-egarded. . Not, ~alli- ~,rowxll are NID~r and promp tly coverea 4'i-Y y~=-ic inoculations. Occasionally pro-.21;ist ration of pc-itie--Its przoj~w is, no-ut un-111 orgp-~ized, a. sr=e polyclinics~ Occasional-J-X Pther diseases are dia,,-- nosed as influenza. we know. the chief source.,of*the'spreud of influt!nza infection Js a A z U 3R veditsinsl Gaze-ta, 27 Jan 70, 1 sick person. hloi-,ever, this is no t, realized by all, anti influenza S*GLI,7 on their feet",I thus infect-in,7 those around then,. T;h.:11-ra~Deu,G-ic alid- tie institutiono). trade itnions and other nalic Qrpnnizatti-*Mts r~lioald fl:,-hiv- allaijaut this most, vigo-rously. As de=nst--at-ed by at, inspection, ,:%;here i sni) tk, asufficientj s-upply of masks in Isome 'polyclinics, and =edicall. personnel do na-11 all~,rivs use t-hem,4 Professor P. Bur~7,--Sclr, deputy~ WSR' &Ui~sterz oL lleelth, spokee alt the session and set forth a nuffber of practical tasIks dealina can:trol of -.;atMu- enza for pifolic health end xedical- workers. 2/2 USSR UDC:629.78.002.i GERASIMENKO, G. I., AKSHENTSEVA, A. 1). , D. MAKAROVA, L S. I'Two-Layer Metal Type 3 Steel Plus N70NI27F fqr We I ded*' Appa -a us Used j n Ifighly Corrosivo Media" Sbs Nauch. Tr. Vses. N.-1. i Konstrukt. In-t KhIm. Nfashinostr. [Collected Scientific Works of All-Union Scientific Research andTosign Institute for Chemical Machine Building], 1973, No 6, pp 35-17 (Ty',1TISIated from Referativ- nyy Zhurnal..Ra~ctostroycniye, No 10, 1973, Astract No~ 10.41.156 from the resume) Translation: A technolovy is developed for welding and pressure working of a tvro-layer metal consisting of tyTe 3 steel plus NIVON127F, and areas of its application are defined.* An optimal ;heat-treatnient mode is recom- mended and it is shourn that beating to 700-8500 C for-2-5 hOtITS causes em- r and-reducesAts corrqs1on,resistance. brittlement of the c' dding laye 4 figures, 2 Tables., USSR f669.925:621.73ft620-171 MWKVIII9 N. I. j ZIMOOV, V. D., and SHWIAMV~.o G. N. ad :tor Aggressive "k Kew Flaterial for the Construction of S .eparators Design hedia!" Hoseowl KU-nichaskoye i Neftyanoye Mashinostroye'niye, Ko 2, Fab 73, pp 20-2.1 Abstracti Data are reported on the mechanical anVA 14echnologicia properties of large 1"orging pieces made from titanium alloy AT-6,; jrhioh,were to be used in the production of the components of sepurator drums. The-tuchnology of hot treatment (tempering) of large ingots frGm AT-6 titvviium alloy a5staes the requireed nochanical properties of the centrIfEr5al so-jan.tor components. Iii the xranga of tempering temperature --. 1150-850:C -- the Utcbnological characteristicz of the ingots were found. to bo adequatiii, Hawoverp to pro- paxe these coaponente: from titanium Ingot6 It was naceamaxy to drop forge was econ6aicaaly more advan eous. hi ~Vta iWtst w ch improved the reliability, and _36-, !~__T _!T_ 7-7-7- USSR UJP G621.382(047-1) MANOV V.I., AKSENOV, A.I., BORISOV, V.A4, MITROYANOV,''A.V. 'New Sem I.-conductor Devices For Radioelectronice Apparatus" K -lauch. Elektron. takhnila. 1, -tekhn. ob. Poluprovodn. priboxv (Electronics Tach- nology~ Scientific-Teebrical Collection. Semiconductor Dovices), 1970, lanue 2t5q), pp,11-20 (from Rth--Elektronijia i YeYe eneniyo, No 10, October 1971, Abstract No 1OB9) Tranalation; The paper conoidart; the principal-characteriatics and directicna in the development'of contemporary diucrete comiconduotor devicou for radio- electronics apparatus for wide-scale applicution. In the'dovelopment of Power trunaiatorat three principal diroctlons aro indicated- (1) Creation of a trans- istor for. increasing ~ho power with a high criticol f roq~i,_-ncy. or amplif ication. of the curront and amill intoreleatrodo c4pacituncou apPlicable to high-Prequancy ;e emcuM of and microwavo tachniquoe; (2) Davelopmentof a tranolni-xjr with, u larg I, production of the =axi-ra current of the callaotor at thc pertaic-niblo collector voltage with large power dissipation and a critical frequenry:or amplification up to 20 MHz) broadening use in amplifier vnd:9w#ch:ing ciricuitij; and (3) Creation of high-volta&e transistors necessary for:the final atav of the horizontal sweep of television and a number of other eirculte* 7 ill- Mi, 1-57 USSR me 6v. o3-4.44.- 612 8' 23 5.2 51 BO.-anzi--mv-, A. I.,--7HnZQL rALCMMjr A. G.,: YQ. -IN. X and SE[P-1-ISHMVAP A. M.$ MOSCOW c Rtesearclh institute of Bye Diseases iment, Belzholz- "Light-Induced Visual- Cortical Potentials in NWn" Moscov, Doklady Xmdezii N---,ik- SSSR, Vol 201,,N0 3 19713 PP T21 -r,- 3 P Abstract: In an investigation perform-ed on 4g healthy inan ard women, e-mlked motentlals vere recorded 1-~=i the vistial cortex.(ona eli.lctrade over the am." repreventing the macula lutea and the other electrode 3; cxi higher along the =dian line) vhile the subjects looked at intervdttent flasht-s of photopic and scotopic light. Averaged EEG records revealei the presence of evoked potentials in res-ponse to not on],y p-hotopic but also scatopic stimuli, although in the latter case the evokedipotentials vere less ntunerous and had a different pattern and a longer latent period. Simultaneous auditory stinra- lation (800 cyc/sec, 85 c1b) reducedthe amplittide of thd potentials evoked byscotopid stimuli but did not change the potentials evoked by photopic ztimLU. The exact imechanism of action and the signifitaace of the findings remain to be elucidated. Ili 0 Z 7 T'%-LA 3S,l F I PR9C-E'~~P4G DATE fl-;Z TKI INTR.ACRANIAL P;~.ESSVAE FLLICTUAT13NS :__.~,.ISEC tj.'t RY TU S cr- Tb4F_.,- OIIENC~PHALON Ut AsYlk., PANTlYFLEVA,~.V4.4'a-v ZMANK!Vt V6K. --USSR WNTAY OF I NFO NR* _F---vESTN:lK t3FTAL'.4,.)L'jGltv 19701 pp 55-58i JDATE PUt L ISHE D 0 APEAS-BIOLOGICAL AND MEDICAL SCIENCES PIC.TAGS--3RAINv INTRACRANIAL PRESSUREv Dl.AGN0STlC:MFDlCt-VEt ELECTRIC S C HARGE dlUk~LECTRIC PHENO',kiENON CON T R U Lt.*AP.KIKG--N() RESTRICTIONS C L A S S-UNCL A S S I F I E D RE~L/FRAME--198610H04 STFP NO--UR103ST/*TOIOO(,'1002/0055/0058 'c:C,lRC ~ACCESSKN 4NB--AP0102767 UNCLASS AIF IED ..'2/2 027 UNCLASSrFlEb PAOCESSING DATE--02JCT70 CARC ACCESSI-ON NO--AP0102767 Ali STP MCI T/ EXT RAC I-- I U) (;P-0- AB 5 T R ACTATOTAL OF 33C FLUTRIC STIMULI IN THe HYPOTHALAMUS, DIFFERENT AREAS OF THE BRAIN, BODY AND EXTREMITIES WERF 1,mPARTED TO 5 RA61TS IN 10 TESTS WITH THE mm OF ELUCIDATING 'lEZH1vM5M5 60VER'qING VARIATIONS IN THE LEVEL OF TIT-: N S I 'N' INTRADCJLA~ Tl_ FULLOV~l NG STIMULATION OF THE DEINCEPHALON1.141TH El-r.CTRIC ~Ljl;IENIT. IN S.TIMULATICIN A SERIES OF COMPLEMENTARY 0AYES, 'WHICH of--peo UP,;,,i CHAi.UJI C-103D SUP': AND T. E T'NE OF INMAOCULAR -ILY ii YFSSLSL, E%AER(;FD -IN THE 8AS[C WAVES OF THE OPTHALMUPHETHYSMOGRAM. . INVFSTIGATIONS SHavic-`) THAT CH.ANGES IN THE AMOUNT OF BLOOD FELLIN IG VITRAOCULAR. VESSESL 1.5 ONE JF THE ~PRIME..FACTOAS CAUSING FLUCTUATIONS OF:THE OPHTf4ALKITONE IN STtMULATIJN 'OF THE-DIENCEPHALO.N. AN II)ENT.ITY.DF~OPHTHALMOPLFTHYS-'4C)GRAPH[C CHANGES IN ELECTRIC STIMULATION OF TkE.H,YPOTHALMAUS AND OTHER PARTS OF MAL: BODY WAS ASCIEUXINED'o' HE A h I -LASSfFlE-D---- 4/2 008 ~PRCCESSING DATE--30OCT70 UNCLA '.JJTLE--RE-ACT.ION OF CHLOROMETHYLALKOMFLANES WITH. -,.....-N',PHENYLAMINOETHOXY.rALKYL,siLANES.. U-,. 'AUTHOR-(03)- PAKHOMWt V.1 ~ARKHIPOVv L.A- jH Arl, A.t -CIOUNTRY OF INFO--USSR -6 OURCE-I-IZV. AKAD. NAUK SSSR, SER. KHIM4: 1970f (2)v:39Z PUBLISHED------70 UBJECT AREAS--CHEMTSTRY :-JOPIC TA,GS--URGA4IC SILANE, CHLORMATED 6RGANIC C04POUNI), HETEROCYcLIC COMPOUNDt DISTILLATIONt AMINE, BENZENE DERIVATIVE, ALKOXIDE -~,TONTROL MARKING--NG RESTRICTIONS -.~:OOCUMENT CLASS--UNCLASSIFIED _k.0XY REEL/FRA, STEP NO--UR/0062/70/iDOO/002/0392/'0396 ME-1997/1765 CiRC ACCE.SSIGN NO--AP0120472 UNCLASS (IF LEO USSR IIDC 576.858-%ff .23 -BUKEOZIM U-, A. G., ZIMANOV, V. M. Subkletochnyye sistemy v virusologii (Subcellular Systems in Virology), Moscow, 'tsina, 1973 -int d Yedi 239 pp., 3,000 copies pi 14 Abstract The m -oted "'o one of: the nevest and most ur6ent probler-s noaraDh is deN of virology and nolecular biology: the use,of sut-celitilar systems in Virology. Subeellialar systeris have been used in.the cormerUtivelly recont rkist, partit!u- y after the discinrerj of the r-echanisms entatled':Ln the biasjmthesis of larl, the basic biological polymers: nucleic acids and proteins. Tie substantial amount ol raterial on -.be use of acelliLlar ~systems tImt has been arassed up to nov Im the study of viral blosymthesis is only partially presented in reviews published in various periodicals. The present book is one of the first attempts to olwmarize current infor- mation on this problem. In addition to data fror,, the literature, the monograph presents vast experimental material: obtained.by the authors. The book is intended for readers int~restedln virology, molecular biology, and the molecular basis of the pathogerie sis of infectious d1seases. Foreword In considerable measure the develp --4&. of virolo~gy has 'been determined p b the methodological potential for the study of vlrus!,and viral infections. USSR WIU~TMCAYA, A. G.j MANN, V. M., Subkletochnyye sisteiky v virusologii, Yleditsina, 1973, 239 PP Foll(rding the discovery of the first viral diseases of plez-Aul arit:L-As and hLmans the basic method of studying virru es was the reliroduction of vii-al infec- tions in natuxal 'los's and (for viruses afflicting, man.)~ laboi-atory animals. MAs method is still "imortant today for'the study of tbe development of infec- tion and immity in the case of viral diseases and foil the study oi- neoplastic processes caused by viruses. A particular place in virological research mathods has been taken up with the application of,chick embryos that,have proven to be sensitive to rn_T~ aninal virases and that have: been suitable for the accimulan- nt for ph, -ehemical study. tion of the virus in quantities sufficie Tsico In the early 1950's, a technique wns developad f or~ the groidng of singlo- laye.- cell cultures arki it has I-ecome broadiy kpplliud in. virolor-_ in a sho.- V space of t:Lme. The ap lication of the single-layer cell- cultures made i, Pos- sible to overcome the 'Nirrier of.insusceptibility of laboratory ani-mols to rar Imm species, and resulted in.the discovery of a num'I)er of new viruser. t1lat could not be isolated in laborato:rj animzls.~ Cell. cultures also proved to be suitable for the accur,10-attion of viruses,. for the study of the cycle of their reproduction and mrvhwSemmesisl -and In coi:fbination irith. radio-active 5-sotopes -- hemical st-,xkr of Tzrticulars of metabolic pacesses in for the bioc. the infected .2/7 81 USSR BIPMUSKAYA, A. G., MakNOV, V. in., Subkletochnyye sisteigy- v virusologii, Med-Itsina, 1973, 239 PP cell and in the synthesis of viral- and virus-specific prCalicts. '11he method of s~ffngie-layer cell cultures created the possibility for the elevalopment of research on the molecular bioloU., of virruses in animals. This research -~-ns develo-ced so-meVaat earlle., in the study of bacterial viruses (bacteriorhqKes) Uous was elab- since t:he technique o,' producimg cultures of bacterial populat orated already in the latter part of. the last century. At -the present time, the cox sponding cell cultures are also used for the investigation of viruses of plants,, and insects. -esee r of virases maturally 1he develoDrent of 1 rch on the molecular biolon created the necessity of developing methods for producinig, subcellullar structures and fractions for the study of individual stages of virus-induced synthesis nthesis of vii-al i)rotains and viral nucleic acids. iti 1. - the e the sy In a, V r, =etthcods were applied r the study of the reprodnetion of bacteriopha,,es and fo ani, 1s d ve,3etables. soon thereafter for the investigation of the viruses oT_ na an The use of subcellu~lar system zmde it possible. to obtain' important informatiou on many links of virus -induceed s~mthesis at the~:molecular. level and of late to reproduce the biosynthesis of viral nucleic acids and of ribonucleoDroteins possessing, infectious properties outside the cell. 3/7 USSR BUKRINSKAY-4. A. G., Subk'-'etoclinyye sistemY v vimsOlOgii, bludit -sina, 1973, 239 pp The authors were inspired to wite the book owing to the fact that the large amount of factual material that has been accumulated: up to now has only in nart been summarized in surveys and in individual chapters of monographs and multiple-volume works on virology and molecular biology. The authors have limited the monograph solely to work.s concerning the viruses of animals. 1~hterials referring to ibacterial vinises are cited only as exceptions. In the literature devoted to the problem under investigation systems of Vntheesis of biological macromolecules in subeellular stnictures and fractions of cells are also not inf requently desi&mated as subcellular, acellular or en systems. We decided to use the first of these designations since it most 0 P precisely reflects the substance of the systems in which istructiwes or frac- tions or derivatives of cells are al,4ays used in -one degree or another. Contents Pag ,e Foreword ...... ........... ........ ........ ........ ...... 3 Chapter I. Polymerase systens in MA-containing viruses .................. 5 1. RaDliCation of DNA-containing viruses ................................. 5 DIM-polymer ase systems .................................................. 9 /7 "7 USSR BJMI'KSKAYAY A. G., Subkletochnyye sisterky v vlrusologii.,. 14--ditsina, 1973, 2 39 I_Dp 3. D, -polymer-ases in DDIA-containing viruses of anJjrals ................. 4. DIM-dependent RIM-polymerases: in animal -tidsue ................. MIN-polynerases in DITA-containiqg animdl viruses ................. ~Awxiliarj en--7yn-- systems ......................... ................... Bibliography .................................. ......... ................. Chapter II. Polymerase systems in RDTA-containing viruses, . ................ 1. Reproduction of RITA-containir-G.virdses: ............................... 2. Production of poly~iierase complexes ............... ........... 3- Fo-rmtion of polymerase reactions ........................... 4. ......... 4. Kinetics of pol:jm--rase reactions* ................................. ... 5- Polymerase systems in various viruses...., ....... I .......... Bibliography ................... ........ .......... ............... Chapter HI. Structure and functioning of animal polysomes ............... 1. General schema of protein biosyifthesis ...................... I....... 1. .2. Physicochemicall properties of rilbosomes and polysomes ................. 3. Ribozucleicacids participating in translatiorms , ...... ....... Particulars in the structure, of the ribopoWs of aninmls ......... Functioning of the polysons of . . . . . . . .. . . . . .4. . . . . . . . 12 17 19 2 7 31 35 35 42 46 118 51 81 84 84 87 91 102 107 5/7 USSR BUKRIRSKAYA, A. G.,1 Subkletochny-ye sistemy v virusologii, Meditsina, 1973, '239 pp a ........................ 117 6. Protein-synthesizirk-, system of Wtochondr4 7. Pa-rticulars, in the regulation of translations ....................... 118 8. Inhibitors affecting translation ............... t ....... * 121 9. Translation in cells damaged by viruses .............................. 124 Bibl J ography ............................. ............... I .......... 132 Chapter IV. Acellular systems of animal o .rigin ....... . 138 .............. Introduction ....................... .......... 138 1. The functionina of an acellu-1arisystem. ......... ............... 139 2. The identification of proteins, aynthesized- in vivo and in vitro 3- Heterological acellular systems ................ 146 4. Determining the 'rate of tr nslation 5- Determinin-g.the number of active ribosomes and the namber of peeptidee bonds fomed by each ribosome.; ....... 148 ............ ...... 6. Rtbosomes in cell structures ..................... I .................. 150 7- Production of cellular mRNA ....... #...... .......................... 154 8. V4thods of producing and description.oZ*certain ace3aular systems of animal origin ............ 0 . . . . . . . . . . . . .. . . . . . . . . . .158 Bibliography .................... ........................................ 171 6/7 USSR ~BMINSKAYA, A. G. Subkletochnyye sistemy v virusologii, 'Meditsina, 1973., 239 pp Chapter V. Acelliil r systems in the study,of the translat-ion. of JUTA in animal viruses ........ ............... :................... 175 Introduction .................................. ................. ...... 175 1. Properties of viral- mRNA ......................... 0....... 175 2.. Bonding of viral RNA to ribosomes.., ......... .................. 183 3. Translation of viral RNA in~acellularsystems .... ....... 193 4. Nature of protein products synthesized in an acellular system in the translation of the RM.of animal vinises... ........... ...... 2021 Acellular systems in the study.of the actim of interferon ... 211 'Bibliography ........ ........ ......... ...... 219 ................... Chapter VI. FcAred synthetic systems .................................... 221 1. Bacterial systems ........... ............. I ............................ 221 2. Synthesis of -ribonucleoproteins of arbovirases ......... 4 ............ 223 Replication of viral RNA in ieolated~mitochondria .................. 231 Bibliography .............................. ....... .......... 237 7/7 Hicrolb Ogy~ USSR UDC 576.858.6.083.35.07 ZH-QANO-V, V. BYKOVSKIY, A. F., AL'TSHTEYN, A. D., LOZINSKIY, T. F., URYVAYEV, L. V., VOLKOVA, M. L., YERSHOV, F. I., IL'0, K. V., BEKTEIUROV, T. A., IRLIN, I. S., MILLER, G.-G., ZAKRAROVA, L. G.,;PEREKREST, V. V., GERASINA, S. F., and SEVAST'YANOVA, M. V., Institute9f Virology imeni D. 1. Ivanovskiy, Academy of Medical Sciences USSR, and the Institute of Epidemiology and Microbiology imeni N. F. GAmaleya, Moscow Detection of Oncornaviruses in Continuous Tissue Cult uTes Moscow, Voprosy Virusologii, No 4, 1973i p0 41l-414 Abstract: Studies were conducted on a number of human and animal continuous tissue cultures maintained in medium 199 containing 10% bovine serum to determine oncornaviruses. Formation of oncornaviruses in the tissue cultures were followed by the appearance ofvirtal particles in the culture fluid labeled with H3-uridine, susceptibility of their synthesis to low actino- mycin D concentrations, appearance of these particles following inhibition of nuclear material synthesis by bromodeoxyuridine or ulitomXcin, presence of reverse transcriptase in these p4trticloso preaieriu of 60-70 S HNA in thane particlea, and alectron vileroscopy. Of. the 26 hquin 1:1nes, 1&nves~fgatexl 14 contained type 8 oncorftavirus, and 4 lined type C vivts. 'Eight of the USSR UDC 578.6 -YERSHOV, F. I., BYKOVSKTY, A* F, SOKOLOVA, T. M.,:and V. M., Xi~,mber Academy.of Medi al~-S of c ciences USSR,.Institute 'Virology imeni D. I. IvancrFskiy Academy of Medical.'Scleaces USSR, Moscow "The Morphology of Hybrid Ribonucleoprotein Complexes (Pseudoviruses)" Moscow, Doklady Akademii Nauk SSSR, Vol 210, No, 5, 1973, pp 1206-1207 Abstract: It was established iii earlier work by Yervbov et al (DAN SSSR, Vol 189, No 4, 882, 1969) that addition of the infectious RNA of the virus -of Venezuelan equine encephalomyelitis to the fraction S 105 of the hyalo- plasm of chick embryo fibroblasts results in the formation of hybrid ribo- nucleoprotein (FIIP) complexes (pseudoviruses) that t6asist of the virus RNA t and call proteins and differ from the virian RNP in regard to their sedi- mentation distribution and floating-density. They are insensitive to the action of antivirus antibodies, but at the same time exhibit infectious activity., In the work reported at pres6nt,-.the morphology of the pseudo- viruses in question was studied by electron microscopy. It was established that the optimin, ratio for the.formation of the RINP coraplexes was 400 gamma. virus WNTA to 1.6 mg protein. On purification of the W complexes (pseudo- viruses) by centrifuging In a 10-30% density gradient.of sucrose dissolved 1/2, 4: USSR UDC 576-858-25-OB'3-35-095-383-098-39~-332 SAW= V. M. BOCIMMOLOVA IT. 11.) GAVRILOV, V-~ I., and NEFLATARIDZE, 0. G., Institute of Virology imeni D. I.Ivanovskiy, Acad,eny of Medical Sciences USSR, I nistr th:USSR, Moscow and Institute of Viral Preparations, 1,d r.of Pvblic B~alt. "Chronic Infection of Cell Cultures by Tick-Box;ne Encephalitis Virus: __'DesdriDtion of Ribonucleic Acid Moscowil Voprosy Virusologii, No 1, 1973) PP 23.27 Abstrant: Viral MNA produced in SPE X cells (acute infection) and Mp-2-Sof cells (latent infection) infected by tick-borne encephalitis virus was compared. dimuntation constants Viral RNA of both c,-Ature types was identical - Ath seL ranging from 16S to 26S 3. hawr after infection (Pmk at 20-225) and 45S 5 hournafter infection. The 16s-26s ival which vas partiv.11y :(~,Vr:.istant -to R',!.'A- ase,' in considered to be an internecliate form., iftile th 45S M1A ~,as incor porated into ribonucleoprotein structures, Twq)arison vith data on Vene~~uelan equine encephalitis virus showe& that: the stucUed virus is soT~12iiriat larcer -ons. with a molecular weight of about 3-2 million dalt LYSSR VW 576 -858 (roronavirus) .037 - 45 'AYA InDtitute of SBEBOLDOV, A. V.) ZAKSTELIR, L. Ya., and 7 Virology.imeni D. I. Ivanovskiy, Academy 0 . ~Mdoz Sciences USSR, I-Ioscow Sedimentation and Density Characteristics of Coronavirms" Y4 s c o w., Voprosy Virusologii, NO 1, 1973P PP 59-04 Abstract. A method for labeling cor-onavirus vith H3-uridine after its intra- cerebral inoculation into newborn mice followed by purification and concentra- tion of..~he virus has been developed. High-speed centrifugation of the result- ing preparations in a sucrose density gradient and equilEarimn centrifugation in a cesiiun chloride density gradient showed. virions of coyonaviras strain OC43 to have a sedimentation const-ant of 280S and a buoyant density of 1.24 gn/ml, vhile internal ribonucleopy7otein had a sedimentation constant of 180S and density 1-31 cpi/mi. Virion parm-neters are. more simllar. to those of arb-mrimses and'myxovirimez and less so to those of parcuny.-covi-ruses, i4hile ribonucleo-protein parameters resemble those of the 'latter. Detergent tr eatment of the prepara- tions causes them to lose hemagglutinating ability but infectivity WPIS main-1. ed, probably becaus-e- the. hema tainin7 lipid membrane is -air gglutinin-con 9 destroyed but ribomm-leoproteins, which,can stimulate i nf'~mtion, remain intact. to degener-ate -uctures are wiusuallyT raglle and. tew~ Virions.and subviral sti U~ spontaneously. 0, 'USSR uDc 616.9~8-25-092.4-o-:6i6-ooS-939.633.2-0-~2.18- 07 Mr DOGOMOWVA '11. N., ana MRILOV, V. I., FLM KO, 8.~ M.; ANDZWARIDZE, 0. G., Institute of Virology I m-ni D. 1. Tvanmrskiy, Academy of Medid6l-sciences USSR, and Institute of Viral Preparations, Mirdstvj of Public Health USSR, Mscow "Chronic' Infection of Cell Cultures by Tick-Borne Bneephalitis Virus: Ribonu- cleoprotein Structures in Cells" Moseov, Voprosy Virusologii, Vo 1, 1973, PP 1-7-23 Abstract: Labeled MIA Drecursors were added to Mip-2-Sof cell cultuTes chronicaUy infected vith tick-borne encephalitis virus;p in Ywhich cellular RNAI pr t synthesis was su -iressed antibiotically, to deteimitne the loca ion and nature -us -is - oun o once- rate of viral products. Vii -specific ribonucleoprote-in w f a t c ut in mitochondrial membrane fractions. Tim, fonns, v~ith 160S and 140S sedimenta- tion constants were detected by sucrose gradient analysis. Densities were 163 and 1v42 Gm/ml re6pectively in cesium~chloride gradients. Blectron mdcro- scope, imiestiption indicated that the structures were thread-- 2.4-2.9 microns long, and.50 X and 30-40 ~ wide respectively.', 7hreads of inte=ndiate sizes were also detected. Thene &ata suaaes' that ese are viral genomes. It is h 1/2 USSR u-Dc 6a,61988.25-OT-4-OB5-373-3 AZADOVA, N. B., _,?~1WA1TQV,,--V. M., KOPEL'MM, R. N.) and GAIMILOV.1 V. I., Institute of Virology imeni D I. Ivanovskiy,, Academy of Madical Sciences USSR, ~-bscow "Virologi-cal Characteristics of Infection in the L Cell-Sindbis Virus System in the.Presence of Antivii-al Serum" Mosciow) Voprosy Vi:mtsologii, 140 p/lOct 723 pp 520-523 5~ S6 Abstract: Persistent infection in the L-SV system (multiplicity of infection O.-Ol tTU/ctell) in the presence of 0.5% of.specific antivirus serum was charact- the erized by alternatir...- pimses of degeneration and proliferat4on durini, ,as, with. virus and. hermaj-%Litinin preilent in the cultlire red4-,xr;. fir-ut three pansar DurinG the rcimninder of the 90--day, long peri old. of ~ observation, proliferatior-, predoadnated, the he~~mgglutinin titer fell to a low level, and the virus waG frequently absent. This suggested~narked inhibition of viru,- synthesis. How- ever, immmunornorphological investigations revealed active synthesis of two structural proteins of Sindbis vi-rus -- ribonucleoprote-In and lip.0-protein r;iem- brane antigen -- in 70%o of the cells. It.is concluded that a r~--rsistent infec- n ru tion which causes cellular exhaustion does not arrest sy thes 8 of v pi,)- teins but only prevents the viruzes from q(,,(~,rogating, and-, leavi-n;.r, the co. .1 We infection iz trammitted from one pnsaaeu to anothell by daughter cells 1/2 -I- an rjivb-r"p -- -- - ,, ........ . .;.Iltr - TJBSR UDC: 576.858'?"t5-Oq5-383 AMMIGEL I SKIY) YE. V. CEMMIS, G. -K. S.., DERKAM, YU. S, X(M- V,_T - CL _,N 11~1. Institute of Virology imeni Di 1. Ivanovski:t., Academy of cal Sciences US SR, Moscow "New Evidence that Influenza Virus Can Be IFreed 46f East Cell Antigens" Mscovi. VoProsY Vinisologii, No 5, Sep/06t~ 72, pp 586-591 Abstract.- AO/PRB influenza virus aivrays contains host cell antigens. Species- specific chicken antigen is located on the surface of the ~vlrus;, while Forssman's heterogenous antigen and group specific A antigen are incorporated prepiieLfied through into deeper structures. By exposing _nflue4za virus cellulose ion-exchange colLurn chrorm-Atography- to. the en ymati~_ activity of J Ar7psini the antigens can be removed from-thelvirus,as-evidenced by - -ino- -116ds. Infiluenza virus chemical and fractional analysis and-by radioisotope met treated with trypsin pri!serves its bidlogical Dro However, it no pertiesi ~! 1onger exhibits its activity toward tissue ajiti6era and reacts only with virus- ific antisera. Spec 27 USS.R UDC 576. 8 0 -1 V ~W- VA 12 v.. T 8-30f,-332-C95.3,03 12, InHov V1 Z'01 . . a ncl I a T lJK,!,_. -1 van O-T~v Academy; V. A S4. udy nces UISSP Of the OMDlex of C -ing Bet Tweell Viral. R1,11A arg, Ce:Ll Pl*oteills" No 61 Abstr__ct c 72, m) 670-1 576 lai -tall PIC of E;-Ibry a 'fne enCe_.~h' and 7'C-liti 0`-e_:_ns_ cc,:,- not sedil- ~:e,3 i jull a il" -a D 4-ha 033 t 2 C 21 1171 C "gilt" On 11, -ted b)r q with. oil"". to t On r- th IQ a -L, the I vl~_, 11 rl llrotein a in 0 "Telwat natio 1, "CIL 4. C 3. n C arl t su j j.; hi ~)L%aj4C C)f "u _1 lonic causet; OX11' Co.*.'T~tjet IMWAUV) L. V., et al., Voprosy Virusologii, ITo 6, Nmir/A~C 72, pi) 670-676 -eaclily protein. Though the biologica silmifIcance of RNA: cannot react i I I - protein complexing rermains unclear, the Pact that such ~Cmm-:Loxes arlse in iso- toni,c redia sui'%'est that rmch structures exist in inrec~teu ceLls. The rela- tionship between the vicight increase of viraL.RNA and the ( tity f y t n 'ro ei available suggests that when protein is low in quantity, it distributes itself l Rr dinentatioi Yate does not increase unifonn]:j a~mn- aL Lh molecules, and RNA. se I noticeably. 2 /P- Immunallogy. USSR UDCi576.858.25.097.2 URYVAYEV, L. V., CHEPULIS, G.-K., DERKACH, Yu. S., ZIIM"V and YERSHOV,.F. I., Institute of Virology imeni D. I. Tvanovskiy, Academy of Medical Sciences USSR "Protein Components and Antigens of Venezuelan Equine Encephalomyelitis Virus" Moscow, Voprosy Virusologii, No 5, 1971, pp 586-589 Abstract: The protein composition of highly purified Venezuelan equine encephalomyelitis virus was studied by electrophoresis in polyacrylamide gel and by double diffusion in agar. Both methods reve~aled the presence in the virus particles of three virus-sp6cific proteins. with antigenic properties. USSR UDC 616.988.75-084.1,7 "1969"' BOBYLEVA, T. K. , SLEPUTS11KIN, A. N., RUSSINA, A. Ye., VITKT.NA, B. S., GRIINMERG, I. R., TAIVSOV, A. A., LIVERGAND, 11. 1,, and Zg"V M., Institute of Virology imcni Ivanovskiy, Academy of Science8:TJSSR, an Smolanskaya Oblast Sanitary Epidemiological Station "Evaluation of the Efficacy of Mass:Vaccinations Againsv Influenza" Report III ffik-!"obiolo-ii, Epidemiolo~ii i I c aj, Zhurnal I mmunobiologii No 9, 1971, pp 18-23 Abstract: Double vaccination of approximately 5 0 of the population of the city of Smolensk with live influenza vaccine.in. 1.968 proved to be effective In controllin- the disease even during the :1969 epidemic, caus,-:!d by a new antigenic variant of type A influenza virus. Almost half as -many contracted the disease as in the nearby cities of: Vitebsk and, Kaliip, where the population was not vaccinated -- 28. 81 54.3 -anc reispectivel~ The difference 48.7 between the adult sick rates was even gregiter 17.9, 138.1, .,trtd 41.2%, respectively. The side effects of the vacaine were minimal. : The rcsults of a similar nass vaccination oro-ram in Yartsevo were poor it I,ainl%, because vaccine from the spmc, strain had been used. for three succe.ssive:~years and most of the people had become immune to it. Hence tha va.ccinc~ strains should be. changed periodically (once every 2 or 3 years). USSR UDC 576.858 GAy-- , and, finallv, tissuo cultures (robbins a;~d Pndars) includitij,organ-oill c (SynPostum 'of Orgau.Cultur ~. tacli of elisc =thoda,. opecially the Lls;t ant, e~pandcis the opportunities for Is-,latteiii and inveutigaiiq4 ai ncw viruses. while tissue cultures =do it dLs~ possible to study their different reproductive stages. .n.evt,r, even the 1m;t method hat; its linitations, and they are doter- minvO by thw -~ologlcal d1mLinctlans of viruses as strict Intracellular pars- mites. initisitAcn-of virt:A Infection dopendB, or, the cao band. on the pbs,,ilbtlity of p,.,ncrut1un Gf v!rionv Anto the Lett And, on the other h.1rd. on liberation at their getetic =iterial from protective protein mtz~branes. The former 4ondition 13 dttermLetti by thL presento in cell membranes of receptorg with uhich 0-~- 'v=~%"t structures of viriong interact. obviously, 4 ~n ~hu cot4cnL of lengthy evolutl-~n, different viruses adapted to Intecaccion. vith difi~,.rttkt typen at cells and, for thlu raik~on, for cample. cobacco momaic vIroa dot.,s not,nurmally penetrate hiro the cells of warta-blooded imalu. The aee,~nd condition is related ro the presence In the cell of rot~vo.llytlc ~ntyt~as "Pabl"I of partially or completely digeitInIq the protein ct~mbrands. of the vlr~6 ~trid pertilt thuir,genctle material to function, 'hig LA-plairs 11by it Ab Voviliible to ind,,c. virus repr.durtIon In tells Lhat are %-..p not sentItive. to viruses by administration of viral nucleic Acid (Holland But even 4dninistvatiun of viral nuclaic acids.,b y far tkot All of hich hrve Infottious pco ortieu, Is not alvaya asaveUted with viral P k1holfirst par. of the wqrk'was performud.jotutly with,T.I. TWtonenko, B.A. Naroditvkiy,, and A~F. Docharov, on4 the second with G. C.: Miller. jao- .1 No abstract) 1/1 USSR ZAYDES, V. M. , VOLKOVA, M. YA., BUKRINSKAYA, A. G., and ZHDA11OV, V. M., Acadeniciaa, Academy of Medical Sciences USS]t Inatitu-V6"Vr'V WaT6kr,"I't-ademy of_~Xedical Sciences USSR, Moscow. "Sedimentation and Density Characteristics of Some Cellular and Virus-Specific Ribunucleoproteins.in Cytoplasmatic~Extracts.From~Chiclr Embzyo Cells Infected Virus" With:-Neweastld Disease Moscow# Doklady Akademli Kauk SSS. R pVol 1990YO 3 t 1971P pp, 219-221 Abst-racti Fractionation of a cyto-p1,asmatic extract from chic-k embryo cells containing labeled stable cellular na (H3 tagged) and vixus-induced PUNA C14 tag d) showed that both labolud compounds eadimentAid at the same rate NA5 Srand in the same density rsgion,(__J~IA g1ml). This suggests that f he cenuaIr and virus-speci:tic xibonuclooprotaina axe physically related. Such an assumption is consistent -with the resalts of N.J. Kaverin's func- tlona,l analysis of the vira.1 canponent of the hypothetical complexp which indicate -that vi=s-induced R11A cap. be transported frdm the 45 5 structures Alo~:-jwlyribosomes. This complex 48~.! re9axdeA as the initiator of viral protein USSR UJDC 576.858.?5.098-390'.332 Ye. A., BUKHRISKAYA A. G.,, and.ZHDANDV V, M., Institute of VLADDMTSEVA, 6ces, Virology imeni D. I. Ivanovskiy, IJSSR Academy 18?` Sci (ILoscow "Replicative Complexes of Sendai Virus" Moscow, Voprosy Virusologii, No 4, Jui/Aug'71, pp 402-406 Abstract: This st&-y was performed to verify the hypothesis that Sendai virus has two replicative complexes: one operating in the nucleolus and synthesizin.- viral RNA, and the other operating in cytoplasm and synthesizing complementary RNA threads. The tests were performedivith Sendai v-lrus zitra:~n No 960, -v;hich was incubated with Erlich ascites carcinoxia cells to:;which x,a iQ cti o pr,- cursors of RNA.wero addel. Sub.s.oquent,. analysis., rovaitled that the nuclear frac- tion as well as the cytop-lasinic,fractibn contained b6th bypes oft, RPIA, suggest- ing that the replicative complexes wer6 located in both parts of the cell. It was concluded that additional tesj-,s:mue. be performedby different methods in order.to resolve this problem co .1usively. USSR IJ W576-858-43 _337-11E Ma 0. N. SMAMrMA, Ye I., KOZLOTA, 1. A., K, 0 22 F and MM-10VI Y. M. I Academician, Academy of Medical Sciences USSR tiEl t cc rophoretic Separation of the Principal Proteins from Cell-, Iafected with ..Different Viruses" 2 ady A' -1228 Moscowj DoP_ 11 SSSR, Vol 190, No 5, 1970, PP 1225 actionr; in Abstract: Changes in the synthesis of total histones and'their fr, ribonucleic acid - - *, ri nuclei of infected cells and in desoxy coitple., wu studied. The accumulation and of changes in principal cytoplasm protein wag situdied dynamics of also. One hour after-Infection the number of prt.)tcinbands increases, maqt with Moderate electrophoretic zrobility. After 3 hre, additional slcw-moving bands ar, and this increase continues for 5 lirs.. After 7 ~hi7c, the Protein Uandr, begin appe rved to disappear, but various irdnor banda appear, AnalogouQ i-esults -w-re obae. 24 s after infection with pox vaccine, some increase with influen?.a virus and no f ir Y change in protein bands with Herpes virus. After 48 ars,: no increarc In tile pro- _.tein bands was noted. Me results obtained correapond to the dyqamicr~ of acciffada- tion of viruses in chick effibryo tissue. Four histone fractions -were isol:-ted from infected tissues: lysine-rich histones - fL,, relatively lysine-rich fractions f2a L2br and a fraction rich in arginine f3 . Electrophoretic tinalysis of indi- U -frac t1o, nuoun (1i Gf Iya,'ne-rich frnctior-. n-n- showed t1int a Conti nappearlmce j. USSR MC 576.311.1 URMkYEV, L. V.t DERMCHt YU. S.p HDANOV, V,. 14. o and YE,93Fovo Fe 1.1 -of Hedical Sciences WSR Institute of Virology Imeni D. I. "Structural Proteins of Venezuelzu Equine Dicephalomyelitis. VU us" 'o 3. 1971 pp 92-96 Moscoup BiokhIp-tyat V Abstractt PaIyacrylaxlde gel electrophoresis revealed that- Mghly purified VEE virus contains three main proteins. Tho ribonuclooprotein fraction isolated by centrifuging virus destroyed by tween and ether in a pexforued cesium chloride derasity M-Alent (1.43 g/0) containod a plotein with a molecular veight of 59,000 to 6ltOOO* The zore mobile: heWSlutinin protein ho4.a jaolectlar weight of 34,000to 384000.:,: The; fraction. wkich my nproaent -baial wabneune.protdin had a moleculaX uelghtof 15#QQQ-.to t8#000, -7 U= UDC 5~6-858-5-095.6 ZHDAKOV. V. X. and BUKRUSUYA, A. G. Reproduktsiya ~Aksovirusov. Virusov Grippa, I Skhodn3~~4i s Nimi, (Reproduction of Hyxpviruses. , Influenza and Influenia:-44ke Viruses: Moscow, ulleditsina", 280 pp at4 Trans-3 -on:, Annotation: Achievements'in molecular biology have spurred the rapid development of general virology, :thr..:most.urgen-7t problem of which is the -of Viruses Amo g;the RNA-containinga, viruses, study of intracelkilar replication n myxoviruses , red and therafore.has become the replication of is least Uqlo object of intense investigation in recent.years,. As ::a result, numerous form- arly unclear questions I ve been explained In addition, problems deziandin" na v further work have arisen. The book presents mwdern, conce.pLs of the machanism of myxovirus replication. Two intrcductory chapters~:of the book deal with L. ief '0 problems of mp~ovirus classification, atior aokgroLnd treatment of myco- viruses, tbeir structure, composition, and physicochemical properties. A section on Inhibitors of nuclaic and prote-in me.tabolt.,sa supplements the pres- entAtion of.the main material in t4e bo6k,,'which is: taken UIP in the following order. 1. Ad.5orption of viruses on cell surfic'es. 1/3 USSR ZHMOV, V. X., et al, "Aeditsipall, 280 pp 2. Penetration of virus particlesInto cells.: 3. Deproteinization of virus particles;. relz-a.se of viral nucleic Lcid and its transport to the site of ~replicatioa of: viral iLNA Preparatory (early) virus-i uc6d: syntheses, 5. Synthesis of viral nucleic ac:id.-.- 6. Synthesis of structural proteins. -d` f rom cells. 7- Formation of mature virus particles and thbir e Because the subject literature cantair, no generalizations of accumulated s material on- myxovirus replication. the bookwill be of interest for virolog- ists.working in this field. Table, of Contents: Page Forevord Chapter 1. Concept ot Hyxovixuses 7 Chapter 2. Structure and~Chexic;al'Compoqition of 2213=viruses 15 Chapter 3. Adsorption and. Penetration 1:8 Chapter 4. Brief Information on lakibitors or Nucleic Acid and Protein Synthesis 88 MR 7RA 7 ~6 ....... 1DC:5Z$05.8.75-.098..,/7 .33?: . . BUOD5MYA,, A. G., AND, SITO, A. F., Institute of Vi 0 rol gy Acadeny of'fledical Scie~ 'es, 1,10scow imeni D. 1. Ivanovskdyv U "Characteristics of Sendai Virus RNA as Studied in Polyacxylanide Gels" Moscow, Voprosy Vi-rusologii, No is JmAeb 71 S Pp 77--~l rUZ Abstracti Viral and virus-induced FNA of Sendai vi (st�sin No 960) was stuclied by electrophoresis In polyaGryl-azdde eels, L;a~eslirg with 10 - or 14 C uridine was used to evaluate the molecular uelgh.6 of various RNA forms. Cloase to 10 RZA forms (rulecular weights rangftng fxon 170,000 to 12,000, 000) uere discovered in cells which had bosh infected, by Sendai virus. knong these were a newly fo=cd r1ral. ZAf a replicative form, a replicative inter- nediate form as well as R11A (molecularaweight of tho:bzder of 8,~00,000) occupying an internediate position betireen ~the yimal wid the replicative form. ral JUIA;i with nolocular weights, below that of viral IT -ze found. Sevc It is pointed out that some of:the gal;Traction~ roport~ed may Consist of 'impure materials or of degradation products- TJSSR 576.83.$.3.097.2-077-3 CHEPUMS, G.-K. S. o ZHDANOVj V. 1W , 1.0 CME 111BA pI*, and ROZHAy K., Institute of Acadeiiy.'of PladleaI Sciences USSR, Floscowt Institute of Hicrobiologyj, 1,1edical Univorsity, Hungarian -P66plels:Republic, Budapest, and,-14icrobioldgical Scientific Research Group, Acgidew of Sciences Hinivarian People"s Reptiblic. "Detection of Cellular Antigens in liyxoviruses amd ParwWxociruses by the mmmodiffusion Hethod" Moscow, Voprosy Virusologii, No 1, Jan/Feb.?I, pp 62-70 Abstracti Sevexal types of ir-mmiodiffuzion methods which -so far had baen used only in the study of arlanovirim-es plant viruadap and. a fen othe Viruiar, wero u;ued to study the aritir5anic comPOW.tiOn Of myl:ovi=03 ani paramyxo-druses. The nothods used wera double -!,el dAMsi6n I immuno- electrophore-zinp and 1tn;uno-o-.mophoxeuis, The viruses included in the sturly vrere Group A Hong Kong influenza virus I foirl plague virus (strvAn Weybrid~e) Group A influenm vir-us (strain WSN) and A vi--~w ($*train Engiand/64 and Hong. Kong/68) arA H .;,aastle disease virus ?stra.-In ToriUnskly and Hertf shire) and Sendall Yi=s (strain No 960).~ The virutes~'were cultured on chick embryo cultures and primary cultures of chick f1broblastsS The viruses stare USSR CIMULIS, G. -K. et al., Voprosy Virusulogii, No 1, Ja:i/Feb 71, pp 62-70 purified by colutm chromatography -with EL special cellulose fiber material, andconcentrated Irl dialysis of purified preparations -gainst -polyethylene glycol of moleculax weight 6,005. S- and Vv" antigens.ifere obtained by washing the virus 'prepanations ulth etherc Virus antigem were sepaxated by adsorption and elution. Viims-specific aftUgans mi--re datectet! and also several.celluLar antigens Included.in the.c.amposition of v-1rus particles. Three of these cellular antigens were ident1fled as group A species- specific, andForzman antig-ens. It was esti*lishedt~hat th; c;llulax antigens are located not only at the sLxface of the virus particles, but also in tlle- deeper structures of the virus particles, Also' experimental data. indicate P that cellular antigens axe not simply MchaAiaally -~c Wxad im-purities rathert they are- essential conponents of..the virus j~xticles. 2/2 6,3 2 1 PRi UNCLASSI F E, OCESSING DATE--23QCT7Q tE--ELECTROPHORETIC SEPARATION OF Tf TT _6ASIC~PROTEINS OF CELLS INFECTED W! ~l DIFFERENT MUSES -U-,-, _-AU'rlH0.R-(05)-.8EREZ INA# :0.N.1 SKLYANSKAYA,, YE.I., :.kOZLOVA,I O.P*l 4HDANGVv V.m. COUNTRY Grnwrr- U S S R SOUPCE--DOKL. AKAD. NAUK SSSR 1970t L90(5) t: 1225-8 VIROL '.DATE PUBLISHED ------- 70 .SUBJECT AREAS--BIOLOGICAL AND MEDICAL SCIENCES --ELECTROPHORESISt SMALLPOXo VAC TOPIC TAGS CINEr IN.FLUENZA.VIRUSy HERPES SIMPLEX VIRUSt TISSUE CULTUREr :PROTEI.N -CONTROL MARKING--NO RESTRICTIONS DOCUMENT CLASS--UNCLASSIFIED PROXY REEL/FRAME--1999/0704 STEP NO--UR/002.0170/190/005/1225/1228 CIRC ACCESSION NO--AT0122790 UNCLASStFIED Ijms~fflm .UNCLASSVFIED~ :PROCESSING OATE--2_AOCT70 ilz 021 7RC, ACCESSION NO--AT0122790 c GP-0- ABSTRACT. ELECTROPHORESIS IN POLYACRYLAMIOE GEL WA'S USED TO FRACTIONATE CHICK FIBROOLASY CULTURES GRONN ON MAYR ICES 'WITH AGON. OF BULL SERA OR ONTISSUES FROM 11 DAY CHICK EIMBRYOS, THE INFECTION WAS INTRODUCED INTO ALLANTOIDAL SPACEr AND E14PLOYED THE V!RUS MATERIAL OF SMALLPOX VACCINE* INFLUENZAt OR HERPCS# -THE*TYPICAL ELECTROPHOREGRAMS WERE SHOWN FOR THE TREATED CULTURES; THE CHANGES IN THE ACCUMULATION OF BASIC PROTEINS VARY WITH OURATION,OF THE EXPT. WITHIN 1 HR OF INFECTION TO Nq. OF SEPO*. PROTEINS ENCREASES M-51i"ILY IN TF THE 'GROUP OF MEDIUM ELECTROPHORCTIC MOBILITY; 141THIN 3 HR, PROTEINS SLOW MOBILITY APPEAR AND BY 5 Hk THE BASIC PROTEIN' FRACTIONS EXCEED THOSE OF THE CONTROLS BY A FACTOR OF 4 OR MORE; BY 709 HR THE NO. OF DISTINCT PROTEIN ZONES OECLINESv BUT MINOR ZONES~~APPEAR AT THE TIME,. THE INCREASEDJOTAL AMOUNT OF BkSIC PkOT8INS IS CAUSED BY INCPEASED FRACTIONS OF HISTONES RITH MODERATE LEVELS OF LYSINE; lY IS PROBABLY THIS PROTEIN FRACTION:THAT IS CONNCCTED~'WITH THE INHISITIING -ACTIVITY OF-BASIC CYTOPLASM PROTEINSo. UNCLASSIFIED USSR UDC 576 858 Academician, Academy of Medical Sciences USSR, YERSHOV, F. I., and UMVAYE-V, L. V., Institute of Virology ihLdnt D. L lvan'ovskiy, AcadarV of %Medical Sciences USSR, Moscow 'Formation of 'Pseudovirall Particles-in Homogenate Gbtainea from Non-Infected cells." SSSR, Vol 1139, No, 4 -op 882-!364 MorCow, Doklady Akademij Naul, Abstract: MIA obtained from equino encephalomyelitis virus vma added to fractions of homoGenate obtained from chick e-ui~ryo Pibroblasts'. PrOparations were Incubated at 370C. Sanq)les taken at hourly intervals were studied lmd titrated for Wee- tiou6ness. After addition to the non-infected homogenate the viral FUIA undergroes -a transforration. It. envelops itself in protein of the: nni7n! chicken cell. It becomes a "pseudovirus" in changed clothing, capable.of-infectiolis processes ano plaque- formation,,-with only one difference from the: matiu,e virus. The jrature virus iB. insensitive to RiA ace, -where" the "Pseudovirua" is only partially _ins6nsitive to this enzyme. Zie new- "chicken elothinj' has gi*ren it some degree of protection against antiviral actions* UDC 576.858.25 USSR YERSHOV, F. I., CHEMETSOV. Yu. V., and URYVAYEV, L V ZUDANOV, V. H. A. F.,1759'Mul"Mf Virology imeni D. I. Ivanovskiy, Academy of BUKOVSKIY, Medical Sciences "Sedimentation Characteristics of Venezuel an E quine Encephalomlyelitis (VEE) IrUS Moscow, Voprosy Virusologii, No 3, may/jurl 70, pp 330-336 Abstract: WE virus was cultured in chick embryo fibroblasts, concentrated and purified. The optimum method for obtaining b iologically active virus components consisted of destroying the virus with ether and Tween.,' Purified VEE virus sedimented at about 380 S in sucrose gradients, the nuclei at about 160 S. Cen- trifugation in CoCl gradients allowed that: VFF,'infqcti*ujj matarial bands in two main pogitions: most of the virus: banded and aiDmaller vmt:iunt at 1.42 g/ml. IrIle main peak of hemagjlutinii~s W"as -d6tecte,d: at it buoyant density of 1.25 g/ml. USSR UDC 578.083 HDANOV__Y__x_ Academy of Me ic Academi d al Sciences USSR, SITO, A. F. , and I)ERKACH Yu. S. Institute of Virology iuteni D,~L Ivan vskiy, Academy of nces USSR, Moscow Sale "Identification of the Information RNA of New6astle DI~L'Iase Virus" 'Moscow,- Doklady Akademii Nauk- SSSR, Vol 193, :No 11 Jul/AUg 70, pp 211-214 Abstract: The specificity of virus-induced IWA was studied, using cbicken fibroblasts which were incubated to determine the. canteut of 18 S-RNA. A portion of this preparation was infected.with Newcastle disease virus and subsequently treated to remove the virus and isol 'ate the. MiA in its pure form (18 S-RINA). The portions of 18 S-RNA obtained frPm noanfected and infected cultures were incubated in a protein-rich-medium; la S-RINNA from infected cul- tures induced protein synthesis more intensely than that frcm acninfected cultures. Subjecting both specimens to varlous scientific u,!.qLs showed that: the RNA isolated from the infected portibin had a specUic ef feet on the. for- mation of its products, leading to the. coincl' ion. th : :'it is the iufurmation us It: RNA in the synthesis of ribonucleoprotaifts '(6-ant.igea) USSR UDC YERSHOV, F. I., URY'AYEV, L. V., and Z11DANPY1-1L_1 Iiistitute of Virology imeni D. I. Ivanovskiy, Academy of Medical Sciences. Us.TR,. Mp~cow Ifsynthesis of Infectious Ribonucleoprotein olf Aebovirusies in Subcellular Struc- tures" '130 Moscow, Voprosy Virusologit, No 3, May/Jun 70, pp 322-, Abstract: A mitochondrial-microsoma.1 fraction isolated from chick fibro- blastainfected with Venezuelan equine encephalcmyelit~ls virus (VEE') and incubated in medium 199 ensures extracallular sy-Tithesis of virus-specific RNA and protein and the formation. ofs xibornucleoproteirl complexes (RNP). These complexes possess infectious actlvity,. ~ifii* increa!%,40 80-10O.-fold in 3-4 hours of incubation. The "WiP complexes contain the infectabous RNA, which atay be associated both with the virus-specific and the cellular proteins. The main part of the Infectious-RNAis.formed extracellutarly ~nd not because of CMVIetion of the templates derived from"ceils togetb*T With the MM fraction. ----------- uSSk UDC 576~'85MM95.383.098 ZHDANOV, V. M. YERSHOV, F. 1. , and URYVAYEV, V., Institute of Virology i"EMEETTOmT. LVanOVSKIY, Academy of Medical ~Saiences Mk,, Moscow "Virus-Like Particles Formad in vivo and in vitro" Moscow, Voprosy Virusologii, No 5, Sep/Oct 70, pp 537-5143 Abstract: It was shan that ribonucleoprote-in complexeii capable of producing hondrial frac- infections and typical plaques in agar were formed in.the mitoc tion isolated from cells infected with Venezuelan equine encephalomyelitis (VEE) virus during incubation in proper 141'edia:. , Sedime. ation constants of these complexes in a linear sucrose gradient~ranged from 809 and 1605. 'rheir buoyant density in Cs gradient varied from 1.30 to 1.42 g/C!113.: Virus-like particles ("pseudoviruses") with similar~characteristicis wera found after addition of the infectious RNA of VEE virue. to homogenate of, u, infected cells. Theze particles were partially reeiiitant- to ribonucleaae and coild not be neutralized by virus-specific sera. It is proposed that tha formation of virusa-like particles in vivo and,in vitro. is,based on kome conplexing between viral INA and cell proteins, in which case it is pos4ble that formation of informosome-type structures may occur. 212 013 UNCLASSIFIED --049EC70 PROCeSSING DATE IRC ACCESSION NO-AP0137194 AaSrRACT/EXTRACT--(U) GP-0- AgSr RACT, rHE FORMN'T1,11M Ili: REPLICAT!VE: FORMS IRF) OF SENDAI. VIRUS RNA IN VIRUS INFECTED CELLS:WAS SrUDIED. SEVERAL MINA SPECIES WITH -SE011MEIlil-ATION, COEFF;, OF 7 S TO 48 S~WF',~E REVEALE0 IN THEZOURS OFINFECTION, AND:A CERrAIN SEQUENCE. :114 T~IEIR APPEARANCE WAS VIRUS RNA-WERE D`AS;MUL'Ti[5TR:ANDED REPLICAVIVE )3B50s.- RF OF SENDAI f 0 V N :1. INTERMED LATES ( R I ) WITH SED IMEINTATION~ WEFF. RANG1 NG'FROM 20 S TO 30 st AND AS DOUBLE STRANDED RF WITH A SEOIMENITATiON CbEFF. OF ABOUT 22-23 S. PARENTAL RNA WAS FOUND IN THE INTRAINUCLEAR STRuc7ruRES AND IN THE .:CYTOPL.ASM. PARTICIPATION OF PARENTAL~ RNA 114. THEi FORMATION OF DOUBLE STRANDED RF WAS EVIDENCED. -FACILITY: D. :-I.-IVANOVSKII INST. :.VIROL.? MOSCOW, USSR. UNCLA SS I F M:):~~ 016 u,4cLASSIF'I[-D'.'. ~~ROCESSING DATE--30OCT70 ;:'T-ITLE-SYNTHESIS OF INFECTIOUS RIPONUCLEOPROTEIN OF ARBOVIRUS IN 4-SUBC-ELLULAR STRUCTURES -U- .-,:AUTHOR-(031-YERSHOV, F.I., URYVAYEV* L.V.s ZHDANOVV V.A* "Stu" -CGUNT RY OF INFG--LSSR OULZCE~VOPROSY VIRUS-m-.-'.;I 11970, SR 3 PP-322-3 130: PUKISHEC- -TO ~.S-UBJECT %RaAS--'.~T0LCGlZAL AND MEDICAL SCIENCES toP I CTAGS ARBOVIP'j-3, VENEZUELAWC-QUINE EN 'CEPHALITIS VIRUS, RNA, CULTURE MEDIUM J."UNTROL MARKING-NO RESTRICTIONS :DOCUMENT CLASS--UNCLASSIFI'U c ~PROXY REEL/FRAME-2000/1847 STEP NO-UR/040~?j70/00"/00j/032e'/0.330 .CIRC ACCESSICN NC--AP0125458 -11: IED- UIN L A -1) S ~2/2 01.6 UNCLASSIFIEO PROCESSING DATE--30OCT70 .6 Lit CACCESSION NQ--AP0125458 ~~.'ABS TRACT/ EXTRAC T--(U1 GP-0- ABSTRACT. MITOCHONDRIAL 11-111CROSOMAL FRACTION ISOLATED FROM CHICK FIBROBLASIS 114FEC TED-~ ,ell TH VEINI~ZUIELAN E-Q1LIANNIE ENCEPHALOMYELITIS VIRUS IVEE) ANO INCUBATED IN MEI)JUM 199 iNISURES :~:-:.EXTRACELLULAR SYNTHESIS OF VIRUS SPECIFIC RNA ANU P,10rf-[i%S AND FO.RMArION OF RIBCNUCLEOPRITEIN (RNP) COMPLEXES. THESE COMP1,1EXES POSSESS -:-INFECTIOUS ACTIVITY WHICH INCREASES 80-100 FOLD 114 3-4 HOURS OF '-~1NCU8ATIGN. THE RNP COMPLEXES CONTA-IN.: LNFECTIOUS~~RNA. WHICH MAY BE ASSOCtATED, 13OT14 WITH VI RUSS PECI FIC.tAND (;ELLULAR Pl~~[)TEOJS, THE MAIN PART THE INFECTIOUS RNA IS FORMED EXTRkELL'ULARLY AN'O NOY. AT THE EXPENSE ..OF COMPLETIGN OF TEM~LATES DERIVED .'FRdA THE CELLS: TOGETHER W I TH 1411 INSTITUT VIRUSO GGII~ IMENI 1). 1. No FACILITY: L AMN SSSR, MOSKVA.