SCIENTIFIC ABSTRACT ZBARSKIY, I. - ZBARSKIY, N.A.

• Document Type: CREST
• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R001964210001-7
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: March 15, 2001
• Sequence Number: 1
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

77
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ZBARSKIYP 1.

- - - - - - - - - - - - - - - - I - I - - M~L-.v - I- ~ - -, ~ ~ ~ - . - - . ; ; ;I
1401 0 0 WWI IN Is w Re a qp we (wow Ow-f-W-0-0 ; a
1w is a so a is v a 0 4 of 41 a a*;C 0
(XI60i A" off*101011 .Ord
0 'Mi distilbution at amiao adds and pol des bd-
and On= 12
tween erythrocytes
:9 1. ZNII phyl,I)l. (U. S. fj. R.) 27. ZW-Min
- 1,L~ ).-Wen"jonly h&4 no noticrAblu
09 ptlgj&yj,~ _Nh M,
ffect on the disinbution o1 amino acids and polYPePtill-
Crythrucytt5 slul plamlia, S. A. Katials
00
63
00
C30 o
00
1 4100
so a
see
zoo
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too
SITALLURSK&L LIT99AIVRC 4LAWFOCATICY
RICK" lau.i ma.inv
lonov* -4 .3.. CIC
IWILIBIMACI Cm 0.1 1$1
u a a RD C4, 29, 1,. M, PLO no An 1 0.0 W 2 1 If If Ia -y-
000solo t f 73
0 * o a o 0 90000 a 000000 0 0 C el
0 0-0-06 ISISGO 0 0 a a0 *0 00 0,
0 0 0 * 0 0 0 0 * 0 L 0 0 40 0 0 0 0 a

4D U J vj IS 14 V it It V 'I J2 it
0 4
6 taws of Ma =4 "Laws.
" a. v. Bkk-
9. lot-15jit44), t!p to ww,,2o vikly It&% bm
na4a of the amino acid cotopu. of tht toorA4wai tW44,64
04 V. i u# a buffAM at rinfnW orpa oc Ouua. The Wowing 0
ainitio ackit weft skid. In, nom "I
lRbits Ink-0 - usittine"=Ct-
00 Iffitte, vNise,
4q OUGIbitted pCotch" Mr.
I u ta-1-14.1tice r"falfs WMV argifthm Obit"
04) of ane"Ma Orpai of Saremm 1"WA01" Calwerxi
"MILUnk PtOWP14 V10141111 k0l rMIRS Moo the protein* 01
0o arc rickt, 1u crstine thaa ore notnW tW t4mcr fif(At[M.
The antino &M compa, of the tont!AnW pMciw tA tuouse
Ca"Vir and sarem& Is unifonwy const, am C*AuKK tM
0 altered by 1n*llWs of argbOsse, histidim or line.
P, "9161,
"I
im
o-
a a IA I
1) Uin AT 00 is T-V An a
it 11 IF 3 it 0 it W it it it ft [-~ a a I W so a 42
AD n I id
o 0 O~e 0 o o * 4 0 0 * oto 0 0 0 0
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too

.1 W qjp w 0
a0 a All As a if v x Ali a At a d a ago
Aw
flaccitst A09 0owlefits mut 9
::~o A efflediddem, 1w
FAqw, 144.
famLm
00A .
watum9cif
~_Ittpts. wt.e cnrrw -1
IM MA0044).
s
N 00

60_ o.
l
.
wirf to drd out thili rok Of at[11841 tkm*'O
III
to * Ite mkv -00

0 .
"M s
Wor, I itc. mind k6tid,".
C E It, - tim
C Fh,
I- I pgjved
I te VMS mot jitima.
d
-00

'00. tbeo
y to Is
k" Ad U
-o 0

ax~mimi. The dite"Vency way be due to the fact Ihal -00

0 0,3 G. used vinether tuaw strign (St 61) "1 Lai "aluced Imp goo
quantilk-3 of argirdne. G Urny al"y oart"I th~
f
h
f 200
a
ter t
e arl"rancr o
%i%RvIr luirkirs. S. (1. M.

AD 13 no 0
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A_ 611TALLUNGICAL WERAT&WIt CLASSIORKAYMN
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020

ion liwelavo 1
~ Z-A
likilli site wAV am
P A a nd d
In 1. 0 p a III Ig axIt If %1 11 ti ig
1A
0. Wele 0_ *_*Lo 0 00 00Ab GLO 00 00 0 0

(k 0 0 4p 0-0 0 0 0 40 AD is 0 40 -

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P I IN a 5 a If

0 AD III
0 0 0 0 0
: 0 0 0000
0 0! : 0 S 0 0 a 0

M.9 Is W
04
-'so
oi
OOA
Past do andysis at (hit umd cotetas in cuc9t. -60
*O.S YbMaNoff 4
ad 1. it. Iff'plaff (=. Red. Mawo").
Mat. Mcd. Z4, No. 1, 2Z-5?9947). d.'
Ow a .00
o .. 0rdicLl!.W'At. S 3148'. 63MI; $2, OMP, Ad4 Union
ON Inter. Contra Calurm"I 3. 1XIM.-In 00afirmatim of
oe Wevims work it was fountl tW the saums of 20 of 24
palkats, with caum, aye sm- catalytic *am on
tban ds, the normal coutrob. Serums of
==elyu with other disnum also pvv poo. rutilts.
Proteins eztd. (rum the bloW a( rabbits bem%S Hcown. a goo
Peame carelmomas with 0.1 S AcOf
ar "--VcsW'ly =O*
higher waves than were famd in
_PMmible'djuifimAnce of the findings is discussed.
Eucem licherts
A,
,.s
00
goo
100
Noe
ISO
U00
WOO
I 'A An L S 0 fW a m it In I a I I
'F Raw A I x a
u Tl AV, As tip tr it CP J It
0 0 00 00 a 0 or 0g *a goo 0 00 we 00 0 0 0 0
0-0 0 00 0 00 g

I A 'a
0 of 4 41 jai a 40 0.
*0 A L- --Vget~--
Watse-edublia adwilWaliblPh-PhACASO Ill 1189tuill And
in -11-tint daut. 1. B Auslikil ami N. A. Itsislicy
(CcatrAl. Oncologicul 14.4hi.iya 13,
nutrkcd difference4 wirte found In thr
ittrit, of atirnosimtOphospharaIc (1) in vArkma inAtiltnant
is 4r. a tumors and in, nurva4 tknisutt 14 talce and r4ts. T%0
Pho"Ibatc groups wCre rcri-OTC-A (cum
pbstebyl. ne optimum pit of I wx.77.0-7.2. Attill .00
11.0, the activity Aas about lullf. and at pH 3.d, prAc(Icully 8*0
Airfo. Aq. Solall. of I wriv itictivill"I fly 0,101 M Mt kilt..
The gtvjteqt activity of I wd* Nall'I Ill 1114low alit! ral lIvIr,
coo
oe 41
coo
t coo
(Zoo
it 1 1140 0
No*
IP
El _a - 1---
IV's 0
It *.V 4of
to two 4 Illrelf,
U, 4 AW 00 "1; vat,, not itst mettv TV
0 0 0 0 444,
116 See
Goo*** see* 006/11/
N -

. ~* 0 * NOW 0 - - - - - - -
01 010 - 0 .0
1 1 19 11 ts IT u is it it ~ 14 11 x 21 23 Is is x it IT 11 14 0 is u
A-K, P.-A -A.- __L_
Some propardes of patting of Velluw nudel. 1. H
0411 Zl 1 K. A. Pekhrdy t IF. -It
-Ir s.S.R. 60, (Imit hinnall
du
hVVr frils werr Int"t miatisfaciswily em,laird fly 114lig it
g litiffirf at lift w1kich V4111CIS ill ill(' Add
-lite linclel lite undatustavil And Late (tiv (if rXitikilrOiM 1114.
terials. Emn. Tilf the tiuck-i by Af NaCl k4l tit "tit. (it a
luldroprotein. which was wiml. into iteaxyTill,ornicivie
avulatulpflitrill.
11411 and i% ftVV 44 Avid And 1111prills 1.1
*1 N IRA Irmilit'l
livAlliolrin. Flifil, lit I lie 1111010i wilh 0.1.
in olu, 0.1 A littlivill 11.1ying hiallmo Inollillir" lilt, e%1
WAq sillit"lly SAI will Allyr is 1114, oil l1w lool"Ir.11C),
which fill
not 41154olve Ina 21-hr. dialysis anallml water.
wait sill. fit 0,05 N llCJ ta"nitte a OwtAut wilu.. u,is plail, ego
by.N11,011, And wair fretral (typlaithan. it ointamol 17"j:
.**U N and Under 2r 1 1'. The fictiAttollilts"ir-11101 wtht. lilt its-
irction ~ into$ w
Mrr ITAVe jirlmill.1114 111trad.. which "$tit
shjvvptj Qlafl, tI.Ingaefiell. roe
* )" Ali'[ c4cf, gave
Vcry 1.1w Conclis. (if SAC1, KC1. Xfg.Y
only -411;111 Ct"Itructious, white 0.01-411 Af concus. gave
(hiv.4lent wIts Are Inote 1%itrill), see
t- cauwshlitiai swouips. then A shrinkAgr
I
cullimetims in plimphair lwn&f~ Autwe'l
I llult it laket; place at fill valuei tlvvr 'I'S alul Tim's With
rising fill. The histulle is wi. in 31 soluit. of \Act, KC1,
R-01
CUCI,, and Nlff.90j, G. M, KOSOIJIX)ff
I A t VR G K A LUTIRAJDAL CLAWFkAT1Oll
$Mll Sill"
aa C.,
lit
.11 C.. it
-; -'k- j -.. i--T
An L 4 rw 0 4 0 it so 13 a a 3 1 41114
U &V 00 111% it t? tv to OV 64 19 41 9 91 it it it at " I I
1 0 0 * *,* 6 0 0 0 0 * 0 0 0 0 a 0 & 40 40
009 oleo 0 0 0 0
o so
V=77777-

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i ~
4
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:~5
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tr W_
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go
SSM9___ _I 0 ko
$.Dt*
I
00 _90
0 FftW= d C40 dwec 12 -00
V S. S.
V _Ceu
now 104d. 1Y49k 5z A A SOM). .00
oo nucki ?1~ hurnan UM, Mt liver. Mit sarewa No. 45.
so jjnd calf thyroid met belated Sit pill 6-4,2 according 10
tise intowd,of Z. wId Pexevothehikoft (C.A. 4z, Gum).
_11le fluefet)Vtoftiull WVM Wd. by At XACI and centrifug-
ing.. The nuckar nucleaprottin so obtalaM was foutul to ~416
cors"poad to chrotaosin of..NWAy.and PoUlster (C.A.
'go 41, 1271c) in iti properties. The residual nutter ts; still 1041
protein In Ouractit r. but Is almost devoW of P and 6 vts .00
-E SICK. desarydboutOdc " test. It can be Isolated by
cxtu. with 0.01-0.05 Y.NaOH and is a protein a( we-Akly 600
-ucidic nature with lsockc.pt,at pill 5-5.3. Reavivalot
Soo this still leaves Whind a protein fraction which is inwl.
I" any of the usmJ extn. media and %wells Its aWall. Such 0
.3 of 3 protein types can be done only U the ntscld were coo
ied sit u"r-neutratity; use of acidic nialiA lmdj to
0 O_.U i partial denaturation. The suckoprottin w8prises at 0
ow wou but &)% of total nuclear protein nutter: the acid
protein ntay be present up to 40% (samom) o)r WS71c
(fiv" sw0bens). The acid "tin cootalru alxmt.
-Irypkophan 2.5, tyrosine 4.5. arginine 7. lysine 7. h6ti- zv 0 ,
dine - 3. glutamic, acid 13, asparfic " 6, cy*tinc 1.2
methimine 3, and V OM170.. The insol. jwmcin has no
I ! BA, lyllue 3.0. tyrodne 1, clutantle
tryptophari, of I W,
acid 13, astwtPwid 6, cytim 0.3, .thirSaine 0.6, 1
0. M. KOWUPOIF 0
SL
Ii
TALLU (,ICAL MINA1701 tLOSIFKA1100
R tie*
14"0110 ISM103 wAr Of 009
IF 1 1 a il I
11 An I s a rw 0 1$ a I IF IS 2 a Is 1 9
W It V a It OF IS Or aOt 19 It Cc it Of 040 a
OW
00 000 go 0 0o 0.0 0 0. 0 so a 600 0 a
0 0 0 0 0 0 0 0 40:0,e 0-0 00 lee** 0-6-0 0 0a 00 0-0 0-10 a 0 *11

ZBAPSXIY 1, 9,
USSR' -(600)
"AmAno Acid Composition.of Albumins in Swellings and ormal Himmn CTgans. Vesis for
degroo of Dr, Medical Sol. Sub 9 I~ay 49sFirst Moscow kder of Lenin Medical Iwt.
-JWSummary 82,18Dee 52, DiagertatOn Presented for fielmees �clenau and Enpineering
In Mosogg. In From Yoghommik #941-k"pJan-Dec 1949,

i
i , I
i .. ii
i F
i I
I
11,
I .~* ~lni
I 1 11
I~ , 0
11 1
I ~i
.~4
..rj% :
I I f
IIP,
I

ZBA=no I J.
Chemistry of call nuel"i. tropekhi Biol. Khiia. 1, 91-114 150,
(CA 47 no*14-'7007 '3)) 041;x;L 3:8)

ZBARSKIY, I.B.
Amino acid composition of tumor proteins in man. Vop.med.khim.
3:157-164 151. (MIRA 11:4)
1. Biokbimicheaknya laboratoriya TSentrnlinogo onkologicheakogo
inatituta im. P.A. Ge'rtaena, M6akwa,
(AMINO ACM MWABOLISH) (BOIMS--TUMORS) (SKIN-TUHIMLS)

contract"t Propertlec of Coll nuclei proteins 1, JU
Zharsol ;ind K. A. Iletrvo-hchikovii (Cenfral Oamh',git-J
IiM.-' Wokh miywj 16. 112-240M1). 0. CA--
42. Wlf&i.-Nuclei frtun human tissue %vre wpd. front
IrYtOllIASM fly Citr3((` IJutTcrOf IOU tit the
va%r of rat %arcoma. (1.111A .11 Orate buffer of fill 0.1-41.2
x~ employed. Couiplete details far ihi nuclei scluis. are
gi%-rn. - the InCtit(KI i% eerArffC%f MIS *Uperlor to th.st worked
cult by Douncr and fleyer (C.A. 42. NVAO. The histone
was extd. front the nuclel with 0.24 A' 110, by Ktvwl'%
methoil (Z. ph liol. Chem. 8, AII? IX441 ~ 1. Vie hich
ity shown by Colic vthm wa, a pru)x-rty fif tile procrin
itwIf. and was not cius"I by inipurith-s of ouclele ILCill.
Fly blawing the viscous hi.,ranc, ~111. with a Olpillary Pil,et
into ttWd. water, or Into very dil. salt oln,,, jellylike
hr"Is wcTe obtaincil, fit coumist to the actomyosin
iWads, the h1vone threads wi-rc ow ria,41ir' The Jailer
Aarply MitfAC1941 ililtAiSC and feligibMw whi-11 plactil
lit it 4nln. of 0,001 31 *%a aileno~inr triphoslihatt- (ATII)~
Salt Wins., 0.1 M. the lanlefIrKrevol' I'm-
trucl'ou of the histotte threa&, hot 11.11111 .11 -4ilt oln,~
cuum'd 0111Y q slight contraction. Thr uction of ATP (")it-
trucrion of himone.thrrasl% to Lit% of their original length
in DO)l At ATP will.) 1% therefore regarded it% %mitic.
116tolle 111tvalk front livtr lulclei that 114441 clultrArtid Its,
tile adion of MI .11 K0 relliffiril 11) their utighlal ivnil;-
tion when plactst In distil, watcr. Threadt; coulracle-I by
oJOI Af AT11 t1iii not awril nib agAn in diod. water. lli~
tone threado front nuiltImint tunmirt. rutitr4oril nuor tivitily
And to Ig I~ d!il'ist thin the (hre;V14 froul lit"fail t1". U"
Crilike aclornywin. file covittartile nuclei protein &I not
-ae a, The anihm u6i comptt, of
ctivity.
is on;t ATP re lkitill its 2 talil",
and total nuelet pratcho -a
It Is Suggestell that the contractile PtojWftlcS of oliciri Iniv.
lcins play an Important part in the userbinkul -,I milmi.-
Pfiv,tlcv

The 004w# *4 We a"UP40o "bvW" in me oo so,
4 it Ki A.
4., 9, Jil- MI)i , U,f,
(r" of Ityptophals, it oul. 10 It$), 41 lily toi, 44 O.DS41.6
At NOCI and *#*)A W. 6104-1.4 MCI, "* twatrifI4
wparme(V krow Without effitt. Ttio voistwillp ptirivin can
fit prriml. fly M141fif the Mitotic and Owfil protchl Isom the
cell fluttel of the wife or different organs M Man anti sini.
mah, or even by irdsing the nuclei of diffir"ot organs from
diffemt AnIMAIS, - It one or both components d the corn.
plex Is derived from the nudei of m0griAnt tissues, the
threads low" Its# contractile ability. "a ack] protein
of the "if siuctel cAn be replactif by a notiffuclear. cytorJas.
mic acid prottiu. A contractile protein is obtained by
ronshining a liver histone with egg albunsin. If. P.
/Ay.

ZBARMIY,I.B.; IMBOV, S.S.
Protein fractions of call nuclei. Biokhimiya, 131. 16. 390-395.
(BA - A III Kr 133-.267) (MLRA 4:101
I ..

Yj A
C080"t of MUCOP01*4ccloaddooss and mucagmtelits In Coll
fluelol. .4. loil. livelohnV, L It. ;FI!!!rt1jEl..A. 1. Khman'"'
an-I V, A Itt"itina (Ist A11111%
Allud, 'Valik S'S.V.R. 70, W- loll( 19151 ). --The tit
folol X..htxme;;mInr '14. *nil their 1`0110 Ili 111mirt, And cell
ntwlri in hiumn liver, hman spleen, cox liver, call thymM,
tand rat ~mrcotoma ishowett thAt
1111MOPrOtTfilil Aft tOMipancliti 0( Coll nuclei. . Ill$ stiftn. or
Me (Wookm of honnotopirsitilinis corstf, onomismofialim bdoWtv 0%
.."04 t-mvil-wo, eannot IW 111441" as Yet. The 11111fiell 1.0114,
tit N tit uilml N was found lit lite mit,411"A
~ptvinmrn_ timuraly. the nuclei train liver Asim it ratio tit
brxuw;xns.Lie N to total X that I% lower ill-tit In entire fitilue.
in nucki the rstio is About OAMS-011MI; in %Wscotim it is

cheskiy redaktor.
(~LaboratoO manu*al- of bloohomistry] Praktikam po biologichaskoi
khimii'. 2-a izd-.. ispr. I dop. Moskva, Goo. izd-vo mad. lit-ry,
1954..347 P. [Microtilm) (ICM 7:11)
(Biochatiletry-taboratory manuals)

t

9FAI Pro W- WRWMWM~1~
ZBARSKIT, I.R.; BRISHM, N.A.
Comparative activity of.adenosintriphosphatase In aqueous
extracts of organs of normal animals and animals witb neo-
plasm3.,Vop.onk.1 no.2:8-10 455. (KLRA 8:10)
1. Iz biokbimichaskoy laboratorii (zav.dots. I.B.Zbarokly)
Gosudarstvannogo, (onkologicheakogo G-sTffuTa-1-m-.7-.W. Me"e79--
(i.o.dir. kand.med.nauk V.V.Gorodilova)
(PHO'SPHATASES,
ATPase in organs of normal & cancerous animals)
(NEDPLASMS, experimental
ATPase in organs of normal & cancerous animals)
w:
-OMIMMUM M&A '"M k

-Iiiim4 ih, 6 ac to pracias or whole
f
tissue, cell- nudei and nuclear fric 0 0 orpedmcnw
tamars:aa4 no-mvel organs. I I,. ~! kir and K .0,
DaHady Ak-~' Va~k

iL 'Irgiidy ciriow that iiMtrfIV9
'V
.1-k ti,~u .Ql,~ an'[ 5PIL~_u ,f 1u
11J."t 'na fi~;muimil) th, OutAti fw.!"s .
uc! -41- UnLI, J-A~la
dw r-'Ic tit mmioLd 4 .1COL. "ZiO reblo,t)
i, -J.,44v In if.- !v"'r O'll(p m -A
i""
it licit v du,
ifI i

USSR/General Problems of Pathology - Tumors. Metabolism. U-3
Aw dour Rof Zhur - Biol.., No 16, 1958, 75444
Author Zbarskiy, I.B.
Inst
Title Biochemical Aspects of Study of the Carcinoma Problera.
Orig Pub V. sbe: Vopr. klinich. t eksperim. onkologii. vyp. 2,
Stalingrad,.1957, 96-113.
Abstract No abstract.
Card 1/1
7
777AC7144~4
omm T

USSR/General Problems of Patholo_!7 Tumors. Metabolism. U.
Abe Jour Rof Diur Diol., No 19, 1956, 09574
Author Zbarskiy, I.D. , Ferevoehchnilv)va, K.A.
Title On the Participation of Some Coll Com, onents in Protein
Synthesis in Hec)plasms and Worml Or~pns, fron Data Ob-
tained.by Liclusion of Radiuactiva Amino Acids.
OriG Pub Tr. Vscs. KDnferentsii po med. radiDl. Eksperim. ried.
radiol. M., MedC;is, 1957, 222-e24.
Abstract I-To abstract.
Card 1/1
19

-OARSKIY. I.B.; GBORGUIV, G.F.
"Nucleic scide and their. biolQgtcal rolem by O.P.Obeptnogs. Reviewed
by I.B92berskii-, R, Ge. . VopsaisdAhim 3 no 2:150-152 Mr-Ap 15?.
orglev, 0 a
(WGLEIG A 3 (OHNINOGA, O.P.) (MLRA 10:7)

AUTHOR ITIMMACHIKOVA, K.A., MAIMMY, I.B. -"~V64
TITLE'- On the Stimulation of 11-b-u-m-IF Sub-stances in uormal TiS3ues As YR;-0. As
in the Tissue of Tumors By YeanB of the Docomposition Products of Rl-
bonuclein Acid.
PERIODICAL
AMTRACT
Card 1/2
(Stinulirol anlye -klywhemLra ndwtmykh aminokislot v I-,91ki norma-&yk-h i o-
p4holevykh tkaney produktami raspada ribonukleinovcy kisloty - Russian)
Doklady Akademii Nauk SSSR, 1957, vol 114, Ur 1, PP 150 - 153 (U-S-S.R.)
The participation of nuclein acids in the biosynthesis of albumin substan-
ces wqs maintained by a great number of authors, convincing experimental
results were, however, achieved only of late (e.g.by E.F.GALE). There is,
however, hardly any sure knowledge on the activating influence of nuclein
~acids. It therefore was important to clear this problen as the participa-
tion of nuclein acids in the biosynthesis of albumin substances is of great
importanse (in connection with various physiologicalenel pathological proces-
ses). From the results achieved it must be concluded that the products of
the hydrolvais of yeast-ribonudWin acid considerably increase the radioa-.-
tivity of amino acids(An the albumin substance of normal tissue as well
as of the tissue of some tumors). A particularly clear effect can be obser-
ved in systems obtained in the case of disordered cell structure. Ribonuc-
lein-hydrolysate considerably stimulates the incluseion of amino-acids-
esp. glyzin 014 or metionAn S35 in cancer cells (VIRLICH) of mice- in the
same cells which were distroyed by ultrasound.
3 tables

On the Stimulation of Albumin Substances in Normal Tissues P-o-,,.-41/641
As Well As in the 71issue of Tumors By Means of the Decomposition Products
of Ribonuclein Acid.
'ASSOCIATION Not Given.
PRESENTED BY
SUBMITTED
AVAILABLE Library of Congress
~Card 2/2

CHMOV, V.A. (Moskva. G-131. Frunzenskaya nab.. d.sQln, kv..172);
SAIDOY. S.M. (Moskva. 2-y Botkinekiy.prMCI, M. kv. '204);
zuRsxiy. r.B. (Moskva, 1-51, TSvetnoy bultv. d-32., ky.36)
i~ro.tein_ changes in cell nuclei during growth and regression of
,transplanted rat sarcoma 145" under the influence of triethylone-
pho. sphoramide (with summaq in Anglish). Vop.onk. 3 no-3:283-288 '57.
(MLRA 10:8)
X...1z biokhimicheskoy laboratorii (Za - I.B.Zberskiy) Gosu-
darstvennogo onkologicheskogo institute im, P.A.Gorteena r. -
p;of._A.H.Novikov, nauchn, rukovod. - chlea-korreepondent A191 SSSR
p;rof. A-L.Pavitiskiy) I labor'a.torii'eksperimentalinoy khimioterapii
;)~Mk~q;ev (zav. - kand'biol.nauk V-A-Che2-nov) otdola khimioterapit
(Pav, --~ profo G*H-Fers~in) Vaesoyuznogo usuchno-iaaledovatellskogo
khimiko-farmateevticheakogo Instituta im, &Ordzhonikidze (dir, -
prof* H.V.)&bteov)
(GYTOTOXIC DRUGS, eff.
triothylene phosphoremide. protein changes in call muclei
during growth & regression induced in transplanted rat
sarcoma 45 (Rus))
(FRMINS, wtab.
changes In cell nuclei during growth & regression induced
by triethylene phoophoramido in transplanted rat sarcoma
45 (Rus)) -

prof.
and methods in the Zurther study of the bioebemistr7 of
cancer* op.onk. 3 no.6:753-761 157. (mm lia)
1. Iz bickhimichatikoy laboratorli (zave - prof. I.P.Zberskiy)
-,Gosudarstvennogo onkologichookogo institute im. F.A.Gertsena (dir.
prof. A.N.Movikov, nauchn. rukovod. - chlen-kory-espondent ANN SSSR-
prof. A.I*Savitakiy)
(NNOPIASMS& metabe
cancer tissue biochem., review)

S A7 r
AUTHOR:
Zbarakiy, Professor 30-8
-4/37
TITLE: 07n,the Problems of Cell B;*~ochemistry (Problemy biokhimii
kletki, Russian),
PERIODICAL: Vestnik Akademii Nauk S5311, 1957, Vol. 27, Nr 8, pp. 26-36
(USSR)
ABSTRACT: Today research on the most important biological phenomena
(growth and development, -rariability and heredity) are already
well developed. Explaining these mechanisms required a certain
connection between the mo-cphological and biochemical methods.
Biochemistry of the cells is thus located on one of the borderlines
between the sciences. One of the not unimportant difficulties
in cell biochemistry is caused by the scarcity of the research
material availablew The usual micromethodD of biochemistry are
by far not sufficient. The author next deals in detail with the
cell nucleus as one of the most important objects. He especially
points out that the properties and the composition of the cell
nuclei of various tissues (especially during the dtage'of
development) can differ considerably In-apite of an apparent
similarity. The latest research results show that the albumen
composition of the cellular nucleus is vary complicated. The
CEird 1/2 author then deals with the functional significance of the type3

--EXURP
1496.,0N THE PARTICIPATION OF NORMAL AND TUNIOUR CELL NUCLEI IN
PROTEIN SYNTitEsts MEASURED BY THE IN-VIVO INCORPORATION OF
LABELLED AMINO-ACIDS (Russian text) - Zb --4-U
A calwj - and Pere
voschikovi K. A. Biochem. Lab., State Oncol. Inst., Moscow - BIO-
KHIMHA 1957. 22/1-2 (295-304) Tables 5
There was'no marked Ifference in the incorporation rates of nuclei and whole
tissue proteins of rat and mouse liver, ap'leen and kidney and of the rat thymus.
Contrary to this the cell nuclei of transplanted tumours (rat sarcoma MI, mouse
Ehrlich. ascites carcinoma, and mouse C311A hepatoma) showed a much lower In-
corporation of the same amino-acid radioactivity than the whole tissue proteins
of,'these turnours. In the normal cell nuclei the highest rate of radioactivity In-
corporation was found in the 'acid proteina' fraction, the nucleoprotein and residu-
RI protein fractions being less active. In the tumour nuclei theacid protein fraction
was less active than the nucleoprptein fraction, while the residual protein showed
very little activity. Itjs suggested that cell nuclei and cytoplasmic particles play'
different roles in protein synthesis. The nuclei synthesize more specific proteins
needed for normal development and dilfterentiation. The impaired amino-acid in-
corporiktion intb the tumour nuclei protetris is regarded as a sign of nuclear damage
and of the Orotein synthesis alteration chitracteristic of dedifferentiation and ana-
_plasia..

MIM. M MeMMM 994 "atom
V.Y1
EXCERPTA -jMED-IC-A-S-ec--5--V-o--l-l-211-G-e-n----Pat-hol-ogy Jan 59
4. COMPOSITION OF DEOXYRIBOMICLEIC ACID IN SOME EXPERI-
ME'N'TAL TUNIOURS AND IN NOWMAL TISSUES (Russian text) -
1. B . Biochem. Lai). 'P. A.Hertzen' St. Inst. or Oncol., Moscow,
USSR - VOMMiIEM KHINIII 1058, -1/3 (199-203)'Tables 2
By means of paper chromatography the conte.11t of pu~inc and pyrimidine bases In
ireparations of DNA was studied in (1) rat sarcoma M1 (both from growing and
necrotic area), (2) Brown-Pearce rabbit turnoura, (3) liver and spleen of normal
1.1kis, (4) liplaell of WMOLIV-boaring rato, (5) liver and spleen of tuniour-bearing
rabbi* and (6) calf thynins. There were no differences between tumours and
normal tissues of aninials of the same species, nor between growing and necrotic
areUs of the same tumours. Slfght differences (not statistically significant) were
observed between animals of different specles,
(V, 2, 16)

Elm
ZBAIRSKIT, I.B. (Moskva, 1-51, 76vetnoy bullvar, d. 32, kv. 36).; uawavA, N
-MAIT&VA. L.P. .[deceaseC-1
Problem of the uplitting of putonen by blood nard of otinoer patie
Vop. orAc. 4 no.5'.561-562 158. (MIRA 12-1)
0
1 1z Gonudarstvannogo onkoloivi heiskogo Instituta im. PeA, Gertse
(dir. - prof. A.N. NovIkov, nituohn. rukovod. - chl.-korr. AMI SSSR,
Prof. A.I. Savitakly).
03MOSAS,
splitt.Ing by blo,)d of cancer patients (Bus))
03MIASM, blood in# '
pentose splitting by blood of cancer patients (Ible))

S=ITSKIY.A-V.,,otv.rr' ".d. -_ORIGOIVYXY,V.A.* red.
LIOZXXR~L.D. red-
red,-- 4. a.,, red.
T, t
red4-; CIONMOV,Yu.S., red.;. rod.* LATRWIWi#G-#
tekhn.re'd.
[Transactions of the Second, Histological Conference, plastic and
restorative proIceases] kastu;lieskle iyonstanovitelInye protses-
sy; trudk Ttont gistologichatkoi konforentaii, Moskva, Kosk.
nauohn.Qba-vo anatomov.,gistologov keribriologov, 1959. 319 p.
(MIRA 14-5)
lexafedrwgistologii Hookovskogo gosuderstvannogo universitsta
im.N.T.Lomonoeova,-Koskwa (for' Stiidltskiy). 2. Laboratorlys radio-
bioldgii. Instituta morfologii'zhivotnykh Im.A.K.Savertneva All SSSR.
Mc;5kva* (for'Gr ayevskiy, Zbarsl:iy), 3. _Kafedra estologii. I. s6brio-
logil laninVadakpgoisoniternt~.-gigiyenicheskogo neditsinskogo,in-
Leningrad (for' Grigol.ilyev). 4.,refedra gistologii i emb-
riologii 1-go Maditainskogo ilistittit6~ini.Sechanove.,H,oskva (for
Yellseyev)., 5~,'Gruppa biokhimii klatochnykh struktur Institute mor-
f ologii zhivotnykb, im.A.N.Bevo.rt sova- AN SSSR, Moskva (for Zbairskiy).
6. Laborstoriya r4s.ta i razvitiya Instituta eksperimsntallnoy bic
AHN SSSR, Moskva (for L!Lozner). 7. WentralInaya nauchno-
Issledovatellskaya Leboratbrktra 2-go Koskovskogo meditsinskogo in-
stituto im.N.I.Pi ogove Moslocrat (for Khrushchov).

DAVYDOVSKIY, I.Y., prof. (Kosixa), otv.red.; 13LOKHIN, H.H.i profi
(Moskva), red.; VASILIYEV, Yu.M., kaud.med.nauk. red.;
u"Aiall"AA. prof. (Kook-,m)i red.; *ZILIBM, T#.A,# prof,
Wskva), red.; KOSTAKOV, P.11., prof.,- rod.; LARIONOV, L.F.j
prof. (Moskva), red.; SAVITM:IY, A.I., prof. (Koskva)o red.;
SAKRMOVp A.I,,# profoo red.; CHAKLIN. A.V.. kand.med.nauk
(Leningrad), roda,; SKIjW, LUMal profo (Loningrad), reds;
AVIMBAM, H.H.g red.; ROMANOVA, Z,A,l teklmored,
(Malignant neoplasmat trincaotions of the Tenth Sonnion of the
General Assembly of the Acadomy of Medical Sciences of the U.S.S.R.]
-"Zlokachestvannyo novoobrazovaniia; trudy X sessii obshchego sobra-
niia Akademii meditBinakikh nauk SSSR. Otvet.red. I.V.Davydovskii.
Red.kollegiia: N.N.Blokhin i dr. Moskva, Gos.izd-vo med.lit-ry.
262, p. (MIRA 14:1)
1. Akedemiya meditsinskikh nauk ISSSRI Moscow. 10. seasila,
Moscow. 1956. 2. Deystvitel"Inyye chleny MI SBSR (for Davydovskiy.
Zillber, Serebrov), 3. Chleny-korrespondenty ANN SSSR (for Blokhin,
larionov, Savitskiy, Shabad).,
(CANCHR)

NO im
,.,__ZBARSrIX,-Lp*# RAMOSEATA, GeP.; MULIMAN. L*S*; TAMLA.YET, L.P*
Concentration and nucleotide composition of nuelate acids In the
ontogany of the silkworm Bombyx vori.,Zhur.ob.blol. 20 Dl.61428-
438 N-D 1590 (MIRA 13:4)
1. Institut Morfologii zhivotufth im. A N. Severteova AN MR.
(SILKWRMS) (SUGIC ACIDS)

ZBARSKIY, I.B.; GEORGIYBV, G.P.
Recent data on the fractionation cell nuc-%,ei of the rat liver and
chemical composition of nuclearstructures. Biokhimiia 24 no.2:
192-199 Mr-Ap '59. (KM 12:7)
1. Instit'ate of Animal Morphology, Acadeny of Sciences of the U,S.S*R.,
Moscow.
(LIVBR, anat. & histol.
cell nuclei, fractionation & structure (Rae))
LL NUCLEUS,
liver. fractionation & structure (Fac))

ZRAR IT, I.B.; rA IRA, N.P
Affeet,of.ribonacleic acid apd its bydrolyeates on the incluBloa
of glycine-I labeled vith C14 ITI PrOtOinS of normal.and tumor
tiesues..Biul.eksp.~iol.i med. 48.no.11r65-69 N 159.
(KMA 1-3:5)
1. Is blokhimichoskoy laboratoru (zav. - profs I,B, Zbaraidy)
Gosudaretvannogo oukologicheekoj~,o institute, twoul F.A* Gertsene.
(dir, - profs A*N# Novikov)-p Moskva. Predetavlena derstvitel'10-M
chlenom ANK SSSR A.Te. Braunshtoynom.
(GLYCINM metab.)
(PROTEINS metab.)
(UOPrASKS infitab.
(RIDONUCIRIC ACID 3.3harmacol.)

ZBARSKIY, I. B., SAMARTINA, 1. 0.) RAFEN'SKiY--A,--G-.P.
"Research on the Cytochemistr7 of the Biosynthesis of Protein in
the Silk-&-creting Gland of the ItIlberry- Silkworm."
report.oubmitted for the First Conference on the problems of Cyto and
Itistooliekietry, Moncowp 19-21 Doo. 1960.
Group of the BiochemiBtry of cenular Structiwes of the Institute of the Morphology
of Animals Theni A. K.Severtsov., Academy of Sciences USSR# Moscow.

13
V 'I
.1
51
;1111 ;,, -
UY3
APR
J1

v--ZBARS&11*-jjjB.; GECRGIYEVg We
Kethod for extraction from thiz; unfixed sections in studying the
histochemistry of cellular stmatures, To-itologia 2 no,1:95-96
Ja-F 160. (MIRA 13:5"
1. Gruppa biolchimii kletochrWkh struktur Instituta morfologii
zhivotnykh AN SSSR9 Moskva#
(EXTRACTION (CHEMISTRY)) (TISSUE EXTRACTIONS)

MIA
ZBARSKIT, I.B.; FMMVOSHCHIKDTA. K.A.
S~rnthesis of protein in Isolated call nuclei of normal tissuas
and in experimental tumore..Vop.cea.khim. 6 no.-1:34-40 Ja-7
16o. (MIRA 130)
1. Blochi.mical Zaboratory of the P.A. Hortzen State Inatitute o'!
Oaoologyg Moucowe
(PRMAIN. metab.)
(CM NUCL11)
(TuMaRS)

----------
.GBORGIYEV, G.P.; YEPNOLAIII-VA, L.P.; ZBARSKIY, I.B.
Quantitative interrelationship between protein and nucleoprotein
fractions in call nuclei of various tissues, BioWdmila 25 no.2:
318,322 Mx-Ap 160. (la-RA 14: 5)
1. Institut morfologii zhivotnykh.im. A.N.Severtsova Akademii nauk
SSSR, Moskva.
(PROTEINS INTHE BODY), (CELL 14UCLEI)

RAWSKATAs G.Po; MRSKIT, 1,B.; HILIVAN, L.B.
Nmalaic acids in silk-secreting ilands of the vilkworm Boubyz
morl, Dokl,&AX BSSR 132 no*3:!Y,06.w22G9 Je 160.
(XIU 13 6)
1. -Institut morfologii shivotryll im. A.N. Severtsova, Aka4exii
nauk BSSR. Predstavleno akademi).mn A. I. OpariVa.
17 (SITSVORMS) (AUGLIXG ACIDS) ("AIMS) -

ASTATJROV, B.L.; BEDNTAKOVA, T.A.; GIYj?SVURG, GO-J.; ZBARSKIY, I.B.
RAMHOKAYA G. P,
Eiperiments in the production of.heritable transformations in
the silkworm Bombyx mori L. by interlinear injection of
desoxyribonucleic acid. Dolcl.jx SSSIL 134 no.2:449-452 S
16o. (MIRA 13;9)
1. Inatitut morfologii zhivotiV,kh,im. A.H. Severtsova Akademli
nauk SSSR. 2.-Ghlen-korrespondtent AN SSSR (for Astaurov).
WeIsoxyribonucleic acid)
(silkworms)
:(Variatiou (Bioloj7))

ZaARSKIY, Boris Illichq profe(deceasedh ZWSKIv., Illya Borisovich;
SOMTSEV.416kcandr Ivanovich; MR;Vt re 7.;
W.A,,., tekhn. red.
[laboratory work in biochemistry) Praktikum po biologicheskoi
khimii, ~,Azd., ispr. i, dop. Moskva, 14edgiz, 1962, 279 p.
(HIRA 15:7)
I. Kafedra b1ologicheskoy khimii Pervogo bloskovskogo meditein~,
skogo instituta (for ZbarskiyjB.T., Zbarskly, I.B., So3ntsev).
(Biochemistry~--Laboratory manuals)

:ZBARSKIYj I.B.; GEORGIYEV, G.P.
Structure of the cell nucleus; ccmparison of-cytochemical and
electron microacopic data. T~itolofflia 4 no.61605-616 N-D'62
1. Laboratoriya, biokbimii kletochnykh struktur Instituta morfo-
logii zhivotnykh ANSSSRp Moskva.

7- -

lXjy -' A ,
DMITRIYFVI,, N.P.; MNOUY'
Z4b 1)%, .,v
Characterlia' 'co of the- riuclear, atruAurv of tumor.enl1a.
TSitologlia 5 no-54499-506 S-() 63. (MIRA .17:4)
1. Laboratoriya blokhimii kleti)chnyllch strWktur i Laboritorlya
taitologli Instituta morfologii zhivotnykh ION SSSR, Moskva.

ZHDANOV, V.M.; I.B.;, BUKMISKkYA, A.G.; RAIMISKAYA., G.p.
Study of-the initial stage of Interaoilon of Omdai viru-b vith
CellB ILM7, cr the. a3~toradiographjc method. Bul. eksp. b-lol, i. med.
56 no.7t67-72 Jlt 63 (KM 1723)
1. Iz laboratorii fiziologii vIrusor zav. deystvitelln7y
chlen AMU SSSR V.M. Zhdanov) Instituta virusologii imeni D.T,
I-vanovskogo (dir. - deyotviteltnyy chlen AM SSSR Y.M. Zhdancr)
AIV SSSR.i laboratorii biokhimii kletoohnykh struktur (Mav. -
doktor biologicheakikh nauk LB. Zbarok:Ly) Instituta morfologii
zhivotnylch imeni Severtsova. (dir, - chlen-korrespondent AN SSM
prof6 G.K. Khrushcher) AN SME, Moskvao

TSAIIEV, R.G.; W'MQV, G.G., '11W-M, V.S., Prof.. red.;,ZPA*SK-ff,
prof., red.
[Biochomistry of coll divAnIon* Tramlatod frQm the
Bulgarian] Biokhlmiia kletochnogo deloniia. Moskva., Me-
ditsina, 1964. 118 p. (14111k 17:8)

SMIRNOV, V.N.; SPIRIN, A.S.; KULLYYEV, P.; *.UISKIY, I.B.
RNA synthesis in the 6ilk gland of.the mulberry oilkwom. Dokl.
AN SSSR 155 uo. 4:957-960 Ap 1641, (H IRA 17: 5)
1, Inartitut biokhimii ira. A, N. R%kha "Vi SSSR i Institut
morPologii zhivotnykh im. A.-.% ra AN SSSR. Predstavleno
:a)m,,demikom, A.H.Beloieriskim.

GAUM, G.G.; LOSIWAREVA, N.P.;.ZBAR3VIY, I.B.1 GAUZE, G.F.
Composition of DNA in some ba,.-erla and their mutants carrying
oxidation deficiency. Dokl, AN SMISR 157 no. 2:457-459 ii 164.
(MIRA l7s7)
1. Institut morfologii zhivotnykh imeni A.N.Severtsova AN SSSR
i Institut po izyskaniyu novykh antiblotikov AMN SSSR. Predstavleno
akademikom A.A.Imshenets'kim.

ALEKSANDROV, V.Ya., prof., BRODSM, V.Ya.- BRONSHTEYN, A.A.;
BRTYABMG,,Yo.M,; VAKHT.114, Yu.B..; VD-INIKOV, Ya.A.,-
CAYTSKHOXI, V,S.;GOP.OSIICIO-.'KO, Yu.L.; GULMEEV, V.A.),
ZHINK114,, L.N.; ZAVARZINI A.A.; ZALKIND, S.Ya,; ZBtWK-IY,,
KATSUELISON, Z.S., KCUISSARCHIK, Ya.Yu,; LEVIN., S.V.;
RARAKHOVA,- I.I,- MASHAPSM V.P.; MOSEVICH, T.N.; IIIKOLISKIY,
N.N.; PESHYOV, M.A,; POLENOV, A.A.; POLYANSKIY, Yu.I.;
ROZENTALI, D.L.; RUPYANTSEN', P.P.: TITOVA2 L.K.; FEDINI L.A.;
KHEYSIN, Ye.M.; CHERNOGRYADSKAYA, N.A., TROSHIN,.AjS,,,V otv~
red.,- MEYSELT, M.,N,, red.; MIKHAYLOV, V.P., red.; NEYFAKH,
S.A., red.;.PARIBOK, V.P.., red.; POLYANSKIY, Yu,I.; red.;
RAYKOV, I.B,, red.
[Manual on cytology in two volumes] Rukovodstvo Po taitologii v
dvukh tomakh. Moskvas Nauk-a., Vol.l. 1965. 571 P.
(MIRA 18:2)
1. Akademiya muk SSSR, Institut tsitologiic,

MIARSklYj I,D,; GA=j G.a.
Effe--b of aotinoiwo-Lq 1) on the ln,~orpoPali= of labaled amim-i
acido into 'the nu."Idol ptobolrv-3 ot Plhelldh actites oaroin,%vai
Vops fneda khims 10 Tic a4!4Jo:-,-,U,7 j-149 164, (rIIIIA
_klet-ocliny1ch struktur inst,14.'itu morrolcgf-
laboratorlya blokbihil
otxiy~l lViontA SSFIR,

KULLYYEV, P.; ZBARSKIY I BI; MNSKAYA, G,P.; SAMARINA, O.P.
Biosynthesis of ribonucleic acid in the silk gland of the silkworm.
Biokhimita 29 no.31470-476 V~-Jo 164. (14TRA 18-,4)
1. Institut morfologit zhivotnykh imeni Severtsova AN SSSR, Moskva.

Yucl.a~c a-Ads in 1, ir` fc,
8 I-Ag 62.
,er colls. Vop. mode
'-RA 17: 11)
il-itut. in:xfoloct-'A 3 Severtsava
Tyi, zhtvot-ny~,h I (n,. nj A.N,
vm
AN o,- 1.9 tt A

ZBARSMO M.I.
Naturaiij baked rocka of Central Asia as a h7draulic additive
for the production of cement.. Biul. nauch.-tekh. inform. VIM
no.2tl5-17 163. (RMA l8s2)
1. Sredneaziatakiy nauchno-:ssledavatel'skiy insluitut geologii. i.
minerallnogo syrtya, Tashkent.

ZBARSKIY, M.I.; RAKHIMBAYEV, Sh.M.; SIW.VCHINSKIY, A.I.
Fused rocks in the Fan-Yagnob deposit as an active mineral admixture
to binding materia2s. Dokl. M; Tadzh. SSR. 6 no.4:23-27 163.
(WRA 17:4)
1. Institut khimii AN Tadzhikskoy SSR i Sredneaziatskiy nauchno-
tasledovatellskiy institut, geologii i mtinerallnogo sy-rtya.
Predstavleno akademikom AN Tadzhikskoy SSR.

YEM-11011, A.11., glav. red.; BACIMIN, A.V., red.; VOLODAIISKIYj LJ1,p
red.; GEISYM, G, S.R., red.; GIEZBLI;'Z,, _'~.Z.f red.; DUN-11UKOV,
G.F.f red.; KIMZ11p D.IE'.p Itd.; KLIKFIX0, K.I.v red.;
ROLIKOVf A,14,1 red.1 MiYLOV, PJ1.0
KORAJOVI F.V., red.; K01.
bred.; -LIVAITSKAYA, F.V..,, red.3 LOKS11111, E.Yu.,, red.;
015TAVITYAllov, K.V., red.; FOSVYANSKIYP SOS., red.;
PRUDEE'SKIY, G.A.) red.; RAZUMOV N.A.', red.; HI]MYANTM,A.F.,
red.; TATtra, SOX.,, red.; swiaiLL,TEIII, L.Ya., red.; BAZAROVA,
G.V... starshiy nauclmyy red.) kand. ekon. nauk; KISELIMM ,
S.M.p starshiy naucbrqy red.; GLAGOIEV, V.S., nauchmyy red.;
TUI-W-IOVA, N.L.., nauchnyy red.; BIAGODARSKMA, Ye.V.., mlad.
red.; SHUSTROVA, V.M., m1adshiyy red.; GAYDUKOV, Yu.A., knnd.
okon, naw%p red#; ZDARSKIY 'M.1. red.- LOZOVOY, Ya.D., red.;
iRal
SHICEYEV, A V _f FXr8,'L.M.q kand. toldin. nauk,
. 0 do o
red.; IZUBOVICH, Yu.0.2 kand. ekon. nauk, red.; SYSOYEV, P.V.,
red.; KOSTIj S.D., tekhn. rol,
(Economic encyclopedia; industry and construction],7koromiche-
,skaia ent:;:Uclopedila; promynhlennostt i stroltellstvo.
Chleny red. konegii: A.V.Bachurin i dr. Mosk-vap Gos.nauchn.
izd-vo I'Sovetskaia entsiklopediia." Vol.l. A - 1-1. 1962.
951 p. (MIRA 15:10)
(Russia--Industriea--Dictioriaries)
(Construction industry-Dictionaries)

;ZMSXIYI N.A., kand. tekhn. nauk, red.; KWZIIINA, Ye.B., inzh.,red.
[Tecbnical Innovations in Leningrad bakeries; survey] Tekh,
nichookie unoverahenstvovaniie; na Laningradskikh khleboza-
vodakh; obzor. Leningrad, Levingr. Dom naucluio-tekhn ro-
pagandy, 1961. 58 P. (MIRA 17:55