SCIENTIFIC ABSTRACT NIKITOV, A.I. - NIKITSKIY, N.P.

• Document Type: CREST
• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R001137030001-5
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: July 19, 2001
• Sequence Number: 1
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

I'I'
, , SOV/124-57-9-10348
On the Formation of Whirlpools in Front of Water Gates id Canals
the whirlpools. In the investigations conducted the intensity of a whirlpool formation
is characterized by the degree of the transporting c Apacity of the whirlpool, namely,
the number of uniform objects passing through the whirlpool in a specific period of
time. According to the test results, an increase in the intensity of the whirlpool
formation results in a decrease both of the velocity coefficient (~ and of the dis-
charge capacity of the gate aperture. As a result of the elimination of whirlpools
by means of baffles re venting back currents at the gate the coefficient o can be
increased by 1.5 - 3~o. The formation of whirlpools occurs in both unsubmerged
and submerged outflows. The authors also repeated the tests made by V S.
Fokeyev (Gidrotekhn. str-vo, 1951, Nr 5; Gidrotekhn. i melioratsiya, 1951, Nr 12).
The eddy-stimulator water gate recommended by him has contributed toward an
increase in the intensity of the whirlpools. A paper by S.M. Isaakyan (RZhMekh,
1957, abstract 533) is devoted to a question similar to that under review.
N. A. PrLtvits
Card 212

37BJECT USSR / PHYSICS C'~'RD 1 / 2 PA - 1202
AUTHOR NIKITOV, A.I.
TITLE On, the ChWi_ee Distribution of th~_- MesoriL cr,
jiscleon-Antinucleon Annihilation.
PER:QDICkL Zurn. eksp. i teor. fis, 30, 1149-11'50 (1956)
P-abi .6 956 reviewed 8 / 1956
S.Z.BELENIKIJ and I.L.ROZENTALI (Zurn,eksp.i teor.fis, 50, ~95 (1q')6,)' in-
vestigated the production of stars on the occasion of the annihilation of
antinucleons and computed the probability of the processes with different
plurality according to the statistical theory of the plural production of
particles. Here the charge distribution computed on the basis of the con-
servation of isotopic spin is given. Denotations: p - proton, n - neutron,
~ - antiprotor., n- - antineutron. The products of annihilation (pions) are
characterized by the signs of their charges.
The charge distribution for p-n is obtained from the distributi n for ph
(misprint in the original text?) by reversing the signs of the meson
charges. A table shows the distribution of the process with given plurality
among the charge states. If, e.g. the cross section of the annihilation of
pp with production of two mesons has the value a 29 than it may be seen from
this table that 0,167 of the cross section is due to the process

W~IT(,';\/ ~N I
SUBJECT USSR / PHYSICS CARD I / 2 PA - 1740
AUTHOR YAKSIMENKO,V.M., RIKITOVA.I.
TITLE The Multijle Production of Particles on the Occasion of
Nucleon-Nucleon Collisions at 5,3 BeV.
PERIODICAL Zurn.eksp.i teor.fis,31,fasc-4, 727-729 (1956)
Issued: 1 / 1957
The authors theoretically computed the distribution of nucleon-nucleon
collisions at 5,3 BeV over the number of secondary particles. These compu-
tations were carried out in accordan,~e with the statistical theory of the
multiple production of particles with and without consideration of~sobaric
states. For these computations the method suggested by V.M. MAKSIMENKO,
I.L. ROSENTALI, Zurn.eksp.i teor.fis (in print) was used, which makes the
exact computation of statistical weights possible.
The statistical weight of the various processes (in %) are shown in form of
a table. Two further tables illustrate the further distribution of p - p
and n - p - collisions obtained from the postulate for the conservation of
isotopic spin. On thfi occasion of a p - p - collision the process N11 2n
(its statistical weight is given by the table) thus leads to the charge
state (pp+-) with the probability 0,300, and to the charge state (ppoo)
with the probability 0,100, etc.
From the aforementioned data it is easy to obtain the distribution of non-
elastic collisions over the number of charged particles (rays) which, on the
OT znO Academy of Science in
the USSR.

NrKITOVA, A.U., Dotsent
Reparative and regenerative processes in focal and fibro-focal
pulmr-Ar7 tuberculosis. Probl.tub. no.2:39-46 Mr-Ap 155.(MLRL 8:6)
1. Tz kafedry patologichaskoy anatcritt. (zav. -prof. P.P.Brofeyev)
Ivanovskogo meditainskogo instituta.
(TUBERCULOSIS. PULMOMARY, pYqsiolo#7,
regen. procsonee in fibrous & focal forms)

BLAGOVESHUMSKIY, M.A.. Drof. Ovanovo. 2-ya Plakhanova ul.. d.10)
..NMTOVA, A.Ne, dots.
Epifascial progressive gangrene. Test.khir. 81 no.100.132-136 0 '58
(MIRA 11:11)
1. Is fakul 'tetakoy Idiirurgicheekay kliniki (zav. - prof. H.A.
Blagoveshchenalkiy) i kafedry patologicheakoy anntomli (zav. - prof
P.P. Yerofeyev) I-vanovgkogo meditianskogo inatituta.
(FACE. ulcer
phagedente (Rua))

NIMITCFVA, A. N. Doe Mad Soi -- "Pathomorphology of the developveut and self -healing
of pulmonary tuberculosis." Kos, 1960 (Acad Mad Sci USSR). (KL, 1-61, 205)
-348-

NIKITOVA, A.N.0 dotsent
Reparative processes In the lungs in TTinax-j tutercalnelp in
children treated with antibacterial preparations. Pediatriia
no.12:3-8 161. (MIRA 15:1)
1. Iz kafedry patologichesko-y anatam-1A (zav. - prof. P.P. Yero-
feyev) Ivanovskogo meditsinskogo instituta (dir. - dotsent
Ya.M. Romanov).
(TUMCULOSIS) (STREPTOMYCIN) (CIMTOTHMAPY)

I,I/I.
NIKITSIV. P.
... 1.
Rural medical station. Rab. i sial. 34 no.l!F3 Ja 158. (MIRL 11:1)
(FOGOST (MINSK PROT INCE) -KHDIC INE, RTM&L)

jA I
NIKITSIJFA. %-
-- aiwApow
XxPlolt. W - I 8W. 33 no.8:16-17 Ag 157. (MLIA 10:8)
(Vhito Rmesta-World War, 1939-1945--Ulmderground movements)

4
/IV I 1~ , *~ I ) i I I . i I I" -,
LTUBOSHYTS. I.L.. kand.takhn.nauk; NIXITSINA, L.M.. kand.takhn.nauk.
It4
Drying and heating corn in pneuratic gas dry9r3 before moving.
Vestel AN 13SSR. Ser. fiz.-takh. nav. no.2:137-143 157.(MM 11:1)
(0,orn (Maize)--Drying)

USSR/CuYtivated Plants - Fruits- Berries. it,
Abs Jour : Ref Zhur Biol., No 12, 1958, 53764
Author : Cholyadinovn, A.I., Ilikitskayn, K.I.
Title Biological Control of cie Developuent and Growth of
the Buds of Fruit and Berry Plants.
Orir, Pub Naukan i perolov, OPYt s. kh., 1957, No 7, 48-49
Abstract Studies of the morphological structure of the fruit burls
ard also of the degree of their differentiation before
winter quiescence and the subsequent development of
blossoms in sprinC were conducted at Moscow University
on the following: Siberain crabapple, Vladimir cll~erry
(Prunus cerasus austera), and black and Lmldcii currents.
The blossoms of the Vladimir cherry h---,e - before retir-
ing for the winter - fitlly formed outer coverinG orLpns
(calyx and corolla), a developed pistil, and only inci-
pient stamen protiberaices. The pollons, the st-nnen
Card 1/2

It,
j~ V t 11 1 i '. le", /-* 'I-/- 1~ 1/ 71.
GMTADIROVA, A., kand. biol. nauk; NIKITSDITA. -K.1,-'nauchnyy sotrudnik.
I,
ftologIcal Investigation of the growth and development of flover
buds of woody plants. Sanka i pared. op. v sellidioz. 18 no.2-47-
49 IP 158. NM 110)
1, Kookovddy gosudaretvennyy universItet in. K.T. loomonosova.
(Flower3) (Buds)

44-
VO
lhi3 W04 Often two~-X. Lawtxrmtt~~, and
oth- K'ails RitN4 to L~3 doo t,.y #mmmil t-wt.
a.-Id Orinnza,
lh~ Ai'~200-fl '~f mUing
of dynamiio fractzu-~ -A
Ow w3c pEaca dud cluti p aatvhc-a, kv~ reults a.~zu u~~hvdcwg
Tranaverm-a "a.
T-7-i - -----------
2
2f-

14M
soegimw --by 66
1 Ow = mout 0t V. if.
M. P, Humbsov, a, A. 1.
i IN
ffx Z-r
Voyachok and 1. 1. ShuJOR05PIT-riM
m6w!dtg1d"%I Not' z4VO4 Lab., lurid, 22
J4), 307-401~-Tht use Wa thormo-cm,f, mothod
or detutnining C In st"Is widir wnrks can-ditiomn
13 diammed.
TAV

AUTHORS: Ni and
--(Dzerzhinskiy Works).
TITLE: Longitudinal cracks on
(Prodollnye treshchiny
rellsov).
PERIODICAL: "Stall" (Steel), 1957,
~arpunin, A.M., Engineers. 368
flanges of railway rails.
na flantsakh zheleznodorozhnykh
No.4, pp.347-551 (U.S.S.R.)
ABSTRACT: An investiEotion of the causes of surface defects
an the base and head of rails in the form of cracks
and fissures stretched alon- the rolling direction,
usually associated with surface bubbles, was investigated.
It was found that the observed defects originate from
longitudinal cracks often present on the bottom part
of the ingots of rail steei. Tile appearance of the
above cracks on inC-ots was co-related with the fluidity
of steel and the rate of casting of ingots. With
bottom pouring the u-)timum temperature is limited to
a narrow temperature ran6e 1470-14'15, taerefore, the
real solution for the proolem is top pourinE_ From top
poared ingots the yield of' tfte -quality rails increases
to 90-92W. There are two tables, 9 fiLures and 2
Russian references.

~yv

T)=N) N.A., kand.tekbn.nauk; NIKITSKAYA, V.A., inzh.; BURKWI, G.N., inzh.
Efforts to avoid disca:rds in rolled telegraph vire rods. Stal 1
23. no. 5: 448-451 My '61. (MI -'-4A 14: 5)
1. Dneprodzerphinskly metallurgicheskiy,2~avod-vtuz i zavod im.
I
Dzerzhinskogo
jRol-ling (Metalwork)-Quality control)
(Telegraph wire)

TYLKIN, M. A., kand. tekhn. nauk; GREBENIK, V. M., kand. takhn. nauk;
KUGHEFOMOJP T. F.1 inzh,; ALPEYEV, V. G~, inzh.;
NIETSKAYA, V. A., inzh.
Heat treatment. of crane wheels. Maahinostroenia no-5-57-.60
S-0 762~ (MIRA 16-1)
1. Dneprodzerzhinakiy metallurgicheakiy zavod-v-tuz im. M. I~
Arsenicheva (for Tylkin, Greben1k, Kvcherenko). 2. Metallur-
gicheskiy zavad im. Dzerzhinakogo (for Alpeyev, Nikitskayff),
(Steel-Heat treatment)
(Cranes, derricks, etc.)

NUITSKAYA, V.
Research carried out at the Dzerzhinskii I%tallurgical PlOnt.
3tall 22 no.128107S*p 1086-1087,, 3.105P 11U D 162. (MIRA 15312)
(Ebeprod2orthinak-Meta3-lurgical research)

r- LIU9911AY&I I. -
Research at the Dzerzhinskii Metallurgical Plant. Stall
23 no.2:180 F 1-63. (MIRA 16:2)
(Dneprodzerzhinsk-Blast furnaqes)

. i-- - - --iv,
'!' " 4 , ~l " ": , , I -Zi - - , ,
,-, I - 7" ~; F, - , z,. " r. '" rr , . r. -, w a- C, r.- ~ X- I ;~ 71
~ i 3 f , , .. - - 1.

]LET V IT
Ch;nvinal Abst.
VIA- 48 No. 8
Ar,r. 25, 1954
rotrolewm, Lubricants,
A method of detSprifning the Of
mineral_gffl
1, and
Nejti, Ak . nu S.S.S.
slicaf streno, a,, cwnpuled from 0, Pdl I (where P, Is
" am,
oic cril, prcsmure at which motion of oil ocenri, d - 11
of apill3ry in cin , I - length of colu-nn of oil In c..) id
indep"dvit, within broad litnils. of rate of application a,
ario kuphalt load, diarn. of capillarY. and length of oil column
Pressur, accurately crTrrL5pondlug to the beginning of mo on
is taken as he crit. pre~sjirc. V. N. BeduarS, -in
Y

AUTHORS: Sanin, P. 1; Sher, V. V. and i4kits1c.aya, Ye. A.
TITLZ: Metal Dialkyl Dithiophosphates as o~mple~xAdA~Iyes to
Lubricating Oils. (Diallcilditiofosfaty metallov kak
komple'-3n77e prisadki k smazochnym Ma3laM).
I "ARIODIV'AL: Xhimiya i Tellchnolo iya Topliv i Masel, lo.Fjq, Nr.13-
pp. 24 - n2g. (D65-d5-
ABSTRACT- In early articles it via3 shown that met~,l dialkyl dithio-
phosphat9s are active complex additives (Ref.1 - 2).
Dial'cyl dithiophospha-tes of various metals have varying
effect on the detersive and corrosion properties of. oils.
j
Tests were carried out on t7.*io types of oil: the oil 'I"LS-2u
(Irom t~~e Emba Refrion) and the oil (from the
Baku Rerion). kroperties of these Oils are Fiven.
Prom Table 1 it- can be seen that these -,dditives 3how
varyin[~ de,,',-rea-5of activity- The most active adlitive wa s
the barium dial'cyl dithiophosphate DP-l --iheD adle to t he
oil ',,'3-20. This adlitive contained about 4~o Pp 9ij S, ~L nd
8,5f barium, and w-ts used in the form of a 50% solution in
spindle oil AD. T-ie action of this ad 11tive on the character-
Istics of wirlou3 oils was investir7ated under laborator7
conditi-)ns. Table 3: thecbpendence of the corrosion of
Card 1/2 oils on the concentration of DF-1. liesults of this

Metal Dialkyl DitAophosph-Lto2 ao- Aljitive3
Oils. I - to Lubricitlnr
investigation indicate that the Optimum con~-,ntration
of the additive 3:,'-l is about 3%. Other te:3ts concerriel
the effect of the additive on the oil V,3_20 aith repard
to its stabilit-r to oxidr-ition (GOST 4953-49), and its
tendency to lal-ou~r formation (903T 6049-51) (Table 4).
The acid number of t'~ie samples containinp the adiitive,
after testinr in the device PZV, .,iere _,on!jid,,,rably lower
than for oils not containing the additive 5).
Practical experiments were c-trried out on the one-cylinder
engine IT-9-3 (devisedby VNII NP)under the supeT-%rision of
V. F. Filippova. Results of these tests are j-iven in
Table 6. Table 7: the effect of the additive on the
solidification point of the oilsi Table 9: the effect of
complex additives on some properties of the oil LIS-20
(containinf- 3,"? of the additive). There are q T)~bies and
4 Soviet References.
ASSOCIATION: Inst-itut nefti AN SSSR. (Petroleum Institute )AS USSR).
Lubricant additives--Effectiveness 2. Phosphates--Applicatic.rs
Lubricat-ing oils--Test res~.ilts
Card 2/2

50). SM sw/62-59-a-15/42
ARM= 3 fttra.. Al. A.. Sarely.mk.. S. R.. TS.diliaa, A. L..
-So.h1tarla, S. A., S"Im. P. I.. EWS.I.Y., To. A.
TMA 2 mystb-la WW Properties of tb&
""AN "' Cu'"al"" C12-C16
PUMICAL. I ... tly. Akadail amak 333R. Oid.lonly. kht-i.b..kikh ... k.
M9. R. a. vp 1421-1424 (tMSR)
ASSMACT. Tb. pro.-$ P.Pr 4i.camaa. %a. "th-La -a pr.Y..ti.. of

memis at th. ^pound. ...tlouod Im tb. titl.. Tb.
.
at the MYSUM.04 aaa.rll. are give. L. ubl. 1. B..riy

I-
..a Ioa -1y 2,4-41
t 14 a" oad 3,5-4imotiql4odavans itrify at -h I...,
Umpam= 0" so th.ir L.-r. - h ... I.e..
SmaidG4 reference 3 Lu"ot1satime &talus at " explanation
of %h". phaboasua t- al.. bass a-I.d out by P.tr-
(&or 4), It o" 4 tb~ t the ahar ctorletic feature of
Lift"t tbo ;wo A 1. 4.. to that,

1
struatura. Tartaus in,rastisattons oar* oarri
1
4
-
-
tat. .* ... ption of 'i .... ity :
. n
-
:~
Lao
to. rmt~. (T.bl. 2) &a4 A. %.-I- t".. of
IshIr '.. th. ra..It. Is I. .. .. that th. influ .... . f
Cars 1/2 h. 2 th. ,ItrLfi..11- ff..% .-.t ba Ilalt.d.
.11
It .:. -1j, p-1bl. to ..t.blLb . -X.i. d.p..d. I
&b. rualh Inc 4.cra. of th. no,- -a 2
mad, ..via% W.-....
UTICA1 to.tit.t aef,~ , . , ,_~ , .
Tu.111t.t: !f tb. ".dw of a., ...... USSR)
SEMEMID; D....bor to, 1957
C-4

W58
Q
/000/01GIC12/0'a
5-l'.60 a la %. 11 S'N o'll-i 31/o,065YI160064
AOTBORS, Al. L & L
~d 3,~hit%41: --A:
?lTLX: l7atho:1. -4 P-P.-I-0 of
at." If o.
f %h C ..It C24
IMLIODICAL, 1. **ttya Lkademit cauk W. :._C%del&nky, khiwich-ikb
"T 1960. It. 10. pp. 7834 '85,
I:d-4 -;:'.I hrdralx.r~olo th"- 11 1 1
%.I. ton W _. .: .1: , th. hy4_-r boo.
betl I.W fractions. Th. P:P., '.P
byd-.rba.s Lth at. 4 _1.1 .1.1-4 24
an& prop-ti.. of 23 t
kylLrocurbou ates. Par W10-10. COMP&rad to a st.LlWr -'MtL4~tllb --/
find "t by It. ll'I,l 1".th. V~ ....%or. and.
as a larCtr as It ...... of %b.
- n Is If .7"
kiy4rocamboa %Lh- ff--t of th. rol:tive pomtion of on*
Sy.1.8 1. th. par.M. bl. of th. so,..."... -4 th. -fr-t of th.
on 1, 'y paro""
as a- to
(of 9.homs of h. 11~1:hllydra:-bl 1 11
r.
th.;J..4 by th.'Crl" th. V~
at ~:.4 ~..th~,l of
:par phom. by a.- f so al
.Tii-tp t_1... 1..t1 ~hj. . h*.,::dr*.d,,*
dl.tIll.t
Porif to J:a wan carrlw4 ont by to. 'd
tia'as of synthost. ara deacrtb*d In d.tail for -41ph,nt
'h it. .14 . h.'t 1. cl... .. th. prop-
22 bjd-"b-.,. 31- ::,1r1
dah" bon.7% was b..-4 -'.: tp:;ra. th
('j,jCr&rd th to, of ,. -t~- b.l....
shoyl halid.. and _:.&l:: ... dh(T.bl. I . do'. a 4, "1
t t'W.'
':. 1h .;art-%
a-so f.';'-' nod
T b1 2 - th
p-p:rti.. or th. 23 hyd-oarb... ;bialnod. Th- ahl"I- If
th P,
"r% fa~oc%ah afrvthe 1:.7:,* "r. . tt'. p..lY.-,yl
do toots arkbI Itlz ydm:nrb-o h-04
C-4 2/3
Oml C,..p. a. th. rt.9 h- a u*l, h~Cl.-M:t L%Y that thO
woca.betlt.t" Is th- --- , f.,.r.h.-r:o::l I P'b'lb
,Vapor as tho,p iGo-ab:slc&l pr th. I%Yl-..rb.a. 4-rtb.d
b.- (data to .,rjt .. .; %_) . Th:- .1 t.bl.. -1 13
5 vorl.1t. 3 US.I r- _-, and I ~Mtl.b.
MOCIATIOll: 1. ti%.% C..I*Cli I r%*r%bo!kL,c=.tlkb
J=ewll -k ISUI (lMtl%u.9 f2Aa ah,
.fvl..r.1 Pu.i. of th. A..do.y -332,
SOMIMM, Kay 6. 1959
C~d 513

SANIN. P.I.; PSTROT, AI.A.; SERGITMO. S.R.; MIXITSKATA, Te.A.
ViscouA properties of some C24 cyclic bydronmrbons. Zhur.prikl.
khim. 33 no.4:919-930 AP 060. (MIRA 13:9)
1. Inetitut nefteLchimicheskago vintexa AN SSSR i Iastitut geologit
i rasrabotki goryuchikh tskopayemVkh AN SSSR.
(Hydrocarbons) (Viscosity)

0 67 i70
AUTHORS: Sanin, P. 1. , Petrov, Al. A. , S21S,1Lyenko, S. it, , Academician
AS Turkm SSR, '~ ;:I~ Ye. A.
TITLE! Viscositylproperties of Alkyl-aromatic Hydrocarbons and
Their Hydrogenated Analogs
PERIODICAL: Doklady Akademii nauk SSSR, 1960, Vol 130, Nr 2, PP 338 - 340
(USSR)
ABSTRACT: An investigation of the viscosity of aromatic hydrocarbons
containing isolated benzene rings, and their hydrogenated
analogs, showed (Table 1) that the change in viscosity on
hydrogenation considerably depends on the structure of the
hydrocarbons. Hydrogenation of certain structures reduces
the viscosity extraordinarily. The aromatic Ixydrocarbons
(C ) investigated here may be divided into 2 groups:
24 0
without substituents on the ring (Table 1, lira 1-5); 2) with
methyl groups on the ring (Nrs Hydrogenation (or trana-
formation of aromatic into naphthene hydrocarbons, re3pecti-
Tely) of the hydrocarbons of the 1st group increases the
Card 1/3 viscosity, and causes a higher viscosity increase cith de-

Viscosity Properties of AlKyl -arumatic Hydroca:-b~ns and 50712C 50 2 -26/6 Q
Their Hydrogenated Analogs
The data obtained by the authors make it possible to asgert
that the viacc;sity on hjdrogeaation of the higher-biling
petroleum fractions may also be reduced by tne presence of
polycyclic arraiatic hydrocarbons with isclated benzene rings
containing alkyl- (methyl-) gruu~,.q on the r-inp, 'he cause
of the viscosity chanee of some tX~es of arumt~tic ny1rocarbcns
on hydrogeriation is unk;.jwn and must be investi~,ated yet
There are 2 tables and 4 references, 3 of a-re joviet
AS50CIATION; In5titut neftekhimicneskuggo siriteza Akademii nau,< S3~;R ~In-
stitute of Petro lewn - chem ical Jinthesis of the Acz.demy cf
Sciences, USSR) Institut goulopli i razrabutki goryuchikh
iskopayemykh Akademii nauk SS3R (Instit ute of Gecdlogy and
the Workin of the Academy ~f Sciences,
USSR) -_g_of Comb,;stible 1,11nerals
SUBMITTED: September 22, 1959
Card 3/3

SANIN., P.I.; BAGRIY, Ye.I.; PETROV, AI.A.; NIKITSKAYA, Ye.A.; TSEDILINA, A.L.
Viscosity of C~)z and C28 polycyclic hydroca-rbons. Neftek-A-iia 3
no.6:835-844 --~~D 163. (vIRA 17:3)
1. Institut ne-'tekhimicheskogo sinteza AN SSSH 4~7i. A.V.Topchiyeva
i Institut geologii i razrabotki goryuchikh !skopayemykh.,.

.1 . , ~-- . 3 .
" Sur '_,,i - l'--j~i.)i, : - I Iii -- : - . , 1 ': ~~ ! , ~ -~ -, I, ,, - . . 1 z
i ~ L., .~ - 4 - . I . .1. -
b, 3 . -1. Lo~--Ij~ c+-rli c~-,: ~~ . - . i'.-)v .--~ Z . -- . -~c . %! -X.-_- i
30: Jji-a-n-1 I o-:" -'encrnl .1": ,.1 '*-.-,-,,1-,. L -~ "', I' , I -) I ,
., , - I - - ~ I - - I

0 a 0 0
0
0
0
lb
40
0
6A

00

SYRON"At in am isminsco-mummi w4ws, 1. ia*- CA" (P-4cXII(*AIIs_"L7Iy)p, m Zl" (fresem AcfAI
!M
. .4t;
It dIAL11111YU1112111,31tillYi MUWAG. 1. Kh Fel 10 and JIcjLng; 21 g. p4IXCjI.SjJ ..1 41. KOJI in ISo all
( At
00 NtkjUk4y.t Zhilf. fAhAket Ahim. 1j. Cku. Clicni.) HOU to builim4g, .4ad AMn. Ill 13.3 g. 00
Redusting 45 nil. PCIA in 2W Mi. CAVC, ItItzir filtratkin, MIICII.. Aud thIn., Gli"s,
'CII,U), Will L04.5 9. I;tI%CII,CII,1)H In 13 tell. (CIIICI), VC11,01,N.Ifill, ml ill IIIC/ all fl, ni. '115 17' fr,.ti -00
00 At 6 lift. javr, After ckmn.. ill IQ). filtVAt"l, And F101I)I, MIU01011 With It Asul RAfirv :I All IA()II M
.00
ssittil. III At", N,011- ?V, hj,N0I,C)I,0- TIm d, We Issuill trulp- gavr 1.41" amisis, jr,jr Itult IJI-11(l all,
'
..4ah's .-ul."I . ...... Lot) u1 is" V. Ill A,141H.Ud 3 g. I- I:- ill 2TJ 4
Orwit Fit)IIII. Ili Q At ) 1113 ust AcOll -00
*0 Nk'IfA'IIA*l is- 4 -.4 At 4 A. 1,, :41 ,it I. timed with 2 1 uAl "W: 11,41), It -it And 114-AICII ~ 11111 At
* _411114111
00 75-*)
gave m. lipj 10

06 x 1 frusn FtOll); IIC7 sail. in. 14.49 201 '. This (2 #.1 And
' All 0
11S a. NlIsCl In Lo nil. 11,0 trratcd at 70
with 4A Al.
powifer and sitim-41 0 hirs. gave, Ulk"I exist. with NtcCO.
0.3 j. makosomin ishilance (11). Ili ll%b 71'. ssful,, Vill I
"
-%tn.pve411; In. H"
8%
s
also obtained sit 95'r yk-14i by tedurtkin with It
mut
Raney Ni. A similar sMencir J rc"tions. surting with 410
Ht,NClfCifCl, give IV.'
' -.00
00 An oil. who- 110 sail. tiv 172-4
. A;A%v 14', 4 the silly
J-Ali, amal". (di-110 ~dt, in IKM 00') 1.v 11 ir"Itt, l".., ~66
00 whil, 11.44 "sistill ... I :-" , 4-4),Xl.*sjI..1,s),( /1,4 11,
- .00
00 Nl-;f,, its. W 5' Ar ... As 1-101i1 tilt
/ .,Ill. its. 1.145 7, .
smshich by Fe redn,tian gavv wine a-Nil, analog. -I M ~00

: I(X)* and 34r;. 11. sit 171'. RAury Ni-li mthwim g- -00
2
40 !it)' r of tilt issurc ulfunc, in. 98 1(W U_ ul 1-1,\.
C iI)ICI IrAV In Will 7.71' ; lssl~ 4 B. N. ('11, 1. \ 1--il
7
'
//,
\
I -00
,
iali. in.
146 h 1. M
11, All sul ~111-ilk- i
%
. 4
*
' ~60
-It. 111. 101 3
l, 70', 44). N t
.Jl._%0,k t-4,. us. 57
11' t IICI tall, in. 191 :1',. Aud smah,g. us. 7.4 :60
ips 9, lfroul
so 1 -00
00 4

L3 l d"a
0 0 0 0 0 0

USSR/Chemistry - Pharmaceuticals Feb 52
"Synthesis of Aminosulfides and Aninosulfones. V13I.
Synthesis of Aminoaryl- Q-Ketonosulfones &M Their
Derivatives," 1. Kh. Fel'dman, Ye. S. Nikitskaya,
All-Union Sci Res Chem-Phar Inst imeni S. Ordzhon-
ikidze, Moscow
"Zhur Obshch Khim" Vol XXII, No 2. pp 278-285
Prepd 12 aminoaryl- ~-ketonosul-fones and derivs not
described in the literature. Studied acid proper-
ties of methylene group in 2 of these: p-acetylaul-
nophenylphenacylsulfone (I) and p-acetylaminophp" I
p'-acetylaminophenacylsulfone (II). Found that (af H_
atom of methylene group of I reacts with alkylha3ides
USSR/Chemistry - Pharmaceuticals (Contd) Feb 52
to form monoalkyl compds, with aldehydes to form
ethylene derivs, while H atom of methylene group of
11 under same conditions does not react vith alkyl-
halides, ~-.-.t reacts with aldehydes to yield ethyl-
ene derivs; (b) ethylene derivs of I and Il prepid
by reaction with salicylic aldehyde (III) react
v1th Br2, adding Br in nucleus of III to form di-
brosides; (c) hydrolysis of acetyl groups of ethyl-
ene derivs yields amino compds vhose double bonds
can not be hydrogenated at normal pressure and ro(m
temp or in presence of either Raney Ni or Pt (ac-
cording to Adams) catalysts.
2097!25
.7~
U3
E_

T" 1,
TA,
mZOTIC-~-
onthl--.- Lis t of cce-E - orls, -or.

--pv
W L, a ter- th, -1 twill-,WAIllip
-Pt.
iiitlt~- 'A IV* g.) (r"ica ewr-llcl .1 1"Y* 3.9 K__ 1. F (CI
~*;O, dts~,~ a--i - not
j,:,ttt -_,J~25 j-'j, X: N wed by &I (W, ab-i.
40if folln Ef(Iff
-it .---K
io- IT -Dft-r
mcff- With -XITISA
wjf~',
A. ~Prcl~ugul fill-fe of
f tile fijtr~jtt 61
Cue -:0.1.
fied tit I TeMcrl- with lo% tic! I gave tjiL (tit:
no
whi. U_
ll~
--the cxU~
Vi
r-A fort
Mit MR
, Tv:-,
quP
rkt -1 -.vvr ri,
V pW%SIjrC- g-47C 9 1
00

NIKITSKM, YE. S.
usm/chemistry - Drugs Sep 53
"Aminoalkyl Derivatives of Quinuclidine," M.V.
Rubtsov, Ye.S. Nikitskaya, Ye.Ye. Mikhlina, A.D.
Tanina, and V.Yi. Furshtatova, All-Union Sci-
Research Chemico-Pharmaceut Inat im Ordzhonikidze
Zhur Obshch Khim, Vol 23, No 9, PP 1555-1559
A number of substituted 2-aminomethyl quinuclidines
and 2-aminomethyl-3-( ?-aminoethyl)-quinuclidines
Vere synthesized.
268T33

4-Ito=yfpjtid,nt (13 [it PhMe with MTO
yields a Colorless solid raixt, of NuIMI, awl Nfu a-
(M; cry5tn. of the
ti rom 11:0 ykIds M-Irce n"Mes oi the inner jali of
2neftdh4tjf4IdfOMk agid, With tvallititill 61
So.,., Ai6H acts similarly. Ifeating U briefly Avit-h
~&M,imtri. with CHCh or EtO, and evapn. of the
Lavd aa,dla-rfferiaxliquid,-b. IW7*, which erystfilli!ws,
In thh-is pure 1; In ciontattivith a-r-it yicl& the Ay-
C, M, 68-W%~ Much I is d' istd. alnng with the s~olv,-.nt
yvej~ u can be deteded by addo, of ~AOIWIC4, Wbich-
fmraazant. yellow M. 216-17- (from MORI. UICI
h CH 60,H), In AcOH at 8-0~ clelo

NKITSKAYA, Ye. S.
6ft- , -
B&stc methods of Isonleottale acid production. Ked.prow. no.1:12-14
Ja--Nr '55. (Wj2A 0: 5)
1. Tessausn" nanchno-issledovatellskiy khtatko-farmatevetichaskiy
institut isiol $..Ordzhonikidze.
(NICOTIMIC ACM ISOPERS. preparation of)

Alkk
f7
:,,4
?A,~ 50M

42 In'Ucildiniviloroplonle- acid.
W.
Sy~Lbesfi of
,
on 0v, and "ga
iWsov L N If; -5. Nikits
,
Ift-M
T
Ei R
R 5ffr

tou
tem,
.
h
k
It 7
l Xhi
23
z
b
h
e
m.
i
e
uii
.
-ml.
ftkinii~g f6rmylqul~uclldlat, a
-
Ws piptridine with 0.8
g, C!14C~Vt), dA"
142-3'
1
4821
.
.
til?.
cd, HQ a hrs. it Jpxv
withcon t W%
,
--;
acid-Ho, in- 191-11" whiT_l1ydmgj"~tf'd ovei. 16n
--
add-)70-, dccomp~ 2L5-
I(se': al hydrMysis-of -the e5tor b
so forlaed.frou. Upon
'
140-50* ubtai~ed by.-corultaiatlau of
2-brvi~oeth-ylqmi-

lid -1113r_wIth MICH( Tri
ue ice COX _~3011,or nf: Ifte,
D
atfil 1ICI: halt- Nvidh SqCl;, Joiltiwed by TtflUXilig 010. Cmde -
.-,..Cyl Ailuride vvith Bcoff lj)pro
t. jit.37.5% yk d,

M~ F~*,!~n~,~-.---l rem m Y,--
mmusaum-M-M -9-0000--m-50 -W.
34 'i~~
L-A. --j

IL
oil

. . . . . . . . . . . .

=Z7 i7 - -----
7
aigh o, aitrit-
M"M

'
l
lh
or"I'alm, mnl-,
uf rrrjg~v t
~wd ~~F- '1 ;41- r~wduql ;.Aq ic, Iz w! g~~-

, i ff~v -J
Aq. -lu "y1p, _i". which ~:um L~
dirctly f~r cu'Lalkwo w wbiva C~-% 23
!
A,
-Fter ~.Pr. i's vazj, dm ri,~4dua vro-s at-aV4, twim, Witt-, As- 11
- 1~ 1, M e U
V~~tftd a! 1% , yfet"h-7.1 ~Z - haahy.

-
psridine, in. 934" ~Jlim) LIOU). vVd~ by, vmAmg ~tth
.
E
gae.sl,~61%f maftr~tefAy.,-
tj(~;
4
*
h
j
iJ
7~
J
,
ine, 1
Te the snixed mcthylol defivs
py?
y
'
96-10W the;-i was P-ddc-A in 2fj--
whi. 66 C~ 251".
ll,()~ and 64.9 g. ENO, aftel. subdifimce -' 0-1
~he -Nt- -6 L.'-(~j !, 11M. at 1(;0- If-j"
dtrr Cwting wma nvitnuilzat" !licrz wm "-~nvd
-aer
Lqniwji~ic uiA(L ~~,l GZu Aly
N5 flt:j
'alt, p'. 1, -wl-
lli~ 1.) R(Orl Gver liw
t
4~
,
.
j
-4-J)'; di
pa
Lit, wq~a~, whi"-
- -Im in t,,U~
;n. L3 il(A CCH.'
T,
,~iv-bm 1"loil n~a 1M g~-

USSR/Organic Chemistry Synthetic Organic Chemistry, E-2
Abst Journal: Referat Zhur - Kh1miya, No 19, 1956, 61543
Author: RubtBov, 14. V., Nikitskaya, Ye. S., Usovskaya, V. S.
Institution: None
Title: Alkamino Eaters of Some Heterocyclic Acids as Possible Hypotensive
Remedies
Original
Periodical: Zh. obahch. khimii, 1956, 26, No 11 130-134
Abstract: There have beer) synthesized the diethylaminoethyl asters of dipico-
linic (I), dipipecolinic (II), N-methyl dipipecolinic (111), 6-
methyl~picolinic (IV), 6-methyl pipecolinic (V), 1,6-cimethyl
pipecolinic (VI), and quinuclidine carb*lic-2 acid (VII). On
pharmacological investigation it was found that the di-methyl
iodides of VI and VII have high ganglion-blocking activity. A
mixture of ~"g dipicolinic acid (VITI) and 30 ml SOC1 is boiled
until compleifely dissolved (48 hours) heat the thus iormed di-acid
chloride (!X)' with 30 ml diethylaminoethanol (X) for 6 hours at
Card 1A

USSR/Organic Chemistry - Synthetic Organic Chemistry, E,0
I
Abst Journal: Referat Z+ - Ehimiya, No 19, 1956 , 01543
Abstract: 90~j BP 103-1050/0.25 mm, and the ethyl ester of 6-methyl
pipecolinic acid (XV), yield 92~, BP 99-1000/13 mm; hydrochloride
MP 213-2150. Mixture of 4.27 9 XIVI 1.32 g CH3J and 23 ml abso-
lute alcohol heated for 6 hours at 4c)-450, evaporated in vacuum,
residue extracted with dry C6H6, the insoluble hydroiod'4e of xIv
is filtered off and from the benzene extract is recovered the di-
etkyl ester of N-methyl dipipecolinic acid (XVI), yield 52.7%, BP
107-VO/0.2 mm. Analogously is prepared the etbyl ester of 1,6-
dimeThyl pipecolinic acid, yield 43.7%, BF 53-540/0.2 mm; hydro-
chloride MP 198-2000, Im 7 ml of X are dissolved 0.01 g Na, added
with stirring 1.32 g XVI, heated 3 hours at 1500 (distilling off
the alcohol) excess of X is distilled off, the residue is treated
with 5c~ soiution K2C03 and extracted with etW; III is thus ob-
tained, yield 51.2%, BP 176-1780/0.2 mmj methyl .iodide and hydro-
chloride are olly subs Analogously is synthesized VI
yield k4.-7,%, EiP io6-.lo8 0.25 mmj dimethyl iodide W 201-202
Card 3/3

7; Uri
4, -Am ta"y k;~,
1M 9.) Of ml. dry
tojl t -mum
........ .. . ..... .

1
7UPYTH 7j 1w
7r
.
-

"Ojovebim at SO. 120' tlic-,v ze-4 uy'lloun-
I
~a tion ~.,f I a t: i 4k Et tf4

It C

4"0, i)-i
an
med;

latol 4 1
n 41r,-:trr ~vc
r4
I WIN

A TJ f H 03 Nikit3kaya, Ye. S., R-;btsrv, ". V.
T IT LE' Synthesis of bicyclic SystQms 3,aztlir,,~ F.,,,,fr, 4,6-Lutitiine.
Synthesis of ~,l)-Nonines
(Azobicyclic
Sintez bitsiklich~~.-3-'.*Kh ijkYody, -4z :2,6-lutidina')
Siritez 9-Metil- 2- oiksi - ~-i - - nanana).
~
PERIODICAL: Zhurnal Ob!3hchey Khir.-,'i , 1~1.i7, Vo.. 27, Nz- 1 1,
pp. fl --,1l S (U.-~SR)
ABSTRACT: The inveslit_a,i~)n of the ~~zubic,clic t-;oi-pQun4,-9 of the octane
series (quinuclidine, tro~~--ne) t3no~vu,,, -,h~~t t,.-2,, ir, of f-reat
interest as raw ~rozuct!3fbr '~I~ s,!~'lneqis of ruiiiedi.Qs. I~Lus
compounds w th curativu,
mydriatic and other pru,,ertie,, ierf- liicover&ii ifonf Lile
tropine derivativ~3. It w..--t:3 of inti-rest to i:iv..--s- ~- ~,'e the
bicyclic sys,.em:3 close- to the tro-.an,-- series. T, --us the authors
synthesized 9-met:yl-2-oxy-9--az.-'-,ic"ClQ- ""''I )-norane
hy startine, from th~ ethyl cster of z.-Ll,-!th,-lpico',4nJlc acid
(obtained from 2,6-lutiAline). ',S,~e the -~roces2 of reaction).
2he initiil, inteime ii:~tu anr! ro-,iucts are as follows.
Card 1 /2 the etl,~l estH-r of th~! of

Sytitherlir) of Bicyclic Syo~(,.mp 3-trti.,.s~ Fr-,;n 7 - - 1 - - ' 4~ , / L" 9-
S.inthesis of 9-14ethy!-2-0x~--9- A zabicjclo e3 (A zcb I,,- i
its condensat.or. Kl,h -hicral, 2-c,-~rboxj-6- -carbox,,vinyl)-
pyridine, ,,,rbethox,~
9-rT,eth.!- 1-2-ke to-q-azobicyclo 1 w'ric!. :n rej,-~ction
with %lumin,,~mh-,dritt~ 1i--.1U:n- 1',
2-oxj-',4-azo*1.)icy-.1D ",lo'-nonane.
There are 3 relerences, 1 011, w...ic~l ~c S:"---v:C.
ASS~,CIATION:AU-Union Scientific P-esearch Institute for Pharmaceut-'cal Chemistry
imeni, ). Ordz-onikidze (Vsesoyuzri dy naucrino - is21e1'ov----te-L,swi.Y
khimiko - farmat3e v ticY~~.qkiy ins.i-,,at im. S. Grdzhor.'kirize).
SUBMI"TED: Nove:ber 27. !?,6
-1VAILA-K-: Library of Con,r,~.7,s
1. Cyclic compounds - Synthesis
Card 212

K i T-~ Kfi..Vq, j r- , 5,
AUT11013: :1, i ;-. i t 7. 7 7
TITLE: Tertiary A~ines of 3 e e 4~
:.~earr7 For BlockinC .1crve ~,anvl4a ao ~j
.Ykh Ceterotai:~Iov kak vnz;-~Czl.nyye
PERIODICAL. ZIurnal Obshchey Kh-'mii, 195F5- Vcl,. 2~1, :;r
03S2).
A33TRACT: The 4uaternary a=aGnia salts vi,-th their
were formerly considered the mGst sc;,~rcEi Of rr
m,edies for blocking BUt t-e ':.C,F~7 re-,-n* -- : -. r 1:1
;,,.-is showed that this may als-) 'he z:nse a;th -q.--
tort-Jary &mines ~referer~e 2~. T'It~~
earlier found that e.g. ti- 'e ~e--J-' ent 2---'--1-4--y--'L'.-.--1.--
lid ine (formula (a) -ossesses a
ity in the above-mentiGnei senpe, As --D:~-.-Cunds 3f
of activity are of Great imFcr~ancc~ for hy~pr*~-,--; --
was ex:;edient to syntheB-fz., of a
type, namely that of the pyr-'dine ari Z.r:-: 11y
the conversion of the hydr.--hicr--des ~r -~'3~ers -f
and 6-.'aethy'-picolini--- acid vtit~i diff,~ren+ wac
Card 1/2 possible to produce t'~,e a:-A-des ',I and in s7l-t~- --f

TertiLry A:mine3 of Some Heterocycl-~- as
Leans For Blocking Nerve
indicaticris in ~ublica-ion-, "-.at no amines can o~ - ai .,-,4
from the amides of pyridarr-arbcxy1_,_- a,:id_-- vita `-.e a--i
the aluminum hydride of litnium *ne auth~,,rs s,--
vertingmost of the obtained araides tc, t,-,e anlne.-
although the yield or. that csc-sion -ra,9 small and 'ry-17---d-
occurred. The reduction of the 8~M4dee -,f r-cer4.d_-n:ar'_-,~xy_1_:
-00 yield
acids tools: place much ~e-ter v; i t-. F ~, s and ~_as-
lation (IV). The pharmaco'og,--al InireSI".~ati--r- ~,f the -y-,d
ine and piperidine wl,.ich w-ts p,,rformcl ~-v
Sharapov showed that 1
aminomethyl)-piperid-ne ~,:V d) poqs,~sses a
the abova-mentioned Sen6e ~ha- 4~ evcn 'en
that of to trae thy! ounmonium, udido. Ther-e are I lj~le i-.11 r
references, 5 of whi7h are SlaviT.
ASSOCIATIOL. A22 Mdan Scientific Chemical-Pharmaceutical --.en
Ordzhonikidze ~Voesoyuznyy
-farmatsevticheskl4y institut imeni 3. Ordzhonik_'dze~
SUBMITTEDi JanuarY 7, 1957
AVAILABLE: Library of Congress
Card 2/2 1. Chemistry 2. CYGRG compounds 3. Amides

uT-40RS: _)jikitskaya, Ye. S., ',7i-'-lina, Ye. Ye.,
Furshtatova, V. Y&.
TITLE: Synt'lne.3is of t-e F.--_:_~,,.zines And Hydr-~zonez; -if So-.,v.
_yclic -ind Aro~~at_'c A2_'2o (Sintez jidrazl~ov i 1~illrazo.,.ov
nekotorykh geterotsiklic*r.eskikh i aromatic.-.,~!sir.-.
PERIO-~'C'AL: Zh'arral ots,icney khi,7ii, Vol 26, Nr lo,
P5 2786 - 279G 1,:SSR)
ABSTRACT: In earlier investi ations (Ref 1)' '.t was sa,)w! , t..at
t e qydrazi-.e of isonic,~tinic ac;d an,] its zones
dev,:lo~ an antitu,ercul%r activity. it w_s, t_erefore,
of interest to tne a!ith:~rs to syntnesize t-e rqdrazl~.Ies
and t;ieir deriv_~tives of tine pyridyl-4-acetic aclu,
_Lc-4)-propionic a---:d,
~-(pyridyl-4'acrylic and ~-(pyrid 4
as these differ from t,.e isonicotinoyl _-ydr~.,zor.e o-1y I.y -.-.e
presence of one and more -.,etiy1 j~roups ',_-etw,~er. t..,,~
pyriline nuc--Ie,,,s af:d t'.-.e
it was desi--,ed to o,.ti-.in h.wdrazides
from -ci!r, of tl-.e py,-,rridine and quinuc_'_`4_:.e s,.r1-S
ir. to expl-Akr, t*,;e e", ect of t..P :-. :.t
on t'.-.e biol-j Q*.-'e-_t of

of t-e Hydrazines --ind Hydr~zones of S,V, -,'0-26- 'c-'
he~,,?rocyciic and Aro7~.utic Aci`-j
coml,-ire in rez-)e,~t wit:~ t`-2
cUIIpou---.,O of t,-,~ 0
~,ydrazides of the acids aere
isonipecotinic, pyridyl-4-acetic-, pi~eridyl-,'-acet**---,
P- pyridyl-4~ pro~ion-`c-, P-(piperidyl-4);~ro~ionic-,
~-~~yridyl-4)-cryiic-, 6-met~-,yl picolic- ~-nd a- ~ui-
nucl-~~ine carboxylic acid. As t-c- p-nitrr)-'~IenzOic
is clcsely related to t-e isonicatinic -Icid, ills
9-ydrazide -and hydr:a70n~--S viere also synt`esized to
II .. -
explain its str,,cture and activity. The synt-egis
of tale hydrazides was carried out by the reaction of the
ethyl esters of t-le acids with hydrazine hydrate in
alcohol solutior. (aefs ',6) alrea:ay earlier syznt-ie~lze!
by the -.uthors. The suh-Scquent reaction of tne
wit', -iario,--.s to t`c- ~-.,~-,Irazones. The
j
Co.-.st-nts 3f t~.e o'-It~~.J~,ed -c's, an-~Iyses --nd yi~'- IS
are &.4ven 4-:. ta"' ~s 1-4. 'L-e bi--c-Lical inve-- ' 4. - -, ' -: ~ :~
of t..e -~nt _4 ar act ivity 1 t-- t-- t:.e.:
u r e 7 - C e J ~- ee C t 11, c
2, der,'-,, tivt~s of T'-

t 3 of tne z
e o c I I c d t 4 C ;L
w. d t
ASS A7, V3oLioy,.iznyy
t4 c', ,e 3k i y i ,'t - ~',i t 1' "!.-4
Scientific e
3.3rdz'-.oni',~iJzc)
S U B:,* I '-- T E So,te7,*-er 21,
C'I r -1 .71, 7

7TIV) RS: Jikit--~kavr!, Ye 7. S., SCV _-)Q 1-7.A
(u b t 9 u -1,
T I TLE: Bicyclic Syst,,mg Derived From 2,6-Liti,linp ('~itsiL:Ii-1,,es~iy-p
sistemy nn bg%.- 2,6-lutidina)
7, -)nFinc ant
II. Synthesis of thr? 3,9-0xazabicyrlo-[~ ''' 1]-'T,,Its
N-Derivatives (H. Sinte7 -non,ina
i yego N-proizvolnykh)
PERIODICAL: Zhurnal obshchey khirnii, 1999, Vol 29, "Ir 1, pp 124-1?9 (TJSSq)
jn
USTRACT: In continu:-ng woric/the synth,?3is -.,f "he 'hicyclic syqt,~--i!; derivel
from 2,;-lutidine the al;thcrs cbtpine~ ri new cou~nounl, the
3,9-oxazabicYclo-(3,5,1)-nonrine
CH) Mi CH-
6- '-
H2 .1H 0
9 D],
CH 2 CH CH2
Card 1/3 The diethyl ester of the dinippcolini-7 rtrii, oht,in.-?! fron

licyclic Systems Derived From 2,~)-'.utidinp. YV,/7-4_-,-)_1-29 '7
II. Synthesis of the 3,9-Oxazabicy,~110-[,",3,I] -Nonanri in-i rts I-Der;,vxiti-.-~s
2,6-lutidi,-te, was u3el -,is initial product (Ref 1). By tale
reduction of the Pthyl estr-,r op ~M7, ici .1 wish -!luminii-i-lithi-
u!n hydridF~ in eth-r 3olution compound (1) (Dhtiinei which
yielled (II) by mpthyl-it'. )n. 9y the ~ictio-: or thion 'yl chlorile
in the hydrochloriles of (I) and (II), ~III) an,' (IV) -,vpr,,
formei. On loneer hoilinr cf (I) with gulfuric cii r,,,', result-
ed, a slightly volatile, crystallinc, arl 3-lt-1nr-iiqr- ;roluct
(on nitrogen), from whi-l-, someofits'l-substitutel 1,2rivativ?s
were obtainel. From compou.,.d (I) t~.e nonane (VI) wn,- fnr-,e~ by
formic acid and formalleh-le. The sulfuriznt'on yiell,,~!
N-sulfo acid whicl~ .,ins sepnrnt.,d in tl'.p forn 0!' pot'i.,3,ilim
salt (VII). 1~y the reiction of (I) with r"-laric -1-7!i1
anhydride of rr,)-ionic acii ~n Pl'.,ilin,~ -neli,:-
subsequent boilinf~ of the r,~sultirip.- rrnido ~~f '1-i.7 acLd with-,
VTII) a Ix ) 710-e
piper~,4i.ie -liethyl-iine the com7~-~unds ' ni ( T
formed. '_V r-Iliction of' thp -iles obtain,~! with ~Jurriinu~i-
1 1. . r,,,-i c t i r) n
-lithi,rn h7rdriip (X) 9nd (XI) werp svntha3izol 7~t,
o f an e x c e ~~ s o f i t h -4 i c h I o r i c a c i d an' Y1 r i d r, - ~ - I u ~a r i c
n nd - I i p i