SCIENTIFIC ABSTRACT FOLDI, MIHALY - FOLDIAK, G.

• Document Type: CREST
• Collection: Scientific Abstracts
• Document Number (FOIA) /ESDN (CREST): CIA-RDP86-00513R000413420005-2
• Release Decision: RIF
• Original Classification: S
• Document Page Count: 100
• Document Creation Date: November 2, 2016
• Document Release Date: August 23, 2000
• Sequence Number: 5
• Publication Date: December 31, 1967
• Content Type: SCIENTIFIC ABSTRACT

FOLDI, Mihaly, dr.; ZOLTAN, Ors Tamas, dr.
Effect of byalm-onidase on the dispersion and resorption of radloacti"
proteins injected subeutaneousl-jr. Orv. hatil. -103 no.14:636-637 Ap '62.
1. Szegedi Orvostudomanyi Egyetem, JI Belklinika es Budapesti Orvostu-
domanyi, Egyetem, I Belklinika.
(PROTEINS metab) (HYALURONIDASE pharmacol)

SOLTIP Ferenc, dr.; F-P.PI Miha3y, dr.; Technikai munkatars: BRAUN, Erzsebet
Effect of hyason on low-voltage ECG tracings. Orv. hetil. 103 no.15:
681-684 15 Ap 162.
I* Budapenti Orvostudowaqi Agyatem, I Belklinika,
(EMCMOCARDIOGRAPHr phu-macol)
(HrALURONIDASE pharmacol)

FOLDI, Mihaly, dr.; THUWISZKY, Karoly, dr.; VARGA, Laszlo, dr.
Recent studies on the role of the lymphatic circulation in the patho-
mechanism of cardiac edema. Orv. betil. 103 no.16:727-729 22 Ap 162.
1. Szegedi Orvustudomanyi Egyetem, II Belaogyaszati Klinika es Gyo-
gyszertani Intezet.
(HEART FAILURE CONGESTIVE etiol)
(LYMPHATIC SYSTEM die)
gcg

SZEGHY, Gergely, dr.; WANDA, Endre, dr.; FOLDI, Mihaly,.dr.
Effect of ijympathetic block on papillary and retinal edema. Orv.
hetil. 103 no.33:1553 19 Ag 162.
1. Szegedi Orvostudomanyi Egyetem, Szemeazeti, Ideg- es Elmekortani es
II. Be2klinika..
(PAPILLEMM ther) (UTINA dis)
(ANESTHESIA CONDUCTION)

dr. KU11WI , F,, , dr. ; SZEGHY, G~~ , d rG-ULEI IT, A, K-0211A, M
dr.; POMRAI, M., &.- ZOLTAII, O~T., Jr.p- VARPjA, L.,
Anatomical, histological and axperlmental data on tho fluid circlulation
of the eye., Orv. hetil. 103 nc,,38;1781~-1792. 23 3 762.
1. szog6dl Orvcr-txvt';'!~~ 'ArIji 'EL'yetem, IL iii',Ikltallc~,, Szw~adhfflok o~i
Anatomiai Intezoi .
-Ief L- (EYE PROTEINS) (LIMPIMIC

LJO I P1
rHU,,GAR, 7
OBAL, Ferenc, MADARASZ, 13tvan, ZOLTAN ORS, Tamas, CSANDA, Endre, FOLDI
Medical University. 2nd C10le-o-f-Tnternal Medicine, Institute
of Physiology and Clinic of Neurology and Psychiatry (Orvostudomanyi E-
gyetem II. a%. BelklWkaja, Elettani Intozete es Ideg-Elmokortani kli-
nikaja), Szeged.
"Effect of Cerebral Lymph Node In3ufficiency on the Disposition toward
Cardiazole Induced Spasms."
11~4apost. Kiserletes OrvostudomaDX, Vol 13. No 2, Apr 63, pp 196-i9q.
Abstract: (Authors' Hungarian summary] Lymphadema, following after the
,ligation of the lymph nodes and vessels of the neck, results in an en-
hanced dispositim toward car%LUzole-induced spasms.-Of 4 references.
one is Hungarian, the rest in Western.
. . . . . . . . . . . . . . . . . . . . .
Mik"TS-1, U

YOIDI' M.
Sodium retention and oedema. Acts, mad. aced. sci. Hung. 19S
Suppl:55-69 163,,
1. Second Department of Medicine, University Medical School,
Szeged. (EDEMA) (DOSIUM) (ALDOSTERONE)
R, ~R-
R
-_3

hUNGARY
'L
mic Clinic and II. Medical 61VTc-(Szegedi Orvostudomanyi Egyetem, Szem-
klinika es II. Belklinika).
"The Role of Lymphatic Fluid Circulation in the Absorption of a Protein-
Solution From the Cornea."
Budapest, Orvosi Retilap, Vol 104, No 43, 27 Oct 63, page 2035.
Abstract. The current view, that the lymphatic system plays no role in the
fluid circulation of the cornea, is disproven by the experiments of the
authors. The rate of absorption of 0.1 ml homologous serum added to the
cornea was found to be very significantly decreased after the lymphatic
vessels and nodes of the neck of the animals have been tied off. No
references.
SZEGHY, G., ZOLTAN, O.,T., FOLDI,~6; Medical University of Szeged, Ophthal-

SZONTAGH, Ferenc,; VARGAO Uszlo; BARDOCZY, Arpad; Fppl,, Mihaly.
Effect of oral gestagens on the anaphylactic reaction in
rate. Kiserl. orvostud. 16 no.2t232-135 Ap'64
lo Szegedi Orvostudomanyi Egyetem Szuleszeti es Nogyogyasaa-
ti, valamint II, 92t, Belklinikaja.

h
FOLDI, ~~haly,__~r. __ , _
Some problema of 1~mph eiraulation In the kidney. Orv. hetil.
105 no.39104-108 19 Jal 64.
1. Szegedi Orvostudomanyi Egyetem, 11. Belgyogyaszati Klinika.

FOLDI,M.; OSAI-IDA, E.; TOTIltK.; OBAL.,F.; 140AFASZ, I.; ROIOW'YI, Gy.;
--VARGA, L.; WAGNER,A.
Melkersson-Rosenthal-Miescher syndrome. Orv. hetil. 105 no.6:
245-250 9 P64.
1. Szegedi Orvostudomanyi Egyetemp II. Belklinika, IL Foga-
szati Klinika, Elettani Intezat es Ideg-elmekortani Klini~a;
es Pecsi Orvostudomanyi Egyetem., Korbonctani Intezet.
M ~Qz

SZEGTARI, M.; LAKOSj, A.; SZINTAGH, F.~ F I- M-
The active function of the subcutaneous lymphatic vessels of
the human lower emtremity. Acta, med. Acad. sci. Hung. 20
no.2t2O9-213r, 064
1. Department of Gynecology and Obstetrics, and Second Department
of Medicine,, Univarsity-Medical behool.. Szeged.
i-RR

HUNGARY
-FOLDI-MihAIX, Qr of med. sci., -jHURXISZKy, Karoly, SZABO, Mihaly, ZOL-Lpj;, 0.,,
Tams, SAGI, Istvan; Medical University of Szeged, II. Medical Clinic and
Institute of Pharbacology (Szogedi Orvostudomanyi Egyetem, II- Belklinika es
Cbrogyszertani Intezet)
"The Effect of Butylsympathon (BON) on the Volum of Plasm Flow Through the
Kidney and on Renal Function in Hemorrhagic lVpotension"
Budapest,, A Magyar Tudomanyos Akademia V. Orvosi Tudomanyok Osztalyanak
Kozlemenyei, Vol XVII, No 1, 1966, pages 89-92
Abstract: Juthors' Hungarian sur-mry,7 In the presence of hemorrhagic
hypotension, an elevation ims noted in the rate of diuresi5, sodium ex-
cretion, PAH clearance and glomerular filtration in response to BON admin-
istration. These results are not changed, in principle, by the fact that,
because of the high degree of oliguria in cases of untreated hemorrhagic
ypotension, PAH and creatinine are unreliable indicators of the renal
k
plasma flow and of glomerular filtration. On the basis of the results, the
compound, ,4iich is practically free of side effects, should be tried out in
human shook therapy in combination with fluid replacementy 3 Eastem Eumpean.,
1 Western references. &nuscript received 23 Jul 65--7
Anatoqr
HUNGARY
,F~OJ~DI,~.Dr of med. sci., GEUMTp Albert, Cand. of med. sci., K0214Ap
larta, POBMAIv Maria., ZOLTP14p 0.,, Tamas., OSANDA, Endre, Cand. of mod. sci.,
'arta. ~OBMAI.
Medical 'University of Szeged, TLI. Medical Clinic,, Institute of Anatomy, and
Neurological and Psychiatric Clinic (Szegedi Orvostudomanyi Egyetem, IIe sze
Belklinika, Anatomiai Intozet es Ideg-Elmokortani Klinika).
IlRecent Data on the Anatomy of the Connection Between the Brain and Lymphatic
systemll
Budapest., A Magar Tudomanyos Akaderaia V. Oryosi TudoM2Mk Osztalyanak
Koziemenyei, Vol XVII, No 1, 1966, pages 93-ICO
Abstract: Juthors, Hungarian summrZ7 By the method of experimental lymphatic
edema produced by "self-injection with lymphatic fluid, 11 the lymphatic vessels
in the substance of the dura mater at the s1mll base and their connection vith
the tr. lymphaticus cervicalia were demonstrated. In contrast to tha un-
certanities and inadequacies found in the liaterature, this observation provides
a morphological oonfLrmation of the lymphatics in the area of the dorsal sulcus
and also explains the severe morphological and functional changes seen after
radical 3-1 tion of the cervical lymphatic ducts. AU 9 references are
=script received 23 Jul 65.7
Western.

HU1~GARY
I=L~.~halXL Dr of med. scl., ZOLTAN, Ors, Tamas; Medical University of
Szeged, II. Medical Clinic and Institute of Biochemistry (Szegedi Orvos-
tudomanyi Egyetem, II. Belklinika es Biokemiai Intezet).
"Mechanism of the 'Barbiturate Resistance' of the Pasteur Effect in
'Cerebral Lymphedema'.1'
Budapest, A Magyar Tudomaao5 Akademia V. Orvos! Tudomanyok Osztalyanak
Kozlemenyei, Vol XVI, No 4, 1965, pages 377-384.
Abstract: [Authors' Hungarian summary] 1) The aerobic glycolysis of the gray
matter homogenate of both normal cats and cats with "cerebral lymphedema"
is slower than that of the semihomogenate. 2) A statistically significant
inhibition is produced by the gray matter homogenate of anaesthetized nor-
mal cats on the aerobic glycolysis of the gray maLter semihomogenate of
anaesthetized normal cats. 3) The inhibitory effect of the gray matter
homogenate of anaesthetized cats with "cerebral lymphedema" on the glyco-
lysis of the gray matter semihomogenate of anaesthetized normal cats is
more pronounced, to a statistically significant degree, than that of the
gray, matter homogenate of the normal cat, 4) It appears that. in "cerebral
lymphedema" the brain tissue contains some "inhibitory" substance. 4 Hun-
garian, 9 Western references. [Manuscript received 24 Jun 65.1
1/1 - 5 -

VARGA, Dr., FILMOVIC11, Istvan Dr., ZOLTAN, 0. Tamas., Dr., GABOR,
k' =' Er' ' -
Miklos, Ur., and F%JUU& F11.11 Second Clinic for Internal Me-
dicino (11. BelkrtiffU rector. ;-ZI-J. Mihaly) and Clinic for Obstetrics
and Gynecology (Szuleszcti as Nogyogynazati Klinika)(Director: SZONTAG11,
Ferenc, Dr.) at the Medical University (Orvostudomanyi ESyetem) in Szegad.
"Invcstioation of the Concentration of Carbohydrate Bound with Sorl.11- -L.A-i
Lymph-Proteins in Experimental Inflauwwtions"
Budapest, Orvnsi_H &o 2o, 26 Jun 1966, pp 1203-1206.
- -_ qSjI12, Vol 07, N
Abstract: Tife puv-:Ln-su&ar level and the concenzration of carbohydrate bpund
with the protein of the ductus thoracicus showed an increase in animals experi-
ffenLally -cLed to turpentine inflammation. On the Other hand, the -Iyco-
protein conLenL in the truncus raervicalis f rom the inf lamed area was -; i -11 L ri-
cantly lower, even after 24 or 48 hours, than in the serum or in the ducLus
thoracicus. It was assumed that- the organism retains glycoproteins in ~*,:- _-
flamed areas for use in the regeneration processes. 28 references, inclit'. .;6
2 German, I Hungarian, and 25, Western.

;, UNC, A -IZ
F_C VilM,~N*-.SZKY, Karoly, ZOLT N, 0., Tarrias; Yedleal University of
Clinic anei Institutt) of Plharmacolo,y (Szi,~:i:di Orvos-
tudomanyi 7gyet,~m, IT. sz, Rolklini''Ka es Oyo,,yszertani Intezet).
"Po'havior oC the j3loo,.1 Fre3surp ancl o.&' the ExtProceptive Bloozl Pre3aura
-veflex in Ca~;es of Lyripho~,enou!5 "neephalopal-hy."
Budapest, 'Kisprleturs Orvostudomany, Vol XVIII, 'No Cct '06, pa:-es 471-476.
Abstract: [AnVhors' Hungarian swimary] 1) After c-Prvical 1,,.-,nph blockajr-,
statisticall.y- si:,nilftcant fluctuations in blood pressure can be observed. 2)
In lympho,-.--..,-,ou!3 oncnTYhalopathy, hLher than normal blood pressurc incrr-.as.-;
an'-1 a !Pcrcase~! ble-pharosparurtim can be notcd in m3ponsc to the introduc-
tion of a drop of pain-Inducinr materitil (rnpsaicllne) Into the ny,~'- 3) This
ohenomenon by "he authors as thr! r:~sult of an unoct In thr~
--c~=ntral autonomic to ~erla`n central
* lib. ho'o: .
i-,-.u L iu,-., and o' morp;l L :-cal
nervou5 svstr-mic ~-,t-.,uzturas. 8 Rungarian, 13 -,'r:stF,-n refr-.rencas. F" nuscr4ptt
receivedl 29 5ap 6
W

F94PI 1 pal
Now products of the Beloianniaz Telecommunication Factory.
Radiotechnika 3J* no.8:302-303 Ag 164*

IFOLDI., Paip oklqveles gepeszmernok
L
Analysis of new products from the point of view of Otandardizatione
Szabvany kozI 16 no.71109-113 JI t64.
1. Belolannisz Telecommunication Factory, Budapest,

FOLDI, Pal
Dependability in electronics. Radiotechnika 14 no.l2t2 of cover
D 164.

01
u~!t---, (-,C 0~ nr;roer'ng Factory.
I,,' no.Q:

FOLDly PaLl
Report on the conference on semiconductor and electr3n -,uce
manufael~ure. Radlotec~mika I../. no.113406-407 N 164.

FOLDI, Pal
An account of the conference on durable elactronic da-zices
designed for general use. Radiotechnika 5 no.5:170 Yq 165.

FOLDI, Pal
Co-f',irtwe on transformer, roactor and ferrite production.
Radiot-chdka 15 no.1:2 of cover Ja 165.

FOLDIAK, Gabor
Nuclear chemistry research 'v*)Ylng-radioactive isotopes
in the chemical industry in guftolto ;Naa ken lap 19 no.81
397-399 Ag 164.
I.-Isotope Institute, National Atomic Energy Commission,
Budapest.

FOLDI, TAMAS
Asvanyolajternakek kenctioxidos extrakcioja; irodalmi osszefoglalo
Veszprm, Hungary., 1952,, 104 P.
Monthly List of East European Accessions (EEAI) W, Vol. 8, No. 6, June 1959
Uncl.

FOIDI, TAMAS
Laboratorium form kontakt kiserletek; zarojelentes I
I
Veszprem, Hungary, 1953, 80 p.
Monthly List of East European Accessions (EEAI) LC, Vol. 8, No. 6, June 1959
Uncl,

FOLDI, WIAS
RepulomotorolaJok eloallitasa folYtonos uzemu oldoszeres finomito
keszukekekben; osszefoglalo jelentes.
Veszprem.. Hungary, 1955, 30 P.
Monthly Liat of East.European.Accessions (ERAI) LC, Vol. 8. No. 6, June 1959
Uncl.

FOIDI, TAMAS
Trikrezifoszfat mint uzemanyag adalek; irodaimi osszefoglalas.
Veszpx,em., Hungary., 1955., 46 p.
Monthly List of East European Accessions (EEAI) LC, Vol. 8, No. 6. June 1959
Uncl.

. ~ff

7~F&~ - j-, j7
, ~. .1 1 1

LLimiaLli2 I

HUNGARY/oraanic Chenistry. Naturally Occurrina Substances
and Their Synthetic Analogs. G-3
Abs Jour: Ref Zhur-Xhim., No 13, 1958, 43495.
Author : Foldi Z., Foldi T., Folcli A.
Inst :Hungarian-*cffe-my of Sciences.
Title :Confcrmation of Psi-Ephedrine; Copper Chelates
of 2-Araino-Alcohols .
Orig Pub: Acta chin. Acad. sci. hung., 1957, 11, No 3-4,
339-348.
Abstract: In connection with elucidation of the question concerning
the presence of an intramolecular hydrogen bond in Psi-
epOedrine (Poi-I) and ephedrine (1), a study was made
of copper chelates of I, Psi-I, and other 2-arAno-
alcohols. It is shown at (+)-Pai-I forrm a copper
chelate /-(+)-Psi-II_7, MP 209-2100 (decomposes;
Card l1r
51

HUNGARY/Organic Chemistily. Naturally Occurring Substances
and Their Synthetic Analogs. G-3
Abs Jour: Ref Zhur-Khim.) No 13, 1958., 43495-
from C~30H), insoluble in water and nost organic
solvents, soluble in alcohols, and containing (like
the other investigated Cu-complexes) two molecules
of amino-alcohol per atom of Cu (II). Under the
same conditions th re is f md from W-I a chelate
hydrate mp 1650~ (decomposiTs)_. By the
action of cold acetone (2:)-111 is converted to the
complex (� )-iv, mp 169-17117 (decomposes) (see pre-
liminary communication, PZhMim, 1956, 65o67). For
(,�)-III ther is known a solvate with one molecule
of C41i~, MP 157-158'0 (decomposes), soluble in organic
solvents. The authors note that the data obtained
are somewhat in conflict with the assumption (Fodor
G. et al., J. Organ. Chem., 1949, 337), that intra-
Card 2/6

IWNGARY/Organic Chemistry. Naturally Occurring Substances and
Their Synthetic Analogs. G-3
Abs Jour: Ref Zhur-Khim., No 13, 1956, 43495-
molecular hydrogen bond Is possible only in Psi-I,
but not in I. The assumption is made that, probably,
CUII -- a s~Uiong complexdr, impels internal com-
plexing of I notwithstanding the spatial hindrance.
This is confirmed by lesser stability of (t )-III
and (:!7)-IV in comparison with (+)-Psi-II. ( t)-IV
decomposes in organic solvents, 4 N aqueous solution
of NR,, in solutions of alkali tartrates, in aqueous
solution of (NHf)tS, In which (+)-Psi-Il is not
decomposed or is decomposed more slowly. Psi-I
reactgI with CuSO+ more rapidly than 1, since on
interaction of a mixture of (I )-Poi:--I and (I )-I
with an insufficient amount of CuSOi#.there is formed
(t)-pai-ii, mp 2o6-2070. The authors note that by
Card 3/(,
54

HUNGARY/Organic Chemistry. Naturally occurring Substances
and Their Synthetic Analogs. G-3
Abs Jour: Ref Zhur-Xhim., No 13, 1958, 43495-
mans of Cu-complexes it is possible to separate
also other diastereo-isomeric 2-amino-alcoliols.
Thus, threo- 'r)-2-araino-l-(p-nitraphenyl)-pro-
pandiol-1,3 threo;(*v2forns a complex, mp
153-154'0 (decompose ), of the type (+)-Psi-II,
while erythro-(� )-V forms an ionic complex, IMP
123-123.5" (decomposes), of the type of (� )-III
(without water of crystallization). From threo-
(*)-v was obtained a complex of the type (+)-Psi-
II with two molecules of water of crystallization,
MP 133-1340' (decomposes), which on treatment with
CI1zOH is converted to the more stable, anhydrous,
triins-form, mp 162-163' (decomposes). moreover,
from threo- (+)-V there was obtained a complex of
Card 4/6

HUNGARY/Organic Chemistry. Naturally Occurring Substances
and Their Synthetic Analogs. G-3
Abs Jour: Ref Zhur-Khim., No 13, 1958, 43495.
NP 2701. It is shown that 2-amino-alcohols with a
tertiary amino-group also forn Cu-corrplexes, for
exampleo a Cu-copplex of type (+)-Psi-II from (:t
N-methyl-ephedrine, mP 176-1770 (decoriposes). it
was found that amino-alcohols v:Lth a primary anino-
group form insoluble complexes only if at the C-
atom linked to the OH-group are present bulky sub-
stituents LQu-complex of dimethyl ether of (!:-) 0
-noradrenalin, of the ( !:7)-111 type, mp 165-166.5
(decomposesly . Ethanolamine (VI) forus with CuSo~
only a colored solution; benzal-ethanolamine does
not react at all (a partial coloration of the solu-
tion is due to hydrolysis to VI). No reaction what-
ever takes place with 2-phenyl-543,4'-dimethoxy-
Card 5/6
55

HUNGARY/Orgarlic Chemistry. Naturally Odcurking Substances
and Their Synthetic Analogs. G-3
Abs Jour: Ref Zhur-Khim., No 13, 1958, 43495.
phenyl)-oxazolidine and 3-amino-alcohols, for example,
2-methyl-4-amino-5-(hydrcxymethyl)-pyriiaidine, tropine
and Psi-nortrapine. It is shown that 3 molecules of
(t)-Psi-I form a complex with CoII(CoCl;~), which does
not rielt up to 270". All the investigated complexes
are decomposed by kS with liberation of the corres-
ponding amino-alcoliol. (+)-rai-II is obtained on
grinding 1.65 g (+)-I 'with 10 ml water and 1.25 g
CUS01-5HAP, adding 10 ml I N NaOH, and separating
the resulting product after 2 hours; yield qq~'-
Card 6/6

7,
IOr i - -4%?-.(J)/4E3d
'140. Addition of-hydrogen i0phi'do'-fe-the, ol'trile -- z ri
of Q~Isulphqnyl, 01,81111MI647by mt4al of Ifilasulphl4ric
11910. ) &. v U jju, 1-. 1, 6 1 it I. A. It 6 1 it 1.
AcM 'C'uA=L8A%a-Je~ns-* ScMffMffWf'ffftgRr1ca7. Vol
13, 1057, No. 1-2. pp. 111-116
A new reaction is described in tlw course of which
(me thlosulphuric acid Is added to the CN group of =
oulphonyl cyanamidies whereby very favourable y
of arylsal houyi thlouieaa form. The known decomMqI-
tion of thl~oaulphurie acid Into sulphurous acid and ele.
P
1, inentary sulphur could be completely reptimied by the
addition of sulphurous acid to the reaction mixture at
the start. The properties of scetyl sulphatillyl cyanamide
and sulphanilyl cyanamide are dtscuxs~d and the ass n I
new reaction mechanism presented. M.

J
Country :Hungary G-3
Catagory :Organio Chemistry, Natural Mpa=ds and their
Synthitia knalogues,
Abs. Jour. :Ref. Zhur.-MLUtya No. 6, 1969 19592
Aut,hor Foldi, Z.; Foldi, T41"FAoldi, A.
t
Institut. Hungarian Acaderay or belences
Titlo Chelates and Conformation of Cinchona Bases.
Ori3 .Pub, : Acta chim, Acaa. scient. hung., 1958, 16,
No 21 185-192
Abstract ; Confirmation of the previously determined con-
figurative relationship between quinine M, quinidine (II),
cinchonine (III), cinchonidine (IV), and ephedrine W, and
the relationship between epi.-I, epi-II, epi-III, epi-IV and
4V -V, on the basis of data concerning the formation by the
above-stated alkaloids of chelate compounds (ChO with Cu2+.
I-IV do not form ChC and are configuratively related to Vt
epi-I - epi-IV form ChC and have a configuration analogous
to that of Y -V. The capacity of f orming Chr, and hindered
rotation about the C(8) - CA) linkage in the epi-bases
suggest the assumption'of t.e existence of a rigid hydrogen
bridge -0-H ... N *- and therefore of the existence of a five-
Card: 115
~atg_pt
~ g ~

Country : Hungary G-3
Catogory= :
Aba, Jour. : 19592
Authar
Institut.
Titlo
Orig. Pub.
Abstract :membered ring which constitutes an additional
asymmetry in epi-I - epi-IV (N atom -- new center of symmetry
is compared with I - IV. Capacity of f orming ChC in the case
Df ePi-I - epi-IV indicates apparently that configuration of
quinuclidine ring, in the epi-series, is represented by the
formula A. This shift in the quinuclidine ring approximates
the OH at C t C ) and renders possible the formation in
iso-quinidl~e"Z and is'o'-cinchonines of a new seven-iLembered
ring by the action of acidic agents, 0.648-g epi-II are
ground in a mortar with 5 ml 0.2 M solution of CuSO., 2 ml of
1 N NaOH are added, after 2 hours there is filtered off a
Card! 2/5

Country Hungary
CatcSory
hba. Jour.
Author
Inutitut.
Titlo
Orig*Pub.
AbBtract
t9.
cn 0 H
8
H 8
G-3
19592
N
N
~8 ~IN
/9 0
epi-I 0 -api-II A
C9 atom is linked to residue of 6-methoxy-
quinoline

Country Hungary G-3
.~ba. Jour. 19592
liutaor
Institilts
Titlc
Orl,%. Pub.
Abstract :ChC of composition (C20H2302NOCU - 1-51120~
yield 0.? g, decompositicn point 150-1900. Analogously from
epi-I was obtained ChC of epi-I, decomposition point 160-18L4
and from the dihydrochloride of the double salt epi-I-epi-11
the mixed ChC of epi-I-epi- II, MP 125-160* (decomposes).
0.61+8 g I are ground for 40 minutes with 20 ml 0.1 N AgN031
after 10 minutes (600)'there is obtained a molecular
compound Of Composition C20H2jN202-AgN03-2H209 Yield 0-94 99
decomposition point 202-2050. Epi-II forms-an analogous
compound$ MP 1800 (decomposes). 0.648 g I are ground with
20 ml 0.1 N AgNO3 at 200, then 10 minutes at 70*, after
Card: 4/5

C3untry Hungary G-3
Catogory
Abs. Jour. 19592
Author
Inatitut.
Titlo
OrIg, 'Pub.
Abstract I hour added 2.1 ml I N WE and after 5 hours
there are obta~n6d 0.882 g ChC of composition C20H2-N2202Ag-
*H201 M? 1650. Epi-Ij yields under analogous conditions a
ChG of decomposition point 170-180*. Epi-11, diben.-oyl-d-
tartrates of epi-II and epi-I give a violet coloration with
a solution of CuSO4 in NH,OH and C,H,OH. Preliminary communi.
cation see RZhKhim, 1957, 71+559. -- ke. Tsve-'Ukov.
Card: 515

FOLDI, Tamas, dr.
nBibliography of economic planning, statistics and accountancy.,
1955-1958" by Mrs.Elemer Hajdu., Bela Hamori, and Gyula Harasztby.
Reviewed by Tama Foldi. Stat szemle 40 no.7:758-759 Jl 162.
1. Magyar Tudomanyos Ale-arlemia. Kozgazdasagtadomanyi Intezetenek
munkatarsa.
-g
:OE;;'.A~ nP

FOLDI, Tamas
Acce3sration of motor veh.icles. I. Jarmu mezo gep 8 no.3:82-85
mr l6i.
1. Magyar AsvanyolmLj- es Foldgazkiserleti Intezet kutatomemokeo

FOLDIY Tama~ _gepeszmernok
Graphic design of In-aking forces and locked gripping force diagrams.
Jail= mezo gep 10 no.10:368-373 0 t63.
1. MCGURT.
W
g

FULDIP Vilmos
The recreation service of trade unions is 15 years old.
Munka 14 no.5:2-3 ~br-1,64.
1. Head, General Directorate of Recreation Centers and
Sanatoriums, Central Council of Hungarian Trade Unions.

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LMOINA, RX-IGURMS acylat"I on 4k. 10 cc 1.7 1. o( a soln. o( I C. H In hl"Co. a,
Apr. 1, 1918. Nrivs. 6r W dry
the N storns by a sulfo &Z are trfttcd with NJI. or CAN I. ftfluxed 10 min, -4pd. in We" to a sirup'
thydral '11C411
aryl., or am Ines. p-AcN &S(NN - mixed with water, ruMxj, fij ey
sir 'IN, treed. washed4th water.
C(SlIONIll 1.5 a. re used 3~6 brs. with 11,0 10 and NI- and dried, give 3JS-3.40 S, ol the Are estef cj m
ji~ 114.11&0 (?A -0.3 cv, gives 1.2-1.5 K. gk~w.w WICC7,~Wlsol about 39".. IV.
& sapond. by boiling I be. with 1.0 v VAUI 1.
M. M. ~ .15 (or the Tbc Et ester bomolog of V gAve the Fj eskP Awdn of
resp. tautumcric(orm),nat diualved bycold 1.0,V NaOli- Vt. M. about 140-801. P-MINOCC111cligm..
t Emil ittv") In PlWc of 1110 as solvent also gave L P- llSO~NHCSNI1j and it pvt IV. P-MOICCONJI)C, .00
t 9.6 g. a
ifoxcillciticoNlicoll.SOIN:C(Scllio&it) Nil 114SANUCSNUm 3.31 .7 F. of a soln. of 1.0 X. U 1 100o
ile Z frouscil 1-1.5 b". with (1670 111011 50 and N11 hleCO, SD~-'* ale. 10 cc-, and dry CJJsN 1.0 j., rrfiuxed
3.0 cc. gave loo% Cent. 10 min.. then tmttd as above, give the "kardyiamino 200
00 j - , P-1110~. a
0 AroresulfocaNddoliko4zak 00- Sim Y- xdJOC of IV. m. about M5-7* (from &k.).
0 CCI -chlorocTclobexanone ci BY similar
I ,
Cl CONllCJl.SOjNllCSNllj and AcClIst Promdures. Ma and 2 ve the 4,5.
00 gave 2-JO-0-forboxyUryi isa)tkex*tdf&xamide14- Wramdkykne d&iv. ot U. V and CICHMlit give :-(p-
t 2f) P-(O- (gr - - j-
ll()ICCJtg- ire 0
il)Cjf, -.11CS-Vil. and H t4ve the 0-(arboxy- k*"Udsok.andj -(O-carbaxytwopfionylami )-3-p
s0$.% Yti -
00 hnzamide qo4of of Ul, m- about 190 HHOtCctft- *0
dyisulfonylithiourm and aculclio or Uyve
AM) 1.57 an 0 ale.
01,CONIOCASO,N)ICSN1110 box P)wid'Wjul offUssok or 441*
0 5 cc.. ,u
0 OJM 1. Of A 50% Soto. of In MeW, and dry Cs- Istvin FinMY
II.N* 11.5 K.. relluxvi to min.. cooled on kv I hr.. filtered.
.0 ls-- and wa .%bed with " cc. ice cow 80% Bic., give 1.32-1 .50
o( tile 4-3re derip. (IV) 0( its, m. about W5'. Similar see
, KhMICS.
treatment. of (CHICOMIC41I.S Nlft-#) P- Igoe
'Alt: C11
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FOLDI, 7. 19,118
(Res. Labs. Chinoin. Chap. Pharmaceut. Works Ltd. Ujpest, liunEary)
flInvestigations Relatine to the Synthesis of Patulin."
Jour of the Chemical Society 1948 (sept)
pp. 1295-1299 0
Abst: Exc. Med. 1l,, v01- 11) NO- 10) P- 1360

J.
k". 6WMe (1) or their esters with sulfasele acids or
U1804 us treated hi the Presence of Mercaptatts with a cata-
lyst to cause a Beckmann rearrangement. The thlotmido.
saw formed Is apd. &W treated in the pmence of a sal-
.vat with HNs- E.g.. to 22.6 a. I In cc. dry CHCJj
Is slowly added (90 min.) with vigorous stirring and cooling
at -10 to -2V 37 C. PhS0jC1 [a 30 cc. dry CHC1j and
80 cc. dry QUA stirring continued 2.5 hrx, at - 10*. and
the soln. Is added under reflux with stirring to 40 cc. EtSH
In 30 cc, dry CHCh. warmed to 45'. bolkd an a water bath
I bree., Gvapd. to 120 cc., 130 cc. 20 KOH added, the
sq. pbase repeatedly shaken with CH91e, the CHClv exts.
combined, washed with wetter, dried with KtCO.. filleted,
the Aftrate d1old. at 60 mm., and the residue distd. to yield
'2&4 C. colorless %pid, be~ 97-1011, with a disagreeable
odor Identilled u lR*C(SR0-(CHJt1Hs (H). MeCA-
W6 my b. used 1. place of PbSOCl. U (?..01 mole) Is
treated with 22 cc. (0.015 mole) HNs In 3 vo .-% t HC4.
allowed to stand 42 hrs., then heated to 40' under reflux,
kept I hr. at 400. 1 hr. at 65'. and I hr. at 710'. The
solvent Is distd. off, and the residue distd. at I min. and
retrysid. from EW gives metmtole (about 0.01 mole
.11 Cyclopentaftme texime Is Used as the starting material:
tctrumethvienetetninle I% obtained. It the 2-Nle nr 4-Me
derivs. of I are u-icil its Marting materlabt, the mp. mptk% I-
tetrazolest are obtained. IsMu Fin.ly

d-Alkojry~s-balo scids and their derfradvists. Zoltj,.
Fali, -,Hwg. 139,710, July 15. 1%49. a.0-Uniiiiii-F"
4ritit'nr their detivs. ore tmitetf in the lirtsentv of Ph
4-tunpI4, with hypull-ilite r-ters, e.g. McOlIt. or &k-.. *,
hItOll, and halogens. (1) Pb(..X(hl, (17 g.), iftra
ibrougha bi. sieve awl roade up with lix)
fill. %frOll to a pulp, is Inixed (ice cotiling) with 10 x
Nfi,,C:ClfCOtglf in 411 nil. MeOlf, 5 nil. Its, added slowiv
during semill hrs., the tuixt. let mand overnight. riltered,
the filtrate neutrAiied with about 70 nil, of 2.6 N NA011,
the MeOlf distd. off under vacuum, the all, soln, filtered,
~uci,lified with 5 N IW4 to Congo p2per. the livid. NleC~
(OXIOCII&COill extd. with ether, the ether phase (tried
with NuSO.. and the ether d6td.. giving an oily mas,
(its 1.) which solidifies to a cryst. product. (Z)Thesam,
lots. eki applied to rfolionic acid givro INCII(Mlej-
ClIfIrCNI, P! 1.111:01COill * MCM111CIIIII
'OhIl. 14) SA"Ir A, M but wish = Instead J Ph
i%(h),. (5) Suisse us (1) lmt with CI instead -it [it,
giVi"Ir (6) %Ault as 0) I'll?
with Nfr&C:CllC0,%f, M When RtOll is used illItCA-
4 McOl I in any 4 the 41mve esamples. the atialngmt, ;i
rtlus lavin Finily
- 1y .. . . . . ..

r u I- U, -T-
The chernistry'Of lurpj4erlyatives). _.I4,Xppjx A
t Z. '11M, 1=17.4 I* ' F t N-1
i e% Buda;
T
1)jkku% 4, rp,
Alk ~hip'fl E.-Hu ng. 3, 15, -rR I
~acctyloxct,4nc (1) is cleaved by dil. HCI to give mainly the
ether (11) of IlOClljCl-ftCllClAc (111) (Cf. Stevens and
Stein, CA. 34, 02701). However, fractional (iiqtn. of the
crude 11 vield-, a &m.111 amt. of a compl. (IV), CiTITC10. b"
d,, I. iv). corm5ponding to III lesl I Illoic .4 11-0. 11
wills dr... Itcl at 0' rivtn (151~1,` !-meIhv? --"3-
h;4rofuion (V.I. 4, ako nljtnin~d in 8217o virld by
beating 11 with SOCII. V Or, K-) heated 0.5 111. Will 8 ItIl.
dry pyt Wine yields 10.2 g. IV: V 6 ah o cutivertM to IV by
anhyd, KaOllz ur wihyd. NnOAc. 11 (10 g.) treited over-
night with 20 ml. conud. lfCl yields 8.5 g. C1C11.CHC11C7-
Ac(V`I)' th,58', des lZ39; 111.2z. I heated with 32m). coned.
JICI gives 7 V. VI. Ilt-fluxing 15.5 g. VI I hr. with 8.2 X.
anhyd. NmOAc In 20 rid. AcOlf gives 6.4 K. AcOC11,CHCH-
furan (VDI), 6,5,75'. is obtained by treating V with NaOEt
It EtOll. or by refluxing VII With -tb-.. HIM. U and IV
with (FtO)jCl1 and PhSOJI also give VIII. 2-Afah?'i-2-
methoxy-3-chloroletrah)-drefurapi, b7W, isobtained byboiling
IV with MeOH. VI and V11 are converted to the correspond.
ing thlazole derivs. With 112NCSNtfs, J. L. 0-B.

lt'~

oinn Iv,.
A
(id; of thful to III,- 'jnuU~! m!.
Ailuitit"'ll II! lw)L!j"ycn ~vlildq ti) -1 11

I'l. P.72

:;-!4
A 7
I it

Y A it
k Aor
11 C N I C Ii
r 15,
j Vifi: cl-fI t"

1,0A

The mirl. I I'); fit t t. .5 71!0'
!qd It'l. NCI !:tt 2, h r-,
,.
C5.%,
f1cl, tll-'~ pilt. J~ 0 ;1;;~j
j.1, J
1 .83 Z. C

i-cwf, -8-1.
followed by additIcation of the ext.. pvc a gut-11Y 111359
which custd. to give 0.3D g.
(VI), ir. 116-1$ (1 g,) lmwd with
2.5 nit. Ac~O '0-30 min., gave 0.831- g.
(VII), in,, UO-I' (from nn. 'McOlf);!
a ioba. of V11 and III gave a 10' in.p. deprmion. 'I'll a
soln. of I g. V In 30 nil. EtOll iva, w1ded -10 all. 11.0. 111,til,
50 int. 2 (1. FeC4, Slowly and with ctwlitu; tu givi, 0.3 g.,
% q
(Vill), ill. 12 (fromn hot ~q. W011). A solij. of I g. V
ta sq. Et-011 rcj1uKW I lir., tlj.t -*In. extd. idth AvclEt. th.~
ca. uvapd, to drync~.-, and Vr,O edded to the rz~idnt rsiv,,
0.2 1 q. A1e,C(SJ`1)C110W111c)Co.11. ill. I A ~,Ilii.
of 0.7 g. III ill 10 fill. Die. Y KUSH, t vaptl. to flryuc~-- aftvr
21 hm, acidillml with -1 !ill. ".51V HCI, und ppt, 1:jk-CIE Uf) ill
AcOlit, gave 0.4 g, VI. ~ WIIF~l lWil-krdlY 1!M tVrk:LltiC
agaiwt slaphy""C"Cws cureas, VI Ie4~; --u, and Vill vvarly
inacti-. J. P, Da:%.J.y

FOLDI, Z.
"Addition of Thiol Compounds to the Double Bond." Pt- 3- "Addition of Hydrogen Sulfide to
Azlactones." In Inglish, P. 501. %dapest, Vol. 3, no. 4, 1953.
SO: Basi laropean Accessions List, Vol- 3, No. 9, September 1954, Lib. of Convess

Addition Of WOI COMPOUCL(ISI tO Ule (1104648 b4nd. III,
Addition (if hfpd Claulp to W,
-.1noill VV4 Plest- U
't- LIM
a, A af A-z . 1 C44. -
-M9530 Prignin
Moli. S7V I * ; Ct. 4-1 . iY, lw.".-
Tilt! addu ,I Ills to azlactonci loxazoloncs) %vith an all.
phittic' :ov-stitnent ill tilt,, 2-1mlition was InvOtiVited.
1) Yfeldext with AcO 2-
which was
~~xivcrtud by RIS In neutral atc. soln. to
arid (111), or Ill allk ineslia let
-it; of Aft, C: C(A`HAc)COtS11 (IV) "'I Al'ac-
~SH)Cf11,NH'A,;)(;0SH (V) 'and an intraniol. distilfide,
Me;;E-5.150~11MIAI (VI). 1 (14.7 9.) anti 35 cc. A,,CJ
fheated tintil soln. take-3 Place. and the :;(Ali. din'tj. give
12,9 g, (03%) 11. Colorless mobile liquid (when inelted)i I;,
(12', bi 66% b, 75". in. 42-3' (in.-tome Instances, m. 43-5*),
readily so]. In tile cornmon org. solvents except petr. etf
d I er4
paringly Fol. in ITiO; tile ca.p. 1-1;i 'n Cto
e4, ojdayjj ve I
"" I
the 11 is kept over Plo,, which b Probably the result
of a polytacritation catalyzed by acidsi ,
frictlow -bf -11
contg. orne Ac,O wcj-e more rapidly cotivetted toa product,
15,51-430', whlch %va-, sparitigiv stil. In MeOll fir Mcle
g.) IT% 4 ce. I*lc%CO heated a few mill. with 4 cc,
ILO anti the tilixt. let 5tand several firs. denosited, 1.5 g.
I (ricarly IWIC) Aroic: C(,V11AC)C0jr (VII). title lustrous
flat needles, in. 100' (deconipti.) frcerystd. from aq. Melco,
ill. 200' (decoxialiti.)). Dry H&S pa~.ied into 13.6 g. 11 in
20 re, NTeOH with m-oling it n Of I mote was absorbed. the
mixt. Itt stand overnight, th ~Ieoff diit,l. off, tl,,- r,imrrv
rasidue kept in mcua -, and 0.1 of the reililling cryst. Solin
ti-iltirated with cold Ltlo gave 03 g. 111, ril"efus,;Upic 1110;n.
bic cryst'als' M, 135-W, so
1. in 1110, givii with Feel, 0"
PA grLenish color and with AgNO, a smail amt. of pale.
,h.r
yell')vv ppt. whih filCrM3Cd On heating all(I blackened-
remahilog 0.9 of the crude product heated 10 1111111. in 16 cc.
ff%O or; the water bath arid c(x%led, and the resuffing solid
tv.tshed with IltO and dried gave 16 g. tiL-acttylpcljIcij;'
11mille.. hIeiC(SH)CH(NfIAc)COH (VIII). in. 187.5
(decompn.), Sol. in EtOlf, moderately 5o1. in ITIO, hardly
Sol. in 1340, MOAC, CIICI,, rc2dily scil. ill p%,rHin-. jilli-14T
-.,Ppts. with HgCl, (white). AgNO, (pal- ii L~
C), (whitt); When boUejj ~-iith A 1- l-'.
yellow ppt. blaclea,4A: FeCl~- &-a,.e ~ t~iiu~iQn'
followrd by the pliti. of a white Na
'in aq. NaOff gave a Nelisill-te-1 ""ilor V ~(J~O.,) a dl-;-
at min. K~Jvc 1) [fl jr 'I'llre
V M. lot'. VO Olleited Ight-j with Nco V W'1
se~kd tilt.!, thc alowit "bu.
resitille i;i I
pyrfitine. a-Ill tilt! ~oln. let itar"I ~ev:,!:~; .1"
g. DL-peo iCilla mine, XtIC(SH)CM '- H, r'. I
rdtvoinpn~),
givinj with 4.,
(vich,in-sc, --d P~::
I. cQl.,)r, which cirt tur;
anti lvitl; FeCi'a blue color. The deacetylatiun ,! V,,,. 11
not be effLeted, by heating I fir. with -".V N:O~ii o!: I
water bath. 11 (I.M) g.) treated with c!)oliv,- v~'il ,j i~'
aic. N NaSH, and tile inixt. let stand ovcntig,!~r
1.44 it. Ma s4J1 (Mof IV, taicrocry-it- i hoinbohei!ro% r,--%
it bol. fit 1110 with neutraA reaction; the P:I. 2oll. gaN c.- YJ
y
Pb(OAc), a brown color and on boilinx a black ppt,, ;viih
It C1, a pate 3T',IGVV ppt, which turneit snow-white in ii fc--
win and with FeCl, a tran~iuut brwmii~h color. '11:1,
tnot~er lititior front IX tvapd. to dtN-noss in ruc:w, t4e:~i,.
phoug pale vclto;v resiclue (1.8 g.) acidified with 5.5 te. 2..--.~,
niass d1s5olvLd in EtCjAc, tiiu
TICI, the resulting sticky .
EtOAc evapd., and the reiidual g-unimy prrxluct (O-q g.)
treated with 3 cc. MeiCO and sotne H:O, and let suad about
I week yielded 0.32 g. III, pale letrion-vellow p1litei. "i
1 12 3"; i -d amt.,
Eli, moth-r liquorg. VI (0.1 ,4 !1-~;!
sublimed without. residue to give 1 1, -1 ~-"e
-Z. P.,
lemon-yeltriw crystali, til. 143'. V1 k slightly III0.
sol. in MelCO, or MOAc. imol. in Nat'
IC04, sol. with p:,,r-j
11 decompn. fit aq. NaOll. VI (0.05 g.) In 2 cc. EtOAc; 0
"Iat!d. with I ce,'O.ON art. N4iCO3. anti tile ext. evapd' gave I/
0.05 g. oil which socin cryjtd.; tilt-. crystals di;iAvvil fit 2 cc.'
EtOAc, exid. with I cc. lee-cold N NaOll, and the yellow;
ext. acidirlegi with I cc. X IICI ppill. only 0.01 reccivf:rcd~
q' -n
4
~L Pf-i

OF
2 0 17-101V 111='O 414,0 1
V4 til. V1 gave With 144 nitropru,"Ide In dif. arl.1
I,,
a dtp vlo!nt. it, lig. NaXof a pink ct)for,aud, wheni
U!~Af,A ill alk. anla., filaolvWed aq. Pb(Ojkc~; it reduced,
l7ehl!'Ig "Oln" and gave a ppt. with tfgcl,. 11 (13.9 g.) In Z3
CC. ` r1A. MOR trtated with cooling with r, cc. aba. ate, 2.31V
KS,!I ar.A the inixt. let Qtand overaight depoitted 17 g, K
i,:11 (X) of Al crystg. with 0.5 mole Etolf, fine, stout, white
prl,m3, rea-Ely col. In H,O; the cold eq. soln. did not q
. ive a
ppt. of- Color, with 11b(OAr)j, but pptd. large ainti. (if PbS
on boiling; I' 11d not give Ali instantaverm3 color with Na
idtroprus~,tde fit neutral or alk. -oln., but gave tile other
Color rcactiorm and T. pt%. given by IX. 11 (13.0 g.) In 23 cc.
dry C,1-1, tmated with 16.5 cc. Et,NT, H~S pas-;cf during sev-
eral hrs. with coaling into the mixt. to a wt. increase of 0.9 K.,
tile UliTt. let itand 610 hri.; and (lie ppt. wambed with it,
C,
yielded 6.8 R. Filly Ol (Xl) of TV, in. 90.P, sol. Ill fj,O
with ne"tral reaction; In alk. r-oln, with Nra nitruprus5ide It
gave no coloration but de~eloptd a blue calor in
about 10-20 cc,; tho at-her color reactioas and ppts. were
""It" to thc1fle Of M. IX ',1 12 9.) in 2 cc. 11j0 treated
with with 2.05 cr L.i5N IICI, flit mi~xt. let stan(I 2
.Gild t!!.-. ppt. Witil i,e-lld If,O and (tried at I
rmr- r-'rid rcmm teml). Over li.,So, vivilled 0.85 g. IV, in.
IOU-W. gi"nf With rle,03 a transieiit brownish violet
,~cbx. with AgN(,), a b(htc,& and %vith I-igCI3 a white ppt..
,,=d 1~~&-tnjng a hot alk. Ph ialt bola. IV (0 ~25 g.) trl-
t=21,-d 10 inift. with I cc. H,O at 'M-80', the heavy color.
I~Isai ed coo!~-d. and the resulting solid filtered off and driell
91-1~e one in.
3P. IX (0-~O 9.) in 0.9 cc. H,0 treated with 0. 1 cc. cormi.
HC1, the pptd; OU Woled, and tile resulting crystah filtered;
'Off Uffed With Ice-cold 11.0, and dried at 0.1 ntrn. gave,
x1i 17M. 34.8-85*; the M-r,- ro,~e after borne weeks to 42';'
RU 13 SO). in MeOH Phil gave with Na nitroprusside Lind'
dil. aq.
laollikPLIkorredicolor. X(1O,5X.)frf6OcC.
I cohl 110 frtair'yi wftli 'r) (v IC! r~,j
SQ!VLd in ite-Cold E
Ice-cold 0.6X Nallco" drw'!
and the reqfdwd oil dktd- ;,,:!
37-8'; the eq. Naffc(), wahirij
JJCJ aurl ex-td. with PLOX m
filtrate from the addill. XII 1-1 't t
, , , KIT
apin with MOAr ptv( un :L~t(ltd
that tile soln. cmitaimf f:u,: IV F:1-
freiii X1 wTsh.,A -,vilh 46 ce. w--H 2
with 45 cc. Ice-cold 2N I h, 1, i
fi,d with IM. the pAc,,UIor-i. 'tivk. !-,-,,t
EtOAc, the soln. dried with N ro 1;
r3cuo, and the rt-Adlit, (9,15 g, "t
ith col, r cr.
ttituratrd w. _i FtlO yi,!ld d 1: g, V.
tals, m, 99', gNing Y;ifli FcCl, :t hromikh rcd -Wil ~`A
nitropru5sidc in aq. NalO.), t furhAn-ref] Jil
NaOH a deep bluish violet color, ind. %Vhts ho;,M
Pb(OAc),. ablackpPt-' VO fxi-~,, 5 cc. %1~01`f i"'
HiO treated with 75 cc o M.lf ml FAA, ill :iniall iwi,
A,, 1, hm,-ntAi m, c '-,,i
(each 1lortion gave a traw~ipni,
and the cryst. lipt. filtercd (01 m,-! -~sl:vt wirl! , we-I'A
H20 yielded 0.72 g, V1. pale ri. 14(~-;';
the mother liquf)r,3 cxtd. with I-roAc gn%r '111 addill- () ZA z
V1, in. 142-3*. 1 (7..j,,3 g ) hem-4 15 min. it aL-mxt 7-
with 15 cc, artlis-d. 11C0,11. th, li,"04i drAd. -6 i~ 4---: w-.
the residue again tieAteu witli ~t. HCO-H, ,
FICOJI dMil. off, tim re5irl- -d '2~1 min -ith 15 c,
Ac.0 on *Ji,2 water bath, in 4~ 1cli 1--A $;,v,:
K.
art,:r r-moval of tht:
exazolin-5-One (XIII), b's 82'. 5GjjE!ifi,-d and ill. abelit 01-t
X111 (0. 11 g.) in i)~5 cC. %fe,C0 vently ivmned rwith W5 CC.'
11,0 until clear anti the ulixt. i,-t -,tana sevrral brs- dr-
in
Poslt&j 0,06 9, AfriC.-QN11OCWCV1, fille crYst",6l
18"0 (decompn.). I? W. Houtmaurt i
.2

AW~Pfi'~~
p pf
-t--
Mv

=20.
-ig

/Z) rA
__C hol 4S.
W!"th of %C; 0
fiuloffla!y);
rim dehydration t'!agent, W,,~
changed I%CH(0IQCIfxR ',I) to n6mit 37~,~ PhCH:C111,
(4) and mall yields of 1pb(0ffR)CJj)jO (111). ALS3111g
m g. Sol Into I kc. I (R - Me), letting (lit mitt. Suild
ovtrnf&ht. and disq. yielded KI g. oJortcas distillate, frora
'ghlch 110sul. Ift0sepd..and yielded' 56
It (R - Me), b,. Vq-71 1. da 0.913, ond 43 g. h -I I
R"t- Afe), bq 103-7*� 111 reinained as
"Wn., b. atxmt kil". Simil.ir results were
~
front I (R - Ft or Pr). Yields uvre reverscif A
Ph.C11,011 (IV) was sinkilarly ttcatcA with 67 g, Kh.
1st distillate yielded 21.6 g. unchanjzi,~l IV, whem.1'. thc 1.10 1.
yellow oily residue yielded 'jO g. (PhCHI)ip (V), W's 1:14-
._40", bm 207-8% d., 1,020. and 16 g. (probably) PhCffr-
OCf1&Ctff4CH,P11. bo.t ]g&-210'. (fit 1.078. The much"t-
nisim of thm reactions and steric prOActm relaticd to
H (R 17 Me~. and lLq addn. compd,. with Dr mad Yvith
PhSO~ BrMe (C-4. 25, 637) are discussed. Both di-
mistertioulers of PhCUDrC!lBrNit(VlfttttdVIb)tvcreprep4l.
by the slow achIn of 16 kg. Br in 3.5 1. CC4 to 2 kg. ice-cold
H (R - Me) In 3 i. C", "moval of CCI, in mev o. and ctyst n .
of the residue from 1 .8 1 - pctr. ether to yield 3.59 kg. Vla. in.
0414". and 899 X. nily Vib, 1), aiNnit 120-5'. To comra~t
-the thermostability cif the C-0-C band In e0wri %vith
__tbsja%tabj9q.O, the shnilar Wnd Inawali. If( (it - Xf~).

PhCIIjOCII(F0Phjs (IX), PhCII(oDCIIiPb)%
and PI)CH(OCILCH'I'll), (XI) were synthe4zell. CatRlylic
retloctin" I rd~jlaSO.)) of ~,4-(MeOlsCilLCHO yit-ldcql 12%
Vll,m72-3.5.b.315-24 btratmuo!TW. EtNfgDtvvlth
3A-CI4jOor-,If4CII0 yiel&d 10-vi-H, Vill. I.,
Ifeating I I it. PhCH(OEt~ and 30 S. I (R - Me) 30 tilla.
In an oil bath at 140-50", distg. off 4.6 g. FtOlf, fraction-
Vting lite residumt oil in rarila. n1i'l redistz. tit atin. PresNure
F-.%ve a mixt. of Brit, It (R - Mc), I (K - Me). b. tip to
17.3 g. Ut (11 - Me), 1). b, lq"*, d.
t
o
01991. Adding 10.1 g. PhCHO, to) 100 g. I (it - Me) with
which 5 g. Na load reacted, letting the rnixt. stand overnight,
Itcatitig several lots. nit a If:O bath. adding Colloo and lIsO to
the cx)lcd inixt., Mitil, WT the sottvent from the rorg. layer,
and fractition-sting the rvildivil -i1 in meno yielded 73 K, un-
-changed I (R - Mc) and 13 g. IX, 146-56", do
1.041, MiCH: NIlPli (18.1 g.), CO g. 100' 'c IISOj,oknd 23
g. IV were allmytit to stanil ceveral dals In ether, filtem4,
wa.,hed irith petor. ether, anti the NAvent ofistd. off to Itive
24 g. oil, twice fractionated ift mcua to yield 7 C. X, N-i
about 168*. A similar procedure with mcnicif,ok in
IV yieltled 2r,'!'g XI, lu.m K6-80'. The ethers (VU.
var a"'d 111) distd. without derompo., whereas the aLetalti
(IX-XI) vvhcn distd. at attn. pressure decompol. Into Brit,
11, and the parent castoinot,pr into IV, U. and the'ketone

tillu. rif tilt-,
Ml from M5 K. IX gave mil A
B (24,t g.). bo 100-2W. A wai
;()4 WId yi, ldvd
rr liija with 101"~ Nul Is
129 g. 11 (It --i Ate), b. 1M4101 do ORA which giivc Via
31 g. 11 (it - Afe) and 191 C. I (it - INIC). b"% IW-I'. tl~.
trace Gf DzUt. NI.A. modds show the rigid
cetalsascampared With the case Urrutation
of the ethers ~111.10.-the C-0-C UW to this dif-
ference is a3cribed the decompa. of the acetals witnin the
"ne tcmp. range (280~120*) in which the cilitrs diald mi-
decompd. Ily-oluct.4 during this investigation Wert the
W-act(al PhCIj(Ojl)OCIlPt-rh, N.wo 111-W 114.5
from 11 g. Ball. 30 g. 11 (R - Ate), and 5 g, 100~1,, Awl
the bromo acetal PhCH(OCIIPhCIfBr%fe), (25.3 g. from*
6.7 C. DzH and 21.5 g. MeCiMCIM011) (tfx) unstable
for purification); and the ether MeCtIllrCHMONfe, N.,
WS' [100 g. (crude) from 300 r. V1, OW ml. AlcOlls and
jul. coned.

14. svathells of Alphis-OKO-beta-lic I-ramma-butm-
V, lactods defivallves l"li'a
1955 NO-
*111171mae 1 ~14955,
3-4, pi)._101-32L.._.-
Tit the coutse of earlier experiments carried out
with the object to sysithesizc tile compound patullti.
Its istimeric compottild was ubtaiticil Instead. Th6 vrork
ww~, mitivrtak-en to establish the litmitioll of the bromine
sitom Ili the molecule of the ittonobromo derivative of
t1l(* imillicric vollillottild. The collilmillid alphn-ozo-lieta.
wits selctAcd m a 11100.1ci
substance for this purpose awl ylelded. upon brottlination
n Ili) lit -oxi)-heta-bromo-acet %,I -butyrolactusic. Tlds pro-
ilkict reacte.1 %vith pyridi;ic or quincilinc by forming
1111stntile salts or 6!taiii-like coitilmosids and thlazall:
'let ivativ ch w e r eptod%mcd by as hiteractiort with
t11101iff.-A Ot SU1101111illyl thlOUICIV. The itiontibrottio cont.
1ximid was'hallsfolumil Into through
tile ;lCtIoll Of fit aCCtOjje SOlUtIOll.
Starting from thii monobrouto derivative a three-
11 CMIK-fell condensvil H119 System of a flew tylv - Identl-
ied ai a furn-thlazolo-pyrall --- was preparcd. The
Beckmann-rearrangesitent of tile NO-patuffil oxiglic
yielded a jittv tylx- two-sitembered condensed rhig
3ystem which was idesitifitil as an oxazepofuran deriv-
litive.

FIDIZI, Zoltan Hungary
Ueber aryl-Alkvl-Carbimle --- Festigkeit von C-0-C Bindungen
SO: Chemische Technik, March 1956, Uncl.
M NI-2 5-17-

1 71. -1 , - . , , - - ! . - *14 '. ; - f ~ ki " I i - ~ 4 . ~, '~ , ~ ; ~ z - , , - , ; "
7 i
. * . I

1d,
4-Myl oxazolidines. Z. Foldl.
I fit nFnYS,_1 VRffFii+
ditneth~xyphenyl)oxazolidincs were
(aq. McOlf); 2-(4-ni
(aq Alcoll ; 2-(2-hydroxyp
131-methoxy-4-hy
(Et
r, Iow'\ tn. ?6111_1 150 (StOl 1); 2-0.4.
A~_
Acta Chim. Arad. Sci,' :over P to const. wt. to yield 228.5 Mg. orange cont
-The [Wowing &(3 4-' CoIfu0sNJf,.SnCI,, m. 106-200'; The tetrachlornstanalte;
prepd.: 2-phenyt (i), of XVM (116.8mr.) was prepd. by adding 113.1 mg. SnCI'..j
~21W In 0.2 mt. coned. HCI. allowing to stand Overnight,,
thoqRh
in a Mp. tat
adding a further 0.25 mt. of 2M SnCIj solo. t
i a(4
133.5-3,1* (1:2 ClICIM
".brownish yellow, in. 107' (nq. Ht0fI
tit. 154* (8!3 betizene-CIICI.:
VHI).~b, 160-6'-, 2,2-(I-carbeth'
'in, 133-4" (benzene); 2-met4l.2~?!
tll~ .104.5* (0-1 11%0-McOll ; 2.
'(paie yellow), m. 140* (WIT). Al
~'.,dlnes were lid.: dl-24~;n trophen
------
m
HCI, and drylog 14
'~X, washln&with 0.1 ml. coned 140.
n 1) mg., m._23"* (decompg. to a black man).
4 mi. hot abs, Wit with SN abs. C-thanotle HCI plus 10
abs ether gave it yellow milt. which was filtered to yield 3 g.
a* 'MI1.11M. in. 1641. When 112.6 mg. I In I ml. &r
Ut sbenitene-was said. -with dry HCI. an orange-yellow man
(162.1 mg.) was obtained which on drying over PA at 0.1
(K.
sulted In a wt. lost and decrease In C1 content. from
xt tnm. re
Infl-, 25.6 to 18.00% after 3 days; CjjHjj03N,3HCl requires
20.96%, Ct, CnH,*0jN.2HCI requires 19M%. A beriloate;
MY
at I was prepti. by adding 1.5 S. BzC1 In 8 m!. of Clach,
pottlonwise to 2.8 C. I In 5 rid. of CHCIs and 7.5 ad. ISM:
yellow oil from benzent- dl-2-(2-h drosyphenyl)-3,4-
du
th
l (XIV
5- 3
03
f
l
4 NOW Petr. ether was added and the CHCIj layer sepA.
.
ne
-3.
), tit,
.
f-2-pheny
; i
y
42-6*
'dinictityl (XV)
1-2-
b
t-3
44.
1404% m
litn overtilghttoyltid 2.0g. solid. This was recrystd. Irmn
l
,
b
ld
1
.
o-%
,
y
,
;
p
m. 6"V (10:1.6 M011-11,0), WV-
7
* 37-
entoate m
to yie
2 g. mono
A
1 diben oat pd b the method of KInJIer jC.A.
z ew e
;
:'_
Vll

1~45.27
7.5, abs. EtOli), di-2-(3-methoxy4-hydroxy
(c -
378-5), M. Kindler reported 141-)-
-
~
(XVIP, in. 141.5* (benzene-petr.1 methylation of XV with clWiandmethin IcNaOrjoni
I was prepd. from 23.3 g. of 1-(3,4-dimethoxy-
ether).
water bath for 20 toln., XV was recovered unclippired
ipheityl)-2-nminoctlianol-HO (XV111.11CI) in 20 mt, HjO Reduction of 18.8 C. I In 60 ml. EtOH was carried out with
with 8 ml. 40% NaOlf and It g. BzH. After standin 4
'
U .0,25 g. PdCl, on 2.5 g. pptd. BaSO4 at room temp. and
*
hts.
a thick oil sepd. which was washed with H.0 and d -usual pressure In about 40 win. The mixt. was filtered aW'
oitt room temp. at 0.1 mm, to const, wt. to yUld 28 2
I
etude) 1, tn. 9(~-I* (aq.44;G11). II, IV, V. V1, V11
& e 15.3 C. 1.(3.4-dimethoxVphenyl)-2-benz)i-.;

' Aln
=tW(4v IX
870 (2:3 c0H-'H
m
0)

X, and X1 were prcpd. in a similar manner froin .
.
j
,
ethanolic sol
701 1
o
n
k1
1k
t
d
t
M

'11C1 and the corresponding aldchyde at ketone
Ul wit 1
n.
ro
wits wea
.
atto an
o
s
y n
9
5*
lk
ith
170
dd
f n
Th
XIX
HCI
o
. a
. w
a
it. o
.
in.
.
.
e
j
0
I

l
jpd. ftorn XVIII Rod mlicylaldchyde. X11, XM'
XM dibenroate m. 135.5* (MtOll). Reduction of 7.7 g. Min;
V
i
XVI, XVII were prepti. from the appropiate ephetirtne,
TICI and free base, resp. The tticlitorostqnnite of I was 177 mt. want EtOR Witt, 0 g. p Cl
'Z d S Ott C (or about 65 M
I pve 5
1 1-(3
'I~imino
4-dimetlioxy
liciiyl~2-(t)~
tnis
prLpd. by afItIn. of I itil. of a 2Af soln. of SnCle In coned. .
,
,
p
)
11-
ethanol m. III.P. depressed on mixt
.
with
lJC1 th 14'.5 nig. I to ppt. yellow crystals which werei .
.
.
washed with concil - IICL drieff over 144011 at 0.1 nitti., and

XX.1ICI in. 20-1.5* (expanding to an intense yellow melt).
I Reduction of 10 g. XI in 100 ml. HtO11 with 0. 15 g. PdCls on
1.5 S. C for about 40 min. followed by treatment with
~,EtOIWICI gave 7.0 g. orange I-(3,4-dhnethoxyphcnyI~2--
1(4-fimiiiobentylaniiiio)etliatitit-211CI (XXI.211CI), softening
if%tl47*. Treatment of 7 g. III In 70 mi. Molt with 0.08 g.
PdCl: on C with ff at usual pressure and room temp. for
about 410 tifla. gave after treatment with abs. ethatiolic IICI
,a 1g.XVIII.JICI,m.I6V. III(IOg.)in75
nd abs. etherOM
nil. OAN NaOll and 60 mi. HtOlf was tre-tted with 0.15 g.
PdCl, on C as before for about 40 min. and the mitt. neu-
tHized with coned. IICI, filtered, and dried in memo.
'The product was treated with ELOH to remove NaCl but
' 1-(~.4-dimciJioxyplienyl)-2-(2-hydroxybetizytamino)rtlianol-
i TICI could not be obtained In cryst. form. Reduction of
10 g. IV in 130 ml. BtO11 with 0.11S g. PdCli on C for 140
in,
min, gave 10.1 g. product whkh save on treatment with
C',
ethanolic 11C1 4.4 g. 1-(3,4-ditnettioxyplienyt)-2-(3-ttieth-
~Oy(411tydr6xybLnzylamino)etitanot-liCI (XXU.HCI) with.
ox,
1. .1 .4 meth4 henyl)-2- (3 -met hoxy - 4 - hydroxyben zy
mino)ct an
h c 91. The Intter compd. was a hydrate, in.
20'. then above 220'; its free base was obtaincti as
listening finc rent
intedits front dil. H(Oll, in. 107*. T -
cut of 10 g. III as above, except in 100 nil. OMN MOM
th 0,16 g. PdCl, on C for about 70 min. followed by HCl
~~"veg.2g.XXII.IICI.ln.177*(abs.EtOH), ReductionCA
ak
7717
ambuiethanal (1=1), in, 82-30 (aq: it I gait, in.
182*. Reduction of 6 g. V1 In ethanoMtb),011C2 1r. PdCI0
onC for I30m1n.pva5.8g.oI roduct, which was dissalyed
in 411. IICI, extd. with ether. teen made alk. An oil $Md.
which crystd. on standing. On recrystn. from aq. mCcill,
2.0 g. .1-(3,4-dimethoxyphenyl)-2-tttrylaminoethanoI was
obtained. in. 00'. Reduction of 5 g. VU in 60 ml. EtOH
with 0.075 s. PdClj on C for 170 min. gave on evapn. 4.8 1.
bright rose powder. Addn. to' ethanolic HC1 gave 3.8 S.
1-(3,4-flimethoxyphenyl)-2- (3-pheitylpropylamino)ethanoi.!-.
HCI, in. 172-3*; free base, in. 100-l. Reductianof3.1 ji
V111 yielded 2.2 g. 1-(3.4-dimetboxypheuyl)-~Tlohexyl-
aminoethanol, in. 94--4.5*. 2.5-Diplienyloxazollifines such
as I and V1 are considered to be In a dynamic it. with the
I
Schiff base or luilnoethanol stnicture but G1, IX; and
oxazolidines of the ephedrine and pstudoephedrine se '
axe
considered to be chiefly the oxazolidine. In a .. r'es
IA. like
XV the N-niethyl and 2-phenyl groups are p hably trans,
from steric considerations. In the case of rVDM and IX,
where the 5- and 0-membered rings exist u a opiro Itakap
6 boat and 2 chair (omw yield possible
84- and 84 I=,
However, In the crelollexV. ring, mterle requirements of the
N-11 and especial y the -Mc group. n permit only 3
boat forms atid Oita chair form (equatorial, D.W-r-
Z. V In 450 rrl. warm EtOll with 0.15 g. PdCIj on C for
save 5.3 ff. 1-(3.4-dituethoxyphenyl)-2-plpemu*.

HUNGARY/Organic Chemistry. Naturally Occurring Substances
and Their Synthetic Analogs. G-3
Abs Jour: Ref Zhur-Khim., No 13, 1958, 43495.
Author Foldi T., Foldi A.
Inst Hungarian Academy of Sciences.
Title Confcrration of Psi-Ephedrine; Copper Chelates
of 2-Amino-Alcohols.
Orig Pub: Acta chira. Acad. sci. hung., 1957 -4,
339-348. 11, No 3
Abstract: In connection with elucidation of the question concerning
the presence of an intramolecular hydrogen bond in Psi-
ep~edrine (Psi-I) and ephedrine (1), a study was made
of copper chelates of .1, Psi-I, and other 2-amino-
alcohols. It is shown that (+)-Psi-I forras a copper
chelate MP 209-2100 (decomposes;
Card lAr
o;_2

HUNGARY/Organic Chemistry., Naturally Occurring Substances
and Their Synthetic Analogs. G-3
Abs Jour: Ref Zhur-Khim-, No 13, 1958, 43495.
from CHZOH), insoluble in water and nost organic
solvents, soluble in alcohols, and containing (like
the other investigated Cu-complexes) two molecules
of amino-alcohol per atom of C!u (II). Under the
same conditions th re is formed from (+)-I a chelate
hydrate mp 165 0 (decomposiT07 Dy the
action of- cold a7cetone (I )-III is converted to the
complex (:t)-iv, mp 169-1710 (decomposes) (see pre-
liminary couronication, PZhKhim, 1956, 65o67). For
(� )-III ther is known a solvate with one molecule
of %11~, 14P 157-1580 (decoraposes), soluble in organic
solvents. The authors note that the data obtained
are somewhat in conflict with the assumption (Fodor
G. et al., J. Organ. Chem., 1949, 337), that intra-
Card 2/(,

HUNGARY/organic Chemistry. Naturally Occurring Substances and
Their Synthetic Analogs. G-3
Abs Jour: Ref Zhur-Khim., No 13, 1958, 43495.
molecular hydrogen bond is possible only in Psi-I,
but not in I. The assumption is made that, probably,
CuII -- a sTrong coraplexdr, impels internal com-
plexing of I notwithstanding the spatial hindrance.
This is confirmed by lesser stability of (t )-III
and (!')-IV in comparison with (+)-Psi-II. ( �-)-IV
decomposes in organic solvents, 4 11 aqueous solution
of WHZ, in solutions of allmli tartrates, in aqueous
solutlon of (NH~),LS, in which (+)-Psi-II is not
decomposed or is decomposed core slowly. Psi-I
reactd with CuSO4.more rapidly than I, since on
interaction of a mixture of (:t)-Psi_-I and (� )-I
vith an insufficient anount of CuSO~.there is formed
(f)-psi-ii, mp 2o6-2070. The authors note that by
Card 3/4
54

IIWIGARY/Oreanic Chemistry. Naturally Occurring Substances
and Their Synthetic Analogs. G-3
Abs Jour: Ref Zhur-Xhim., No 13, 1958, 43495-
means of Cu-coriplexes it is possible to separate
also other diastereo-isoneric 2-amino-alcohols.
Thus, threo- 2-amino-l-(p-nitrophenyl) -pro-
pandiol-1,3 3thrIe_o-(�)-v
I forms a complex, mp
153-1540 (decomposes), of the type (+)-Psi-II,
while erythro-(:t )-V forms an ionic complex, MP
123-123-50' (decopposes), of the type of (�)-III
without water of crystallization). From threo-
*)-V was obtained a complex of the type (+)-Psi-
~
II with two molecules of water of crystallization,
MP 133-1340 (decomposes), which on treatment with
CH7.OH is converted to the more stable, anhydrous,
triins-form, mr 162-1631 (decomposes). moreover,
from threo- (+)-V there was obtained a complex of
Card 4/6

Humm/Organic Chemistry. Naturally Occurring Substances
and Their Synthetic Analogs. 0-3
Abs Jour: Ref Zhur-Xhim., No 13, 1958, 43495.
MP 2701. It is shown that 2-amino-alcohols with a
tertiary amino-group also form Cu-complexes, for
example, a Cu-complex of type (+)-Psi-II fror.1 (� )_
N-methyl-ephedrine, MP 176-1770 (decomposes). It
was found that anino-alcohols with a primary amino-
group forra insoluble copplexes only if at the C-
atom linked to the OH-group are present bulky sub-
stituents da-complex of dimethyl ether of (t-) 0
-noradrenalin, of the ( r)-iii type, mp 165-166.5
(decomposesg . Mhanolamine (VI) forms with CuSO~
only a colored solution; benzal-ethanoludne does
not react at all (a partial coloration uf the solu-
tion is due to hydrolysis to VI). No reaction what-
ever takes place with 2-phenyl-5-(3',4'-diL-ethoxy-
Card 5/6
55

HUNGARY/Organic Chenistry. Naturally Occurring Substances
and Their Synthetic Analoes. G-3
Abs Jour: Ref Zhur-Ehim., No 13, 1958, 43495-
phenyl)-oxazolidine and 3-araino-alcohols, for example,
2-r,ethyl-4-aLiino-5-(hydrcocymthyl)-pyriiaidine, tropine
and Psi-nortropine. It is shown that 3 moleculeB of
(�)-Psi-I form a complex with COII(CoC12.), -which does
not melt up to 270". All the investigated coqplexes
,,S with liberation of the corres-
are decomposed by 11
ponding amino-alcoliol. (+)-Psi-II is obtained on
grinding 1.65 g (+)-I with 10 ml water and 1.25 g
CUSOI.5W, adding 10 al 1 N NaOH, and separating
the resifting product after 2 hours; yield qq~-
Card 6/6

Distri _ Wq_(~)/Wd
?1~0. Addition of
hydrogen sulphide to the altrile group
~
j of A!Iflulghonyl gJ404MIdellby Mexas of thlos"I hqqc
Re , A. F91di.
'4 In. jCin IF 5 T. Foldl
WICOO. V'01.
eta Iffing
13, 1067, No. 1-4, 111-116
A new reaction Is described In the course of which
free t4losulphadc acid Is added to the CN group of aryl-
sulphonyl cyanamides whereby very favourable yields
of aryls honyl thlouim (Orm. The known decompoel-
tion of "Mosulphuric acid into sulphurous acid and cle.
mentary sulphur could be LVInpletely te Fo=, I Iby the
iuldition, of sulphurous add to the react on inixture at
the start. The properties of acetyl sulphanily) cyanamide
and sulphanityl cyanaudde are discussised and the a
new reaction mechanism pmeented.

L
Diatis
'46lia'n-pa-d EI&M,
.'A novel reactlon of dinei.
kern. & M. I Lou on)TM
____W_orkp, Budapest, Hung. . M
wt-bi-Benteutsulkayl chloride (1) and X~nxthylephed
rine (11) wen mixed in dry Cj4N or -r-MCAN and the'
ACI salt of II'pptd. From the filtrate was obialned I-
yi)-l-benzemejulfoxylethaxe (111), m. 107*, Et4N
antraW, gave Et&N.HCI end IU; I and -1-MeWIAN gave
J-(T-YriJYJ)-I-6eI "S%4V4QXyIMdA4Ne, M. 201.6% -t-Et-
C&H4 and p-toluenesulfonyl chloride gave
(P-tolue"esul oxyl)dkaxe, m. 143.5'. The structui es of the
AM Wonyl compils. w!re proved by direct Synthesis.
T lat an alkyl
h4 riaction 13 novel In ti pyridine acts as a,
Proton donor and und C-arylsulfonation without tim:
Unce of a catalyst, he Mzenesuffonyl rup augrating I
su~stituent. Af H. Ramsd=

C ount ry : Hungary G G-3
Gatceory : Orraxdo Olwnistry, Nattiral ampounds and their
Synth,9tio Analogues.
Abs. Jour. : Rer. Zhur,.-2tidiya No. 6, 1959 19592
Au4t"ho r : Foldi Z - Foldit T.; Foldi, A.
In3titUt. :iiu:~ ~Nr U Academy of 8ciences
Titlo : Chelates and Conformation of Cinchona Bases.
Or13 .Pub. ; Acta chim. Acad. sclent, hung. 1958, 16
No 29 185-192
Abstract : Confirmation of the previously determined con-
figurative relationship between quinine Mt quin-ldine (H),
cinchonine (III) , cinchonidine (IV), and ephedrine M , and
the relationship between epi-I, epi-II, epi-III, epi-rV and
V -V, on the basis of data concerning the formation by the
above-stated alkaluids of chelate compounds (ChO with Cu2+.
I-IV do not form ChC and are configuratively related to V,
epi-I - epi-IV form ChC and have a configuration analogous
to that of Y -V, The capacity of forming ChC and hindered
rotation about the C(s) - Cp)elinkage in the epi-bases
suggest the assumption'of t a xistence of a rigid hydrogen
bridge -0-H---N 4- and therefore of the existence of a five-
Card:

Country Hungary G-3
Catogjry=
Abs, Jour. 19592
Aut'-or
Ins't"itilt,
Titlo
Orig. Pub.
Abstract :membered ring which constitutes an.additional
isymmetry in epi-I - epI-IV (N atom -- new center of symmetry)
Ls compared with I - IV. Capacity of f orming ChC in the case
3f epi-I - epi-IV :Lndica-'%-,-es apparently that corLtiguration of
juinuelidine ring, in the epi-se-ries is represented by the
rormula A. This shift in the quinuclidine ring approximates
~he OH at C(q to C c)) and renders possible the formation in
Lso-quinidiiN and iso-cinchonines of a new seven-membered
ring by the action of acidic agents. 0.648-g epi-II are
around in a mortar with 5 ml 0.2 M solution of CuSO4, 2 ml of
L N NaOH are added, after 2 hours there is filtered off a
Card: 2/5

Country Hungary
GatcSory
Aba. Jour.
Author
Inutitut.
Title
I
Orig*Pubo
Abstract
H
C--rd:3/5
G-3
19592
8
N
8~IN
H
epi-I 0 epi-TI A
H C9 atom is linked to residue of 6-methoxy-
quinoline

Country :Hungary G-3
CLtosory=
Aba, Jour. 19502
Aut'ao r
Institate
~Titlc
I.Orls. Pub.
Abstract :ChC of composition (C20H2302N2)CU 1-5H20~
yield 0.? g, decomposition point 150-1900. Analogously from
ep-1-1 was obtained ChC of epi-1, decomposition point 160-180
and from the dihydrochloride of the double salt epi-I-epi-II
the mixed ChC of epi-l-epi-II, MP 125-1600 (decomposes).
0.61+8 g I are ground for 1+0 minutes with 20 ml 0.1 N AgN03,
after 10 minutes (600)-there is obtained a molecular
compound of COMPOSitiOn C2,F-2,N202-AgNO3-2H20, yield 0.94 g,
decomposition point 202-2050; Epi-II forms-an analogous
compoundq MP 1800 (decompos s). 0.648 g I are ground with
20 ml 0,1 N AgNO3 at 200t then 10 minutes at 700, after
Card: 1+/5

C~juntry IIIIngary
Catogory
Abs, Jour.
G-3
19592
Author
Institut.
Titlo
OrIg"Pub.
91a
Abstrfact I hour added 2.1 ml I N NaOR and after 5 hours
there are obta:~nid 0.882 g ChC of composition C2GH2-N2202A9'
-H201 MP 10"510. Bpi-II yields under analogous condition's' a
ChC of decomposition point 170-1800. Epi-II, dibenzoyl-d-
tartrates of epi-II and epi-I give a violet coloration with
solution of CuSO4 in NH,OH and C4HO.H. Preliminary communi-
cation see RZN3,,,im, 19572 71+559. -_ ke. Tsvetkov.
Card: 5/5

26160 A Nova "aadon of &~~M~asc (In English) Z.
~Ylll,dL,Atft Maim AcadMIN-BiWoruft Hungaria",
(414)
Vol. AV. loaf. X0.1-3, pp. too-Ile
A now reaction w" found secordinit to which idkyl'
pyridines (s.e.y. railbylpirldlao) with aryl sulph4nyl
chlorides (#4. bonzenesulomyi chloride, p4myl ohlorWo)
give faWylloldd of 0-aryl sulphonyl derivatives under mild
conditions without As use of catalysts. The aryleulphonyU
group Is linked to the a-pooltionad 0 atom of the side chain.
The position of this bond, was loved by independent syniho.;'
I
;so* of the new comi3ounds. PA series of new oompounds~
Is &-scribed. #.g. I.Dwmnaaulpbmyl-l.(,y-pyridyl)-athe";
Am.p. lOrC).-I-tp.twyl)-I.(rpyridyl).odiaiw(m.p. 14100),'
~-y-(bousenasulphonyl.wAthyl)-pyridine (rh.p. 20110), a-snainb-,
j.-y-athylpyritline (m.p. 66--70",C) do. It was found moreover
-that, In the course of a side ro"tion, 4ryl sulphonyl oblorWas
inre CAPAW of clinavint the O"Wifto Ads Whus Coloured glu.,
Aialldshyda r1v*Uva4 an formed, I
tooorm A (am,
14 Presented for the Interprotsillon of the inlifrallon of the,
The
arybulphollyl poup from the n(trow Maus (I.@. from
!primary of Attack) to am side ehwn.

ERDEY-GRUZ, Tibor, akademikus (Budapest)l CHOLNOKY, Laszlo,, SZABO, Zoltan;
SZEKER, Gyula, kandidatus; _FOLDI,_ Zqjtan: LANGYEL, Sandor, a tudamnyok
doktora; TAKES, Pal, kandidatus
An account of the 1960 vork of the Section of Chemieal Sciences,
Hungarian Academy of Sciences. Kem tud kozl MTA 15 no.4:401-460 161.
1. Osztalytitkar, Magyar Tudomanyos Akademia Kemiai Tudomanyok Osatalya,
Budapest e-9 Szerkeszto, Magyar Tudomanyoa Akademia Kemial Tudomanyok
Osztalyanak Kozlemenyei(for Xrdey~-Gruz) 2.Lev.tag,(Magyar Tudomanyon
Akademia. Kemiai Tudomanyok Oaztalyanak Kozlemenyei for Cholnoky, Szabo,
Foldi.) 3.Szerkesztobizottsagi tag, Magyar Tudomanyos Akademia Kemiai
Tudomanyok Osztalyanak Kozlemenyei(for Lengyel)
(Hungarian Academy of Sciences) (Hungary-Chemistry)

FQljDl,141t&m-, dr. (Budapest IV., Ujpest To u. 1-5); aIDT-LAXII, Dorottya(Mrsi
(Budapes-t IV., Ujpest, To u. 1-5~; SZANTO, Tamas (Budapest IV.,
Ujpest, To u. 1-5)
Condensation of p-nitrobenzaldebyde with hydantoine. Acts. chimica Hung
29 no.3:373-381 161.
1. Chinoin Works, Ltd.
(Condensation producto(Chemistry))
(Nitrobenzaldehyde) . (Hydantoin)

ERDEY-GRUZ, Tibor.. akademikan; 13RUCKM, Gyozo, akademikus; LENGUL., Bela;
TBIZGDY-KOVATS,, Laszlo,, a tudomanyok doktora; HARDY, Gyula..
kandidatus; GERECS, Arpad, akademikus; FOLDI Zoltany- VOIACBER,
Zoltan; TUDCS, Ferenc, kandidatus; ;~UR,-Te~no; USZ, Iwo,
kandidatus; ERD.EY, Laszlo, akademikus; SCHAY, Geza, akademikuB
An account of the 1961 work of the Section of Chemical Sciencesj,
Hungarian Academy of Sciences. Kem, tud kozl 18 no-3-.343--394
162.
1. Magyar Tudomawyos Akademia Kemiai Tudomanyok Oaztalyanak titkaral
es "A MWar Tudomarps Akademia. Kemiai Tudomanyok Oazta:Lyanak
KozlemenyeiO azerkeaztoje (for Erday-Z=z). 2. Akademiai levelezo
tag (for Lengyal and Foldi). 3. "A Magyar Tudomaxyos Akademia
Kemiai Tudomanyok.Osztalyan#k Kozlemenyeiw szerkeszto bizottsagi
tagja (for Bruckner, Erdey,, Foldi,, Gerecs, Hardy, Ungye2, Schay,
Tudos).

ZoltanL Dr, 1LUUM, Dorottya, PALLOSI, Endre, SUNITEI, Eva, Dr;
OMnoin Wor?s, Ltd, -Pudapest [original language version not given].
"The 3rc,-,.i--1at-,ion of Benzo-Dihydrothiadiazine-Dioxides and Related Compounds;
...1ovel Reaction. Preliminary Communication."
Budapest, Acta Chinica Academiae Scientiarum Hungaricae, Vol 38, No 2, 1963,
!4?-149.
Abstract: C-English article] The bromination of various benzo-dihydrothiadiazine
dioxides is reported. Carried out in a water-tetrachloro methane mixture at
rooia temperature, the insoluble products have been filtered off. Some he-
tero-aromatic compounds resisted bromination, others reacted nearly quanti-
tativelyurith one molecule of bromine. The bromination in homogeneous me-
dium using dry diethyl formamide as solvent and 1,3-dibromo-4,4-dimethyl
hydantoin (DUH) as brominating agent, vas successful with c=pounds which
resisted brominaltion with elementary bromine. It is noteurorthy that the
H2N-02S group was the one removed by the DDH. The fate of the sulfamyl
cation is subject to a speculation in the article. 1 Western reference.
1/1

FOLIADOV,_j. B.
Cand Chem Sci - (diss) "Chlorination of dipentene and synthesis,
on the basis of its monochloride, of derivatives of the homo-
terpene series." Leningrad, 1961. 15 PP; (Leningrad Order of
Lenin State Univ imeni A. A. Zhdanov); 180 copies; free; (KL,
5-61 sup, 177)

FOLDIAK4..q4or.--dr.j, okleveles vogyoszmarnok, a kemiai tudomanyok kan-
didatusa., kulso munkatars; BOGNAR,, Istvan, okleveles gepeszmornok,,
tudomanyos. rminkatars
The method of the In emational Electrotachnical Commission for
the aging of transformer oils. Elektrotechnika 56 no.lo:/,44-448
0 16j.
1. Villamosipari, Kutato Intezetp Budapest, IIII., TAhel ut 23.

FOIDIAK, GABOR
Kenoolajok tapadokepossege; irodalmi osszefoglalas.
Veszprem, Hungaryj 1952,, 14 p.
Monthly List of East European AcceBsions (EEAI) LC, Vol. 8,, No. 6,, June 1959
Uncl.

MEN

lit
17. Ctill-tilollifil it 1'. "4111.1 wilat.QVIII I
it

'I'lle Nit'lik 411 i,~thlt fir (fillillillogi., 1,1v

tilt- !1m,111:11 14 111" WOO,
me ill 111,11t.c.-is v,11111-ol, 11) tilt- Islllow;w,

fir
1111,11111t. fir 1111rowtv prmhwt~ pvrfTI)l:l,111
Ily %~viglft 1411it) IJ ~fiivvljj
f in III(- raftillatt. stillil:oll lv(.4:111
niho ;)[ solveut to ill Illi, c
I-m-L x -- antollill. (if so!%cill, in tilt, ILIMf!.,0v
I ion, livicutingt% by ~vv;ghl . r mmillut of 1.11(fill-
fas Ily Nvj~iglli
jite lit Ow ralljoide solulinit. pillrelitm,,
11) tilt! 1
fill uoL IwI.-

Z4
ail g
MOW

Ci'llhgv 'wV1,1111 I/ l111101JI'l of (-Oi-livl 11) Ilw
vxflm~t 'olullon' wv "I'!
:11,111(ml a., solvA at Imm"I I') III(, IVvd.
hge I.y %k6gill rv:aflit rmw of (o
feill-v it !m JILo'ss:lv%' to lalqw tit Ho
u)
't."Irad Io solvt ril "r Itio 'tamlik." 1:~Jfcji I'lji'1'1rM-
Ifir plopel 1:11,tholL 1 ;Iv 1111
1, 1 1.1 C:~
d
-
'
VM v blislit-d It), hibm-A-w), olkliliMion v5p.,( ::Ill. if
s IVIT
poillt'k tit R.11 solvi-lit mid th% (o'il' 1 11~-' ol. h')a v
it 4
oili hy a sill, k'j-j~ V~[~;

o,
JICL;t
TN!; Oil II 11AUL lliaj,t

FOIX)IAX., GILBOR
FURFURDIDS FINMTAS KESERLEU U-7MEN: ZPROJELEMM
Ve3zprem, Hungary, 1953, 88 p.
Monthly list of East European Accessions (EEAI) LC., Vol. 8, No. 6, June 1959
Uncl.

c,,ic~ -andar is ir, tlic. lliru-ral Cil 17,
Oct./6NO.r. 19,53, Dul P~,-st,
1 . ll:c~. 10/11y
S, C Vonthly List of East Illro-ocan Accnorsions LC, 71cl. 4, "o. 3,
L arch 1055, Unc.
UM.
I NMR-t

FOLDIAKI GABOR
A nagylengyeli koolaj termikus hobontasa,- oeszefoglalo jelentes.
Budapest,, Hunggry,, 1955, 3.36 p.
Monthly List of Fast European Accessions (EEAI) LC,, Vol. 8., No. 6., June 1959
Uncl.
Ng '10

of output in connection with extr-Sctiori procerser."
MaCyar Yemikusolr- L~pja, Budapect, Vol 9, No 4, Apr. 19154, p. 11-;
SO: Fastern European Accessioiis List, Vol 3, No 10, Oct 1951,,, Lib. of Congress

HUNGARY Chomical Technology. Chemical Products and H
Their Application. Processing of Natural
Gases and Petroleum. Motor and Rocket Fuels.
Lubricants.
Abs Jour: Rof Zhur-Khimiya, No 9, 1959, '032844.
Author Foldiak, G.
Inst ot gi-vm
Title Lubricating Materials for Atomic Reactors.
Orig Pub: Technika (Magyar.), 1956, 2, No 4, 4.
Abstract: A briof exposition of the problams originating
during tho lubrication of atomic roactor compon-
onts, ospacially those units which are particu-
larly subjact to radiation, Data aro submitted
on the rosistanco to radiation by fainoral lub-
ricants of diffcront origin and coiaposition (para-
Card 1/2

HUNGARY / Chofaical Technology. Chomical Products and H
Thuir Application. rrocassing of Natural
Gases and PotroloUmi Motor and Rocket Fuels.
Lubricantak
Abs Jour: Rof Zhur-Oi6lya, No 9, 1959t 32844.
Abstract: ffin, aromatic, otc.); about the behavior under
roactor conditions of cartain synt'hotic lubri-
cants (octadocylbonzono, polypropylono oxides,
siliconus) and consistent lubricants. Ro-
zonfolld.
Card 2/2