MEDICO-BIOLOGICAL STUDIES ON HYDROCARBON YEASTS

• Document Type: CREST
• Collection: General CIA Records
• Document Number (FOIA) /ESDN (CREST): CIA-RDP79-00798A000400090013-1
• Release Decision: RIFPUB
• Original Classification: K
• Document Page Count: 14
• Document Creation Date: December 27, 2016
• Document Release Date: January 14, 2013
• Sequence Number: 13
• Content Type: SUMMARY

Declassified and Approved For Release 2013/01/14: CIA-RDP79-00798A000400090013-1
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MEDICO-BIOLOGICAL STUDIES ON HYDROCARBON YEASTS
Exerpts from the Russian-language book Mediko-Biologlgheskiye
Issledovaniva Uglevodorodnykh Drozhzhey (English version above),
Nauka Press, Moscow, 1972
CONTENTS
Page
Table of Contents . 1
Introduction 14
Results of Medico-Biological Tests on Hydrocarbon Yeasts
(A, A. Pokrovskiy) 20
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Table of Contents
Introduction
5
Statement of Problem
Pokrovskiy, A. A. Prospects for Using Proteins of
Unicellular Organisms. 9
Pokrovskiy, A. A. Medico-Biological Aspects of
Hydrocarbon Yeast Tests, 59
Yeroshin, V. K. and Dedyukhina, E. G. Hydrocarbons Syn-
thesized by Microorganisms. 71
Studies on the Biological Value and Harmlessness
of BVK* and Biolo ical Oil-Seed Meal
?riments on Small Laboratory Animals and Dogs
Neyman, I. M. Some Considerations Regarding the Pos-
sibility of the Cancerogenic Activity of BVK. 75
Neyman, I. V., Arkhipov, G. N., Kafeyeva, T. A? Mirzoyan,
Ye. Ye. (deceased), Azhnina, G. V. On the Problem of
BVK Cancerogenicity. 82
Shabad, L. M., Khesina, A. Ya., Serkovskaya, G. S.,
Ogloblina I. A.,and Fridman, Ya. S. Determination
of 3.4-benzpyrene in BVK and Raw Materials Used in
the Process of Its Obtaining. 89
Khesina, A. Ya. and Fedoseyeva, G. Ye. Spectral-Fluores-
cence Methods for Determining a Number of Aromatic
Polycyclic Hydrocarbons. 94
*BVK -- protein-vitamin concentrates
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Pokrovskiy, A. A. and Somin, V. I. Amino Acid Composition
of Some Unicellular Organisms. 103
Pokrovskiy, A. A. and Timoshenko, V. A. Some Data on the
Total Content of Nucleic Acids in the Biomass of
Unicellular Organisms. 109
Solov'yev, L. M. and Ivashchenko, N. V. Biological Value
of Proteins of BVK and Biological Oil-Seed Meal. 112
Solov'yev, L. M. and Somina, S. I. Content of Sulfhydryl
Groups in the Tissues of Rats when They Are Given
BVK Rations. 115
Solov'yev, L. M., Levachev, M. M., and Ptitsyna, T. M.
Comparative Evaluation of the Indexes of Fat
Metabolism in Rats Which Received BVK and Biological
Oil-Seed Meal as a Source of Protein. 120
Levachev, M. M. The Composition of Higher Fatty Acids
of the Tissues of Rats Receiving Rations with
Different Amounts of BVK as a Protein Source. 126
Solov'yev, L. M. and Levachev, M. M. The Dynamics of
Changes in the Composition of Higher Fatty Acids
of Blood Serum, Liver, and Fatty Tissue of Rats
after Changing Them from a Diet Containing BVK to
a Standard Pelletized Feed, 136
Solov'yev, L. M., Levachev, M. M., and Ptitsyn, T. N.
Studies on Some Indexes of Lipid Metabolism in
Chickens Receiving Various Amounts of BVK in Their
Food as a Source of Protein.
2
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Solov'yev, L. M. and Levachev, M. M. The Effect of BVK
and Hydrolytic Yeasts on the Content of Cholesterol
in the Blood Serum, Liver, and Aorta of Rats of
Various Ages.
Markelova, V. F? Tatsiyevskiy, V. A., and Levachev, M. M.
Some Peculiarities of the Lipid Metabolism in the
Livers of Rats Which Received Rations with 100 Per-
cent Replacement of Protein with the Proteins of
Biological Oil-Seed Meal.
Solov'yev, L. M., Levachev, M. M., and Ptitsyna, T. N.
A Study on the Composition of the Phospholipids of the
Liver and Blood Serum of Rats Which Received BVK or
Hydrolytic Yeast as a Source of Protein.
Solov'yev, L. M. and Somina, S. I. Sugar Content in the
Blood of Rats Fed with Addition of Protein-Vitamin
Concentrates.
Pokrovskiy, A. A., Shcherbakova, A. I., Litvinova, G. S?
and Putyata, Ye. V. Effects of BVK on the Enzymic
Spectra of the Livers of Rats,
Pokrovskiy, A. A., Shcherbakova, A. I., Litvinova, G. S.
and Putyata, Ye. V. Effects of BVK on the Enzymic
Spectra of the Blood of Rats.
Pokrovskiy, A. A., Shcherbakova, A. I? Litvinova, G. S.,
and Putyata, Ye. V. Effects of Biological Oil-Seed
Meal on the Enzymic Constellations of the Liver and
Blood of Rats.
146
150
154
158
161
167
172
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Pokrovskiy, A. A. and Korovnikov, K. A. The Protein and
Isoenzymic Spectra of the Blood Sera of Rats when
the Protein of the Rations is Replaced with the
BVK Protein. 176
Pokrovskiy, A. A. and Korovnikov, K. A. Effects of
Biological Oil-Seed Meal and Hydrolytic Yeasts
on the Protein and Isoenzymic Serum Spectra of Rats. 181
Markelova, V. F. and Levachev, M. M. Dynamics of the Dis-
tribution of C14-Octadecane in the Organs of Rats Fed
with Rations in Which 25 Percent of the Protein was
Replaced with BVK Proteins. 187
Markelova, V. F. The Inclusion Rate of 2-C14-Acetate of
Sodium in the Molecules of Cholesterol and Fatty
Acids of the Organs of Rats Receiving Rations in
Which 25 Percent of the Proteins were Replaced with
a BVK Oil-Seed Meal.
Pokrovskiy, A. A., Andriasov, A. N., Basargin, N.
N.,
192
Levachev, M. M., Pozdnyakov, A. L., Levitina, N. A.,
and Zolotova, A. I. Hydrocarbon Content in the Organs
and Tissues of Rats Fed with the Addition of BVK. 194
Pokrovskiy, A. A., Andriasov, A. N., Basargin, N. N.,
Levachev, M. M., Pozdnyakov, A. L., Levitina, N. A.,
and Somina, S. I. Hydrocarbon Content in the Organs
and Tissues of Animals at Various Times after the
Exclusion of BVK from Their Rations.
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krovskiy, A. A., Ushakova, T. M., Eller, K. I? Ponomareva,
L. G., and Kuznetsov, D. I. Determination of the
Content of Residual Hydrocarbons in Protein-Vitamin
Concentrates (BVK). 206
11...rovskiy, A. A. Nikolayeva, M. Ya? Ponomareva, L. G.,
and Gapparov, M. MO GO Studies on Nutrient Yeasts
for the Content of Aflatoxins*. 210
Pt
krovskiy, A.
Eller, K.
Aft
Ponomareva, L. G., Ushakova, T. M.,
and Kuznetsov, D. I. Determination
of Hydrocarbons (n-alkanes) in the Tissues of
Animals. 214
?fremov, V. V., Maslenikova, Ye. M., Penar, 0. I.,
Gvozdova, L. G., Krayko, Ye. A., Vaynerman, A. Sh.,
Smirnova, A. N., and Soloveyeva, L. Ya. Effects of
Protein-Vitamin Concentrates on Individual Indexes
of Vitamin Metabolism in Rats. 218
YA'fremov, V. V., Maslenikova, Ye. M., Penar, 0.
Gvozdova, L. G? Krayko, Ye. A., Vaynerman, A. Sb.,
Smirnova, A. N., and Soloveyeva, L. Ya. On the Study
of Individual Indexes of Vitamin Metabolism in White
Rats Receiving Biological Oil-Sc,ed Meal in their
Rations. 223
rieJ tier, T. N. and Mikhlin, S. Ya. (deceased). Effects
of Various Yeasts (BVK, biological oil-seed meal and
-4-A found in available sources ? word transliterated from Russian.
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dry brewing yeasts) on the Secretory Activity of
Gastric Glands in Dogs. 227
Zitler, T. N. and Mikhlin, S. Ya. (deceased). Effects
of Various Amounts of BVK in the Rations on the
Secretory Activity of Gastric Glands in Dogs. 236
Zitler, T. N. and Mikhlin, S. Ya. (deceased). Effects
of Biological Oil-Seed Meal on the Secretory Activity
of Gastric Glands in Dogs. 241
Laktayeva, T. V. Effects of BVK on the Exacrinous
Activity of the Pancreas. 248
Laktayeva, T. V. Effects of Biological Oil-Seed Meal
on the Enzyme-Secreting Function of the Pancreas. 252
Andriasov, A. N. and Levitina, N. A. Effects of Various
Amounts of BVK in the Rations on the Conditioned-
Reflex Activity of Rats (Report 1). 256
Andriasov, A. N. and Levitina, N. A. Effects of Various
Amounts of BVK in the Rations on the Conditioned-
Reflex Activity of Rats (Report 2) 261
Volgarev, M. N. and Kudryavtseva, L. A. Effects of Rations
with Various Contents of BVK and Biological Oil-Seed
Meal on the Hematogenic System (..)f Rats. 268
Meshkov, N, V., Skirko, B. K., and Asfagan, F. M. Mor-
phological and Histochemical Changes in the Organs of
Laboratory Animals Receiving BVK in Their Rations. 275
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Meshkov, N. V. and hsfagan, F. M. On Pathomorphologic
Changes in Experimental Animals Receiving BVK for
a Long Period of Time.
Gadzhiyeva, Z. M. Morphological Changes in the Viscera
of Rats Fed with Biological Oil-Seed Meal.
Gadzhiyeva, Z. M. Microliths in the Kidneys of Rats
Fed with Biological Oil-Seed Meal.
Experiments on Monkeys
Andriasov, A. N., Gvazava, I. S., Andreyeva, A. V., and
Dzheliyev, I. T. Clinical Indexes in Monkeys Fed
with Rations Containing BVK.
Annenkov, G. A., Andriasov, A. N., Pachaliya, N. A.,
Ivashchenko, N. V., and Solov'yeva, L. M. Blood
Serum Proteins of Monkeys Fed with the Addition
of BVK.
Solov'yeva, L. M., Levachev, M. M., and Andriasov, A. N.
The Condition of Lipid Metabolism in Monkeys Fed
with the Addition of BVK.
Pokrovskiy, A. A., Karpacheva, V. A., Shcherbakova, A. I.,
Litvinova, G. S., Petrash, L. Ye., and Putyata, Ye. V.
Enzymic Constellations in the Liver of Monkeys Fed
with BVK-Containing Rations.
Pokrovskiy, A. A., Shcherbakova, A. I., Putyata, Ye. B.,
284
289
296
301
309
313
316
Litvinova, G. S. , and Petrash, L. Ye. Enzymic
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Constellations in the Blood of Monkeys Fed with
BVK-Containing Rations. 319
Markelova, V. F., Levachev, M. M., and Dikovenko, Ye. A.
Comparative Characteristics of the Absorption and
Distribution of Octadecane in the Organs of Rats
and Monkeys.
Dzheliyeva, Z. N. and Andriasov, A. N. Effects of BVK
on the Content of Vitamin B12, Folic Acid, and
Folinic Acid in the Blood of Lower Monkeys.
Kuksova, M. I. and Andriasov, A. N. Effects of BVK and
Hydrolytic Yeasts on the Hematogenic System of Lower
Monkeys. 330
Meshkov, N. V., Pozdnyakov, A. L., and Andriasov, A. N.
The State of the Viscera of Monkeys Kept on a Diet
with the Addition of BVK for a Long Period of Time. 336
322
326
Ii1212gio1 Value and Harmlessness of Animal Husbandry Products
Obtained as a Result of Feeding Agricultural Animals with BVK
and Biological Oil-Seed Meal. Experiments on Small Labs=
Animals and Dogs
Solov'yeva, L. M., Levachev, M. M., and Ptitsyna, T. N.
Effects of Rations Containing the Flesh of Pigs and
Chickens Fed with the Addition of BVK on the Lipid
'Metabolism Indexes of Rats.
Solov'yeva, L. M., Ivashchenko, N. V., Nosova, O. Ael
Korf, I. I., and Cheremnykh, Ye. G. Effects of Dairy
Products Obtained from Cows Fed with the addition of
8
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BVK on the Changes in the Weight of Rats and
Some Aspects of Metabolism.
Solov'yeva, L. M., Levachev, M. M., and Ptitsyna, T. N.
Peculiarities of Fat Metabolism in Rats Receiving
Dairy Products from Cows Fed with the Addition of
BVK.
Pokrovskiy, A. A. Shcherbakova, A. I., Litvinova, G. S?
and Putyata, Ye. V. Effects of Dairy Products from
Cattle Fed with the Addition of BVK on the Enzymic
Spectra of the Liver and Blood of Rats.
Solov'yeva, L. M., Ivashchenko, N. V., and Mikhaylovskaya,
V. PO
Some Indexes of the Biological Value of Eggs
Obtained from Hens Fed with the Addition of Various
Amounts of BVK.
Solov'yeva, L. M., Levachev, M. M., and Ptitsyna2T. N.
Peculiarities of Lipid Metabolism in Rats Receiving
Rations with Eggs from Hens Fed with the Addition
of BVK.
Solov'yeva, L. M., Levachev, M. M? and Ptitsyna, T. N.
The State of Lipid Metabolism in Rats Kept on Rations
Consisting of Sets of Products obtained from Agri-
cultural Animals Fed with the Addition of BVK.
Pokrovskiy, A. A. and Levachev, M. M. The Content of
Higher Fatty Acids in Products Obtained from Agri-
cultural Animals Fed with the Addition of BVK and
9
344
346
349
352
354
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the Composition of Fatty Acids in the Tissues of
Rats Receiving These Products. 363
Pokrovskiy, A. A., Shcherbakova, A. I., Litvinova, G. S.,
and Putyata, Ye. V. Effects of Products from Agri-
cultural Animals Fed with the Addition of BVK on
the Enzymic Spectra of the Liver and Blood of Rats. 369
Solov'yeva, L. M., and Somina, S. I. Sugar Content in
the Blood of Rats Receiving Rations of Products ,
Obtained from Agricultural Animals and Poultry Fed
with the Addition of BVK or Biological Oil-Seed
Meal. 373
Kudryavtseva, L. A. The State of the Hematogenic System in
Rats Kept on Diets of Products Obtained from Agricul-
tural Animals and Poultry Fed with the Addition of
BVK. 376
Skirko, B, K. and Meshkov, N. V. Morphology of the
Viscera of Rats Fed on Products Obtained from
Agricultural Animals and Poultry Receiving Rations
with BVK. 380
Pozdnyakov, A. L. Effects of Nutrient Products Obtained
from Agricultural Animals and Poultry Fed with the
Addition of BVK on the Structure of the Viscera of
White Rats.
10
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Experiments on Monkeys
Andriasov, A. N., Gvazava, I. S., Andreyeva, A. Z.,
and Dzheliyev, I. T. Clinical Indexes of Monkeys
Receiving Products Obtained from Agricultural Animals
and Poultry Fed with the Addition of BVK. 391
Annenkov, G. A., Andriasov, A. N., Pachaliya, N. A.,
Solov'yeva, L. M., and Ivashchenko, N. V. Effects .
of Nutrient Products Obtained as a Result of Adding
BVK to the Food Rations of Agricultural Animals on
the Blood Proteins of Lower Monkeys. 401
4olov'yeva, L. M., Levachev, M. M., and Andriasov, A.N.
The State of Lipid Metabolism in Monkeys Kept on
Rations with Dairy Products and Eggs Obtained from
Agricultural Animals and Poultry Fed with the
Addition of BVK. 404
t.,okrovskiy, A. A., Karpacheva, V. A., Shcherbakova,
A. I., Putyata, Ye. V., Litvinova, G. S., and
Petrash, L. Ye. Effects of Products Obtained from
Agricultural Animals Fed with the Addition of BVK
on the Enzymic Constellations of the Liver and Blood
in Monkeys. 407
bzheliyeva, Z. N. and Andriasov, A. N. The Content of
Vitamin B12, Folic Acid, and Folinic Acid in the
Blood and Liver of Lower Monkeys Receiving Products
from Agricultural Animals Fed with Addition of BVK. 412
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Kuksova, M. I. and Andriasov, A. N. Changes in the
Hematogenic System of Monkeys Fed on Products
Obtained from Agricultural Animals Receiving BVK
as a Part of Their Rations.
Pozdnyakov, A. L., Meshkov, N. V., and Andriasov, A. N.
Morphological Characteristics of the Organs of
Monkeys Fed with Products from Agricultural Animals
Whose Rations Included BVK.
Control Experiments of Volunteers
Pokrovskiy, A. A., Andriasov, A. N., Loranskaya, T. 1.,
and Levitina, N. A.
Control Observations on the
Health of Volunteers Using Meat Products Obtained
from Agricultural Animals Fed with the Addition of
BVK.
Loranskaya, T. I. and Andriasov, A. N. Indexes of
Protein-Fat Metabolism in Volunteers Using Meat
Products Obtained from Agricultural
with the Addition of BVK.
Pokrovskiy, A. A. and Zikeyeva,
Some Enzymes in Volunteers
Pokrovskiy, A. A., Andriasov, A
Animals Fed
416
423
427
436
V. K. The Activity of
Using New Meat Products. 440
. N., Loranskaya, T. I.,
? Zikeyeva, V. A., and Levitina, N. A. Control Obser-
vations on the Health Conditions of Volunteers Using
Subproducts from Agricultural Animals Fed with the
Addition of BVK.
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Pokrovskiy, A. A. Results of Medico?Biological Tests
on Hydrocarbon Yeasts. 449
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