THE GLOBAL AIDS DISASTER: IMPLICATIONS FOR THE 1990S <SANITIZED>

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Approved for Release: 2017/08/31 C06547069 Director of Central Intelligence PROJECT NUMBER A 6:)E FM NUMBER OF PAGES 0024 16, TOTAL NUMBER OF COPIES ctSD DISSEMINATION DATE F5' - 1 JOB NUMBER 4,a,(,,� 00 (04 4,9 \ The Global AIDS Disaster: Implications for the 1990s Interagency Intelligence Memorandum 1467 651-651 REGISTRY FILE COPY/SOURCED COPY CPAS/INC/CONTROL BRANCH ROOM 7G07 OHB NIAR'"" I , n BO i%0"; :L.E OUT e t NI IIM 91-10005 July 1991 Copy 651 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 Warning Notice Intelligence Sources or Methods Involved (WNINTEL) National Security Unauthorized Disclosure Information Subject to Criminal Sanctions Dissemination Control Abbreviations NOFORN (NF) Not releasable to foreign nationals NOCONTRACT (NC) Not releasable to contractors or contractor/consultants PROPIN (PR) Caution�proprietary information involved ORCON (OC) Dissemination and extraction of information controlled by originator REL... WN All material on this page is Unclassified. This information has been authorized for release to... WNINTEL�Intelligence sources or methods involved Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 Director of Central Intelligence NI IIM 91-10005 The Global AIDS Disaster: Implications for the 1990s Information available as of 15 July 1991 was used in the preparation of this Memorandum. The following intelligence organizations participated in the preparation of this Memorandum: The Central Intelligence Agency The Defense Intelligence Agency The National Security Agency The Bureau of Intelligence and Research, Department of State also participating: The Deputy Chief of Staff for Intelligence, Department of the Army The Director of Naval Intelligence, Department of the Navy The Assistant Chief of Staff, Intelligence, Department of the Air Force Director of Intelligence, Headquarters, Marine Corps This Memorandum was approved for publication by the Chairman of the National Intelligence Council. Se July 1991 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 The Global AIDS Disaster: Implications for the 1990s � AIDS cases worldwide will increase rapidly during the 1990s, from about 1.5 million now to a cumulative total of more than 10 million by the end of the century. � Whatever the success of research on vaccines and treatment, the upward trend in AIDS cases through the mid-1990s will not be affected. � Currently, the problem is worst in Africa, but rapidly spreading infections in India, Brazil, and Thailand will contribute significantly to an estimated 45 million infections worldwide by 2000. � By any measure�deaths, number of people infected, economic cost�the impact of AIDS will be far greater in the 1990s than in the 1980s. � The United States will face three basic foreign policy problems: How to allocate assistance for AIDS prevention, how to manage the testing and distribution of a vaccine, and how to deal with countries that are heavily afflicted with AIDS and consequently undergo substantial economic and political change. 'steer. NI IM 91-10005 July 1991 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 Figure 1 Global Human Immunodeficiency Virus (HIV): Rates of Infection per 100,000 Persons f-i2EILv 'Rem a MI g..rga4 avpct agw *1,000 to 5,000 Burundi Cameroon Congo French Guiana Guinea-Bissau Haiti Ivory Coast Nicaragua Rwanda Swaziland 1,200 1,975 2,598 4,921 _ 2,933 1,941 3,082 1,199 3,796 1.164 - Tanzania 2,977 Trinidad and Tobago 1,145 Zaire 1,586 00 to 1,000 C pe Verde 6 D rninican Republi 9 Gambi Gabon Hondura Kenya ozambigue Namibia Senegal Suriname Thailand 6 756 792 662 9 7 200 to 500 Angola 496 Argentina 276 Bahamas, The 476 Belize 351 Benin 310 Brazil 451 Burkina 214 200 to 500 Ecuador 233 France 441 Ghana 288 Grenada 430 Guinea 241 Guyana 387 Mali 288 Martinique 246 Netherlands 220 Nigeria 408 Panama 202 South Africa 369 Spain 419 Switzerland 262 United States 396 Uruguay 320 Less than 200 All other countries Boundary representanon Is not necessanly authoritative. �er iv 722488 (301111) 7-91 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 Key Judgments The number of AIDS cases worldwide will increase rapidly during the 1990s, from about 1.5 million as of early 1991 to a cumulative total of more than 10 million by the end of the century. The great majority of the new AIDS cases during the 1990s will occur in Sub-Saharan Africa, with North America a distant second. This increase is inevitable because about 11.5 million people are now infected with the virus that leads to AIDS, a figure we expect to quadruple by 2000. Current preventive measures are not being used on a sufficient scale to reverse the spread of the disease. No "cure" for HIV infection is in prospect. Even if an effective vaccine is devised within the next few years, technical and financial obstacles probably will limit its use and, thus, its impact on the spread of the disease. Whatever the success of any of these measures, the upward trend in AIDS cases through the mid-1990s will not be affected. The AIDS epidemic is at its worst in Sub-Saharan Africa. Some 7 million Africans are already infected. By the mid-1990s the cumulative total probably will exceed 20 million, and beyond 2000 infection rates will be up to 40 percent for typical young-adult populations in urban areas, with life expectancy at birth reduced by 15 years or more. This explosion of AIDS cases will substantially weaken the political elites and damage the economies of affected African countries. A greater portion of their limited budgets will have to be devoted to prevention and treatment. At the same time, the dangers posed by AIDS and the AIDS-in- duced economic decline will discourage foreign investment. During the 1990s, AIDS in the Caribbean countries will proceed on a scale comparable to that in Africa, with similar dire results for the affected societies. In India, AIDS is a major threat on the horizon, but the government probably will not take adequate steps to counter the disease during the next five years. This neglect has the potential of allowing replication of the African experience in 10 or 15 years. Brazil is in a similar situation, whereas Thailand's early prevention programs may slow the epidemic. Using any standard of measure�deaths, number of people infected, economic cost�the impact of AIDS will be much greater in the 1990s than it was in the 1980s. The resulting social and economic calamity will v -StefeL Approved for Release: 2017/08/31 C06547069 Isr.et Approved for Release: 2017/08/31 C06547069 Data Deficiences No country has an accurate count of the number of people infected by HIV. Much of the testing to date comprises small samples of high- risk groups, such as prostitutes and drug addicts, and is therefore unrepresentative of entire populations. Within countries, infection rates vary widely from region to region, further complicating the problem of generalizing from a small sample. Counting the number of AIDS cases and AIDS-related deaths is also difficult, particularly since health care systems in many countries lack the required diagnostic ability. Moreover, some governments suppress what infor- mation they have The data in figure 1 are Intelligence Community estimates of HIV prevalence from open-source information in conjunction with intelli- gence reports. Our aggregate figures are somewhat higher than those published by the World Health Organization. In some countries�India, Brazil, and Nigeria for example�the data are particularly weak. Our world total may well be off by more than a million. We believe that further improvements in data collection will probably reveal a crisis of even greater magnitude than is portrayed in this Memorandum. For instance, recent refinements of information mostly account for larger figures for several countries than in our previous Estimates. force the United States to make politically sensitive decisions regarding the prevention programs that it will encourage and the aid it will dispense. The three basic foreign policy problems are: � How to allocate assistance for AIDS prevention. Anti-AIDS programs are most effective when started early in an epidemic, but most of the money now goes to countries where the disease is already well entrenched. � Managing the testing and distribution of a vaccine. Political friction will arise as countries haggle over the terms for allowing tests to take place among their people and over access to vaccines. � Dealing with countries that are heavily afflicted with AIDS. Achieving US objectives for development in less developed countries will be made much more difficult in AIDS-stricken countries. Compared with the situation in the less developed countries, the West is better equipped to combat AIDS. Nevertheless, AIDS will spread slowly there, but without reaching the epidemic proportions of Africa or the Caribbean. This information is vi Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 Contents Page Key Judgments Discussion A Time Bomb for the 1990s AIDS Is Now Global V 1 1 1 AIDS in the Industrial Countries AIDS in the Developing Countries Africa: Getting Worse The African Response: Too Little, Too Late Grim Future: A Changed Continent Will Africa's Experience Be Repeated Elsewhere? Other AIDS Hotspots Around the Globe Thailand 3 5 7 7 7 8 8 8 Brazil 8 India 11 The Caribbean Other Problem Countries Prevention Strategies Implications of Research on Treatments and Vaccines Treatment for HIV Infection Vaccines 11 11 12 13 13 14 Other Technical Progress International Transmission Implications for the United States What To Spend Where Vaccine Politics 14 14 15 15 15 Dealing With Decimated Countries 16 Military Basing and Access Issues 16 vii Approved for Release: 2017/08/31 C06547069 tiscet Approved for Release: 2017/08/31 C06547069 Basic Facts About AIDS Acquired Immune Deficiency Syndrome (AIDS), first identified in 1981, is the final stage of a viral infection caused by the Human Immunodeficiency Virus (HIV). Medical experts recognize two strains: HIV-1, discovered in 1983, which is gener- ally accepted as the cause of most AIDS cases throughout the world; and HIV-2, discovered in West Africa in 1986 and later found in some former Portuguese colonies elsewhere and in Eu- rope. HIV is a retrovirus: a virus that inserts� probably for life�its genetic material into the cells of the host at the time of the infection. Inasmuch as the ability to remove genetic material from cells is far beyond the capability of current medical science, the infection may be said to be incurable. The Course of HIV Infection Following infection with HIV, only the most so- phisticated tests can detect its presence during the first weeks or months. After this period, the infected person's system begins producing antibod- ies to HIV, which blood testing can reveal. Such tests were first available in 1985 and vary as to their ability to detect HIV. About half of the infected people will develop AIDS symptoms in less than 10 years, and some within five years. The incubation period can be lengthened with drug therapy, and it is shorter where health care is poor. Death from AIDS usually occurs in one to two years; infants generally die more rapidly. Everyone infected will acquire AIDS, and AIDS is always fatal. Transmission Three main routes of transmission exist: � Contact with infected blood or blood products via transfusions, transplants, or shared needles. � Sexual contact with an infected person. � Infection of infants born to an infected mother. �irt. Preventive Measures A contaminated blood supply is often the first sign of an incipient AIDS epidemic, and it is relatively easy to control. Donated blood should be tested for HIV, which is costly but feasible. The next stage of an epidemic is often the preva- lence of HIV infection among prostitutes, prison- ers, or intravenous (1-I drug users. This is far more difficult to control, and few countries have taken meaningful steps to do so. When the virus infects IV drug users, it spreads rapidly if needles are shared. Distributing needles free, as in the Netherlands, is one way of combat- ing this, with differing claims as to success. The spread of HIV in the general population is typically very slow, yet potentially it is the source of far greater numbers of AIDS cases than in the smaller groups of IV drug users and male homo- sexuals. Once the infection is established in the general population, it spreads mainly by sexual contact and thus may be impossible to eradicate. Reducing the prevalence of other sexually trans- mitted diseases can slow the transmission but would require public health expenditures in LDCs far greater than any to date. In addition to all of these steps, behavioral changes�less promiscuity and more frequent con- dom use�by large numbers of people are essential for effective control. The main programs to achieve this are dissemination of information and distribu- tion of condoms. Many public health experts are pessimistic about the prospect that the necessary behavioral changes will occur. Some decry the lack of research into prevention measures that women could use. Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 Discussion' The number of Acquired Immune Deficiency Syn- drome (AIDS) cases worldwide will increase rapidly during the 1990s, from about 1.5 million people as of early 1991 to a cumulative total of more than 10 mil- lion by the end of the century. Most of those infected will die within a year or two of developing AIDS symptoms, whether or not they have access to modern health care. This increase in AIDS cases is inevitable because about 11.5 million are now infected, all of whom are vulnerable to AIDS-related diseases Past 1995, the number of AIDS cases will continue to grow. Current prevention programs will begin to pay off at the margin, but by then AIDS will be deeply entrenched in many countries. After 2000, the trend in AIDS deaths will depend crucially on changes in behavior or whether a scientific breakthrough is made during the next several years. For the 1990s, however, the trend is fairly clear and virtually independent of new scientific progress�barring development of a drug that disables the virus However the impact of the disease is reckoned�by deaths, AIDS cases, or monetary losses�it is just beginning. The worldwide impact during the 1990s will be five to 10 times that of the 1980s. As this process unfolds, the United States will find itself progressively more involved with prevention programs and with the political changes that AIDS will bring about in the hard-hit countries A Time Bomb for the 1990s Much of the difficulty in halting the spread of AIDS stems from the long incubation period of the disease. Unlike any deadly epidemic of the past, AIDS takes ' This Memorandum was requested by the Assistant Secretary of State for Oceans and International Environmental and Scientific Affairs. It focuses on the worldwide scope and impact of the disease during the 1990s. For a more complete assessment of Africa's prospects, see SNIE 70-90, Sub-Saharan Africa's Worsening AIDS Crisis, August 1990 1 years to develop after the initial infection. During this time, infected people can infect others This lengthy incubation makes it hard to detect early signs of an AIDS epidemic. In the absence of an outbreak of AIDS cases, countries rarely undertake the rigorous test sampling needed to accurately mea- sure Human Immunodeficiency Virus (HIV) preva- lence. More commonly, recognition of the disease is delayed until the epidemic is well established making preventive action far more difficult Indeed, AIDS is unstoppable in the short term. Because it takes an HIV infection so long to develop into AIDS, virtually all of the AIDS cases that occur during the next five years will be the result of existing infections. Therefore, the epidemic cannot be materi- ally reduced in this time frame by any reduction in new HIV cases. Worldwide, millions of HIV infec- tions are set to explode into AIDS during the 1990s. The long incubation period probably contributed to initial overestimates of how fast AIDS would spread globally. In the early 1980s, many cases of AIDS went undetected. As AIDS became better understood, the number of individuals diagnosed increased much more rapidly than the rise in the actual number of cases. Some projections of these rising numbers of cases diagnosed resulted in astronomical forecasts for the late 1990s. By now, the number of diagnoses probably has about caught up with the number of actual cases in the industrial countries but not yet in the Third World. AIDS Is Now Global The great majority of the new AIDS cases during the 1990s will occur in Sub-Saharan Africa, with North America a distant second. This is simply a projection Thteret.... Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 AIDS: The New Plague? Bubonic plague�the "black death"�is the best known of the earlier pandemics. It first appeared in the sixth century, then in the 14th, when it killed 20 million people in Europe, a quarter to a third of the population. Its last major appearance in England was the Great Plague of 1665, described in Defoe's Journal of the Plague Year. France underwent its last epidemic in 1720. Later outbreaks occurred in Asia, Africa, and, as recently as 1983, in the United States. WHO AIDS logo AIDS differs from the plague in several important ways: AIDS Incubation period lasts up to 10 years or more. Infection likely to persist in large parts of the world's population. Spread primarily by sexual contact or needle sharing. Prevention efforts aim at public aware- ness and behavior change. Other measures are of secondary importance so far. Natural immunity uncertain, not yet observed. No vaccine, no cure. The impact of AIDS may not approach the historical significance of the black death. By killing some of the rich and many of the poor, the plague helped end the feudal system. Serfs inherited or occupied estates whose owners had died. Peasant revolts and severe labor shortages made workers more mobile; many moved to towns, forming the nucleus of the urban middle class. Some historians argue that the black death ended wars everywhere in Europe and, by weakening Viking settlements in Greenland and Vinland during one of its early surges, set back Europe's reach toward the New World. Bubonic Plague Illness comes on quickly, spreads rapidly, disap- pears only to reoccur episodically. Spread by rodent fleas. Personal measures for protection were not known, but public health mea- sures are now effective. Rodent and human populations build natural im- munity on exposure. Vaccine now available, can be cured if treated quickly. 2 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 Figure 2 AIDS Cases and HIV Infections Estimated Through 2000 Millions of people 0 Through 1991 Through 2000 331529 7-91 of the location of current HIV infections: about two- thirds in Africa and one-tenth in North America Elsewhere, the AIDS epidemic generally is in an earlier stage, though practically every country has reported the presence of AIDS, and some have several thousand cases. The Caribbean has some of the highest infection rates in the world. In some coun- tries�India, Brazil, and Thailand, for example�the infection rate is comparatively low overall but quite high among certain segments of the population and growing rapidly with little to impede it We believe that during the 1990s some 35 million people or more will become infected, these in addition to the 11.5 million estimated to date. About 85 per- cent of the new infections will occur in developing countries, mainly in Africa. The epidemic will spread fastest in Asia and South America, setting the stage for a large increase in AIDS cases after 2000. 3 AIDS in the Industrial Countries Industrial countries have important advantages over developing countries in combating AIDS: � Greater literacy. This makes publicity campaigns more effective, facilitating the spread of knowledge necessary to avoid infection. � Money. AIDS prevention campaigns are expensive, as they require widespread testing of blood, educa- tional programs, and other costly measures. Well- developed health care systems aid in tracking the epidemic and assessing the effectiveness of policies. � Lower prevalence of sexually transmitted diseases (STDs). A person already infected with an STD, such as gonorrhea or syphilis, may be as much as 10 times more likely to contract HIV from a sexual contact with an infected person than is a person without an STD. The situation in the industrial countries, however, is favorable only in comparison with Africa and some other places in the developing world. Western Europe as a whole reports some 50,000 cumulative AIDS cases; Switzerland, for example, with a population of 6.9 million, has had more than 1,000 AIDS deaths. The epidemic in Western Europe afflicts mainly homosexuals as well as a growing number of intrave- nous (IV) drug users. IV drug users in Eastern Europe�notably in Poland and Yugoslavia�have also been infected, although overall rates are much lower than in the West. The main source of AIDS in Eastern Europe and the Soviet Union has been the government health care infrastructure, which has unwittingly infected patients through the practice of using needles more than once. The mid-1990s will see great increases in AIDS cases in some industrial countries, given the extent of today's HIV infections. Beyond that, and into the next century, the outlook is mixed. While some affected groups have made substantial behavioral changes (US homosexuals, for example), other groups (IV drug 'Ll'er Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 3itrefe& Figure 3 Estimated HIV Infections and AIDS Cases, 1991 a Percent Asia and Oceania 7 Europe 6 South America 11 North America 11 Sub-Saharan Africa 65 I_ a AIDS in the Middle East and North Africa appears to be negligible as compared to other regions. Asia and Oceania 1 Europe 6 South America 7 North America 21 Sub-Saharan Africa 65 AIDS Cases Total: 1.5 million users and, in some countries, heterosexuals) are at risk of accelerating infection rates. HIV infection among these groups is characterized by rapid spread, then saturation. Among heterosexuals in industrial coun- tries, there is likely to be a very slow buildup, but ultimately many more AIDS cases than in the smaller cohorts of homosexuals and IV drug users. AIDS will affect people in every demographic group, but it will remain predominantly a disease of the poor, who are prone to riskier behavior regarding drugs and sex. btbc, 331530 7-91 AIDS will be a growing concern in industrial coun- tries. The major issues will focus on health care cost� which will grow rapidly in the 1990s�and equity in benefits and burdens. Should an effective vaccine or treatment be discovered, questions will arise over how rapidly and cheaply it will be made available and over the patent rights and liability of drug manufacturers. 4 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 sckt The Epidemic Has Limits Epidemics typically reach a point of "satura- tion" whereby incidence levels off at well under 100 percent of the population. This happens because some people either are naturally im- mune or avoid exposure to the disease. Thus, AIDS will not wipe out entire populations, but the point of saturation for HIV probably varies substantially from population to population and cannot be predicted with any precision. AIDS in the Developing Countries Without the industrial countries' advantages, the LDCs will be far more vulnerable to AIDS. The disease will bring fundamental changes in the eco- nomic structure of the developing countries where it is widespread Impact on the Work Force. The years of highest economic productivity coincide with the age groups of highest infection rates. Workers will begin succumb- ing to the disease in greatest numbers just as they finish their education or apprenticeships and enter their most productive years. Regional Trade. Governments may come under pres- sure to "protect" their citizens by restricting the free flow of labor from countries that have higher rates of infection than they. Foreign investment will also be hurt. In Africa, Western investors probably will see AIDS as just one more reason to put their money elsewhere. Expatriate workers from industrial coun- tries may prove increasin 1 reluctant to come to AIDS-stricken countries Health Care Expenditures. It is not clear just how much governments or international organizations will choose to spend on care for AIDS sufferers. The harsh reality is that most victims will receive little treatment beyond home care. Ameliorating drugs like AZT are beyond the reach of all but the most wealthy. Many in Africa die of AIDS without even being tested for HIV 5 infection. The ELISA test costs about $5 to admin- ister. The Western Blot test, which is used to confirm a positive ELISA test, costs about $35. To put this in perspective, the entire annual health budget for Ivory Coast is around $10 per person, high for Africa. Education and Training. AIDS could ruin a nation's strategy of higher education. If AIDS reduces school graduates' worklives by 15 years, then the payoff to investment in education is greatly reduced. Policy- makers will face the grim question: Why spend money training people who are likely to die before the cost of specialized instruction can be recouped? This consid- eration applies not only to those who are infected but also to the entire cohort of young people likely to become so. Impact on Elite Groups. Elites in Africa, with greater access to travel and multiple sex partners, are af- flicted by AIDS in increasing numbers, with negative consequences for filling skilled jobs and for national economic productivity. Whether this trend will con- tinue or elites will change their high-risk behavior is unclear. Also unclear is the susceptibility of elites in other parts of the Third World. The urban base and risky behavior of most elites, however, leads us to speculate that the African pattern will be followed elsewhere. Impact on Military Personnel. Screening in many countries of soldiers and recruits for HIV has turned up a number of high rates of infection. This has implications for national security and for the ability of rulers to maintain their hold on power, mainly in Africa at present, but possibly elsewhere in time. Revenues From Tourism. Revenues from tourism comprise 4 to 5 percent of gross national product in Kenya and Thailand, and more than 20 percent in some Caribbean countries. In Haiti, tourism was virtually wiped out when the country became associat- ed with the disease, though tourists' fear of violence played a role too. Tourist visits fell from 70,000 to (b)(3) (b)(3) (b)(3) (b)(3) Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 Impact of AIDS on Security Forces In militaries where AIDS becomes widespread, readiness and effectiveness will be degraded. This will become apparent in some armed forces in Africa within two to three years, particularly from the loss of technical and specialized personnel. While the problem is most serious in Africa, some hard-hit countries elsewhere will steer important losses of personnel by the end of the decade. In Haiti, the military is a high-risk group, with an estimated 15 percent of active-duty personnel in- fected, compared with 2 percent of the general population. The infection complicates the search for healthy recruits-80 percent are turned down for poor health. Forty percent of beds in the military hospital in Port-au-Prince are occupied by AIDS patients, and four of the 49 Army doctors are infected. The epidemic threatens to overwhelm the alread inade uate Haitian military medical system. AIDS will not degrade the combat capabilities of other key countries before the end of this decade but will impose a growing burden. In Brazil, data on the infection rate in Rio de Janeiro, coupled with a serious IV drug problem, suggest a growing epidemic among recruit-aged youths. The Brazil- ian armed forces are aware of the danger and have incorporated general information on AIDS into military training classes. Due to fear of criticism from the Catholic Church, active measures such as condom distribution are not being pursued. In addition, legal challenges led to a cessation of testing of draftees and active-duty personnel. We believe health care costs will consume most of the military's medical budget within 5 to 10 years. The Indian Army has no screening or education programs despite a growing AIDS problem in society at large. Several divisions of the Indian Army are garrisoned near the Burma border where widespread infection is related to IV drug use. The use of prostitutes by troops and unscreened blood supplies suggest the epidemic will spread rapidly rough the armed forces. Screening potential conscripts in Thailand re- vealed the overall infection rate of 2.1 percent in 1990, but in three major northern cities the rate ranged from 6 to 14 percent. Recruitment, how- ever, will not suffer because of the large pool of conscripts. Confidential screening of active-duty soldiers suggests the Thai military is nonetheless concerned about AIDS. The potential for infection among high-ranking officers could lead to unex- pected leadership changes. By the end of the decade, the cost of AIDS-related health care could consume a third to a half of the military's medical budget The Soviet military has not incorporated AIDS prevention into its health program. When discov- ered, infected individuals are released from active duty, relieving the military of health care costs. Poor medical hygiene combined with a growing incidence of STDs and a lack of disposable syringes suggest that the infection will spread slowly in the security forces along with Soviet society. 6 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 �Te, 10,000 a year. Some of the sizable decline in Kenya's tourism is ascribable to foreign fears of AIDS. Thai- land's tourism is also threatened because its sex industry is a major attraction For these reasons, AIDS will be a huge drain on the economies of highly infected countries. Moreover, the epidemic will not alleviate problems stemming from rapid population growth. Development policies of the past several decades will be undercut or reversed, and aid donors will feel obliged to reexamine their assis- tance policies to determine whether to redirect their aid to�or away from�AIDS-ridden countries Political Instability. AIDS may in time undermine political stability in some countries as key officials succumb to the disease. In Uganda, for example, at least three ministers who were recently dismissed are reported to be HIV positive, and several other Cabinet members may be infected. AIDS will generate a search for scapegoats that will focus on leaders who fail to stop the epidemic. Leaders who themselves contract the disease may change their behavior drasti- cally owing to "AIDS dementia." Corruption may worsen as elites attempt to accumulate more wealth for their heirs at public expense in countries where this is possible. Leaders' illnesses may lead to power struggles among would-be successors Africa: Getting Worse The AIDS epidemic is at its worst in Sub-Saharan Africa. HIV infection was well established there by the early 1980s, and, until recently, little was done to slow its spread. We estimate that 7-8 million of the 560 million Sub-Saharan Africans are already in- fected with HIV, and by the mid-1990s the cumula- tive total probably will exceed 20 million. The number of AIDS cases will grow apace, well into the millions this decade The African Response: Too Little, Too Late In 1990, about $150 million was spent on AIDS prevention in Africa, nearly all of it coming from the World Health Organization's Global Program on AIDS and other foreign donors. However, even this modest level of effort is very recent and will have only 7 a marginal effect on the spread of HIV infection. Africans are not changing their sexual behavior fast enough to affect the course of the disease, even though the basics of HIV transmission have been widely publicized. Few African political leaders now put the full force of government into the fight, and fewer still share the medical professionals' sense of urgency. In Zimba- bwe, for example, despite high and rising infection rates, the Minister of Health downplayed the threat; only after his replacement last year�and subsequent death from AIDS�did the government embark on an aggressive prevention program. In Uganda, with one of the world's worst epidemics, President Museveni has wavered on encouraging condom use despite his acute awareness of the problem's seriousness Grim Future: A Changed Continent Infection rates are rising almost everywhere and are particularly high in cities and certain countries. Bot- swana, Central African Republic, Malawi, Uganda, Zambia, and Zimbabwe all have HIV infection rates exceeding 5 percent of the population. In a variety of subgroups in these and other African countries, infec- tion rates of 40 or 50 percent have been recorded. Nigeria, the continent's most populous country (120 million), has recently acknowledged that 500,000 are infected�probably a substantial underestimate. Without an effective vaccine or widespread behavioral change, the virus beyond 2000 is likely to infect 10 to 30 percent of the Sub-Saharan population Infection rates could reach 40 percent for young-adult age groups in many urban areas. Life expectancy at birth could be re- duced by 15 years or more. Some African economies will be stunted by AIDS, for reasons discussed above. In particular, foreign invest- ment in Africa, now only a tiny fraction of world investment, is likely to dry up almost entirely later Approved for Release: 2017/08/31 C06547069 ......Setre.t..... Approved for Release: 2017/08/31 C06547069 (b)(3) (b)(3) this decade in countries where AIDS is widespread. Foreign companies probably will substantially reduce their operations out of fear for the health of their personnel and in recognition of worsening perfor- mance of African economies. Will Africa's Experience Be Repeated Elsewhere? Conditions in Africa that contributed to the AIDS disaster included sexual behavior patterns conducive to the spread of HIV infection, high incidence of STDs, nonuse of condoms, governmental inattention to the problem in its early years, and contaminated blood supplies in some places. Wherever such condi- tions prevail, the African experience is likely to be repeated In certain Latin American and Asian countries condi- tions resemble those of Africa. There, the future course of AIDS threatens to follow Africa's path. Elsewhere, the outlook for the 1990s is better for two reasons: the slow-moving epidemic is in an earlier stage and conditions that govern the spread of AIDS range from somewhat better to much better than in Africa. However, the potential number of AIDS cases in newly infected countries is enormous; for example, Brazil and India together have almost twice the (b)(3) population of Sub-Saharan Africa (b)(3) Other AIDS Hotspots Around the Globe Thailand Thailand is the most AIDS-prone country in South- east Asia, according to the World Health Organiza- tion, owing mainly to widespread prostitution and IV drug use. Although Thailand's Minister of Public Health claimed the number of infected Thai at 27,000 early this year, some outside experts estimate a more accurate figure as 200,000 to 300,000 in a population of 57 million. Recent projections indicate that more than 1 million and up to 3 million could be infected by 2000. A study by the Thai Development Research Institute puts the potential earnings losses in the billions of dollars by the mid-1990s. Infection rates are highest among Thailand's half- million or more prostitutes (ranging from 10 to 40 percent, depending on the region) and IV drug users (25 to 30 percent). The rate among military conscripts is about 2 percent, with much higher rates (6 to 14 percent) among those from the northern provinces The government recognizes the problem and has launched large-scale programs to counter it, including systemic surveys for those infected, education efforts, and promotion of condom use. Critics say the program is too small and disorganized, but it appears that some behavioral changes have been made. Debate still rages over what, if anything, to do about the sex industry, which is a major foreign exchange earner. Prime Minister Anan Panyarachun, installed by the military junta, described prostitution and AIDS as two of Thailand's greatest problems. Brazil Estimates of the number of Brazilians infected with HIV range from 500,000 to 1.5 million in a popula- tion of 155 million. The spread of the disease will at least double the number of infections by the mid- 1990s Brazilian authorities lack an adequate picture of the overall problem. Testing for HIV infection is minimal, and the number of unknown, unregistered AIDS cases is likely to be many times greater than published figures. A large proportion of prostitutes in Recife and Rio de Janeiro is believed to be infected, and IV drug use is a growing urban problem. The city of Santos may have a 5-percent overall infection rate. Rates are reportedly over 50 percent in Brazil's prisons. Prevalence rates among new military con- scripts are not well established, since testing is infre- quent, but the rate is increasing and is apparently much greater than in the general population. Brazil's anti-AIDS policies are inadequate. The awareness program is small, and the program for distribution of condoms disburses only 6 million per year. The director of the national AIDS control division of the Health Ministry has shortsightedly downplayed the problem; commenting on WHO fig- ures showing Brazil to have the world's third-highest 8 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 --Setret,, 9 (b)(3 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 Figure 5 AIDS Cases as Reported to World Health Organization (WHO) Greater than 5,000 Brazil 17,373 France 'i4,449 _ Germany 6,176 Italy 9,083 -7 Ivory Coast _ 683 Kenya Malawi Mexico Spain Tanzania- Uganda United States Zaire Zimbabwe 1,000 to 5,000 Australia 2,494 Burundi 3,305 Canada 4,885 Colombia 1,285 Congo 2,405 Dominican Rep. 1,506 Ghana 1,732 1,000 to 5,000 200 to 500 Haiti 3,086 Cameroon 429 Honduras 1,133 Chile 255 Netherlands 1,68.3 Costa Rica 232 Romania 1,331 El Salvador 357 Rwanda 3,407 French Guiana 232 Switzerland 1,778 Greece 457 United Kingdom 4,454 Jamaica 201 Venezuela 1,061 Japan 374 Zambia 4,036 Mali 338 Namibia 311 New Zealand 229 500 to 1,000 Norway 208 Panama 249 Argentina 920 Peru 398 Austria 557 Senegal 307 Bahamas, The 599 Sudan 265 Belgium 852 Burkina 978 Central Afr. Rep. 662 Denmark 784 Less than 200 Ethiopia 636 Portugal 647 All other countries South Africa 764 Sweden 557 Trinidad and Tobago 736 Boundary representation ts not necessanty autnontaove 10 722542 (B0111_1) 7.91 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 number of AIDS cases, he argued that the figures overstated the problem since the number was small in relation to Brazil's population. India The WHO estimates 250,000 infections in India, though reporting from scattered locales suggests a number several times larger, possibly more than 1 million in a population of 866 million. Conditions in India point to a rapid spread of the epidemic: sexual behavior patterns conducive to the spread of HIV infection, high incidence of STDs and IV drug use, high rates of infection among prostitutes, and insuffi- cient safeguards to the blood supply. Moreover, with a nationwide literacy rate of only 36 percent, no doubt much lower among prostitutes and drug users, anti- AIDS publicity campaigns will not be highly effec- tive. The Indian Government does not recognize AIDS as a serious problem. According to press reports, a recent meeting of experts advised adhering to "Indian cul- tural values" as the best way of combating the disease. Foreigners are frequently blamed for trans- mitting AIDS. According to US public health experts, the official Indian attitude toward AIDS is consistent with earlier policies on STDs, which over the years have resulted in very little preventive action These attitudes are reflected in India's health care budget. In 1991, the government announced a three- year AIDS prevention program costing $1.8 million� .2 cent per capita. India's slow-moving bureaucracy, lack of funding, and lack of technical equipment will keep thegovernment's efforts lagging far behind the problem. This neglect probably will continue until AIDS cases and deaths exceed the hundreds of thousands. As with other epidemics, a death toll lower than this will not be clearly evident in a country of India's size and impoverishment. Therefore, we conclude that the Indian Government will not take meaningful steps to counter AIDS during the next five years. The epi- demic will most likely grow to Africa-like proportions in 10 to 15 years 11 The Caribbean AIDS is a major concern in the Caribbean, and the rate of infection is increasing rapidly. Haiti, the Dominican Republic, and The Bahamas are particu- larly hard hit. AIDS initially affected mainly homo- sexuals, but now it is well established among hetero- sexual men and women, as well as among children Caribbean governments are aware of the problem, but the prevalence of sexual behavior patterns conducive to the spread of HIV infection, IV drug use, and inadequate prevention programs point toward a con- tinued rapid spread of the disease. During the 1990s, AIDS in much of the Caribbean will proceed on a scale similar to that in Africa, with similar dire results for the economies of the affected nations In Haiti, government officials have not publicly acknowledged the seriousness of Haiti's epidemic, even though the country has the highest number of reported cases in the Caribbean, with infection rates now at 7 to 10 percent of adults. Until recently, officials refused to gather data on AIDS. An esti- mated 15 percent of military personnel tested HIV positive. The Dominican Republic has a far more active anti- AIDS program than Haiti, but infected prostitutes and contaminated blood supplies are still spreading the disease. The Bahamas has one of the highest infection rates, difficult to control for similar reasons. AIDS is also spreading steadily elsewhere in the region. Other Problem Countries Romania. AIDS is a major health problem in Roma- nia, particularly among infants. Hundreds of them received infected blood transfusions in hospitals. This type of transmission is far easier to prevent than sexual transmission, as it only requires improving conditions in the hospitals. Romania with consider- able international assistance is attempting to correct this, but the infection has already spread to the adult population through contaminated blood supplies and ria,L Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 sexual transmission. The scope of infection is poorly understood and prevention programs are only just (b)(3) beginning (b)(3) (b)(3) (b)(3) (b)(3) Soviet Union. The AIDS problem in the Soviet Union is relatively small�around 600 people with AIDS and about 20,000 infected with HIV, according to Soviet scientists. Primitive conditions in hospitals have led to transmission by infected needles, but that problem is now widely recognized, and limited efforts are under way to deal with it. Some hospital patients are now tested for HIV (though they are not always told the results). The disease will probably continue to spread slowly. Cuba. AIDS in Cuba will not approach the infection rate in Haiti or other Caribbean hotspots, largely because Cuba's AIDS control program is the most aggressive in the world. It includes nationwide HIV screening, lifetime quarantine of those who test posi- tive, and strict control of blood supplies and products. According to the Cuban Health Ministry in early 1991, 9.6 million tests had been given since 1986. (Cuba's population is 10.7 million.) These tests have identified 609 HIV positives, and of the 73 with AIDS symptoms 44 have died. However, it appears that testing for HIV-2 (a strain found in Angola) was not sufficiently rigorous Despite draconian measures, HIV prevalence in Cuba is likely to grow. Conditions are ripe: widespread promiscuity, high incidence of STDs, and the return of troops from Angola. Perhaps in recognition of this likelihood, the network of quarantine facilities is being expanded, with plans said to call for at least one facility in each of Cuba's 14 provinces. Mexico. Mexico is second to Brazil among Latin American countries in AIDS cases. It has a moderate but growing rate of HIV infection. The Mexican Government views AIDS as a serious public health problem and recognizes the threat it poses. But eight years of austerity measures have limited the resources available for combating the disease. The government has established a national council on AIDS, which conducts public awareness programs. Military leaders are wary of the potential for infection among soldiers. S�et Prevention Strategies The effectiveness of AIDS prevention strategies worldwide is difficult to assess. Worldwide publicity on AIDS has induced a portion of the world's popula- tion to protect itself against the disease, particularly in the industrial countries. In the LDCs, current programs may well be worthwhile in terms of lives saved per dollar spent, but they are extremely small in scale. These programs are very difficult to evaluate, because of data shortcomings and because their bene- fits may not be observable for years. The unanswered question is whether greatly expanded programs could reverse the long-term trend. Most likely, the question will remain unanswered, since anti-AIDS resources will probably grow only moder- ately during the 1990s. However, it is clear that foreign assistance without powerful national leader- ship will have little impact The developing countries that are taking steps to contain the infection are mainly those where the problem is already obvious, grave, and intractable. In other countries such as India, Brazil, Nigeria, and Thailand, where infection rates are sure to accelerate, preventive measures range from "totally lacking" to "inadequate." This is particularly troubling, since preventive strategies are far more effective when they are taken early in the epidemic The reasons for this nonaction involve medical tech- nology, politics, and cost: � In the early years of an epidemic, few infected people display symptoms. Without appropriate blood testing, sizable rates of HIV infection can go unnoticed. � The design and implementation of anti-AIDS pro- grams is an evolving field. Preventive measures are now familiar in basic outline, but none guarantees success. Indeed, behavioral patterns that cause the spread of HIV infection are extremely resistant to change. Another serious deficiency is the lack of 12 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 .'stbs[tL preventive methods designed for women. Govern- ments lack clear guidance on the effectiveness of alternative prevention strategies. � Even if dangerous rates of infection are detected, remedial actions are often politically difficult. Pub- lic awareness programs, for example, require a country to advertise its problems boldly�never an easy political course, especially in countries with sizable tourist industries. � An effective political constituency for action is often lacking, particularly in the early stages of an epi- demic when action is most effective. In the badly infected African countries, governments tradition- ally have not been very responsive to public wishes or needs, and there has been little public outcry to initiate strong anti-AIDS programs. � Full-scale prevention programs are costly. Free distribution of condoms, for example, would require a government to establish a permanent program costing upwards of $10 per year for each person in the targeted population. Even measuring the extent of the problem is costly: testing and analysis, costing roughly $5 to $10 per person, represent a major investment for health systems that are already meagerly funded. In Africa, even modest prevention programs can easily double the public health budget. A few countries, however, have taken action early in the epidemic. For example, China adopted an aggres- sive policy to identify infected individuals and to educate the population. Beijing recently hosted an international symposium on hepatitis and AIDS, even though China has announced less than 500 HIV infections and hepatitis is a more pressing problem. Likewise, after the first AIDS case was reported in Japan in 1985, Tokyo instituted universal screening of blood products and ended their importation. Japan estimates less than 1,700 infections, including about 400 AIDS cases, but the disease still poses a risk, and Tokyo will continue to use education and screening to control its spread. In Africa and the Caribbean, resources are lacking, and behavioral change on the scale that is needed has not occurred. In South America, political pressures for governmental action probably will increase during the 1990s, but dramatic spending increases are not likely to occur. The WHO now spends about $70 million on 14 countries, but much greater expendi- tures are required. For example, it would cost $460 million a year to provide condoms to Africa for an adequate program In Western countries, by contrast, far more will be spent. Political pressures are substantial for spending on research, public awareness, and health care. The economic situation is far more favorable too: not only is far more money available, the payoff per dollar spent may be greater as well. For example, Japanese researchers estimated that each AIDS case costs more than $450,000 in treatment costs and lost productivity and that a prevention program in Japan would there- fore be worthwhile, even if only a relatively small number of cases could be prevented. Implications of Research on Treatments and Vaccines 3 Even the most optimistic researchers acknowledge that an immediate breakthrough would not appre- ciably reduce the number of AIDS cases during the next five years. An effective treatment for HIV infection�even if discovered right now�would take several years to test, manufacture, and implement. Likewise for a vaccine: by the time everyone at risk was inoculated, it would take another decade for the epidemic to wind down. Treatment for HIV Infection Medical experts believe that no outright cure for HIV infection is likely. Viruses in the human body cannot be killed or removed by drug treatment, but the disease can be slowed by impeding their ability to ' This Memorandum makes no attempt to predict the success of the research efforts under way. Rather, it deals with the implications of ongoing research and what might occur if it were successful Even though the 1990s will bring an upsurge in AIDS cases, anti-AIDS expenditures will probably increase only modestly in developing and midincome countries. 13 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 multiply or incapacitate cells. Much effort is directed toward drugs, like AZT, that postpone the onset of AIDS symptoms. Progress along these lines is gener- ally expected to be incremental, with gradual im- provements in effectiveness and reductions in cost. These drugs, however, probably will remain too ex- pensive for widespread use in any but the richest countries. By comparison, penicillin at 10 cents a dose, is too expensive to treat everyone in poorer countries who needs it Vaccines Expert opinion varies on the prospects for a vaccine against HIV infection. Some think that the technical barriers may never be fully overcome, in part because of the high mutability of the virus, while the most optimistic think that the massive research effort might produce a useable vaccine within five years or so. Eleven "candidate" vaccines are in the early stages of testing on small numbers of people and may be ready for large-scale testing in two to four years. Once into a field trial, these experimental vaccines probably will need at least four to five additional years of development and testing before they could be proved safe and effective. Several problems will hinder progress. For example, Africa's high rate of infection makes it a good choice as a test site. But the strains of HIV prevalent in Africa may differ from those isolated in the United States. This suggests that a vaccine optimized for the United States may not be effectively tested in Africa. Testing in a country where AIDS is less prevalent than in Africa would require a larger sample and a longer trial period. At this early stage, the likely cost of mass-producing a vaccine is uncertain. If previous patterns hold, it will probably be priced much higher in the United States than elsewhere. For example, vaccine for hepatitis B costs about $100 to $150 in the United States, versus $3 or less in some Asian countries. The difference in price stems from the higher quality of vaccines pro- duced in the United States, plus costs that producers allocate to research and testing and to provision for product liability. This could lead to disputes over patents between US firms and their low-price compet- itors, an issue that the WHO has begun to address. A different vaccine may be required for each region of the world, because the prevalent strain of HIV varies from country to country. This suggests that pharma- ceutical companies may concentrate on the strains of HIV prevalent in the United States and Europe rather than on African strains that promise far lower profits. However, medical experts believe that in time all HIV strains will spread globally In the long term, an effective vaccine may be the best hope for a radical reduction in the spread of the disease. Based on experience, even after effectiveness is established, it takes many years before vaccines are used widely, particularly in LDCs. Polio and measles vaccines�effective and cheat. but still not in univer- sal use�are examples. Other Technical Progress The area of testing shows some promise. Cheaper tests for HIV infection would help in pinpointing the new infections, so that preventive measures could be better targeted. Tests that work in the earliest stages of infection (conventional tests do not) would permit more effective blood product screening. International Transmission AIDS has crossed virtually every national border in its global spread, and international transmission re- mains a significant source of infection and subsequent growth of the epidemic. For example, emigration from Haiti is believed responsible for much of the spread of HIV into the Dominican Republic, The Bahamas, and Jamaica. Many Cuban troops were infected in Angola. Thailand's sex industry has the potential to infect tourists from several countries, Japan for one example. To counter the spread of the disease and reduce costs of caring for infected immigrants, more than 40 countries now restrict the entry of short-term visitors or immigrants with HIV infection or AIDS. Several single out black Africans, and some deport infected foreigners. We expect restrictive measures to increase 14 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 AIDS and Immigration Laws and policies designed to reduce the foreign threat to populations from AIDS will remain controversial in several countries. Restrictions on immigration are aimed at reducing risks to residents and costs of caring for infected immi- grants. For instance, a Canadian study con- cluded that there would be a net saving in direct health costs if all potential Canadian immi- grants were screened and those found to be HIV positive were excluded. Critics charge, however, that this unfairly targets HIV-positive individ- uals and unnecessarily highlights AIDS among diseases. The Canadian study also determined that screening immigrants for cardiovascular disease would be even more cost effective than screening for HIV. It is likely that the debate over the laws and policies designed to restrict immigration on the basis of HIV infection will become more heated as AIDS cases and associ- ated costs rise during the decade. during the next five years, when the numbers of HIV infections in many countries will be much larger than they are today. US policies will also receive more attention as AIDS increases in countries that supply many of the immigrants to the United States. Implications for the United States programs in South America and Asia. Thus, the money goes where the disease is worst and where the demand for assistance is the highest In allocating funds, US policymakers will face the problem of how to choose between countries where the disease is already widespread and those where infec- tion rates are low but threaten to grow rapidly. The payoff to AIDS prevention assistance might be higher in countries where the epidemic is in a much earlier stage�Brazil, India, and Thailand, for example. These countries, however, have only recently acknowl- edged their AIDS problem and have not yet developed effective strategies. Indeed, the US Agency for Inter- national Development programs in Brazil and India are directed largely at persuading leaders that AIDS is, in fact, a major problem. The United States will face three basic foreign policy problems associated with the spread of AIDS in the 1990s: � Allocating assistance for AIDS prevention abroad. � Managing the testing and distribution of a vaccine in other countries. � Dealing with afflicted countries. What To Spend Where The United States now spends about $65 million annually on AIDS programs in foreign countries. Africa gets most of the resources, but there are small 15 For Africa, AIDS support will be an expanding part of the aid package during the 1990s. One study concluded that in five central African countries, AIDS medical care and screening alone could con- sume all foreign aid. Caribbean nations will follow this pattern, and later so will India. The rapidly rising incidence of AIDS�particularly in Africa�will at- tract concentrated, graphic media attention during the 1990s. Whether this will build popular support for large-scale relief programs�as has often been the case with natural disasters and refugee problems� remains to be seen. In a broader context, the experi- ence with AIDS demonstrates the importance of quick intervention, which may well be needed to deal with the other deadly but undetected viruses that now exist in quiescent forms and may spread in the future. Vaccine Politics Working out arrangements for testing and distribu- tion of a vaccine will pose numerous political hazards. It is conceivable that US efforts to protect people from AIDS could be tarnished, as countries haggle over the terms for allowing tests to take place among their people and demand more aid than the United States can offer. Rivalries among producers of vac- cine and disputes over patent rights might also slow Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 the delivery of vaccine. Similar problems over distri- bution of improved drug treatments probably will also (b)(3) arise. (b)(3) (b)(3) Testing vaccines could be a political minefield for the United States. As the WHO supervises foreign test- ing, conflict may arise as to which vaccines to test� those developed by and for the United States, or others aimed at European strains of HIV. Some African leaders are concerned that their countries will be used as a testing site and then abandoned once the results are in. They will probably make demands for the continued availability of any successful vaccine that they allow to be tested. Conflict may arise if the United States refuses to supply a particular vaccine on grounds that it is not effective. Other friction over who controls the design and management of testing is foreseeable. There will also be inevitable ethical issues on how to integrate prevention programs with testing. Many public health experts doubt that the capability exists to dispense AIDS vaccines on a worldwide scale. Some have suggested establishing an interna- tional corporation, funded by a consortium of indus- trial nations, to produce and distribute a vaccine at cost or below, with clear standards for assigning priorities for treatment. This approach would have the advantage of removing the United States from the focal point of criticism. In addition, companies capa- ble of developing vaccines would be given clear guide- lines on their patent rights; otherwise, it is argued, they may hold back on development efforts out of fear that these rights would be preempted by an interna- tional regulatory effort Anti-US disinformation may flare up in connection with the testing and distribution of a vaccine, particu- larly in Africa. Charges of racial discrimination, shifting unacceptable risks to Africans by testing vaccines on them, and distortions as yet unimagined are likely to be publicized. During the 1980s, various stories blaming the United States for the spread of AIDS were published, often instigated by the Soviet 'Tie4 Union. Such disinformation still crops up occasional- ly. Just before the Persian Gulf war, for instance, Iraqi officials playing to Arab fears asserted that US troops in the Arabian peninsula included "thousands of AIDS victims." Dealing With Decimated Countries AIDS threatens US objectives of promoting economic development in LDCs. Though we cannot quantify the economic impact of AIDS, it is hard to conceive of a developing country with both a serious AIDS prob- lem and a thriving economy. The badly infected countries will be radically transformed, with greatly reduced chances of developing. US economic assistance will become less effective in AIDS-ridden countries. For example, the rate of return to money spent on education will be less. Generating private enterprise activity and foreign investment will be more difficult. The question will arise whether these diminished prospects for effective- ness are a reason for more or for less aid. Whatever the scale of future aid programs, assistance to AIDS- ridden countries is likely to be spent on basic subsis- tence rather than on development projects. Military Basing and Access Issues These issues have quieted in recent years. Most governments seem satisfied that US forces in their countries pose little risk from the standpoint of AIDS. In early negotiations over basing rights in the Philip- pines, for example, numerous political and press state- ments claimed that US servicemen were spreading the disease. Such claims have largely subsided and are no longer impediments to an agreement In most countries, operationally deployed US troops are no more at risk from HIV than if they were stationed in the United States. As AIDS spreads, however, increasing portions of the globe will become less suitable as peacetime sites for US bases. 16 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069 Approved for Release: 2017/08/31 C06547069