SCIENCE - MEDICAL

• Document Type: FOIA
• Collection: FOIA Collection
• Document Number (FOIA) /ESDN (CREST): 05681015
• Release Decision: RIPPUB
• Original Classification: U
• Document Page Count: 2
• Document Creation Date: October 23, 2023
• Document Release Date: August 10, 2023
• Case Number: F-2020-01188
• Publication Date: April 5, 1949

pproved for Release: 2023/04/17 005681015
CLASSIFIDOWN
CENTRAL INTELLI AGENCY REPORT
INFORMATION FROM
FOREIGN DOCUMENTS OR RADIO BROADCASTS CD NO.
COUNTRY USSR
SUBJECT Science - Medical
HOW
PUBLISHED Weekly newspaper
WHERE
PUBLISHED Moscow
DATE
PUBLISHED 23 Feb 1949
LANGUAGE Ea.:elan
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DATE OF
INFORMATION 1949
DATE DIST.3-Apr 1949
NO. OF PAGES
SUPPLEMENT TO
REPORT NO.
THIS IS UNEVALUATED INFORMATION
Meditsidokiyllabotnik, So 8-820.(Information requested.)
NEW TIIICHNIVIES IN BEUROPAITY AND EPIDEMIOLOGY
N. Zeytlenok
Cand Nod Soi
Moscow
Many of the rrimary encephalitic and other infectious diseasee of the
nervous system are caused by virus. In the laot 12 years, Soviet scientists
have made great strides in solving this relationship. Progress in virological
rese9xch has been made possible by contributions of virologists, neuropath-
cr.mgiste, phyohlatrists, as well as by parasitological and epidemiological
institutions and clinics of infectious diseases.
New achievements in neuropatky were discussed at the Fourth Session of
the Institute of Neurology, Bowing" of Medical Sciences USSR. Representatives
of 37 Republic and Oblast centers attended. Among reports were those on tick-
bass encephalitis, chorio-encephalitie (peychosensory neuro-infectlon), chorib-
smedngitis, hemorrhagic fever, and papers were prevented on Undeterminei iAfe:-
tiohe of nervous systems.
Prof M. P. Chumakov, Corresponding Member, Academy of Medical Sciences
USSR, claims that in spite of various forms of tick-borne encephalitte there
is one fact common to all oases: studies conducted by virologists and immunol.
Meets resulted in conclusion that all strains isolated from various cases
belonged to one virus. This claim was supported by clinical, pathcmorphologi-
cal and experimental data.
Prof L. A. Zil,ber, Active Member, Academy of Medical Sciences USSR, die,
agreed with Prof Chumakov: Zil'ber supported the fact which clinicists have
leme nrovtanAwd; 111At thArm yew". varinum niininel forms of tick-borne encephalitis
in the different regione of the USSR:� Roweieri Zilliberye waa.no0101Ppar$md by
representatives of neurological clinics located in the back country and where
they have had excelicnt cppartdnity co observe tick-borne encephalitis under
natIval conditions,
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After consilerable discussion and argument, the following conclusion was
reached: that tick-borne encephalitis in man is of a single nosologic type
and etiology. However, there is great variation in the nosologic boundary,
along with vast differences in clinical characteristics due to living and
working conditions, period during which the epidemic occurs, climatic factors,
xooparaeitic nature of the country surrounding the region where the epidemic
has occurred, as well as changes in the macro- or micro-organisms brought
about by outeiee factors.
A report by Prof L. A. Omorokov suggested that tanners epilepsy wee a
eyndrame of tick-borne encephalitis. Reports by A. Y. Pecherkina-Sarapulova
(sulphur therapy), and Prof A. V. Pehenichnov (sulphur prophylaxis), shoved
the value of the indicated therapy. Members agreed to continue to seek an
effective preparation for controlling the dieease in acute and latent stages.
They aisio proposed to find improved methods for the etiological diagnosis of
tick-borne encephalitis.
There vas considerable dieGussion on chorio-encep'-alitie which appeared
suddenly among school children. The course of this disease is in two periods:
(1) when patients run high temperatures, and (2) which follows the first periel
after one to 4 weeks during which the patients show symptoms of paychosensory
disruption which prevents them from distinguishing eounds, ahapes and colors.
Mere appears to be a complete loss of depth perception during this second
period. The patients complain of headaches and indicate increased spinal fluid
pressure although the =position of the fluid is normal. Course of the
disease is intermittent and will came and go. Definite improvement is noted
in patients after spinal tape. Although the disease ie usually not fatal it is,
nevarthelees, serious.
Chario-encephalitis has been studied for only about 18 months, but in that
short time Soviet scientists have learned much about the disease. Reports by
various scientists discussed the of:I:elegy, epidemiology and clinical course
of the disease. The causative agent of chorio-encephalitis seems to be a
filtrable virus.
It was concluded that this farm of encephalitis is completely different
from the known forms of encephalitis and meningitis, including the mo-called
Economo's encephalitis, and is a new type of disease.
Various ideas were submitted regarding pathogenesie of thf,e dioease.
Chumakov's hypothesis, supported by clinicists and neuropatholajista, is that
patients afflicted undergo a degeneration of the vascular plexus in the cranial
sinus (ehoroid plexus). This results in increased spinal fluid pressure. In
same cases there is edema of the white matter of the brain and disruption of
function of the psychosensory ophere.
Prof G. Ye. Sukhareva agrees that infection of the vascular plexus is a
principal symptom in the genesis of this di-leave, but adds Jhat this infection
is secondary and is caused by the diffusion of the infection into the main
trunk of the brain with a resulting disruption of the isomeric functions of the
higher vegetative centers.
Discussions on hemorrhagic fever were conducted with representatives of
epidemiological, infectioniet and microbiological societies present. It was
stated that Soviet dectara were tte firat to describe this individual class
of acute febrile virus infections which have been generally termed nezo.rhagic
fevers. Intensive research on the causes of this diseaee brought to light
that the Omsk tope of hemorrhasic fever is caused by a filtrable virus.
Sources of this virus in nature were determined and an exact clinical picture
of the course of the disease was described. Soviet scientists have also
developed avaccinefor this disease.
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