(DELETED) FILE REVIEW

• Document Type: SPECIALCOLLECTION
• Collection: General CIA Records
• Document Number (FOIA) /ESDN (CREST): 00146168
• Release Decision: RIPPUB
• Original Classification: U
• Document Page Count: 1
• Document Creation Date: December 17, 2024
• Document Release Date: January 15, 1983
• Publication Date: July 31, 1975

C.
31 July 1975
1+IDIORANDLN FOR THE RECORD
SUBJECT:
'Pile Review
va.
The undersigned has reviewed three folders labeled
J These folders contain reports and miscellaneous correspondence
pertaining to a classified contract between the Agency and the National
Institute of Mental Health, U.S. Public Health Service. Under this
contract the NI?-1 conducted tests of various hallucinogenic drugs includ-
ing LSD. The stated purpose of the experiments was "to find synthetic
analgesic and antitussive drugs which are as safe or safer than codeine."
The file indicates this work was initiated by the Department of Defense
prior to 1951 and continued under Agency sponsorship from 1951-52 through
1962. Funds were initially transferred through the Office of Naval Research
and presumably this mechanism was used throughout the contracting period.
Funds involved varied between
2. Actual testing of the drugs was performed byNIMH personnel at the'
National. Institute of Mental Health, Addiction Research Center, Lexington,
Kentucky. According to documents in the file, testing was accomplished
on animals and human volunteers. The file indicates that the human
volunteers were patients at the facility in Lexington. The Agency project
renewal states that the tests "are accepted as standards for legal action
by the Committee on Drug Addiction and Narcotics, National Research Council".
There is no indication in the files that testing was done on unwitting
3. The file does not indicate what use the Agency made of the results
of the project. A report entitled "Final Progress REport" is contained
in file folder #3. This report summarizes the results of the project
through 1962 and states that the project will continue with NINH financing.
The report states that the goals of the project were realized. Among-the
results were the discovery of two useful analgesics (Darvon and Versid'ime)
and an antitussive (Romilar) as well as a number of other drugs which may
offer a substitute for codeine.