MKULTRA SUBPROJECT 47 (100 DOCUMENTS WITH PUBDATES FROM 550304 TO 64032 5)

• Document Type: SPECIALCOLLECTION
• Keywords: ATLANTA FEDERAL PENITENTI
• Keywords: BEHAVIOR CONTROL
• Keywords: BEHAVIOR MODIFICATION
• Keywords: BESSENT EWELL E
• Keywords: BIOCHEMICALS
• Keywords: BORDENTOWN REFORMATORY
• Keywords: BUREAU OF RESEARCH IN NEU
• Keywords: CENTRAL NERVOUS SYSTEM
• Keywords: CHEMICAL SNTHESIS
• Keywords: CHEMICALS
• Keywords: CLINICAL TESTING
• Keywords: DAVID HENRY P
• Keywords: DAVIS RALPH C
• Keywords: DRUGS
• Keywords: EMORY UNIV
• Collection: General CIA Records
• Document Number (FOIA) /ESDN (CREST): 00017445
• Release Decision: RIPPUB
• Original Classification: U
• Document Page Count: 202
• Document Creation Date: August 23, 2024
• Document Release Date: September 8, 1976
• Publication Date: March 4, 1955

� � �
�1!
� 4,,
I�XULTRA
Sq-Rt oject
- Description . . Date: Obl 1 gati ons � 1Npendi tures ' Balance
.
I
_Iftri.' _ - � _ �
.. ---------:---r_�,_-
J:,�!: ..,e-le / /7 - . - #S1). ...1.3 _. ___:.../d.e0P001_ _....1..:_:: _ _ ....At; e�eave-4
/ � .'. 3
dys-r...c..-
A
/ .... ._ /..... ./
pis.,E5P5 . �
.0400.
,
: .....
,
; . 1 ......
..
.1 . � � ;
I, 1. . .....:._:_____ _ . _.....,......: ! . ? i � ..
_51..:-.-......--����r...-. ..... '2-- .1 �:?_Peit-9 -5 d'a '.': __-- . I � 1
.
I ! � . i :
;
:
P . .
..� ____ ��_,�e/ .5."; el.; I erf ').....C- I - i
�
.4 ; : �
Se'��.,..C.,' ...: �C� 1
i
.. .
7.
-t�
;If
_
. .� I
-
� - 4 04.4.
�
!
; i I
- i i � �I.i
-1
I . . I
LltnEts
. i
. . 5 . .
I . . � .. ���� .
I
....._ ...._ _ ... . t. .
-
r-
-
-Project PXULTRA, SUbproject 1e( -
Date initiated: 24 Varela 195
Date tclresi 1 Jul. 19-62
runds-current yiqu.: 4301740
Funwal Pharoacological and clirdcA-teattns in anirals and volunteer*
of cheolcals and bio4.seicalswhich alter-behavior. 1'i4vides Consultation
on sTecial prOble7,5 of 'ISO interest.
vIr
TXR
Status: Study complet-ed on thres:hold doses of ISD-25i'A cethod for
exilloring antci!ea of this drus; by otheregents. ShAit hp_s been-
Initiate-4 to evaluate cccwound_prolucing'arrnesia and having an alcohol
3ike effect on behavior 1.411_bestarted.--Evaluation oeeffects of
eodbiratioa of drugs of interest-to TSD is 0 completet
1.
. �
-
"44
sir
%.)
- - -
N.S \\/
Is% N.4 ti _el
t� _
�
N
, �_ .
� � I
g .Z1 Z`Thl irlisA �\
I
%1 - 4- tirl
SVsa. 4_4\ _1,4_ ,_7".�__,_ 11.____ -_.__
�.1
t it
.....
-+
f
Min 21rrory
BUREAU OF RESEARCH IN NEUROLOGY AND PSYCHIATRY.
CIO NEW JERSEY NEURO PSYCITIATRIC INSTITUTE
BOX 1000
PRINCETON. NEW JERSEY
NUMFMRY OSMOND. MRCS. LRCP. DPM
DmecTCA
Dear
�
t-
15
Attached is our 1963-64 reportfa.nd proposal for continued
research support by theafipta-ZZ:), for the coming year be-
ginning June 1, 1964. We hope that the report and the proposal
meet with the Beard's approval so that you can advise us positively
when you visit us in the near future.
C-
shall be in on- Saturday and Sunday, May 2nd and
3rd. I can report in on Friday, May 1st in regard to a possible
conference if this is necessary.
Our financial report for the present grant year will be sent
shortly after June 1,1964.
March 25, 1964
CCP:tt
enc.
Yours sincerely,
Carl C. Pfeiffer, Ph.D., M.D.
Head Section on Pharmacology
�
Date .5 Septe b r 1963
BEHAVIORAL ACTIVITIES SUPPORT
DB Branch__ _ Category__Behavioral Control Materials (Via )
(formerly Jib)
- Project N. A. Item C1assification N. A.�
Project Crypto
Branch Project No
Con tractor
MKULTRA
LA.
Crypto C1assficationUnclassified
Project Engineer
Dr. C.C. Pfeiffer
Contract No. Subproject 47 Task N
4
N. A.
Type of Contract _ MICULTRA Date Initiated March 1955
Cost . 000. 00 Completion Date Continuing (renewed April
1962)
Purpose: For pharmacolec,0ical and clinical7lesting in animals and humn:-
volunteers of drugs altering behavior.
Status: �
Clinical testing programs involving evaluation of special-
ized materials are proceding according to plan.
R'equirernent:
Internally generated in TSD.
"":-`
*._:..*." .! �
)
XI .
FINAL
-_. �
Date _
31 October 196
BEHAVIORAL ACTIVITIES SUPPORT
BrnchPi Category Behavioral Control Materials
(formerly lib)
Project Title N. A. Item Classification__
Projer:t Crypto MKULTRA Crypt� Classification _ Unclassified
Branch Project No.
N. A.
Project Engine
Contractor__ Dr. C. C. Pfeiffer
Contract No Subproject_ 47
Type of Contract 11KUL'I'RA
r 43Eir
TaskNo
Date Initiated
r
_ .(V1a).
March 1955
Cost_ Completion Date Copt inu ing___(renewed April 1962)
Purpose:
For pharmacological and clinical-teSting in animals and human
volunteers of drugs altering behavier.
Status: Satisfactorily terminated. Contract replaced by MKULTRA 144
Requirement: ; Internally generated in TSD.
(gIlhon Filled 1N)
. SWMIC UY 1 yoaCHER NO. (Finance moo only)
,...
ACCOUNTING BY INDIVIDUAL., 1�,�..../v
�I-an_ .., oubD1-e.t l'47
FOR A)VANCE.
PERIOD OF ACCOuNTANO
TE: Follow 7 etructione on
F 0 I
-e. "b
.TO
?I 4.04, NO'
. REC Prs I,DASRUPSEvENTS
I. Cl.$VI ON NANO SEGIPtMIN OF PC41100 s .V=4, OAT( ON OH ArooNT
V ,.
1 1
. EEE4 OAT
!Tors
OCsON4PTION
.. ' ''' crttfIcation
' � A
I
I ToTAL Cxe sEs 2c:21140(..09.0C
3a
4. 0111FIJNOCO NEN r TN CIA'S* 'coerce
�
d s. ti4s1.1 ON NANO CND Or Pc*100. ,
TOTAL
TO ACCOUNT FOR
WPAAWITTAW 1 :TOTAL ACCOUNTEO FOR is 2r OCA.4.00
I CERTIFY
FUNOS ARE AVAILABLE I1 I APPROVED: I certify that rho eapendievree lieted horoen acd,
LiGATION FNCNC
p...........................4.1.7.��....................2
HO.
C A E ALLO mENT NO.
OATC
1
5,GNA 401E
' CT'
Oe APpolOyING OFFICC5:1
1 H I !porn
1
)0
on any attachments were incuerod fee official ours
of a confidential Aature. that paymont or
crodit therefor hos not boon roceirod, and that
this accountInd Jo true and. I.
I 547( I
SIGNATURE OF NOTNONiZING OFFICER
I CfIrTIF FO FOR PAYMENT OP C EDIT SA
NATURE OF PATE(
OAT
SIGNATURE OF:CERTI.PVIING OFFICER
'
SPACE BELOW FOR EXCLUSIVE USE .0FIFINANCE DIVISION
PREPARED NY
1
'
REVIEWED. eV
, '
VOUCHER NO. 3.12
.y.--?ESCRINTIO � ALL OTHER ACCOUNT3 13.33 314.30 A0.4211 A
1
, 1 '
NO.1441 47.S;
54 57 Selo 67
-
614.70[ 141.641
'
20.33
T/A No.
STATION ,
COOE ExPENEI
PAY
OeLlak
NEF. NV.
53:
GENERAL
ALLOT. oft
ACCT. NO.
cosy
OvE '
DATE '
AMOUNT '
.1 DESCRIPTION: � ADVANCE Acc000rs 13.27
P.O. NO.
,1 CODE
"GP. to. I ' '
,
0
PEN.
LID.
..,
A*14**.P
CA
YR
LEDGER
ACCT. NO
62.67
CA. mO.
001ACT
1
0243
,,OJCCT MO� PVf ,
S CODE
l!F!:
AMA. MO.
o sor.00. C1.01611
OCSIV
4646IT
MI firr4 I 1 I
III 111 II 11,
I
I
I
,
I 1
I I
. -
I I
11/0. If 4 II111.
I I 1 t I i III III
'
1
I.1
4
1
I
1 i
VII �
I I I V II i
'
I
-
1 .
I
OIT TV ITT I I (
1111 1,1 i It I I I
I
V TTI-1-111 I V I I
I i I 1 I 1 1 I 1 II I
I
i
7
7
1 I
S
TOTALS
1 1
i
1
F0044 20.)
6.61 tt.t4 VOA, A11111000 flOITIONO.
-514R'Ff".
41:
12MMPft
( When Fi11d ti,)
�Aer
iNSTRUCTIONS
:f funds; in the form of other than U.S. Dollars were on hand, received, or disbursed during the accounting
period, all pertinent data, i.e., rate, method or acqutsition, etc., must be shown. if advances have bees
made to third parties, enter the total of such advances outstanding at the beginning of the accounting period
on line la.
. If more space is required to explain receipts, prepare receipt form, number and attach hereto. In every ase,
completely identify the source of receipts.
. Attach a voucher for each expenditure and assign a number thereto innumerical sequence. The voucher may be
the receipt obtained from the payee., When .a receipt is not obtained, prepare a certificate: and attach as a
voucher. When space on form Is I: not sufficient to. list all Vouchers, prepare a listing on a separate sheet
and enter the total under item 3. If advances :to third partiesare outstanding at the close of the account-
ing period, attach an itemized list and enter ,the total on line 36.: 1;
;
4. Final credit v1.l not be given for disburseMents:::Uhich are, advances tolbe:aCcounted for. When accounting
for advances are 'obtained, list as, expenditures or Inerund or CashH as Appropriate.,
-1...,�11,1 :
5. Vote. receipts entered on the line "Total to Account For7. must Agree with the total disbursemen sentered on
the line' followlng, "TOtaL AccoUnted,For.!'
: �
f
--
V� $25,000.00
: s s; � 1.!
:riy
- ���:. �
-
25 July 1963
:
it-ttt, of New Norm
BUREAU OF RESEARCH IN NEUROLOGY AND PSYCHIATRY*
CiO NEW JERSEY NEURO-PSYCHIAIRIC INSTITUTC
SOX 1000
PRINCETON. NEW JERSEY
I.
7fi
Aay 24, 1963
Dear Dr. C-
I have been informed that your granting committee has again
agreed to support our research for-a-one year period beginning
June I, 1963 and extending until May 31;-1964. On behalf of the
New Jersey Mental Health Research & Development Fund, Inc. and my
co-workers we wish to thank you for this expressed confidence in
our originality and productivity.
Attached you will find a succinct summary of our expenditures
on the 1962-63 grant. Exact detailed expenditures are available in
the office of the Fund.
Best regards.
Yours sincerely,
Carl C. Pfeiffer, M.D.
Head, Section on Neuropharmacology
CCP:tt
FINANCIAL REPORT
June 1, 1962 to May 31, 1963
Annual Grant to N.J. Mental Walth Research & Development Fund
Research Project of Car1 C P1ei1fer, Ph.D., M.D.
Receipts
$25,000.00
Expenditures
Salaries
$19,635.54
Wages
3,546.49
ExptIl Subjects
878.00
Travel
939.97
Total
$25,000.00
I certify that ce-v7it,
Fatisfactorlly
inctIrred cn oflio,
fr
-0i.r!Al5 have teen
� 4-r PlptglitUrea-
'neSS
Dato:L2s �c''
iv V 13
Carl C. Pfeiffer, P .D., M.D.
e
Henry P. David, Ph.D.
Secretary-Treasurer
N.J. Mental Health Research
and Development Fund, Inc.
Branch_ *a_
Project Title N.A.
Project Crypt�
. 21 .7.A.Tv-.:'y
Category ,chavior Control
Item Classific ion______ N.A.
�
( )
IIKULTRA Crypto Classification_ Unclassified
-
Branch Project No. N.Lib _ Project Engineer
Contractor_
Dr. C. C. Pfeiffer
Subproj 7
Contract No ect
Type of ContraeLYKLIPTRA .
Cost_
Purpose:
Status:
$25,000.00
Task No.
N.A.
Date Initiatect Varch 1955
Completion Date -
r ntinuir.L: (renewed. April l9C2)
For . pharmaeolocical and clinical testinL in animals and human
of drugs altering behavior. - -
'Clinical testinG prozrams involvinG evaluation of specialized materirls
ere ITc.ceding according to plan.
YLNT SOURCE: Internally gens,ated in TSD.
-
�
c
Branch 50 Category Deh
r Coa roi
- Project Title 4 . � Item Classification 0�1"
(11b
Project Crypto LikUl...TRA
,.... Crypt) Classification_ Unclassified
-.,
n`
Branch Project No i I. A.. : Project l ngtneer 454Vtle-t"Zar
Contractor Dr- C. C. Pfeiffer, New Jersey Neuro - Psychiatric lastitute,
Princeton, New Jersey
Contract No Silbp roleet Task No 11.A.
Mr:ULTRA March l9S5
Type of Contract Date Initiated_
Cost $2.5.00C) Completion Date Coatinuing (renewed April '62
Purpose: For phamaacological aal clinical testing In oairnals anihurriaa
volunteers of drugs altering behavior.
Status::: V, ork schedalcd for FY 6Z has beta completed and a oatifactory
final report has Leen submitted..
NEW JERSEY MENTAL HEALTH
RESEARCH AND DF.VELOPMENT FUND,
Tnisteee
JOSEFII M. TOBIN, M.o.. � PAUL IIAUI�k, M.D., Vice Ci.erraten � HENRY P. DAVID, PH. D., SeN.:11AS rteaStinat.
V. TERRELL DAVIS, M.D. � MAURICE0 }COTT, Pn.D. � DOUGLAS It MAtNEIL � LLOYD W. McCORK Pa D.
Address Co. .pt.ridence.to:
1 re.nzy p.Davi'd. Pit. D.
Secretary Tf aitSliter
1 PI La no
Trenton S. N. J.
June 1, 1961
to May 31, 1962
BUREAU OF RESEARCH IN NEUROLOGY AND PSYCHIATRY
SECTION ON_PRARMACOLOGY
c/o New Jersey Neuro-Psychiatric Institute
Princeton, New Jersey
RECEIPTS:
November 1961 -
$ 15,370.00
February 1962
_15,370.00
Tot4i Receipts
$ 30,740.00
EXPENDITURES:
Salaries & Wages
$ 10,356.13
Travel
1,476.80
Permanent Equipment
16,794.62
Consumable Supplies
1,771.66
All Other
340.79
Total Expenditures
$ 30,740.00
I ha!yr, ry.,,:ind and appmved the submitted
hief
&teal Branch
,
Henry P. David, Secretary-Treasurer
()/1'.
.0.'.. A e :�C' 1,,A a' ' '....-a... � r .----/
j ,
-Carl, C. Pfeiffer,
Principal Investigatori
Head, Section on Pharmacology
Contr;but;ons afe t;ble 1t Federal imort,r Tax Purperea.
- For Ssrvi
�
� nivoicz
cFariv"efipTOR3''7''''
97-
4)4,8 0.c
13
(1) it is bareby certifiedithat7-this id Ineice: snpl:fira. to
Sub-project Fo. of ENWATA,-that perforinanc 13 rt savis ory�
=
thnt der-Ideas are 'Olin& aecmplicha&ine-e-Oda-nce with Eutual EZYCZ-
. meats, that a detailed egenan-of-the payoents snd receipts is ol file
In TSD/BB, that this bill Is just end correct and, that paypent V4areof
bas not yet teen nade.
rte:
--it3 April- i9
ehili,
(2) It is hereby certifel-tlInt this Invoice applies to Sulepreset
of XKULTak vhich no duly appreVed; sal th7.t the pzojeet
171-faig tarried out in decor&Ince with,ths veiiorandua of 13
1953 from the DCI to the DD/A, sad the extension of this nuitsty
in subseqUent msnoranla.
De'
issesrza
�
Chief, Ts
RECEIPT
Receipt is acknowledged of Treasurer's Check No. 190924, dated
May 3, 1962, drawn oh thelittelr
45:14..in the amount of $25, 000. 00, payable to
�r.ret.--keg
Receipt is also acknowledged of Treasurer s Check N�Y400026,
dated May 3, 1962, drawn on the tal
in the amount of $1, 000.00, payable t
DATE�
Alt
V*.
L-1-7---9
s:
Z3 April 196Z
MEMORANDUM FO Chief, Finance DIV1311)11
"1, TSD/Budget Officer
SUBJECT* hilKULTRA, Subproject 47. Invoice No. 13
Allotment No. 2125-1390-390Z
1. ravolce No. 13 covering the aboYe subprojec is attached.
Payment should be made_as_follows
Cashier's check in the an4nt of $Z5, 000.00 -
erawn on a
hank.
Cashier's chock in he an-tount of $1,000.00 drawn
on a
bank.
Chocks should be made payable to the
zaz2
Z. Please tory/2.rd the checks to Chief, TSD/Biolozical Branch
through TSD/Budget Officer by IS May 19621
3. This is a final invoice. However, silken is anticipated .
that additional funds will be obligated for this project, the files should
not be closed.
Yi.t 00>_
/, 000. e)4
CHECKA______ IN THE AMDIJNTUF
,
RECEIVED.
Attached:
Invoice & Certificatims
Distribution:
'Orig. & Z Addressee
1 - TSD/FASS
2 - TSD/BB
TSD/13B:
24 fl
1I62
1 I*AT
9/ a -5 9 3
ertle4 , I _ _ 0 a
AL:.1.-.;:rr,
�
Lttte: Li April
1....Y3P'ANV1-i FOR: Ile.Cctr�r
Etlaizur
: Fir,hee Edvislon
: b'ojt 37
tbe av'thority 1.-,r;?..Lnerc.. ti r.ieatei 13 Apr11 1953
:Cron th LC to the IDIAi e_td tle_oxter4.ion Of this autliority fix sa4---
V.Z"�0_11nt� rktz-kortir;Cla) SPbto7ojer:_t_ 41 i� approved tod � 000.00 - -
of the ov.z.,r-$.11 Project itAtls- Lave 11.1.1 ohlIce.ted to co-viz
cul.%Itroja:tes ena Cloula te
OVF FOR OPLEIAT1ON
0/ 11)(iT3:
� o 390-3904
ft
aagall,
Cir7./.74,
T3P/Biolo,-Jr.6.1 Bmnch
_
Chiel, TSD
_
Crir1C: 2 - Aclexcssele
I/1 TSD/FASS
1 - TSD/BB
I C.: 7:F :It 7 F. t / "E
ire 1...:14.10:11/1.41E1 _
p.1.0 IF, -
_
,c--z #.3 C:liCit
DRAFT
12 April 1962
MEMORANDUM FOR: THE RECORD
1.
MKULTRA Subproject 47
�
The purpose of:this subproject 47 is to provide funds to continue
a research program 'being carried out by Carl C. Pfeiffer, MD.
2. The nature of the investigations to be carried out under the
direction of Dr. Pfeiffer enc mpasses pharmacological and clinical testing
in animals and human volunteers of chemicals and biochemicals which alter
,behavior. Certain phases of other problems of interest to TSD will be
investigated.
3. Dr. Pfeiffer is located at the Nevt Jersey Neuro-Psychiatric
Institute in the Bureau of Research in Neurology and Psychiatry, Princeton,
New Jersey.
4. The funds for this project will be transferred using the
'*-t/I:trses a cut-out.
5. The cost of this program for a period of one year beginning 1 June
1962 will not exceed $25,000.00. To this SWII must be added $1,0.00.00
representing a 4% service charge to th
s, making the total amount $26,000.00. Charges should be
made against Allotment No. 2125-1390-3901.
6. The New Jersey Mental Health Research and Development Fund
Inc.. who administer the grant have agreed to provide the VrIT.
to: EIJI' 'MAL
17 o : 87 75
te 1971
� - .
with a summary accounting on an annual basis of all monies received from
the
to the
They have also agreed to return any unexpended funds
s soon as possible upon the close of the grant year.
. �
7. Tile requirement for a six months' informal accounting on the part
. �
of the principal investigatOr is waived.
8. Title to any permanent equipment purchased by funds granted the
New Jersey Neuro-Psychiatric Institute shall be retained by the Institute in
lieu of high overhead rates.
9. In connection with travel under this project, it is agreed that the
�
Agency will accept the travel documentation and accounting which conform
with the practices of the New Jersey Mental Health Research and Development
Fund, Inc.
10. It is agreed that technical reports reflecting the progress of the
research program shall be submitted at mutually'acceptable intervals.
11. Dr. Pfeiffer has signed the Memorandum of Agreement and holds a
TOP SECRET Agency Security Approval.
C ief,
TSD Di ogical Branch
APPROVED FOR
OBLIGATION OF FUNDS:
Date:
Che'el
2 API11962
Distribution:
Original only pc,?;.,-1�45,36,y�e:4
Attachment: Proposal & Budget
PROPOSAL:
�
RESEARCH PROJECT APPLICATION
Grant Period June 1, 1962 through May 31, 1963
The testing inanimals and humans of chemicals and biochemi-
cals which alter behavior. .
PLACE: Section on Pharmacology
Bureau of Research in Neurology and Psychiatry
New Jersey Neuro Psychiatric Institute
Box 1000
Princeton, New Jersey
PRINCIPAL INVESTIGATOR: Carl C. Pfeiffer, Ph.D., M. .
C,
CO-PRINCIPAL INVESTIGATOR: M.D.
GRANT ADMINISTRATOR: New Jersey Mental Health Research and Development
Fund, Inc.
1 Jill Lane, Trenton 8, NeW Jersey
Henry P. David, Ph;D.I Secretary-Treasurer
INTRODUCTION:
Our research efforts have received local attention and approbation
during the past year so that we now have excellent rapport with the staffs
of both the Institute and theB6rdentown-Reformatory. We now have 10
volunteers per week from the latter and we have a Clinical Investigative
Unit which will house 80 schizophr lies (present census 45 patients).
Current Status of the Pharmacology Unit
The laboratory is still undergoing minor construction, but material
progress has been made in the past year. The section for animal screening
and conditioning is complete. The sections for animal neuropharmacology
and clinical pharmacology have been constructed and put into operation,
andan electronic workshop has been set up. All these units are actively
at work in human and animal experiments as outlined below. The T.,.nilities
WARA'JINcTtJO110E
SEN
.S0'!RCP�INkOLVED
r) �
of the clinical unit---experimental ward---are nearing completiOnl and
are already in partial use. Still in varying stages of construction are
the biochemical pharmacology and medicinal chemistry units.
Personnel: Sin de the last report, the section has been joined by Drs.
C,
AileZrand as planned. It is anticipated that two to three
more investigators at the doctoral level will be needed, probably one
more clinical pharmacologist, a medicinal chemist, and a biochemical
pharmacologist. Two engineers have been employed for design and con-
struction of new equipment and six lab assistants are now fully trained
to their various jobs.
Human subjects: Liaison with:NaZe'rseifState Reformatory -,Bordentown
has been excellent, and a full complement of volunteers from that insti-
tution has been freely available. This group may be a better group for
this kind of research, since they may be closer to the normal population
than were the Atlanta prisoners, the latter being recidivists and older
than the BOrdentoWn'group. In addition other human volunteers have
been recruited, including female subjects, so that the population of
"normal" subjects available is now much more nearly representative of
the population at large. In addition, it has been possible already to
begin explorations with the psychotic patients from the experimental
ward, and some interesting results are already forthcoming (see below).
Equipment: 'Since the last report, the section has obtained a stereo-
taxic apparatus, a Grass Model III EEG and a Sanborn 2000 magnetic
tape Data Recorder.. In addition, we have constructed two new integrators
for quantitative EEG; these are modeled after the DioNocki Integrdtoe;
but due to some circuit changes are more linear', and have the advantage
of using all Ur_A-Alade parts, so that maintenance is simplified. Two
more integrators are under construction which will albw simultaneous
1;4-f �:-.7.;4C
INVa
-integration of four leads, one from each lobe of a hemicranium. Also
under construction is a quantitative spectral analyzer for use with the
tape recorder in analyzing scalp EEG of humans as well as electrical
measurements from implanted electrodes in cortex and deeper structOres
in brains of animals. Data will be entered on punch cards and processed
by a digital computer. Target date for beginning calibration and stan-
dardization is June 1, 1962. These new approaches allow determinat5on
with great accuracy of effects of various classes of compounds and the
interactions of such agents.
A Barber Colman gas chromatograph has been installed and a technician
is being trained to operate it. Thir makes possible correlative studies
of changes in brain constituents, changes in behavioral state, and electro-
physiological data. This method is far more sensitive than previous
techniques, and allows accurate measurements to be made from much smaller
brain fractions. A Beckman pH meter-and microburette have also been
obtained for study of cholinesterase activity, since it appears that
psychotomimetic effects frequently if not always involve atropine-like
drug action (Pfeiffer, C.C., et al. Neurology 9:24925O, 1959)
Recent and current projects: These new techniques, together with the
unique availability of human subjects both normal and abnormal, make
possible a wide range of investigations on any class of compounds with
action on the central nervous system. These can begin at the Most basic
level and move progressively to a level of sophistication beyond that of
ali7.cst any other setting. Sore idea of the directions currently being
talen are indicated in recent and current work. Enclosed a e-reprints of
publications during the past year. The following are also accepted for
publication and will appear in the next few months:
-Sc
a$, and Pfeiffer, C. C. Use of normal subjects
for testing drugs (Upjohn Conference), Clin Pharmacol & Therap.
�
At the Federation meetings in this month,
will report on,
and and Pfeiffer will report on, .
quantitative eleetroeneephalographic analysis of the'effeets of lysergic
acid diethylamide (LSD-25 and d-amphetamine in man. At
and in Munich
Dr. Pfeiffer is giving a paper on, Further quantitative eleetroencephalo-
graphic studies of the stimulant effects of deanol and d-amphetamine in man.
-------------------------
Abstracts of these four papers are enclosed.
In addition to the above which are ready for formal presentation,
the following are under_way: A number of tryptamine derivatives are
being explored for psyehotomimetic and other effects; 4-hydroxy-a-methyl
tryptamine, 4-methyl-a-methyl tryptamine, 64ydroxy-N,N-dimethyltryptamine
(The di-methyl analogue of Szara's compound.),. prolyltryptamine, psylocin,
and acetyl tryptamine. Results will be reported as they accrue. The
central actions of,y-aminobutyrie acid are being indirectly explored by
investigati;g y-butyrolactone and y-hydroxybutyrie acid. Unlike GABA,
these compounds readily cross the blood-brain barrier, and the:latter is
a potent hypnotic agent and about as active and positive as is chloral hydrate.
) has reported an abnormal EE6 response
�
to intravenous thiobarbiturate in schizophrenic.s. Our quantitative method
shows no difference as yet in response between normals and schizophrenics.
to the intravenous injection of thiopental.
� � �
SINVOL
5.
Research Proposals
n-the-light of the above, the following are planned for the co min year:
� Screening of tryptamiqe compounds in animals and man for hallucino-
genic action.
� Completion of the study of the use of riboflavin as a trace chemical
to prove the ingestion of medication in a clinical setting.
3. Further studies on the use of phenoxybenzamine and other adrenergic
blocking compounds as antidotes to-LSD-25.
4. Further refinement of the use of quantitative brain wave studies to
diagnose schizophrenia and to determine the action of hallucinogens.
5. Selection of one or more of a series of stimulant diamines for chronic
toxicity studies in animals so that they can be tested in normal human
volunteers for possible stimulant action.
6. A search in brain extracts of rabbits treated with Tofranil (imipra-
mine) to determine if any stimulant amine accumulates as a result of
degradation of the drug molecule in the body.
7. Determination of the anti-cholinesterase and aminoxidase inhibitory
effect of the stimulant diamines.
8. Assay oface0:holine content of various portions of the biain after
prolonged administration of deanol.
9. The assay in man of an intravenous analgesic solution composed of
morphine and choline or morphine and carnitine wherein the. pharma-
cologically neutral quaternary compound prevents the engagement of
SE!
SOURCEs/us.
peripheral receptors by the morphine.
10._ The use of stimulants to prevent the blocking of conditioned
behavior.
11. The use of parasympathetic stimulants and methylatropina_to interrupt
trained behavior.
12._ A study of practical drug antidotes to Atropine-14k� compounds.
13. Careful study in noraal_man of
-
A. VIL'iTIWsynthesizO compounds -
B. CompolLids supplied by the.'.
. Biochemicals purchased
Note: For elaboration of methods see the 1961-1962 proposal.
t 'PFLUG *:CE
v6LVE0
_
SOURCES
Research Project Application - Pfeiffer and
Requested Budget
June,), 1962 through May 31, 1963
Time
Amount
Principal Investigator, Carl C. Pfeiffer�Ph.D., M.D..
5%
$ 4,000.00
Co-principal Investigator, tatartf44. D
25%
3,000.00
25%
None
Senior Research Scientist, M.S.
2 7,000.00
Neuropharmacologi.st,4tUaZ-41CVA4P1-1.D.
50%
Technician
100%
4,80).00
Secretary,%7
25%
1,300.00
Stipends, Numan Volunteers, 50 x 10 x $3.50/wk - ---
1,750.00
Equipment
850.00
Consumable Supplies
1,900.00
Travel to Scientific Meetings & Conferences
950.00
TOTAL $25,550.00
In lieu of overhead. the New Jersey Mental Health Research and
Development Fund, Inc. will retain title to any equipment which may be purchased
under said grant.
vvi mnp ricE
-
ND tiE Tft6ef INVOLVED
117
At& of *its 3irrqg
BUREAU OF RESEARCH IN NEUROLOGY AND PSYCHIATRY
C/O NEW JERSEY NEURO PSYCHIATRIC INSTITUTE
BOX 1000
PRINCETON. NEW JERSEY
JOS 1,1 M. 7013IN. M. D.
DIRECieR
Deart=1
���� I
March 2, 1962
Attached you will find interim report of our expendi-
tures from the Z04430t4j(4,14 from the period beginning
June 1, 1961 and ending May 31, 1962.
This brings to mind your promised trip to see our labora-
tory and the progress in our research efforts. We hope that
the month of March will afford you time for such a visit since
we now have much to show you.
With best regards,
Yours sincerely,
I
CCP:me
Att.-(1)
.-
/
.�
Carl C. Pfeif.ter, M.D
Head, Section on Pharmacology
..�
Personnel Salaries
and Wages
$1 148.40
1,070.80
665.40
3,492.00
130.37
$6,506.97
Period Ending March 1, 1962
Travel
Permanent Consumable
Equipment Supplies
Other
65.09
$1,182.44
3,418.78
$ 447.30
205.55
$ 45.35
4.00
102.94
1,259.65
147.71
56.39
304.61
773.83
157.71
35.05
621.13
1,095.82
654.93
123.94
$1,095.24
$7,730.52
$1,613.20
$264.73
Receipts $30,740.00
Expenditures 17,210.66
Balance 13,529.34
JOSEPH M. TO 1H. )4.D.
EcTON
'IdI2 iiiMtn Xerag
13UREAU OFRESARCH IN NEUROLOGY AND PSYCHIATRY
C/0 NEW JERSEY NEURO.PSYCHIATRIC INSTITUTE
BOX 1000.
PRINCETON. NEW JERSEY
March 2, 1962
�
1;tzachod s;ou will find iniefim report of our expendi-
tures thilifek grant from the tieriod beginning
June 1, 1561 and encling May 31, 1962.
bgs to rdnd your-proslised trip to see our labora-
tory at-f: the pro,..iress in our research efforts. We hope that
the ::�c-rh of March will afford you time for such a visit since
we now Ila-sie much to show you.
best regards,
CCP:mc
Att.-(1).
Yours sincerely,
e
./
Carl C. Pfeif.L/ er, 11.1)
Head, Section en Mari ology
^
Period Ending March 1, 1962
Personnel Salaries Permanent Consumable
and Wages _ Travel me i n Equpt
. .._ � Supplies ether
-
.
$1,148.40
1,070.80
665.4Q
3,492.00
130.37
$6,506.97
,
$ .1.:47
$1182.44
$ 447.30
$ 45.35
65.09
3,418.78
205.55
4.00
102.94
1,259.65
147.71
56.39
304.61
773.83
157.71
35.05
621.13
1,095.82
654.93
'
123.94
$1,095.24
$7,730.52
$1,613.20
-
$264.73
Receipts $30,740.00
Expenditures 17,210.66
Balance 13,529.34
�
-
NEW JERSEY MENTAL hEALTH
RESEARCI-1 AND DEVELOPMENT FUND, INC.
Truqe,es
JOSEPH M. TOBIN. M.D.. Chairman � PAUL MUM M.D. Vice Chairman � HENRY P. DAVID, PH.D., Sactetary Trcarprer
V. TERRPLL DAVIS. M.D. � MAURICE. G. ROIT. PH.D. � DOUGLAS H. MAr_NEIL � LLOYD W. 2.1c-CORKLg. P.D.
. October 24, 1961
Addra'ss Corte 2pondence Io
Henry P. David. Ph. D.
Secretary Tressurer
I Jill Lone
Trenton 8. N.J.
De Dr.
�
It 13 with pleasure that_racknowledso your recent
contribution of D.5,370.00 as the first payment
on the-new grant7under�Dr�Cerl Pfeiffer.
Yours sincerely,_
Henry:P. David, Ph.D.
Secretary--Treasurer
HPD:cf
cc: Dr. Carl Pfeiffer
Mt.
Contributions ate 111-dvcr,bte lot FC"farat Income Tag rurpo,eL
CEiP
Receipt Is hereby acknowledged of the following two checks;
Treasurer's Ch6-ek No. 184354, dated July 26, 1961, drawn on the
in the amount of $1,229.60, payable to the
Treasurers Cheek No. 267969 dated July 26,1961, drawn on the
- in the -amount of $30,740.00, payable to the
-
1 Y7':!:
6:04A-4.
.JNA4t to Carl C. Pfeiffer, Ph.D., M.D
June 1, 1960 to May 31, 1961
with Nev Jersey Mental Health Research and Development Rind as the Recipient
Receipts
September
1960
January
194 -
,
May
1961
Total receipts
EXpenditurcs
'Laboratory equipment and _supplies__,_
Office equipment and supplies
$38,632.64
_ 6,o18.57
Salaries and wages - --_
2,888.86
Travel
1,555.38
Socks
402.55
Total expen itures
:49,498.00
��11.
cc. Joseph M. Tobin, Director, 7->ireau of Research -
David Henry, See. Tres-s.-,_rewJersey_r;enW,Health Research and Development Fund
�I:"
%ten
3
�
e"..7
e>1
NEW JERSEY MENTAL HEALTH
RESEARCH AND DEVELOPMENT FUND, INC.
Trustees
JOSEPH M. TOBIN. M.D. Chairman � PAUL MUM M D. Vic* Chairman � HENRY P. DAVID. PILE), Sacritary Treasuraa
V. TERRELL DAVIS, M. D. � MAURICE G. XOTT. Fn.D. � DOUGLAS H. MAcNEIL � LLOYD W. McCORKLE� PH.D.
AdJrass6orrespon4ancat to:
I fenry P. David,. Ph. D.
Secretary Treasurer
I Jilt Lane � -
Trenton 8, N. j.
Nay 12, 1961
It is __a _pleasure to acknowledge receipt .
of your check In the amount of twelve thousand
three hundred sevonty_four_dollars_and fifty cents
($12,314,50), representing the'fourth quarterly
payment -supporting the research program of Dr. Carl .
C� Pfeiffer.
Yours sincerely,
Henry P. David, Ph.D.
Secretary-Treasurer
HPD/1m
CC: Dr. Carl C. Pfeiffer
Dr. Joseph Tobin:.
COM f ;b4.11;011.11 AFC lar Fe-dcrol I,.-.e Tai P.,rpaNes.
� -*
`'�t;-1!;-.
=
.� "-,�,Z.z.:�;�.- � c."�,,
c�� � :����.'Z "."
^ . �.�
. . �
-. � . .- 12 lel
�-� �. . .
1.134:MOIL4�14131JI.11"Cit: -Cilief, Finance Dion
� � ,.. .5. � ,
' � ... � ....,_
. , � . � _ .. . s '� : � ��� .7,7-----"` � � � � �,
� � � ... � ' ." ..' � .� � ���� :".: � � - z. '''' � ��.�
...
VIA .-- � �- --,�-� - � � - - t-TSDIZzlagot �Meer . ���:'�*. - . - - �-.. -..' - z. t -- � :-
- - � . - .- . - - - -.-- -.� -.....A '5 . ���:-. 55 '
� �
, � � � . � � �4 .' " " . - " ` �' . �..5. �'. � �� '1'
- - - ' � .� . - s �. - ...
- . � �
SUBJECT ' . I ?..MULTR.A,Subproject 47, itrIVAC 5 No, 32 �.1- ..: - .--. � '.�
.. .
� �� �Alletrnent4.125-1-390--3902.
. . � ". � ; �
� � � . � � - �
��' � -� �
�
.. � .
1. Inioice No 12correring the above subproject la attache/L. .
Payrarn't -obi:A.11d be mule as follows: t . . : � :"�
^ Cashtr'3 check in the Amt Of $35,740. 00 drawn on ts. � �.�
- � -
� . � .�
�
-
� � � 7 "7:���� : �
�-.7....Cathiarla check in the avio-ant of $1,229.60 di aWil 0.12
� -(e)le',��Th-L�'�-re.X-tri,M,, bank. *.�
- � � � � � �
�
ahoull bo vlyabla to ths
_
. � .
� - ��� . �
� ������ : 24. rirleaso forwla;.4 the cheelto to Cief, TSD/Reeeriach Drantb,
thrcrash_ %.--SD/Butizet Cificar by Z4 Itlly 1961. � . a� �� ���
. � � " L: .7." 7 �
' � . : � � � - �
� --�� � 3, 121)11s-a. Invelce. However, etato it le.e,ntlIpated .."7;
�.-- -
thitttri furae veal be obligntN1 for thie project, t'.`le files -
� oho:44:1ot be closed.
. �
i�
����
� . � � � �
- � �
Attached: � '�
� invoice Ic Certificztion3
- TSD/R
B:
� � � .
- � *�:.e.-.� �
� �...-f,�����
� �
. �
Diotril>utien: . ��
Ortg, Z 11,1-4ro,Doct
-1 - irpf.Fitss--
TSD/11.11
(A)
�
���
� . � ���
CAVIrat�50
� � . k �
Chief ' �
��7-51.0/Re-nearettr:ra-nch. �
� : .� � �
� � .
-For Services
CEWIFICATIONS_
(1) At ia hereby certified that this is Invoice la -applying to_sult-project
Ho. 44 of NEULTRAi, that perforance is satisfactory, that services are being,
acc'84I1she1 in accordance with mutual-agreementa,:that a detailed aunda of :
the payments and receipts la on file in SSO/RBi that this bill-le-just and
correct and thot parent thereof haa not,yetbeen_made.
$31, 969. 60
Date:
%
1,
�
TSD/hesearch Branch
47 III
(2) It is hereby certified that this invoice applies to SubProject_ _
of MXULTRA vhich vas duly approved, and that the project is being carried out -
in accordancevith the mecioranduat of APrill953 fiom the DCI to the DD/A,
and the extension of this authority in subsevent-aoranda. - _
Date:
Research Director
(When Filled In
No.
Cost Account _at/ail:-
Object Class
Date
-
20 liusli
Remarks and References
Obligations
Incurred
Obligations
Liquidated
Unliquidated
Balance
J Oil'
�0 1:1141..
�
24;ra
.47-(47�14-
l
1%
714 '.-19
---
b RUL-rRII-ScJ)-1311.6./L--.o.trii,t-}
4,
24;97I
J.- 7,- rj
024 0 CO .0
---
_______
-
4.
.
-
.
_
.
- --.
(
une 1981
MEMORANDUM FOR: COMPTROLLER
Finance Division
MKULTRA, Subproject 47 Additional
Authorlication No. 9
Under the authority granted in the memorandum dated 13 April
1953 from the DCI to the DD/A, and the extension of this authority
in subsequent memoranda, Subproject 47 has been approved and
$31,969.60 of the over-all MKULTRA project funds has been-
obligated to cover the subproject expenses. This obligation of
_
funds should be charged to AllotMent 2125-1390-3902.
APPROVED FOR 0131.1CA TION
OF FUNDS:
Research Director
1z .h'
Distribution:
Orig & 2 - Addressee
1 - 'LSD/ OC
c1----TSD/FASS
2 - TSD/RB
Chief,
TSD/Research Branch
I ((tTrrY ViA1 flP*S AR! AVAP-11,8t.
opoc�Itz.1 ittittr:CI 143.
pikt01 10 1.11:a!71),1 e412
AtalloR.Z(NG Qirtcte
PROPOSAL
�
�17
SUBJECT: The Testing in Animals and Human Volunteers of Chern,fcals
and Biochemicals Which Alter ,Behavior.
PLACE:
The New Jersey Neuro-Psychiatric Institute
The Bureao,of Research in Neurology and Psychiatry
Princeton, rew Jersey (P.O. Box 1, 000)
PRINCIPAL INVESTIGATOR: Carl C. Pfeiffer, Ph.D., M.D.
GRANT ADMINISTRATORS: New Jersey Mental Health Research and
Development Fund, Inc.
1 Jill Lane, Trenton 8, New Jersey
Henry P. David, Ph. D., Secretary-Treasurer
It Is proposed to conduct screening and range finding tests on volunteer
with chemical compounds of known behavioral activity. Studies will be
conducted on derivatives of selected biologically active compounds to deter
mine their action on the central nervous system of if-an.
In addition to these investigations, the following work will be undertaken:
� 1. Pharmacological testing will be conducted on animals
utilizing candidate hallucinogenic chth-nicals.
2. Studies will be conducted on compounds of relativly
simple configuration to assess their ability to inhibit trained
behavior in animals utilizing the condition avoidance responses.
3. Studies will be conducted of compounds in normal human
volunteers for possible behavioral changes utilizing compounds
provided by the sponsor.
4. Quantitative studies of the EEG in animals and man to
determine stimulant or depressant effects of candidate mater-
ials.
(Whet. PnJad in)
CONF I DENT I AL FUNDS POST I NG VOUCHER .
0 Ot NO 7.12
DATE 7.4 iVOLICNER NO. 7.17
1
0 CRIPT1ON.ALL OTHER ACCOUNTS 13.33 1
34."
STAT,ON
80.42
4,'
AS.A
47."
08L16.
53 s4.47
58.47
ALLOT. OR 'COST !
48.70 71.80
OVE IANGoNT
CODE
EXPEND
V
FAY
REF. NO.
GENERAL
ACCT. NO. . .
DATE
OESCRIPTION.
ADVANCE A=01.0175.12.27
..........
....No.
j...
"""
1'400., 010.
COOE
N
"ft*
i.10..
' ' ; '''
A�:"""
CA
1 R
LEDGER f 42.87
ACCT. NO. 4a.me,
I.........
......
441JtC4
0444T
C COI,
.
*�* '''' *****.
, a./ w,
.._. .
ONO J.CCY ;O.
V
D
s
Coot
.;;;:.......
1 4 41o.44.
,.. ..
'""
...
�
�,��
c6 elD
V����=INII����11,�����.�����=�����
j
�
1 7
Aol
1
e
. p
elVo
1
' N.:�
. r...'
,
r
if
,.
''.1.1A2.)9
e�����������
1
...'...
f
.
.....
'
'
' �2PLANAT1ON OF ENTRY
TOTALS �
I
�
e
.�
DATE
PNEPANCn NY
DATE CV1ERED OT 1 C DY Fla) FOR P y RI OP C 09T
'1C 1#1
74) 41A/

TE IGNATORE OF 'CEMT1FYING OFFICER
FORM
10.509 WO WIC 04144101.14 44111444.
. 4.4 �
��� �
..� t� t
;1 ��,�wi m���� � ������ � ���.. � � 041.. *
to� � :4 ��� �� �
_
12 July1961
EMOItANDUM FOR: Chief; Finance DMsion
VIA t TSD/Budget Officer
SUBJECT- t MICULTRA, Subproject 47, twoice No. 12
Allotment 2125-1390-390Z
Invoice flo 1Z covering the abeve saproject
Payrriend should be made As follows: -
attache-a.
Cashier's check In the amount of $30.740.00 drawn ea a,
bank.
Cashier's checkin the amount of Si, Z29.60 drawn oa
bank.
Cheeks phonid bo tnade payable to the
Z. Pleate forv..ard the checks to Chief, ;TSD/Research Branch
through 1'5D/11w:1g-et Officer by 24 Jvly 1961,
3. This is a final inVioice. lio�Vever, otnco it is anticipated
that edditioaal &ads will be obligated for ,this project, the flies
should riot be closed.
AV;r0.
Chief
TSD/ftcsearch Branch
Attached:
Invoice 14 Certifications
Distribution:
Orig & 2 SACO
�
(Who.. filled In)
;Z '-- 2-15'
.!1��-.1
I CONFIDENTIAL FUNDS POSTING VOUCHER
IvoucHER NO. 7.12 I 0.0E 7.411
I 7,VOUCHEW NO. 7*I2
I
DESCRIPTIOWALL OTHER ACCOUNTS 13. 5 74.30
sy,010N 1.60*42
43.
45.4,
A7.67 '
OBLIG.
SS
* 50.47 .70 71.40
ALLOT. oR cosy 04c
20.33 CODE
7/A NO.
cspcNo
F
4
PAY
REF. NO.
sR.sy
GENERAL
ACCT. NO. DATE
AMOUNT
DESCRIPTION*
ADVANCE ACCOUNTS 1S:27
. '�"
p.o. mo. POOP. NO.
CODE
N
,.
'
LID.
tCPUM70.
CA
YR
LEDGER
62.67
CR. me. 0 0/1[CT
. ,,,,..
CAC 0 I If
.......,JA.
111PROJCCY
****". -.7-771,1;
NOI
' "%;07
ACCT. NC.
�*"":" c�alis
A RCP. 0.0,i
: ---
47.11.10.?
L
#
e e.
e,-r'rsv
1
M,
1
1
�I),/ I) :5-134o4-7,-)'-.1)�
7.:::-%,x
�
6
';-:7
"se
'
: �
1,j
�
!*.7.7.
� -.7-
� �
..
Z://.
y
.
.
w
./;.
� .--
1
.t.;..fi
a
.
.
I
...
..
I
�
.
�
���� ,
.
...
L
.
EXPLANATION Of ENTRY
DATE PCPAlCD
7
FOR.
10-5, WG11, URIC FA f1002 (01110
Fr
DATE
EVIEWE0 DY
4af:=St�
TOTALS
CE IFIE0 FOR RAYmEmT OR CREOT
DATE IsioNATuRE Of CERTIFYING OFFICER
(704,40)
411-:
'
26 April 1961
MEMORANDUM FOR: Chief Finance Division
VIA
SUBJECT
TSD/I3udget Officer
MKULTRA, Subproje-ct 60, Invoice No. 7
� Allotment 2125-1390-3902
1. Invoice No. 7 in the amount of $18,500 is attache& However,
due to refunds of $5,582.12 from this and one other project (as per
attachments) payment should be made as follows:
Cashier's Check in the amount of $12,917.88, drawn on st
local bank, payable to the Soitity-to-I the Investigation �Of
-Human E_cology,� �
2. The checks should be forwarded to Chief, TSD/Research
Branch, through TSD/13udget Officer, no later than Monday, 8=Iviar1961.
3. This is _a final invoice. However, since it is anticipated
that additional funds will be obligated for this-p-roject the files should
not be closed.
Attachment:
Invoice bt Certifications
Distribution:
Orfg b.. 2 - Addressee
Chief
TSD/Research Branch
73!36
PROPOSAL
SUBJECT: The Testing in Animals and Human Volt:nteers of Chetacals
and Biochemicals Which Alter Behavior..
PLACE: The New Jersey Neuro-Psychiatrie Institute
� _
The Bureat! of Research in Neur-ology and Psychiatry
Princeton, New Jersey (P.0. Box 1, 00D)
PRINCIPAL INVESTIGATOR: Carl C. Pfeiffer, Ph.D., M.D.
GRANT ADMINISTRATORS: New Jersey Mental lieialth Research and
Development Fund, Inc.
1�Jill Lane, Trenton 8, New Jersey
Henry P. David, Ph.D., Secretary-Treasurer
It is proPosed to conduct screening and range finding tests on volunteers
with chemical compounds of knov.-ii behavioral activity. Studies will be - -
conducted on derivatives of selected biologically active compounds to deter-
mine their action on the central nervous system of man.
In addition to these investigations, the following work will be undertaken:
1. Pharmacological testing will be conducted on animals
utilizing candidate hallucinogenic
� 2---Stuclies will be conducted on compounds of relativly
simpl&snfiguration to assess their ability to inhibit trained
behavior in animals utilizing the condition avoidance response
3. Studies will be conducted of compounds in normal human
volunteers for possible behavioral changes utilizing compounds
provided by the sponsor.
Quantitative studies of the EEG in animals and man to
determine stimulant or depressant effects of candidate mater-
ials.
MEMORANDUM FOR: THE RECORD
SUBJECT
MKULTRA Subproject 47
DRAFT
1 June 1961
1. 'The purpose of this subproject 47 is to provide funds to continue
a research program being carried out by Carl C. Pfeiffer, MD.
. The nature of the investigationS to be carried out under the
direction of Dr. Pfeiffer encompasses pharmacological and clinical
testing in animals and human volunteers of chemicals and biochemicals
which alter behavior. Certain phases of other problems of interest to
TSD will be investigated.
3. Dr. Pfeiffer is located at the New Jersey Neuro-Psychiatric
Institute in the Bureau of Research in Neurology and Psychiatry, Princeton,
New Jersey.
4. The funds for this project will he transferred using the
as a cut-out
5. The cost of this program for a period of one year beginning 1 June
1961 will not exceed $30, 740.00. To this sum must be added $1,.229.60
representing a 4% service charge to the
making the total amount $31, 969.60. Charges should
be made against Allotment iZ125-1390-3902.
6. The New Jersey Mental Health Research and Development Fund
Inc., who administer the grant have agreed to provide th
4�Owit a summary accounting on an annual basis of all monies received
5
13,
41TIMirtr
from th
funds to the
year.
� t
sc+f� ate
�+1-41t1-11.r
�
- � 'IPA .
12 r _i� CL BY 1Q7475
They have also agreed to return any udexpendevil
as soon as possible upon the close of the grant
. The requirement for a six months' informal accounting on the part
of the principal investigator is waived.
. .fritle to any permancnt equipment purchased by funds granted the
..
New Jersey Neuro-Psychiatric Institute shall be retained by the Institute
in lieu of high overhead rates.)
9. In connection with travel under this project, it is agreed that the
Agency will accept the travel documentation and accounting which conform
with the practices of the New Jersey Mental Health Research and Development
Fund Inc.
10. It is agreed that technical reports reflecting the progress of the
research program shall be submitted at mutually acceptable intervals.
11. Dr. Pfeiffer has signed the Memorandum of Agreement and holds
a TOP SECRET Agency Security Approval.
APPROVED FOR
OBLIGATION OF FUNDS:
Date:
Research Olrector
�: I
Attachments:
Proposal & Budget
Distribution:
Original Only
Chief,
'f'SD/Research Branch
'17
PROPOSAL
SUBJECT: The Testing in Animals and Human Volunteers of Chemicals
and Biochemicals Which Alter Behavior.
PLACE:
The New Jersey Neuro-Psyehiatric Institute
The Bureau of Research in Neurology and Psychiatry
Princeton, New Jersey (P.O. Box 1.000)
PRINCIPAL INVESTIGATOR: Carl C. Pfeiffer, Ph.D.� M.D.
GRANT ADMINISTRATORS:
_
New Jers-ey Mental Health Research and
Development Fund, Inc.
1 Jill Lane, Trenton 8, New Jersey _ _
Henry P. David, Ph.D., Secretary-Treasurer
It is proposed to conduct screening and range finding tests on volunteers
with chemical compounds of known behavioral activity. Studies will be
conducted on derivatives of selected biologically active compounds to deter-
mine their action on the central nervous system of man.
In addition to these investigations, the following work will be undertaken:
1. Pharmacological testing will be conducted on animals
utilizing candidate hallucinogenic chemicals.
2. Studies will be conducted on compounds of relativly
simple configuration to assess their ability to inhibit trained
behavior in animals utilizing the condition avoidance response
3. Studies will be conducted of compounds in normal human
volunteers for possible behavioral changes utilizing compounds
provided by the sponsor.
4. Quantitative studies. of the EEG in animals and man to
determine stimulant or depressant effects of candidate mater-
ials.
SENS/II
ACES
NCE
INVOLVED
Research"Froject ApplIcatAo Pieiffer
Requested Budget
June 11_1961 thru May 311_1962
TITIE
Principal Investigator Carl C. Pfeiffer, Ph.D., M.D.
Senior Research Scientist,
Paid by State of New Jersey,
Clinical Pharmacologist
Neuropharmacologist,
Technician & Animal Man,
SecreteryA04W
Stipends - Human Volunteers
Equipment
M.S.
Consumable Supplies: Animals, Animal Food,- Biochemicals Paper._._
fof ESO
Travel to Scientific Meetings & Conferences_
AMOUNT
25% $ 000so
25% None
75% 10,000.00
540% 6,0o0.o0 -
l00% 7o60.00
35% 1,280.00
1,500.00 4
None
3, 1o0.00
00.00
TOTAL $30,70.00
In lieu of overhead, the New Jersey .Mental Health Research & Development Fund will
retain title to any equipment which may be purchased -under said grant.
RNIN ()TICE:
_LLIGr` C
OD iN VOt
6
RECEIPT
Receipt Is hereby acknowledged of the following two checks:
official Chick No-...G4Z7-8i; dated July 7, 1960 , drawn on
in the amount of
$49,498. 00, -payable to the
".12.7Mt.
- Official Chick No. "642786, dated Jul
� ___
$1, 979. 92, payable to the
.4grrero;:A,
'Mk
-
-B
1,-l960, drawn on
, in the amount of
29 June 1960
.I" �
MEMORANDUM FOR: CHIEF, FINANCE DIVISION .
-
VIA
i TSDIBu-dget Officer
SUBJECT MKULTRA. Subproject 47. Invoice Ill
Allotment 0525-1009-4902
���
I. Invoice Ill covering the above subproject is, attached.
Payment should be made as follows:
6
Cashier's checkin the amount of $49493. O0 drawQ
on
aikill&MS61,04.
Cashier's 'check In the amount of $1,979.92, drawn
on
Each check should be made payable tcth
4Witif -::�iictir4, .
. 2. Pleace forward the checks to Chief, TSD/Research B
through TSD/Budget Officer by 13 July 1960. ,
anch
3. This Is a final invoices However, since it Is anticipated
that additional funds will be obligated for this project, � the files
should not be closed.
Attachment;
Invoice le Certifications
Distribution: .
Orig & 2 - Addressee
I - TSD/FASS
/2 - 'fSD/GB
TSD/Res eareh Branch
�
For Services
INVOICE
a
I
CERTIFICATIONS
(1) It Is hereby certified that this Is Invoice ill applying to Subproject
47 of MKULTRA. that performance is satisfactory, that services are
being accomplished In accordance with mutual agreements, that A
detailed agenda of the payments and receipts Is on file in TSD/RB- -
that this bill is just and correct and that payment thereof has not
yet been made. - -
� Date:
Chief, TSD/Research Branch
(Z) It is hereby certified that this Invoice applies to Subproject
No. 47 of MKULTRA which was 'duly approved, and that the project--
1e being carried out In accordance with the memorandum of 13 April 1953
from the DCI to the DD/A, and the extension of this authority in subsequent
memoranda.
Research Director
.-t4icerEffs*"
1.14
V..
zv tor ty or" :3 475
377
C BY 1 75
DRAFT
20 May 1960
1.:EIV.013,ANDLYM FOR: THE RECORD
SUBJECT : MKULTRA, Subproject 47
�
I. The purposel:of this subproject is to provide funds to continue
a research prograrn being carried oat by Carl C. Pfeiffer, M. D.
24 The nature of the investigations to be carried out under
the direction of Dr. Pfeiff,:.r encompa 3es pharmacological and
clinical test inz in animals and human volunteers of chemicals and
biochemicals which alter behavior as outlined in th attached roposal.
3. Dr. Pfeffer was Previously-located at the Emory University,
Atlanta, Georgia. He is now located at the New Jersey Neuro-Psychiatric�
Institute in the Bureau of Research in Neurology and Psychiatry, Princet;n,
New Jersey. This change in position will not in any way interfere with the
Lgency sponsored work, in fact, Dr. Pfeffer will have access to more
and better equipment and personnel for his reteareh.
4. The funds for this project vill be transferred using the
,0404.441"PM-
�
4S a cut-out.
5. The cost of this program for a period of one year beginning
1 June 1960 will not exceed $49,498.00. To this surn must be achied
$1,979.92 representirg 4% service charge to the
91 I
8747
87475
laking the total amount $51,477.92. Charges
should be made against Allotment 0525-1009-490Z.
- I). The
s requested The ew Jersey
Mental Health Research and Development Fund, Inc., who administer
the grant, to submit to tbern a summary accounting on an acnnal basis
of all monies received from the FtTod. Also, it has been reqiested that
any cnexpended funds be returned as soon as possible upon the close of
the tart year.
7. The requirement for a six months' informal accounting
on the part of the principal investigator is waived.
8_ Title to any permanent equipment purchased by funds
greeted the University shall be retain&I by the University in lieu
of high overhead rates.
9. In connection with travel under this project, it is agreed
that the Agency will accept the travel documentation and accounting
which conform with the practices of the University.
10. It is agreed that technical reports reflecting the pr0gr(08
of the research program shall be submitted at mutually acceptable
intervals.
0
-3-
tf
U3I4i3
11. Dr. We. iffer has signed the Memorandum, of Agreement
and holds a TOP SECRET Agency Security Approval.
APPROVED FOR OBLIGATION
OF FUNDS:
Research Dir&kctor
Date:
611c1(00
At
Propoeal & Budget
Distribution:
Original only.
-:74?'"4453-744'6---�
sy.,74
Chief
TSD/Chernical Branch
13
RESEARCH PROJECT-APPLICATION �
�
_PROPOSAL: The testing in animals and human volunteers o chemicals and Mee
. _�
chemicals which aPter behavior.
INTRODUCTION: The
investigator for more thin ten years, during which time many notable advances have
been accomplished. l
iiaAt present the - supports the search for new allucinoeens (chemically
simpler than LSD-2_9). These are synthesized by tested in animals and in
vitro systems and then cautiously tested in man. �1/4.ezeizia=* iS taking a leave Of
absence next .year and will work in 1951 as head of medicinal chemistry in the
. His synthetic work will continue in
1951, and in 19e.0-.1961 we wilt test the backlog of compounds already synthesized.
The grant to Emory will terminate as of May 31, 1956, which is the close of the
present grant year. Other funds are available at Emory to cantinue the testing
of the ompOunds at the Atlanta federal Penitentiary under the direction of
11 0. from the period June I, to December 31, 1960. By
this time the human testing will be organized and progressing in New Jersey under
the direction of the principal investigator. On July 1, 19514Q4=1.9==bt will .2 -
have completed his last six months of a split internship and will join the research
team in the Nelot Jersey location.
�
PLACE: The New Jersey Neuro-Psychiatrie Institute
The Bureau of Research in Neurology and Psychiatry
Princeton; New Jersey� (P. O. Box 1,000)
PRINCIPAL INVESTIGATOR: Carl C. Pfeiffer, Ph.D., M.O.
GRANT ADMINISTRATORS: New Jersey Mental Health Research and Development Fund, Inc.
1 Jill Lane, Trenton 8, New Jersey
Henry P. David, Ph.D., Secretary-Treasurer
IN
has aided the research studies of the principal
RESEARCH PROPOSALS:,
A. Pharmacological testing in aninals of candidate hallucinogenic chemicals.
B. Study-of simple compounds which may inhibit trained behavior such as the
conditioned avoidance response.
C. Careful study of compounds in normal human-volunteers fOr possible behavioral
- -changes: C...--,
1) � '` synthesized compounds
2) Compounds supplied by 4W113; t 4 far. ;WI t743Ii 13
3) Bioche_micale purchased
-WAR. 11 F. TICE
_ sEriSi IrE I ii ;ENCE
4.21K-Est. nib: IN OLVED
(7)
Research Project Application - Pfeiffer
D. Quantitative studies of the EEG in animals and man to determine stimulant
or depressant effects;
E. Annual conference on the neuro-biology of psychoses.
f5
Proposals A, 8, and C are a continuation of th ork now in progress which
is familiar to the officers of TheSiVSaVai% . from our annual and s'emi-
annual reports. Under C thrt:,.source of human volunteers will be the 100 reformatory
inmates (ages 18 to 28) who .?re stationed on the grounds of the Institute. If 16
volunteers, aged 21 to 28; asre not obtained frail this group for a weekly session
of drug testing, we will have one session of eight subjects at the institute and
one session at the New jersey-State Prison in Trenton. %Commissioner erainberg has
given his permission.
Under D we now have perfected and plan to use at the New Jersey Laboratory a
quantitative integrator for drug studies in both man and animals.
Adult unanestheti2ed, trained animals are used. Under anesthesia small gold-
plated wood screws are used as dural electrodes. These are lightly engaged in the
calvarium and held firmly in place with methacrylate with the permanent lead
attached. The recording leads are bipolar from the left and right frontoparietal
lobes of the brain. The animals are in a sound attenuating box and sit quietly for
the entire 1 to 2 hour session after a few training periods.---
A Orohocki integrator is attached to one lead. This device rectifies the brain
waves and by a chopping process, counts the area under the rectified curve. A
signal is made at a pre-set degree of sensitivity. The number of signals per unit
time is a measure of the degree of-electrical activity or "electroeenesis." The
number of pulses or signals is directly correlatable with the area under the curve.
The constancy of the electrogenesis with elapsed time can be calculated and treated
by the usual statistical methods. In this type of analysis, periods as long as
five minutes can be used as a baseline or control ad thus transient artefacts are
eliminated. The action of drugs is usually measured at 1-5 minute intervals after
intravenous injection and the drug action is expressed as change in percentage
electrogenesis from the control preinjection period. AroLsal or stimulant drug
effects are recorded as a decrease while sleep (sine waves) produce an increase in
electrogenesis.
E. Annual conference on neurobiology of psychoses. Most previous conferences
of this type have been poorly planned, and the group has been too large and unwieldy.
honey spent on verbatim recording and publishing is wasted, and this process further
inhibits the participants.
The participants will be limited to 12 or l5. The record will be in the form
of the individual's own notes and the notes of a scientifically trained secretary.
The summarizing secretary will change with each three-hour session. In a two-day
conference we would have five sessions of three hours each.
The coaference would be held in just before or after-the V:I=gd;g0.
Only
scientists with a biological approach to mental disease would Le invited. The
various basic disciplines would be represented. Some of the participants might be (2,'
_
VklAr*11NG
SENS TIVE
SOURCE'S S INVO
TT:k:
Research Project Application - Pfeiffer
Page 3
Prior to the meeting a questionnaire on possible biological factors in i.ental
disease would be circulated to the participants, and their response to these possible
etiological factors listed would determine the agenda and the priority of the factors
discussed.
Possible biological factors which will be included in the questionnaire are for:
� The Schizophrenias (assuming a heterogeneous clinical entity)
1) Defective keto-acid utilization
2) Defective carbohydiate utilization
3) Decreased level ofblood glutathione
4) Therapeutic effect of intravenous glutathione
5) Increased ascorbic acid requirement
6) Increased ceruloplasmin in acute schizophrenia
7) Therapeutic effect of ceruloplasmin
8) The effect and role of Taraxein
9) Increased adrenal cortical and medullary activity
10) Increased urinary catechol amine excretion -
11) Increased urinary indole excretion
12) Epinephrine metabolism
13) Serotonin
14) Thyroid function
15) Estrogen-androgen function (more co-lmon in female?)
16) Liver function tests
17) Co-enzyme :activity (hippuric acid synthesis) Co-enzyme A
18) Effect of growth hormone
a) Occurs when somatic growth stops
b) Postpartum psychosis
c) ACTH psychoses
19) Childhood autism and the adult schizophrenics
20) Pineal gland extracts
21) The schizophrenias in the blind
22) Sensory deprivations and psychosis
23) EEG abnormalities
a) Heath's septa] spikes
b) 14 and 6 disorder
c) Goldman's fast activity after pentothal
24) Biology of electroconvulsive therapy (change in cholesterol esters)
25) Biology of insulin coma therapy
26) Specific effects of nicotinic acid therapy
27) Specific effects of phenothiazines
28) Specific effects of reserpine
29) Specific effects of deanol
30) Porphyrin metabolism
31) Thioctie acid
32) funkenstein tests
33) Response to histamine and allergies
34) Overdosage of amine oxid3se inhibitors
35) Influence of tuberculosis, influenza, etc.
36) Somatotypes
Rescarch Project Application - Pfei(Yer
Depressive psychoses
I) Amine oxide inhibition
2) Action of electroconvulsive,therapy or insulin
3) Deanol therapy
4) Blood bu(ane-2, 3-diol levels
- 5) Somatotypes
. Manic psychoses
1) Effect of lithium
2) Metabolism of uric 'acid
3) Hyperthyroid mania ''
4) Neuraminic acid
5) Catechol amine excretion
6) Indole excretion
7) Bloocracetoin levels
8) Effect �of phenothiazines
9) Somatotypes
SEN
SOURCES
41
Research Project Appli
zgUIVAtiVics..
bon - Pfeiffer
BUDGET
C
ki7..3(1
page 5
Time
Principal investigator, Carl C. Pfeiffer, Ph.0.,./.1.0.
25%
4,000.00
Research Psychopharmacologist, '
100%
7,500.00
Clinical Investigator (M.D.):
100%
12,000.00
Stipends Human volunteers!
4,000.00
Technician
100%
4,500.00
Secretary
50%
2,W0.00
Animal Man
50%
1,500.00
1
0.A.S.I.
648.00
Equipment
2 Electrified conditioning cages for animals 43 $250.00
500.00
1 Constant intravenous infusion pump
350.00
1 Polygraph Grass 4 channel with stimulator and transducers
4,800.00
Consumable Supplies
Animals, animal food, biochemicals, paper for EEG
4,000.00
Travel - To scientific meetings and locally to.Trenton 'State.
'Prison and4iospit#17
1,500.00
Miscellaneous - Photographs and reprints
200.00
Conference on neurobiology of psychosis
2,000.00
$49,453.00
In lieu of overhcad the Hew Jersey Mental Health Research and Development Fund will
retain title to all permanent equipment purchased under said grant...
The above grant is requested for the period June 1,..1550 through May 310 1961.
OTICE
10DS
C
47,
Chief
. TSD/Chernical Branch
ss�
20 May 1960
MEMORANDUM FOR: COMPTROLLER
ATTENTION : Finance MAIiota
MKULTRA, Subproject 47. Additional
�.Authorisation No. 8
,
Under the authority granted in the memorandum dated
13 April 1953 from the DC1 to the DNA, and the extension of this
authority In subsequent memoranda, Subproject 47 has been
approved and $51;471.92 Of the over-all MKULTRA project funds
has been obligated to cover the subproject expenses. This
obligation of funds should .te charged to Allotment 0515-1009=4902.
� APPROVED FOR ODLIGATION
OF FUNDS:
Research Director
Distribution:
Orig & Z - Addressee
1 - TSD/OC
1 - TSD/FASS
2 - TSD/CB
TSD/CBtit�
t
V?.
F:A3RY
De-N__11r_tnerit, of Phan-zcolo-v
�
Dr. Carl C. Pfeiffer, Director
UrV oz' Receipts �-��1�3 r--erdi4ures for the Period.
1 52Ltoul V:s.�.. 31, 1.950
iReceivecl fron�fttl. - 1959-60
*DLR1-'4.12 DCP1-11,IDrAKIES:
� Personnel 23,359.39
Fellowships 7,303.00 :
Fu..--..sn Subjects _ 3,310.00
�
Travel - 2,919.36
EourGment � ),O35.68
"01 e SuRcli'es _2_1711122
Total Direct F\-:penaitures ..'`j7+3,668.42
iniirect Costs 4,355.84
TOTAL DTZ:401.11.1:-tES 08,C35.26 �
-*See attaened schedules
Approved;
;
C2r1 C. neiffer,
�Froject DIrecfor
I h7,-.-a :7!1 the
Div!slon
6,377 .50
rmnl(vee
Annuity--
44.
Subjects
1-14DRY 11141VERSITY
Danartt,ent of PharnacolOm
Dr. Carl C. Pfeiffer, Director
PgiSO/Ziki
Position
Li 7
Iknonnt
Research Assistant $ 2242.00
Research Assistant 3630.00
Instructor 300.00
Assistant Professor 300.00
Assistant Professor 8916.58
Associate Professor 900.00
Research Asgist.cmt 1040.00
Research Technician 2240.44
Assistant 13.95
Resecrch Technician 1075.00
Technician 99.96
Research Technician 1050.00
Anjicar ittendant 390.00
Assistant 669.00
14.68
SoCial Security 411.58
$ 23359.39�
FFILOWSITIFS
Fellow $ 600.00
Fellow 600.00
Fellow 300.00
Fellow 300.00
Fellow '500.00
Fellow J000.00�
7300.00
$ 3310.0o
3
EI,DRY tIIIIVERSITY
aate
8- 7-59
/
8-
9-59
8-3C-59
/
9-
3-59
8-3c-59
/
9-.3-59
8-29-59
/
9-
3-59
8-20-59-/
9-
4-59:
8-29-59
/
9-
3-9
10-15-59 /10-17-59
I-13-60 / 1-14-60
2-16-60 / 2-17-60 Carl C. Pfeiffer
2-2S-60 / 3- 5-60
Individual
Department of Ppa.:-.L-Acoloa
Dr. Carl C. Pfeiffer Director
TRAM. ,
Destination
Carl C Pfeiff.er Newark N. J.
,irr
Carl C. Pfeiffer Orlando, Fla.
3-13-6o
3-3c-60 / h- 2-60 Carl C. Pfeiffer
4-1C-60
4-10-60 / 4-15-60 attlawm
4-10-60 / 4-15-60 Carl C. Pfeiffer
Carl C. Pfeiffer
4- E-60 / 4-16-6o
4-10-60 / 4-15-60
4-10-60 / 4-20-60
.4-3c-60
4-30-60 / 5- 9-60. OtAttle:01-0
4-19-60 vASIdE
Check
Nur.ber
folotint
80000
$141.25
.1E-8-69
64.80
81429
117.75
81512
89.80
81568
173.49
SJ-9-51
156.60,
83646
130.54
88967
100.19
91317
168.45
923114
85.49
92358
60.41
94153
100.00-
94526
93.50
95031
200.00
95227
183.09
sJ-4-38
210.79
sJ-4-38
169.60
sJ-4-38
1E4.45
95888
184.15
sJ-5-19
19%70
95245
106.30
!:,2,519.36
F2DRY LIVIVRRSITY
Devartnent of Phar:lAcolm-A, -
_ -
1%
U
5.1111PVir.-iT
ITE�S
vO.No.AIDUla
&J-7k9
8-31-59
Film badze service
Refund of customs 56,030
$ 52.75
(43.09)
Farts for typevriter & film editor
85143
68.96
FreiSht
85123
4.92
Chair
- 86119 -
23.25
Dyn&xceter '
895a4 i__
91.39 .
Auto calculator
92866
1,009.40
Battery booster
92975
11.31
1,000.00
Specixophotometer
94485
Vacuum cleaner -- -
911505
36.02
Flectroencep:naloralic
Instrumentation aids
99829
Tol-al-- s.
, ?
_1;1_002,98_
ITR4
Services rendered
Reprints
Neeales
Reprints
Phe-maceutics1 supplies
Preparing infrared absorption
Book
Statistical tables
Book
Medical illustrations
Photocopy
Misc. supplies
Scxs, sav sharpened
Reprints
Vold release
Office supplies
Maltilith service
Multilith -service
Pipe
Book
Pharnz,ceutical supplies
Electrodes, potassito hydro
Reprints
Chemicals
Graph sheets
Book
Freit
M2dical illustrations
Boo::5
Filter punp,'(..Dne.erser and
M(sdical illustrations
M2dical illustrztions
Cleanin,; supplies
;se. supplies
Lon; distance telephone
Electrodes
Henole.,s
JDRYIJNIVERSIVI
Department of Pharnacoloux
Dr. Carl O._Ffeifferx_Director
SUPPLIES
vo.
76391
76733
767377
76923
sJ-6-7o
spectra 11681
78670
78689
79170
JE 781
sJ-7-50
79354
80177
8o7o9
8G/45
-
sJ-8-71
sJ-8-71_
sJ-6-104
81763.
SJ-9-26 -
e - 82487 T
82823
82353
3,304
83425
83936
84372
E24943.--
fittinrs �55575
JE-11-52
JE-12-43
87056
SJ-12-79
87,16
SJ-12-74
68111
66170
s
4.
- 3'
MOUNT
18.00
57.6,3
3.71
68.60
7.32
6.00
5.41
4.39
8.93
59;50
1.00
7.12
11.64
33.90
5.84
8.80
33.63
82.25
2.42
5.34
20.34
37.29
10.140
15. 6o
9.57
2o.39
9.94
6.00
13.91
13.92
52.53
9.00
16.00
19.57
17.51.
3.62
2.30
146.30
12.36
(continued on paGe 2)
-0
Reprints
Fhanalceutical supplies
Vise. supplies
_Reprints
CopPer tubing
V'edical illustrations
Tvo ehimPanzees
Pliarnaceutical supplies
lonG distance telephone
Kise.lsupplies
Misc. supplies
Pluss, receptacles
Flasks, chemicals
Rabbits
Ice
Photo supplies
K.!dical illustrations
Tong distance telephone
Pna=ceutical supplies
Misc. supplies
Ikuss, che,nicals
Rabbits
Reparinja
Keyort cards
Ice
Chemicals
Bar
Chromosorb
Needles
Chenicals
Graph paper
PlexiGlos
Nblication
Misc. supplies
Rabbit pellets
Rabbits
Anil food
Publication
Misc. sup-alas
AniLal feeders
lonG distance telephone
fh-_rraceutical supplies
Ice
Syrinfes
Mire blades
rase. supplies
D:y5n: jar
VO.
- (a e
MOUNT
32.09
18.20
1.85
/0.67
6.73
76.5o
300.00
53.75
1.90
83860
s4-1-82
91227
91531
sJ-2-84
SE-2-111
SJ-2-42
SJ-2-79
"
SJ-2-48
92323
10.50
92914
39.82
92939
64.40
92989
22.25
93105
51.50
93217
19.78
93592
73.93
JE-3-43
77.25
sJ-3-62
14.45
sJ-3-64
63.21
93919
24.15
94055
63.91
94076
77.25
94132
13.57
13.34
94364
94394-
20.62
94-402.
176.58
94448
5.57
94449
6.61
94504
7.67
94559
15.06
95033
9.69
95045
16.99
95169
2.49
95187
6.00
95201
34.18
95217
25.75
95381
29.36
95437
.5.39
sJ-4-61
4.72
sJ-4-67
38.47
sJ-4-54
h.65
34-4-69
7.42
95837
24.91
95676
10.30
95923
4.24
95992
3.00
5000
20.19
ITM4
Cylinders, beakers
Mice
Mazine bound
Anima food
vo. vet.
96013
96h88
96637
96700
AIDUNT
$ 71.18
101.17
34.76
Foraica, aye, nails
�
96778
22.97
Ice
9603
10.07
Ice
97302
10.29
Aniral feeders
3J-5-78
7.64
Needles
z�
95263
1.92
Overhaulin; typewriter
96012
19.50
Needles
99308
9.59
Dry ice
9.076
20.05
Aninal feeders
8,1-660
1.08
Tolel
2/7f3TC1
EMORY UNIVERSITY
ATLANTA 22. GEORGIA
OvIsIoM or BASIC HEALTH SCIENCES
March 28, 1950
CIFFoe F THE DIRECT011
A Dear v/
Attached you will find our research proposal for the year 1950-1961.
We hope your reviewing board will look favorably on this application.
If the grant can be activated as of June 1, 1950, we shall be able
to order certain items of equipment and thus decrease the delay which .
nay result in changing our laboratories. I shall begin work in New. -
Jersey as of July 1, 19S0 if you or the officers of the
tV..42* have any questions, I shall be glad to appear before your group
to explain or justify any of the budgetary items or expand on the
details of the proposed research.
We are proceeding with the testing of the-c Dpounds whichINNI has
submitted.
CCP:cw
Yours sincerely,
Carl Pfei ier,
CIIVISION OF BASIC HEA TH SCIENCES
-A- Dear
Attached you will find a copy of our budget report prepared on November 18,
1959 with encumbrances projected for the grant until June 1 1960. From
the report you will note that_that the grant from tht
is being spent according to schedule and will be used up as of June 1,
1960.
EMORY UNIVERSITY
EMORY UNIVERSITY. GEORGIA
November 20, 1959
OFFiCE OF THE OIR TOR
Payments are complete as of the present date, but _a quarterly payment
will be due Emory University- on Decemberil,:1959,
Enclosed you .will findirtN144 report for the first six
months. Our report of drug testing at. the Atlanta Penitentiary will be
sent to you early in December.
CCP:cw
cc:
Yours sincerely,
Carl-CPf M. .
�
I TOTAL
ACCOU J A1401JNT
9129-03
PERSONNEL
9129-11
FE LLOWS H I PS
9129-15
VOLUNTEER
9129-24
TRAVEL
9129-25
EQUIPMENT
9129-31
SUPPLIES
ROL
6
22,000.
4,500.
1,200.
8,590.
2,000.
$43 540.
OUTSTANDING UNENC-UMBEREDr
FAITIENTS ENLANCE JENCUMIaANCES BALANCE
(Total
ncumbrance)
20,994. 1,006.
5,500. 250.
1,691. 2,609.
874. 326.
67.
8,523.
400. 1,600.
$29,526. $14,014.
�
�
1,006.
2,809.
326.
1,611. 6,912.
1,600.
$1,611. $12,403.
EMORY UNIVERSITY
EMORY UNIVERSITY. GEORGIA
OFFICE OF THE CvvrnoiLER
a
,
Gentlemen:
October 5, 1959
�
We enclose the original and one copy of our
report of receipts and expenditures in connection
'with the grant to Emory University, under the direction
of Dr. Carl C. Pfeiffer for the period June 1, 1958
through Jay 31,
Kindly inform us if this report is not satisfactory.
Very truly yours,
.11
, I �
'..L
. Ralph C Davis
/Chief Accountant
RCD:dp
Ends;
eel: Dr. C. C. Pfeiffer
EMORY UNIVERSITY
Deartment of Pharnacoloa
Dr. Carl C. Pfeiffer Director
Suzary of Receipts and Expenditures for
th_12142.14_1112112t_12_12,8 thr�t101 FAY 312 1,222
Balance on hand 5-31-58
Received from Geschickter FUnd 1958-59
Direct Expenditures:
Personnel $ 24,880.12
Fellowships - 7,200.00.
Hunan Subjects 7_?;078�12�
Tlavel
Equipment
Expendable Supplies
7o7.01
9,703.39
2--318.30
Total Edrect_EXpenditures
Conitribution to Indirect Cost
Total Expenditures--
Overdraft- as of 5-31..59
(1Wbe-abSofbedbyEmory University)
* See attached schedules
APPROVED:
7- -
�
$ 2,156.98
18,202.00
50,3573:15,,
$_511465.00
( $ 1,106.02)
Overdraft
EMDRY UNIVERSITY
,ti,eS4,e.:,
, ., c %,-,,,,..- . ,.........�........ A.
Dr. earl C. Pferfftrc M. D. "Ralph C. Davit-
Project Director Chief Accountant
I 1.1:ye e.,):Sr.:1 -:d
expcn2:tu:cz.
tiES/CLe:::L1 ;Ivf.stcr.
�
Han Sal,;3ects.
ezie-
Instructor _
Technician Specialist
Research Assistant
Research Technician
Assistant Professor
Consultant
Visiting Associate Professor
Studefit-Assistant
Student Assistant
Stuaent Assistant
Social Security
Annuity-Di;
Total Personnel
FELLOWSHIPS
-Fellow:
Fellow
-Fellow
Fellow
Total Fellowships
I e9 sutzlittod
A
_cf
Dfir:sion
Data: "Sr )3(e-c---4-1:1"�#
RIMY UNIVERSITY
Department of Pharr:ecology
Dr. Carl C. Pfeiffer, Director�.
PERSON-Nig!
Position
Amount
Research Professor 4. 2,400.00
Secretary 875.00
Research Assistant 3,915�00
Assistant Professor 7,916.60
300.00
75.00
1,200.00
6ob.00
225.00
2,025.00
2,100.00
526.50
1/49745
765.85
38/.26
31.16
4.24 68o 12
/ �
t. 300.00
300.00
3,300.00
.3,a00.00
$ 7,200.00
2,c78.00
Denartment of_Pharnacoloa,
Dr.-Cerl C. Pfeiffer, Director
�
. ,
�
TRAVEL
4
Date
9/16-18/58
12/2-3/58
4/12-17/59
14/14-17/59
14/12-18/59
Individual
Destination
Dr. Carl C, Pfeiffer'="Frincetonu.N.J.
Total Travel -
' tle LTul.--Atted
Divon
Date: /6'
.
CK.No.
Amount
620(7
$ 130.e4
66569
77.20
739io
176.32
73912
180.00
SJ-4-22 _ 1142.6_2
L1G7.01
RORY UNIVERSITY 7
Delartment of Pharnacology
� ,
Dr. Carl C. Pfeiffer Director
---
}=1141.NT
ITEM
Freight.
AMOUNT
5.73
61.80
10.82
I5..43
Hot Plates
Electric Clock
Freight
D:ynamoster recorder
776.78
Carton Office Machinery
29.10
Freight
20.50
Aerograph with accessories
82/.86
Freight "
29.43
Freight
16.54
Electroencepralovaph with accessories
6,242.83
Metal Cabinet
4.19
Service charge
25.00
Seimicro polarimeter tube
30-90
Thermistemp Telethermometer
91.67
Integrateux Electroniquel Scientific Apparatus
312.39
Intergrater for Electroneplialograph
1,208.77
Freight

Total Equip-,ent $_2,27P339..
f E!..y6 �
su17:mittod
ts.ter
�
VS/CI.Ez:cal Diviston
�5-
-
EI-DRY UNIVERSITY
Department of Pharmacologt
Dr. Carl C. Pfeiffer, Director
ITEM
ATOUNT ITEM
AT
Chemicals
$ 11.33 Chemicals
62.71
Photo lab. 'work
7.65 Wire
11.80
Freight
6.09 Bulbs
9.27
Cats-
6.00 Dry ice
8.32
a�
18.00. Chemicals
15.20
Freight
:5.27 Office supplies
8.26
Chenicals
1.38
10.14 Housekeeping supplies
Filter strips, pipettes
33.17 cats & Postage
9.66
Celite
7.73 lase. supplies
37.91
Aninal food
39.14 CherAcals
25.39
Chemicals
20.19 Chez.icals
10.30
Telephone bill
2.48 Dry ice
22.54
10;42 -flats
Mdse. lab. supplies
10.50
TUbes-
62.30 Bulbs
6.3.8
Yaintenance supplies
20.38 Rabbits
24.72
Telephone bill
6.33 Chart paper
2117.2o
Misc. lab. supplies
18.38 Vire
"10.14
8.50 Ihintenance supplies
Misc. lab. supplies
4.52
Electrodes & wire
41.94 Dogs
36.00
Yeast
/1.04 Pharreceutical supplies
.48
Hydro:en sulfide
3.33 uu Radiodinated albunin
18.44
21. .16 Electric suppl ies
Chemicals
14.94
Infared spectres
11.59
900 Book
Cats
37.00 ------------Dry ice
15.33
Binding of Journals
31.05 Infrased spectres
9.00
Mice
36.70 Hearing aid cares
8.14
Pharnaceutical supplies
7.00 Tubing & ware
17.37
Cats
10.00 Book
35006
Tubes
12.11 Book _
4.78
Chemicals
55.86 Cats
36.50
Reprints
24.10 Telegram
3.00
Chericals
37.56 Publiching costs
33.60
Dry ice
25.40 Chezicals
8.29
Cats
16.00 Book
7.61
11k
Anillal food
68.50 Dry ice
33.98
Chemicals
12.51 Docs
27.o0
Dry ice
20.49 Pharnaceutical supplies
1.41
Cats
25.00 Rabbits
41.2o
Telephone bill
4.62 Reprints
19.32
Book
Tape dispensers
Cats & Misc. lab. supplies
Che-r.icals
14.84 Veddle value
6.86 vais
26.54 Misc. supplies
3.76 Chemicals
14.79
21,63
5,25
26.4
Book
Book
Mice I �
Continued t.ext-koll_Tin.
5.39 Slide rule
17.32 Lsz:p & con/lectors
tersd
63.79 . . r.r_s?ffitIe
6.13
28.17
13.61
Continued lo pace 2
,t
..; c..1.1
Taste.
Irre&14
Dade trane-alinase
Masc. lab. supplies
Reprints '
Dry ice
Chenicals; tubing
Pharraceutical supplies
Books
Chezicals
Vase. supplies
Want-au charges
Reprints
Book
Electfbn tubes
Animal food
Photographic service
Telephone bill
Chenicals
Photographic seiiice
Total
�
niORY UNIVERSITY
t_ tent of PharnacoloEy
Dr. Carl.C. Pfeiffer Director_
AIDUNT
$ 25.75
8.36
35.48
's 16.42
16.32
12.96
37.28
6.59
.86
5.49
26.47
13.17
3113-
10.18
36.00
4.70
36.81
I Lvc ' subzItted
r7S/Ctc=lcal 11:vis!oa
1",6-1
(7),
RECEIPT-
(f3
Receipt is hereby acknowledged of the following two checks:
Official Check No. 03557Z, dated 3 September 1959, drawn on
$48,378.00, paable to the
;volt B
., in the amount of
Cashier's Check NO-.--UT 5486, dated 3 September 19 9, drawn ca
$1, 935.1Z, payable to the
44.
Date:
in the amount of
.. �
z
r:, �
Z4 August 1959
MEMQRANDUJ4 FOR: CHIEF, FINANCE DIVISION
VIA TSS/Bulget Officer
. .
SUBJECT Z�� MKULTRA. Subproject 47, Invoke 110
Allotment 9-250Z-75-901,
1. Invoice 110 covering the above subroject is attached.
Payment should be made as follows:
Cashier s check In tho amount of $48. 318.00, drawn
_ 6 on *40
Casble ',I check in. the amount of $1,9/5.12, drawn
Each check sho1d be made payable to th
Alt",494'"Aa.
�
�
Z. Please forward the check to Chief. TSS/Chernical Division
through ISS/Budget Officer by 4 September 1959.
�3 This Is a final Invoice. flowerer, since it Is anticipated
that additional funds will be obligated for this project, the files -
should not be closed.
Attachment:
Invoice t� Certifications
- --
Distribution:
Orig t� Addresses
1 - TSS/FASB
TSS/C0
TSS/CD/
FY �
Chief
TSS/Chemical Division
0.0
INVOICE
CERTIFICATIONS
(1) It is hereby certified that this is Invoice 110 applying to Sub*
project 47 of MKULTRA, that performance Is satisfactory, that services
are being accomplished in accordance with mutual agreemencs, that a.�
detailed agenda of the payments and receipts is on file in TSSJCD, that
this bill is just and correct and that payment thereof has not yet been
made.
Date:
Chief, TSS/Chemical Division- �
(Z) It Ii hereby certified that this invoice applies to Subproject
No. 47 of MKULTRA which was duly approved, and that the project
is being carried out in accordance with the memorandum of 13 April 1953
from the DCI to the DD/A, and th-extenelon Of this authority in subsequent
memoranda.-
DAtc
Research Director
IF, , � .
_ ,...
, Si A.- . ... ' ..::: ...' - .:. 32 July 1961- ���� ����--,t:�-',. � :-"v.:�-�* :. . :�� ; � � . � t
... i .� .. � ",� :.4' . ...� � � .. ' I . . -. � .� :�. ;:. : .� ri-,:'..". -'.
��-....: �� i .
. ,.
- � %If ..:�".... gi,��.� .,...... ;
. . .11 . Z lie � & � 11.
. � .'. Z., .14. .t. ? .. " ' .� ' ' � ; . . , .%,"' :. � . . . .. � : ....0. A: 1. � �
� ; . � � ' . 1.. * : .... .41'. Si�:!�
: . ; � 0 S .. � � : 4 . � rr ..7-� *rri �
� 7.� .....44 eCti. i4r.�
. 4'-.. � r� il?..:: )121-1. ORANDUAI FOR:--Chisf, linanee 1Dirtrel
?' oe. -- I �
.. - - ..1 . % ..* f, a s...ir:ir �-:::....-
-. ---.-; -.;�-.. -...� -A � � , - .. , .� A.:. ....... . v� ' -'� '-* - - -� ��-�-� 4-:�`.-�-�:�' --'4. ; *I� :t -c,'': ....4..� -:;.a� .;:' ..�:;:c.- ..-..:- 1: - .., -,- ' ,'1..T.'...;p;�.,,4-"��:Vz.. ! * �- . � ti-'
-� � � � .5 ����� � �_ r...
....- ... 0 ���:�_.---...�...4 ." .-r� �� ,--.7 -;_. ,..: -4,.....4.� ,A) 1. 'RV 1,1�47k �� � a����� t� SI- . � 4 ... ' I � ...V , .� - Ar- �
4.-;,:..Z-Z6�A'' -VIA - ,,,,,,,._.
-34,..,������.......,,-,,,,, -Jr..:
_ --
,, _. � t ripintei Offlo 3 r
--. - ..z.. -.,,... � .. - - - t -.1. , .. . . : ,� � ,.. .� 1...� � � .�. . i,....t1S:::.:�.1,21.,
-T -- t.. : .........244 , . .. � Ir.' - ..1
. 2 . � � l'- .� ..- f� -4..� � A' �� 4 t ,.... -: ...N.i....A.,-... -t_t� .....17. �-�if.... ..... �.. . ,, .... _. ....z........... - r.--.
n N ' ! P'' � � - ? n. i � ' '1 b ��� - SITS ii�-�.,CT .. f� � . .....�.
�-',�-��-,� -� t �,��:. --t�-� - � .p
-_,---.?.:2�
-. S.; ,f :;.� ... r:
����� r �,.... � '-
..� .r.r. s ..: ,...,.
,...
. �
-
.S44;4:
� . � .
� � � �
� eio. � �� �����-.1z.�"�;'..
� '31 . Ser � - , .ar
� � .4 : - �
� �
- -
�c�
������2.-�.C. � 4.�
. ��� ....;���:, � 174- .��� ,relf
eV,. 1..4�1'W.T.4.
� - j� 17 ' " � .
���� ; z
�"��A� - � 1:
:
��
'
liKULTItA, Subproje-et 47. Invoice 210. 14 *:` .*;:`,
...,,-: . � - - ..."...4 . C - . '
it: 7; 4.::.,.- . - . �-- ' ,1: 4� Allotment 212.5-1390-3902�- - .1 "` : -..... � 1 ; 1...--1:-...... :�.- � P.- ?: 3;.--ek 'I!. ..4:-.� : '
-�� ��. �.,..-.......� -...-r�
.-. ., . ' ....P. �: . � SP :: St r S St,. .
..... � frt." � . � � � � �� �S � e . � .� .....r. � � �� _.. :. ..4 � � � ��., rr..t . f. r r
11.4.;;Ire4rs t.
� ...3.�������:.� 1. 7- --� - : � r-1-; s � ' I.'� 1"- 1".�..../ : '' -ip �I. � Y.- :......0" . . � . � J., � � �
: . . . . .
�� . � - .. � � � , � ... ...- � r.'"r- . � ;�� � t . � 0- ��� ��� *s� � :
..,..../..!::�"Il�`�'.;:"...,--;������%,.-".-
;.
-Z.:.::.�:;,:....- � nt:.1. :-:;,..:'2*:: :%.'.1".."- -1.. Invoice No. 12 coverlag the aboye sulprojc-ct is &tftch
rS .. I. �� . Ayment should he made as follows: ,.- � -� --:��� ... � � -%.*k..,!
������ � �
�
�
�Sk * . � IP
At
F.
"
�. � II
� .
� , � ,-����
.�.....,.......� shier's chetk in tlie amount of 1.30,740.00 1.1K1..ven on a-- _ �' ;:k - �.
....-- -,�,y- ." - ,:-..i.... � .. .
.� - ' 7.:.*:`!-...... -
.. .�, .
� . - - , 4t-nnale-�,�,tiglea' t..".*V.,... � � .-- ..
' � .., � �-� :--e...-�� J.:1 �������,..,---.:
it-4. ......-,-...-4.,
---.. . - -- -
--7:-�.- - � . '.... '''''''' '-'. -,
:X.', :,...�:'_44.,-�� ,-,�� :-..! *" � f..4,� . ' t' '. 7.v. . r--�� ;,��� � 3.... 4 -s-'--. ,..���-��� � : rf� � .. ..... r% � � .. i : .,;: . ; � . ...� II �:.� . � :s.: Z � ..
..,_,....c..=-:_.,-...y -- - -� - ..-- .- Cr.'..SMeria th_ 0.. h itl MO .3t01.1X ait �)/1.22961-0 cli-awra on & �:',"- �,� ., �-�
"-kJ,. ��- . r , . . � ...--;�. . .
.:'�.--..---- .t�t..v.N....Iivvto�-� , f---r9w . . � . ... . . . ; ,:,� .
-A-0. ....,-t, , .. . .
.....(e4, '
-� - --: �:- , - . .
..
_
IN�-'!....-1 thCA.11 a bAtt -mz--1 a_ mall� to the
.�..-* --...7.---.--. :.,.,..�::, 's � - - ������ - : ..� ...;; �, � ,.....7,-..,..
". � � . �: t .
%�
...
... - ..- a- - ..-:'.- .,:.. . � A. 7,,...q. A . _ . A A ... , . ..., . .. ....0..) ,*�-�-art, a ..... � - ....e ���� r� r � � -- .7" * � � ..� . .. .* �:". ` ; ....4: .: .! � ".:',..: � n � , ,r, �
- �'
...... -.-........ :., :,�_... , .; .,.
...." ,...p ......'
:'��� �Ca,. �..� ..:' t`''.1% :..'. --*. Z. . Plezze forwardlhe_chocks to iChief, 'I-SD/Research Branch ....-.:-.=.:.-:-
....r...4.; 4.7.:�."72- ..-- ..�.: '� --:- .
--'''...: t�'-k.-c'Iti.-4:�-.3;:�-f:s47.� th'IV. .-13' TS Diale.250t CVn cot' by 2,4 July 1161.. �����:-, .. . ; - .,..�.��,...........,, ��� ,
: . � � � .. ���. .., �.�::: � .�. :�.:-,,,k..!.-:,
:�������-.-..-�:.;;:.�-3.-- 3 .."-� t. .......,, �-�� .- �- �--: 5 -1- .- ... �.: . - - .- ..� ... -. -.� ,.. - � . . -.. ' 7; . �i..., , ; ; --:-.-� * � ' . � 1: .. ' . � ,�� ' ".; k:�.'"`
�.;:..... .. --,.... tt.. , . . .
-..,- ; � : .7 f.. j-,.--..;,..;...�,...7,:..t..s . � - :: . � '�. ..-ot*.z *.-.'�.T.---. -: ..--'.. ..� ..:�.-. :',."` ... . - ..7.-� .�. � : ". A :-. 'i". '�."7. ....7- a...1'4-1:,:-.7 ',-� ,
- . . �:. " � : .7,.-.-
..-:-....�.. :. 4: � . . -.., is�
- _ .1"
� :,..4 t.,!...ft.. � , 'NZ' � Jgr� �-�thle lit a, Cat Levolce. _I-ketrevor, since it Is twiticipD,tott � -. .� ,---
..- . 4., -,
� .������,...� - . ./ % - -: �� /-
.,,,,..-_-�th4.. at.bitional ftmds win Ito_ 07.)..11---4o�ci for this project,- the fil0 ' '-'" r".� '
:��� .
z..._.:
: -a:..-` . ttLattid. not. he cloaed. ..
,'-; � � �-�.: -1 � '4 ' ..' :�-�':�t:
. � �
.- � . � ... � :� 3. � � , . . 'ZS.... .7� "'
..�..14 ... rt PI a. t:����.� f . i -� I.', f.:s. :' I. � ... '..'.� ..! � ..� , � :: � .�:. � . - .
-- : �� . .�:....� i- .� , : .' S 2 ,. s!. : ``. . .4. ' 4. � ��'.
- . S,:- ...S.% . .. � ����11 .. i� � rt... :". � i . -. , . � ...' � --: Z. s :. .- � ..4.71.�`�.;�....� � r ' r ..r., 11/4 :. '� ����'..a. .- .
�r-t.�� t. �!.. . n �������3� � :. :.�:!����.. "t� ����-.......t'.....38. �.:":::s-:-:-.--..:-�
. .
, -: - . .... .., � � - � -.:-..f.---.,-: - � -... , � ' �:- c. � .- --. . . . .: , . -. � . � �
-.J..- �
- - -
. .... y -:1: -- . :-:i. - �: - -�-� - '.� - ' - . �''''',. ; � '
.., . -.. . � :- . - �.. �����.-, � � � � ' � �-� - ... -. - - ' - �-, : ' i
..! � �.-: :.� --: � : .7- : 7.-- - :"' ': - ' ' . - . : : "--.' w
-- �����-� ��� �� �-�. Cliliel ,,:. _ �
�...e-,... --........-�� : . .
� - � -.,..... .���
. -. -.-��-�.: .. � � . ����� .�
� � .. � ,.. t IV � A � � .. � � : � ��� i . . TSDJYtes e4r-clx Brench � : , ��� ;..::*--,,-
,....,, � -: � - � 4... � �� . ,
....�., �r � r ,. �� A - -. � ������..:1,. s�'... 4....,�.*. ����� ,... lb . . � ������ .
+R. � ' !. ' -� � ' � .. I. t n . � ...
. . � . ..� . � . � . .... �., � ,.:
. _. .. s
n'::�'.. �Atta chod: � - -� i-�1';:i.��'- *. � ';--'- � -- -...0 MEC Kz."-ul)fi",$) �-:�� : 7 -,:i ,r1; r.,,,,c. ."*. ,:- ;A ' "z, _,�-j .
.. � � -� ...
-.....�
� ,
- .-..'-- � Trivc-lco 14 Certific�t1Cras RECEIVEi:%; ' � '' """ 1.
..� -
, . .
.' . --.� - ::: � .
� ... � .g. A �-� A,1,.. ��:if ��� �
. . . ....r.......,.,...�0�,,,,,,...................,......_ ...._ _ _ __ ___
� � . � � .�.; -
��� .
013 tr 2 -
� � � �
TS 0/ FASS
TS'i?/RE
-
� rTSD/RB
! --�--.-
� � ��� . � .. ��� '.�����
�������
... � � � �
A � � � � ...rip
��:" � � ��... � � A' � �
of:111
�i�?
Qz _
�
^ . g ; 4,����, "
laged.?"6:1'�"re. �
�
� ; � "
** � � ":...!�-.17.`,47�
�
� : .t.Mr."13tfi bF:
1,� -� , . � ,
� � -.� �
- �
���������"
. � �
-.or- I. . � IN �
".
j�;�Vs
-�
--4�""�"," It-16-Prit . ,4,.....: *I
6.,; 1 " �1 ..:.A.--- r�-).. '.1 �
,. --k - �si,-A- v. -4-.411 " .-/- - '.�;1:i'
� ,,.- � ,��.,---,1-V- .Sit.,,..:1,!r,�;�,..%.N, , .2481- t"N'.1.1:7`4.:�_(:::::_-:-!:.-:;:st):,7: e. ..'r- ���-n.'.''.�-" ... �� ..... �-%:'-'-- - 10 "'"':���-�-,1 :1�:"%��-ki'l-rls`;31:`'.�'''...;.:';'-f..t. .-;(''''i "a:.
,;.. 4.. -,...c.a.....�-;?t:;41::Z .�"),..25:-**,�tp",-'4 ,..,.' ' 7P.77s,;,..,t....,:..Y.4 7 i � - � . 41..-,;,,,,r-.."�"*,4 i : - .' �����"..; ' -.. 4. � ....'-
...,,t.:.�,....- .......�,AZ-Z-,`A 0 p,A.:,1,4..... ---,f2t7:� *-7:*�-�:: ..*�... 7 '..,',.' "..i... 7 . ''' .. ' - . ' " �����'. � . '
;� .7 � ;���; � '� � ' .......i ����`*��� � *
, ......,,,4�........r ......i.:,..4 -:-.. ,:.- 4, .a ---)?.... ,x� ��� 2-�"� -t- --s - - '''',.,:';';',..
;-*---S.--"',..-. 7N-'�-� ...7' ' , ,� �,:.^:'.!;:. i'..."-7.-1�'� :' ...--... 4 t.
......41. �:.. � .tt...7",.'-ei�.--;;;K:, ...,....-..-"3,-.� *.i .. .:, -..;-:. .4., ..."...":": ' 7. ,r,.....
-..-4.----.4..N. ...,f:,----.: -..� - - - �-......- ..s... tr. ��� . *.., 7 .,,-, ,, . .... . . . .. �
`..-1.-"I:�.:1 Receipt Is hereby acIsZovledzed of the follovingt
.-.A:..-r.4.2',4W: AA If"�`4C:�,..ei �-�4�3C...S...,� 4.�� al. ,,,r.. ,� � 6.- ..'� �� "....r..e ''' ������� ":�'��''� 1..:.." � �� � � , ... E. . S .
*If t-���� �
4 '�'-.; :..i.:,..:::..�.:��,�....1......7" ..7.17.���-:;:=-...:7.;:-:::.-!,:, .
.4, -...t.t.; .........-:�,.. -t..i.rt-4,:i�e' .1....f.,.. ..,,�.--..r. ... ....,..,�,c, -% .....:�.;;;�- ,. :I. � ..4.� -�� ": -: .,'���� : �� -
-' -ri- V,?..-...,. -_-� r....-1; %A ',.,;7, .X. -..4:::"/";..;,1...... ,,-(1...7;;;-:. -...,�--� .: ,..,..:-.- -.. � -4. . ..- - , am � ��� '. .'... .
I.,- � ' '''-%'.4-...t�.1". A., ... � /* ..' i
:..� ' ' 'JX'''''. ''''''''...7'''..".; '-f. Oftiel al Cheek 'To. G 33.737A-.:4teil-.. 2 --July -1959 , dmayr,� on
...._._,,,,,...4_,......._;,,....:....__�
..
-:....-..-7.-...... - --7:-,7L ..-.... - - .
If, �.7.-... 32,134.67, payable- to the
4. � -. � � � . . '
.�_._
.sr- L.A.& :�-.s; I.,
IP . �
''t-i-
� -.-,.. - - , . .1
' - f-f- --- %Iv- � Of 'i icial. Cheek No.' 0 dated 2 July 1959; draw, on
____.,....0.,.$�(5�,,Wr f. 2/ in the amourit Of - .
- .� -
�,285T-..39,. Payable to the
� ;��,-�
-
- 7 - � -,.-.
-
�-� -* � � 1
� � -2, �
. . ��.
- : a � 'e :����� . �
� � . ����?,
' : � -
','*���'-'"'se
� �-�. � ����
'
:AVM
� . �
� , �
s � -1
� � � �
, � �
s�;,
�
� t' -
�-'1r
�
� � � -
�� �
:�."!���� .
I" �
� .14 � �
�
� . .
� � .1 ��� 414 �
�� � . � ��
: � .4.m,
�
-ff � 4.... �..-..-.1,... -A, �:���� �� "*�%��-�4. 2, ,�..�,�.:� 7 � --.: ..-. . , . � � . � ..; . .. ., ,..!' . ' .1. �����6.� 6 � ..r..r7":
-1; s. f .1..." . � � `r -41-. ca.. t � . ..L� .......--...... � e a a a. . ..� ''... .. �, %A, 7, ,..* . �... ...,
....�-:-Stin JiCt:1-.. -_��,"--�-.X.-�.�..:::: . :1:ik' til,"-i RA � -Subpro sc _ .
- � --i� �� - -�---1--� �..,-r.1,-....4...... ,
.-- - i t 47 Itivolce tit-- .7.,:- ,...-,� � -:-,..........., ,
=.p-- --s- __ �,-,:�-�,,:-,.-, ...,, ..,.,......�_,..
-�:.-:.i -,----4.4. - ,,,� . - F � � � � : , ..-1,nr."..!.F '� �� ,:si -' �-��:k.' , -,0- 4-.1-4 �' tk.-11.1...� ' ' . P"
' �.. - i � - .; - et- .... �� ;Lie"- "��.*P. -rt.* � . "�'.... 4. .k. ....";� � , ...F. �:"...; - .: la.. � � .. . � � � -._........a ....
"a.,. -....
* --4,74. �-�-"'t ' V.... . - ..-..-- . .."....... 3,-1�- ..,..t... ......_,�.. �:;%.,. s.,..._.,,,....,,_-,...7_...�4,�: .._,� it .... ,44�. : ; `.......*... :ay. .:..s._�...s._� le...a.....�.g : ,, �... ;1.1_ :. � :�'' - _Jr ,.,��_"�, -b.- -: .���� - � : ���� . _r_ ...�4,..........A,....-.....-t-----,-,...,
. �-� ..... .
: 4.....?��..?..3:-.........i...:_s-,.,,,-....,..-1....r.......;......1. �.7..�-.:-.......-.4!;..,.. �i....... ,-:�.!�.�0.-.1-..t.,:izi, ,.;�...-4;...�.:..�..:....�,:��;,";...-4....:.-4.. ..-...4.����:.�,.;-.�:::,.....�'�r" --..:7� 04: .11-..:....:�-�..-_-..,:ii: .f.:.4..-�,:.....:...r.-..-:�,,.4.,�1.-C, ... :�......,,-.-.;.,
!I:A - ---4-/...v. ".�,t.r-� 1 --Invoice 111 covering thiabove subproject Is . i-,-. --,-_,..-...-z1--..c.--- ; -
. � � , ., -,-.. .:�-.,. -�
.-..-,---;,si..1,4�� Payment should be mad* ais follows% ' '-�:.- --;�?�:';',� - ---'"-----�' .� I. -15- i--`
:�...101...,...,.....,.......��i�....,...._ ,. ,,....�.....: w:.....:� 1., � .���,,,,-(..�.�'-z;-..2-11.--
--�.. -*A'1��*`-/".:: !�:r.. �.***1 -5,���..!,�'-v'...:X7.4.Y.,-:�:.'tr�s�"*". 'Ie...." .---:'-:. . 1 . t. ."...4�-f: ;1:::::-414% .9: 1�35.41 0.-1.0,1d1:-r awn . �
---.-� -- - _r. ,i..,4 ...� �,.....�-'::. i�.k_A!�.�,....>� 7!..-...!�-.41-.� -1....,.........* :!...:...1 ft,. � 1.." ......� , .... . � ; ��� �
. ... r '1.'4-' -''e � i ' �'-!' ' *� - ' . -.---ti lc Le the trrloun co a
;.;-�-�?�-ts-,-4>I� ,�-- - - -.�.......r.'y Ct.' hicr ic cc
A-
catia-tv�.�,..=e4t, . �...in,, 41.1�. '7: I :: . ;..."*.fi. .:��t-::. "-a rv.�: ... '
v .�
....:;.:AZ&N.,-.,..itil:.,,,. � 'I
....C'75V4ct--"f� ',14,,q.:;�-tl') et.,..,-},-,;4: 4
.=-'-'1,!.&1�.,,,--7f..h..:�N-�,�..�-q4-1--,,-.',"--,4-i -11)-4--.--= 4 ...,�0" )
2.-�-����:;,:r..�,�-kN ---.--f��-.; '..Y.T. --.v.---......'f.el 4-'43-� keis,,-1 ?;;5` �?-#. AN .,�-�-��� ! ��-4' 4.....*
4.-; . 7.1..i., ;X*
.',...-k!..--, 6t, sAA,:����2�*-S,..e.er.f-A..i4.:,-./h.4- ,..*%;;Zet-it . - al:A . .
�-'''i.1 .V.:1777,P!'-.4.-;Irw---,,,t-,---,7=-='!...t :Iv& ..2.44..S.re is- - � V--". .e $4 f-if 2 .`����� 4 �ot c't (�� ��������4"--** -
.- i'; `P.- ela":"tti-i�:-.;*. zA1"5::";�C.;.--'W:-� a' A ri.5-i" , :�...-4..f.1---., ,,,.--.. . .#:_ ,.. .4. ,...-;..� ........v- .4-.',.
4:"'re'...i.e.::"..ktlie-i. II riZ,4�1,1', �-,-*
,,, ta lc, -'?.4-.,�r�-"drt ---.7:4,:ie-..r., -7:-,v�-r,;. to.......�.
--.-,-rKfN - �- te�--...-- .T. � 2��������7,- -..1. ' 4 !���-.! ' .
� '''.� Jit i1C. (2_46�...r 4- s ���� 1 r t'�-�.-� 29 June 19 60 :4:4'1.-;,--VA-'? If:.
�- -ark-- .S.716 _ "Ik'e,... - .4'.-
� ��� . .....-- � * �,,,N, , ,� ...',N li .- A �=z7.:'.0%-:}c..1: a e- � . a ....: ...v.,. .
- ��:�"' - � ;AC,: �� - ...� ....... ' � : i.,�� i..,,, � . *. ..-. 3.1�.�: -.-.. � , 1.1 i , . _ �. � � : ....,� -..a. � ....... j.k,
' ��� -� " � i ...' %a a.: . � � . � r I. ,..iir,, : s:i.�����;: ,-;7.-, ... ... -,� � � t��� ."- , � �,,.... ......,:�:�� .7. � .�). . �
? - � � � � --: 1.� . �-r. r- it. -...� A. 4..
� - '��� ., --. � .N... .....�
��
VOR: CidEF. 'FINANCE, DIVISION .
ORANDUM .� .� . - - � if: � �:-�';'�
, . . . � ����:-.11 41$;,�_.����
ITSD/Butiget Officer .
�14--�������if "%te
dc, ,
- � AR � .
:".�. � � � vs
�

� �����.- . � � � ''���11; �-����:.'�����;�`. �
, :`����-� ;,-A110tri � mt. 0515:1009-4902
0
�� ��,, � r.,�
� - � � . ; - t* � �4".�:-� � � " � � � �� � � * ";���'
- ��%�."-� - � � .� �."`� "����
ca411.181!. :check In the .mount of $1,979.91, drawn. �
"
cr-1 �� � - 4r, # � -
1
A "of.-11...�.. sik. �
�:-���on
'tack check shosild be enade payable t-o the
�eir':��"�471,-, l'z.-!"'����� z..
. � e. . � �� ��� � � �
: `.� Y.16'
� � . � I . � �-� t
, . . . � �
� . � ' � � ��''' -�
2 Please forward the checks to Chief', TSD/Research-Dranch . �us.
"-�throt2,Th TsD/Budget Officer by 13 July 19600. . "���� �:' r� �
�#�����.���.*' 1!. �*-� ��� ���!- � ������� �-�.�
-._ � .�� - ��-� � z(-..1 r � � �� .-1 ���
. . �
3.. This is a final invoice. However, since It IS anticipated
...:�4........ t
;"..cikl. .. I r ..i: � ID �������....r..S..1::. /I: C. 11,.0-a...r. C..14..13: r. a..17.,G.:1%.t.....T.. � �
._.....-: -
:- : 1, -.-,....,-� . .2, ....
� '- '�ts * Attachment: ,,. � .4:-�,-r,..
-.�-��=���,..-� ....I.-. . - . _. ,
-�,-.0 - -.
. n ...�-....7�- .
-...t..
� . -i-.... �.; .� - - . . �
...... :...- .�-:�. '�
''' Invoice 14 Certifications_ . -....; ���_-; :,...r.i -
, ..�.- : tr.-��.' � . � ' - t� � � � �. � - . r . � - - tr ; . � � �
� � - - - ...AL,. � �����-.� �,.. - as., � -..;;;.�:"..�:. �-... 15.7.,- ,,,�..- ��,, t, � � ����������� � - . . I jut,
� ' � ." ,,, t ..c�-�%. -.-....; - . i...-- .. -. ..2 -,2-.-.."...--� .� ., � � to -(..... ! t -*". �-�, ; .17.1� 'N e..� ....t,�..-: .. ...:.-'11. --�::"���� IIK"
-c,4 a - - q , i .1. : � .': : : 1... ". � . .
jsr(,:v;"DI3ttibaltiOn; '''.....'''. . :e ' , � . - -
,..........r..... _ .? - - � . - �� . ' . �72. .,,,, , ..;�... �-� .....: �..-. � ...;11 Cititil MAT nitic..,s, API AVArt.A5
..'-
.....n..., s , .. ",is k z �� Add ji� c A s. it. .3 _ ' . -1, ,... .� ���� ... ...v..... '� � �........:....._�1/4,........)...44,;671.1".3..�=.41...5,....twit62.4.
, ..��, 4
� - �� .
.'z'. , .,. 44147 . � .. .� . . -TSD/FASS � . �
. � ��
� � �
r-4),�t.----.�:;.�+,�;
7 -`Z �. TS 1)1 RB .
- vo.; � �
. 111-1EL:rjr--..� I.:: ri J. iiir:'.� AMOUNT. LIF.
t� ;1.4 �:�� � � ��� *on..
V that additionA1 funds _will be obligated for this project, the files .- � ����`�
- - -',1%.� � a A���� � � t. � � , .�: � , 4 ,
.1�;�-��� .7* ;�:',1
; a !
itOnid not b "-cloy ' � � !�:
Iti At4C-1.1141. OF � . ���
� '�-� ����7..,-- �
� 12_ iJs.ava _ ,� � �
� �....r_d� �
� c
�
--;:%�4; -.47-*AYeata� .
�
e �
RECEIVEID� .7� �
-
- �
.� �,.�� �
4.7%; �
� . � rat*C.1 .".11,:e: 04711 p.). f p
� -
: ..I;nr�;217eriG Oti
. �
. � � �
� � . � A
��:� ������ . �-� � � t ''����;:- � , �
��. M �
� �����.!"�.� A � � �
. re 4....
� %-
. P .� � 6. � � � ��
� � .%6.� � '
-� :���� ,����
�f�-.�
a � � /1 - �
sr a. ":"� �
- � . �
�..,. � r
- r � -�� ��=�.- P .6
'��7
aftEr
Cost Account
Object Cia
.._
Date

Remarks and References
Obligations
Incurred
Obligations
Liquidated
Unliquidatol
Balance
_
22JuN _
.-.-tsso
__
faj, � 6,1_
1 JUL6
yi. VIP.,(� VII
�wei-- ��4
y,
_iiii_ft �8,1
..,
4 .
�
..
_
_
:
,
...
_
�
Cost Account
- Date
Remarks and References
ObligaCons
Incurred
Obligations
Liquidated
Unliquidated
Balance
LAI
II
z f
,,, , d
eez_.�je_ 7
� _co 3+3.
/
22 IN
_
. ?
� la"- �:. - - -
/P
-T---
%.3-g$
/ I
-
----T
-
-
_
_._
'
-
��
.,
'
---SE-CREF
25 Juno 1959
MEMORANDUM FOR: COMPTROLLER
ATTENTION Finance Divieion
, I �
77- V7
SUBJECT : MKULTRA, Subprojeci 47, Additional
Authorization No. 7
Under the authority granted in the snemoranalum dated
13 April 1953 from the DCI to the DNA, and the_extenslon of this
authority It subsequent memoranda, Subproject 47 has been
approved and $50,313.12 of the over-all MKULTRA project funds
has been obligated to cover the subproject ,expe see. This
obligation of fends should be charged to Allotment 9.2502-75-902.
APPROVED .F R OBLIGATION
OF FUNDS
- -
Research Director
Date: 3 0 All; 1952
Distribution:
Orig 1 Z Addressee
TSS/OC
TSS/FASB
Z TSS/CD
TSS/Chemicat Division
I mitt"( THAT FINDS APE AVAIEFEkf 4;4?
-
OKIGA7o.S/ ktrrne:Cf N.. I 4^
1.4
CliAk:Cf 70 A11011,1'4' 74.3.7,�:oi.Trs yo,t
,
SERV
AUTHOR!ZIuG OFFICER--
.
(When 1..44-041 In)
CONFIDENTIAL FUNDS POSTING VOUChER
VOUCNEU Ho. 7.42 I�ATE'
2.6 IYOUCN R NO. 7.11
I
C PTION.ALL T CR ACCOU 1* 1So33
suroom
143 lc. , 017.52
40.4a 1 '1 '...41 06LIG.
2
56.67
06.57 I ALLOT. OR COST
6.701
DUE
71.60
�3
CODE
EXPEND
f
y !
PAY
REF., NO.
GENERAL ACCT. NO.
DAIE
AMOUNT
: OESCRIPTION.
ADVANCE ACCOUNT...MO*2T
t.0. No.
040P. NO.
CODE
N
00.
am.54.
CAI
LEDGER
NO.
N...n.
0604CT
�COOT C�TO I T
WOWC7.10;71.1
IV
:
CID"
. (MP. NO
ACCT.
i MK,. NO.
CUASS
e fli. VrT Y &I
!
'+' ,'('I-
4- e/.e
....-7.2 -..cdt
.1 .
1/,
.2., l',.'
3 ..
Ar-
� � &&&&
V '.a.: ',/ 9 .et
1:/:-./.1 (..
. . .
� �
s �
& �
�
f
/
. ....d
/ �:���� ,(2'
44:.4 ritL
rI4-
. .,
. .
..
,
�
�
�
.
l
�� ':
;
�
� ..
.
,
CXPL.ANAY ION Or ENTRY
TOTALS
.
._
�....
OAT. .
� CERTIFIED FOR PAYMENT OR CREDIT
PREPARE'S SY IDATE 01C111CWEEI SY
I ,
ISIGNATOE r r
0).6...T.E,,
FOAM I
, $.5, ,606 use PAAVIAVII 4AITI001.
.�
(10.46)
, .
;AI
.�ce
I,i *.F..4;g7:3,:ir --,
.1,- -�...-,',41, 4`,ret'� - s � - �
l--.1" irq. .1,,...,_----.V74.1 1 --Ic�::,c- �--, ;0.1;4 ..-t'� 4 .4.41.. - '..:ri,-.-. . .�
-..v.-7�, F.� S.- � . '... ...,:k. ,..1".......,... � ' 1.,';'161 .1.: " �-��1/41.1' -.�� '.9 4
.,�� tr. . 1, � � .";t:�.7.-1,� �� � � -.2. Ai- ...so. 1....:� ... -
-e. ...1 .
r is 7s � � SI �,�_v� 1.17 .� s' It. .� _.
' - � � .. � : �., r.,. 4 1,1, ,r, 7 .,
' '''e IV� '
7 k � �:,-.v.. ,c71,...- --. - ., -4 � � ,-�-4-4, .... - - 4....--r. -1.--7:.......r.:
� 4 :�-- :-.' --- 7.:-.,,.--; k�.'1.." -....' : .....: ' .4 ..*: , -. �e.--�' p
� � ..i....�.�....114......., .., - : � ...):: ..!'*- - � � � i'����.: f.
�ti -V.�-;-4....- I.... .; A. � -.� - - � . i!....- .:.:�� �. � I ��i,A, . -,..":1.-.... . ��-,,
S.
.�.� A. -,0 :A.--,..17--;,[ s if-- " %�,r.% ..,,,,�:*`-4.t.ii".;� � 4 August 1959 � - I.; .---...-:-��:i4t�-:��� ---r,4-
,, ��.-1..�, � .t...�
--;es: .7----,;":: .:-- "�� 1- . .-
-.0"*. :
-�V,.; : 7 � - 1......., ri . �r..� �., 2 . ' : � . :f. e...-�.. " 7. ...Z...` ri �� -"."'
� . , 1 tir',74' � � -
---,ft,: S. �.! -, 1,....:�:. � l ''.. � .� g-4.�-�� -, .s ;���� It : . �-� = : .. � *.� '� .." .: � .:'� � ." ie.: $,:f� i-:. - ..._
..
.... "..:7';'>::::: �'....-:4.1e:H� "V4-%77... miZ. .:- 4 4 ..,.... ...X. S 4....:-J .... s officer" - �
ILAE1�10RANDUM FORts-C�1-11Cf. FINANCE DIVISION. -...-.. �,;-;:,-�
� - .4-9. � "E �
. At.. �� 4
.., (..:4w.
��� PI ' � 1- .
i-.4.....W1:47:-4'. -rflr. 2-..--:;-"-' E .TSS/B u� g et
..,......-..1., ,--N.,-,, ..�......_..�,,............. ....- � - � ,,-.... . ---...' .� k!.,....7461-161...,.....
z,,,... ,-,.t.,:-.,--.- -�- -0,.. ,.., , :. . � .- .� -: � '-.� -.-i.-,k -----�:-�-t-z- -:.- ---;1-'7:---,------ -...:
- ...., ...:..-.:.;� . .,�,. .. .......-....:
���:_��-:71C-:' =V Ir.; /4., 7... '. .e. � ��� 4... 'it- �� -
'IT.. . .... Xiicill.aft A, Subproject 47,- Invoica.110 ..,..,.'. .-,.:.F.:�..,....7...-,-.- -
sunxEcT -
, �:.4 � : -irtft- -- ---. .,,:-.. Ailotcnent 9.250Z-75.902 ,.....�,---,;�,:-...�,....::)..:--....,..7....;.,
----1%.": � ... ./....�!....�,..,-..v...� -. 1-�--...s.:-.:-...,.....-: ' - � -f� � �-�-:�.4---.... -
S. -- .. .. - - .--,.., -. .. - � -, ..-4:,..1,/ 4 ' ���� � � � ."...... � :�
�
4�:-Z4*.N:-.11'
�� � �-:.� r - c0* � ``. 4 ,...-. '.. �-�� !r--*".�% --='!" 1,- i ''.- '- :' --��'' --' - ......., ...
-.4-...i.... ��
trz... . ��� s' ����� ..,...., .....M . Al .
.. %Is � �� �� a. .. �
�-.1"i2;�-"�sl'; Yroill 1.4, -it -.4. e.- -1',.� .:.;',.,:�.�� ,-, . ..... :- �.-... � , ; :--.-,- -k- -.V
Invoice 1110 covering the above subproject is attached.-'
arnent shot.Ild be mad* as follows: �-� = � �
� � � - � . . -
on
. .
-"e �.� .
cli in' th
eck mOunt .o.f.
� -**.���
4�-
� - , .4 . : ���
... �
� ' ^ �
ibount of $1,935.12,. drawn .
�� -.4
: � �
.** -����it',�����
�
.... - -
. . . . .... .
---.� ach check shOuld be made payable to the
--_,�-� - .... �.� .,.,
. . .. ..... ��., -1�-..�-.
�
i-i- � � I� : a -`..4�7 ...".�::� � � ' - �
. ...... � '
�r� .-.�.,ei.- .v. �,-.. -:r .t...-1....,....� .-;.,.. - .. ._ .- � -... . -..
' ---�-�`"�--41.-4.�`-... ---. --Please forward the chock to Chief, 7'S-5/Chemical Division -
---�ft.N.;;-(:-.1-�=:';.:-...- = -- - .. .�.:
.-.. -.�---z.., .t.ttiough TSS/D0dget Officer by 4 September 1959.7' '"' �7.*:
-�� .-4.*:�,4 ..� ,.. ,
-1,',"-!:-;;;;:.�__e:-,.�.7.�.� ---z-,;:�.-e.r.. t . -:., , � � . , - .. . � ...'1�-..' '�:�--:-
....-e-,.':-�,...-!,-,.;:,-� 3. -. This is a final invoke .110WCV6i, place it Is anticipated .. ';;;::'':';:--":::
-.c..that-addltIonal funds will be obligateil for this project, th? files -.:;--... . . . -, :- "*.7;:'-' : :' . : - :- �
.. .. ' . ...
ii7 -...: �-�-�' :' ihould not be closed. .� -: .
..
- r -.., S'.... �: e � � Ne :.. , � �� ',.�5.
��
V�� ..i.". �:4�:z.z.k-�
� ��;������:"` �
������� ��1`.Z.:.�
� ��� .
���� ��4 �*;
� �� �
�
4-4. � � � � ' � '�
Chief.' .
:���
�
� � � -ti � .
��� �� � - � - �ei
�
�����.�
�
�
. �-� � ISS I Che'rniCal DIV11001144C.17ill
.�:... ... - r. : ;.�..... - .,-. � ..... . cl_.E.-..� �3,55-42 � _... a, 2 : . _ .� i 1 .d. �.� ,---
� * - � ,- , � v9 5, �
'. Attachnieut:, ........�_- ,.;_rzi,,,,....,,;-1_,....L-...,........i9.1, ..
....... UVb#I..,.../b.51.0
.;��� � �.� �� : Invoice &Certific tions .., -� � �-� �
. . �
-----------� ----�:. --, �
-- � . ...
.� Distribution: .. �� � - -
tc - ,,A
Orig dreisee a
. � .� - -. - � �-- 1....--....-:::::�. ___--
..
, I. . � � -.. . -- ..? � ' � '
1....
�
-- ....: ,i .....1:4����,._:�:-.11',....� 411;14:1;: ..
- '-'� *. ' : "..- � , �
-"- -, � - - ���� .
%; �...
' .:C -
LA� i -... - . :1-,/-..- --..
...
.-s ---",�:-',4 ' 7�����s-�-. � � �. - , -:,. .
� "a.1'.4.--.d% - (--!."-'-�, j'.7s .. -;-"...:' ,,i'.' 7. : .. r.,-....-.. �
...
; \;;X;I:i;�.4r...-_,-4A.. . .. if -':' .. �,./.
, - .... , p... ,.....,4-. � . , ....1:-..1. . � :.� -....... .3. � . ... . .. , - . � :, - . � .. � . :
. ... ........� 4.-3.: ..-... ......:-,., ..,. s . .
. :: t' ������"1-$;-&,--tri41 ' a....��`'''�-��.-''' ; .,-..�-� 4::%.�:::." ..- I .
. .-.g l'
. --
-
bownzraded 0� ( I
. ALAI. (7)
by -^ .Y of 17475
eat 3117 107
6
DRAFT
25 June 1959
MEMORANDUM FOR: THE RECORD
: MKULTRA, Subproject 4?
1. TI)eurpose of this subproject is to provide funds for
the continuation of the program being carried out at Emory Unive
sity under Carl CPfeiffer, M.D. The scope of this work basically
covers the development and testing of new chemical compounds which
are hallucinogenic or otherwise affect the central nervous system of
humans. Certain phases a other problen-is, of interest to TSS/CD will
be investigated.
Z. The nature of the investigations to be carried out under the
direction of Dr.1 Pfeiffer encompasses the synthesis pharmacology
and pertinent biochemistry of potential hallacinogenic chemical corn-
pounds. Testing and evaluation will be conducted in normal human
volunteers.
3. The funds for this project will be ttansferr d using the
as .a cut-out.
4. The cost of this program for a period of one year beginning
1 June 1959 will not exceed $4'1%378.00. To this sum must be added
1
Dowrigra
by trAP...srity o
Jrno 19'
@FMK
37475 n
-2-
$1,935.12 representing a 4% service charge to the
its�co. making the total amount $50,313.12.
Charges should be made against Allotment 94502-75-902.
5.
1 I,
to submit to thin a summary accounting on art annual basis of all
04 has requested Emory University
monies received from the � Also, it has been requested that
any unexpended funds be returned as soon as possible upon the close
of the grant year.
6. The requirement for -:a six months' informal accounting
on the part of the principal investigator is waived.
7. Title to any permanent equipment purchased by funds
granted the University shall be retained by the University in lieu
of high overhead rates.
8. In connection with travel under this project, it is agreed
that the Agency will accept the travel documentation and accounting
which conform with the practices of the University.
9. It is agreed that technical reports reflecting the progress
of the research program shall be submitted at mutually acceptable
intervals.
Downg.rad 4 to:
by euth Tity o, 87475
ano 19
.74-!:11V.kw
TVV-- kesAvtat
Dor.r,r,r
by au
at o
E2
1
1
led to
,7uno
!.!?Di
rir Cod to:
by cut .ority o
e ate: June 19
187475
10. Dr. Pfeiffer has signed the Memorandum of Agree
meat and holds a TOP SECRET Agency Security Approval.
fl
Chief
TSS/Chemical Division
APPROVED FOR OBLIGATION
OF FUNDS: -
Research Director
Date:
Attachment:
Budget
Distribution:
Original only
.87475
�-� ;viotv
the
PROPOSED RESEARCH BUDGET
June 1, 1959 to May 31, 1960
for Grant to Fmory University by
PROJECT A. The synthesis and drug enzymology of possible
hallucinogenic chemicals.
$8300.00
4380.00
USPHS Grant
Equipment
2000.00
Travel
500.00
Consumable Supplies
2500.00
$17,680.00
Indirect cost_- 107. -
1 768 00
$19,448.00
6,.40JECT B. The Testing in normal human volunteers and the.
pharmacology of-experimental-h,illucinogens.
Carl C. Pfeiffer, Fh-,;DM;D., Principle Investigator
Personnel -
Ca51 C Pfeiffer Ph.D.M.O., (Part-time)
C--
$3000.00
3000.00
3000.00 -
,$timds_for_human-Aiblunteers____ � 3000.00
Summer Student Fellows (3 at 6qo each) 1800.00
4900.00
500.00
Equipment
Consumable Supplies
Travel
Indirect cost - 107.
Total of both projects -
WARNINIG NO7 C
TIV ( SENSI INTEOGE:i -E
sot:Ras ANN...9 Ibps IN OLVEO
.:
4000.00
3000.00
)000.00_
$26,300.00
2,630.00 ,
$28,930.00
$48,378.00 �
�
Li 7
PROPOSED_RESEAR CH 13_UDGET
Personnel, including volunteers
$30,980.00
Supplies and materiel
n, 500.00
Travel
I, 500.00
43, 980.00
Indirect Cost - 10%
4,398.00
Total $48,378.00
'ED
Carl C. Pfeiffer
:'.4)-,:'.t.54..T..7.7;.���� ����� �� - � � ' ' :" - r. 1 , - V. ' ' z."-t""j14-i�-it.."-s-,..11-74, ; �
i.
� - vf ....V. �-; at ..., : z
'' ' ...1., k:.�:: V i':.t.'tt .�5.' : sr: . , . " � '
'C'-?�''''''.7.''. 4:4: �'.�.;11. '..,,A�L . 4,:i.�:, ��;:�� ,'--...i.:.';�.. . � .7. ,....../ . - ��'-4....11:,./ � ����1%.,:: !..i. ,i, is. a; pt. -14 ......K. 'i-...1.11...3'.,::� :::;:.
..."
---,- -----4.-- ---,--1..t.... - ...- ��--�-�'..---; -'''7 4.-4.7.,z'' =,.... :4.1--
..,-it. ,:...; i',;.;;;;;;-.-. 4- ,.:-.. � .T-1',' ;:.`,4:..3;',1A.r _*�.� � ..,
..... � . .
. i. *wows.
......1.-:-.;;.,4.-,,,-... ..-tr,,�air... 7.,:kk.,-.;;-....1,_ 4..,.;,...2A,�:-.....c�:,-�,,,12 ,
r.
� � � ' -� .-i'l�i�:�''f.�:�41�-�-...".�.--:1-�.-
'
r . aarr ely In, .0 do .6 .6 yr .6 ...
. 9" 10 ISO es �� .., ,,,, .. a. i.
"c�..t....f, ,_!�,k � -
� � �g� -
v � �'-�' , �N-a - -" 1..7: � � -1 �
t� ���27�-� � ,
;.
� la�� e
� �:���-�
, ...-- . -
� ..-� 11....5-t -.
� ,.t ,.�� .1, J.": . ' 1.4�41. �����-�' � � ...rd. ' C
." .4;1- ...� ��� � I 04 . � .
....- 1 ',.:�;.:-; 12, � i :�I "���.): .4.1. � "
�� .j1 .,�'4! ?' ":".7 ��4-I:1 ....4ss e'''....: 2:.' -; .�:-... I
''3�'-'7.� .;j7,..- ten:
i" - .,.,r..t.s.r� �?z::������ l'" � "" � '
� ����-. ����:, zu .74'.."'� -* ': ..- '
'"r4r � . .
.a 1.�
� III�1
*.�-
/710.02
� , � � . 'et' � � .. �
^ A ��.� * *"."; ���;:,
� a � et,: tf.Z�1'":".;%;:'
. � 0 � `V` � -'t-� -
- � (1) . It is hereby certified that this is Icaviee tro._8 appl.ying to ."..�'?�"."` ";�-� �
aubpro:olet Ift of }21/111:1.4� that perfornee is.. satisfactory, that
- reriloca 1:+re teirg acecmlis,hed in aceerdancs vith cutual, agree-. �-�-. � � � ��
�� Dants that a eeta41e,c1 e.-,���:-.'4a of ths pay-sent-3 6r-4 rocvipti is on ::" � _
-
��,:ila in 5.-SS/C0,0 that_thls bill LS jthit tbd corceet &al that mrea.t
. '�,Cif hal CINT�lt � � ; ." *�-�-
�
� ir.� I
� �� ���
�
���� � -
F
z t�
a: � ,
. �^ �
�
� .- � � � � -�-�
� :
" � *-� f.�*7t'
s
� ��-� :*-1) � - � �
.-72���� ������.:,, ,;: ����
--a � � � � - Dat431
- . 3. : � � � �
%no." �f�z.;������..-1.�- � -
� - s cP,wmIcAttots "�� t.�
.F. -�� � � � - _
4.ft'
r ; .?..`14;�..
�
.--.�':.,1"::�� .j. -1;.' .: ' ,;-� � ....- .
s.,,, ._4. ... -I* �,. : ".��� .;.�: :"..
-:;.: 4..... ....
..:..:, �-� _,....� ��?.� -a
le. 1 a ......: � . . r.S.:.,
- - i � �-� ��� (..-_,...t.y....
,,,�-..,:.-!,...-..- -:.-;----
- -....., .. -- ;,_;-.-:-.-.� � ..
, �
--..... . ..
..!,.................., -%��. Mier, 2Z-S/C-bezie�al. Division .- ---;-�-� . -
.. .:�.
;-..-...----r--- .�'.. -,,:�..,-,; - ;,�...,,-- _ -
... .
- .. ...; � . a?..- -
itl�-;1.�'...
. � �� .1, � -a� ^ - �� �
-0-4 � - - -�� t�-�
^ t. 3;.��*
e;����.....-�...- � - � � ta. - �
� I
..... . . .4.. Or ".. ::-..;'� � � ; � . - � %., .' � .1 !' ' � ' - ,..-. ._., ...
1,2) It is hereby certified .t.viat this invoice applies .to Subproject
la of nall...r0A which Ins duly i*.pproved, and, that the_yroject is 'being -,;:�,. ..
ce...rried out in accord _vith th...a rozorandum datad. 13 April .1953 . . . - - �7.1..
� trt to th4 DD/A, anct..tho extension of this authority in sub.-- ....:-.� . 7... -.
� beVerit -=��-�;,,z:�-� , ;;-.1=1* � . � ..� ..,:-'-'-3, �)---1".-..' t� .r:..--- -. r -. ,-.. ":.. � ..-.�. �.:, . ���� � .: . . .%. . . :14 .; ! .4...,.... ';'.....4 � 0.,...:.1 . � . � .' . ..
. " , . .. 11., . 't . Z... � ;.. *
- ........,: '7;6'4.... ��2`....2*:43--�."..,�� j.iik' . ��� t .. . -......,:. ' � - - � �-ii � raio. � e�'" � ' � '' '�-� � .
i,.� - - 11 . - � .�- %... � C.... _ ��. f ... ...E..- . ....� ..�.. � ...- ....: "-. 4 ...e.?..'1�� ..........-rs.."` �- 3��74...: 7;71 .;.."��:"'"
'. �-"�' � :411 : ���� � 44 . � ". ��3:... i ..., 1.'f'� f :s I '....!-� �� � � ;'..- .....1'� ll- :....
... _,,, ... . � I.". 7... � . ,..:...% a - .". i_ .
� il ; ���� �����i � ....,./ ..� ...... ,-.-4. _a ..: '.--
.... ...r. �Ir.-. .
Research Dimetroia�
. � � -, . � � ;
� -�
�-"t" � �
Ms: � , � � .7..t
e . �
� -f it � , � � .
� . -1; z'"
_ � �
� *2 ; �
�� 7- - a.�'
� . �
: � � ,r -.,/t 9 ������ � " �
� � . �
. _ � _
: : .'� �
�
" � ."��� �'3; �" � *�' � �� ���Si
� S t
t:
ei.-.����,� , �� .
���' - � ' - � d-�
-; � -t ������-,
�
� � ,�
" � � .1 � �
� � � :,�"7 .
. �� � �
. - . . � -
. �
��
. .
�
" Downer da
by w4. hcrl
date Zan
E2
VITIDDITIA
of: �7475
977
Y 187475
MEMORAN1)U24 FOR: slip RECORD
SUBSWT
DRAFT
19 June 1938
: PALTRA, Subproject 47
1. The pOrpOtt of _this subproject is to provide funds
for the continuation ofithe_program being carried out at Emory_
University under_Dr.-_Carl C. Pfeiffer. The scope of this vork
is outlined in the attached_proposal-submitted_to Drs.
and 4. and basically covers the development and_testing Of
new hallucinogenic�compounds as well as certain phases-of other__ ,
problems of interest t-OTSS/CD.
2. It should be that as in post--years, a_consider.
able portion of the total cost of the indicated programwill be
borne by agencies other than TSS/CD.- These include the U.S;-PUblid-
.2b
Health Service, Emory University,
the
and others.
3. The funds for thie-project Vill he transferred using
as cutout in the__
usual manner.
4. The cost of this program for a period of one year, be-
ginning .1 June 1958 vill not exceed 202.00, to which must be
making
added the four percent (4) fee to the
�����
the total amount $50,130.08. Charges should be Made against
Allotment 8-2502-10-001.
o.xnf...adod teliFIDEtalAt The
by eu 1-13ri�f: 187475
Cate- Jun 77
E2 I!tY747A
has requested Emory University to
-1-vitomerripx
. . g
by ant'
eate�
E2 IL
rity of
19
CI, A:4
suJm
them a summary accounting on an annual basis of all monies
received from the Fund. Also, it has been requested that any unex- _
pended funds be returned as soon as possible upon the close of the
grant year. _
6. The recu1rement for a six months' informal aeccnting
QA the part of the principal-investigator-is waived.
_ T. Title o any permanent equipment purchased by funds granted
the University shall be retained by the University in lieu of higher_ _
overhead rates.
�
8. In connection with travel under this project, it IS
agreed that the A.s:ncy will accept the travel documentation and _
accounting which conform with the practices of the University.
9. It is agreed that_teehnitai reports reflecting the progress
of the research program shall-leTsubmitted at-mutually acceptable
intervals.
-10. Dr. Pfeiffer has signed the Memorandum of Agreement
and holds a TOP SECRET Agency Security Approval.
AppROVED FOR OBLIGATION OF FUNDS:
Date:
Attachment:
Proposal
Distribution:
Original only
/
,....;0001(4%=`. � d.xr-c4t-
if
TSS/Chemical Division
DornErat?ri to:
by outhcAty of:
!ate: J'ne 197
�2 IYF Z1; r
. PROPOSED RESEARCH FOR 1958-59 ' LI 7 -
1. Continued testing program in animals and man of the potential hallucinatory chemi-
cals which have been synthesized by or which become available from
commercial laboratories. ow has 30 chemicals awaiting testing in man.
2. 2-dimethylaminoethanol in preliminary trials modifies the ISO-25 model psychosis
in that the onset of symptoms is delayed but in the individual subjects the visual
hallucinations are more frequent. A double blind test of rigid design will be
set up to quantify this effect.
The possible occurrence of 2-dimethylaminoethanol in natural foods will be deter-
mined by steam distillation and paper chromatography.
I. Tests will be made on tamitine and its tertiary amine derivative to ascertain its
possible role as a neurohumor in the central nervous system.
5. The D and 1. forms of lactylcholine have been synthesized and will be extensively
tested in animals to ascertain the possible similarity to acetylcholine. Other
natural occurring alpha hydroxy acids will be esterified to choline to determine
their potency.
6. Continued testing in man and animals of those compounds which may be submitted
by the111125Z-M,. teen .3
7. Determination of the effect of candidate hallucinogens on d-aminoxidase activity
in vitro.
fi://
MING ICE
GE10E
S VIVO VOr
Department of Pharmacology
Carl C. Pfeiffer, Ph.D., M.D.
. PROPOSED BUDGET 1958-1959
Director, Carl C. Pfeiffer (part-Aime)
$ 3,000
Asst. Prof.,AliteCW=4;(fuli)
8,000
2 Physicians (Follows) Atlanta Penitentiary
. .
3,000
3,000
Research Asst.,
3,000
3,800
Technician, sn..
Graduate Sti3dent
2,500
Animal Attend.
2,400
Social Security and.T.1.A.A.
1,020
TOTAL PERSONNEL
Stipends for human volunteers
Consumable supplies
Equipment
Travel
10% UNIVERSITY OVERHEAD
TOTAL PROPOSED BUDGET
VIM\
SF.1:5i WE I!ciitc C
$ 3,600
5,000
4,000
1,500
$29,720.
$.1111_100
$43,820
4,382
$48,202
SOCi '!O. .ETHO'S I OLVED
C>e
-
f- ose,- ��11 � -
SOIY.FIS I
I . .
1-11:,NA:rxs fisc: y---.E-.;,s CI-4LO kVIONs 031,:itkr1:05Zf 'XilaR-31.1147ED
r.KIT-1-R) L'Alf111.452D I ...SATJ.W.:=E
2, JUN
ef1
19 8
I
I
- _ 1
II -II
- 1
fH
/3er 414--
I
_
mmemmum mat cm-Romig
ATTtliTIO1 tihanea Division
:WULTRA4 Subproieet h74 Additional
Authorisation No. 6
61.a.TXT
�
19 june 1958
Vb.ler the-AuthOritl
re.ntod in the neerfinial dAtol
13 April 19534 frOm thaPU to the DD/A end the extension
of Mit tuthority in sutesevent azoortuxia4 Slibprojeet_hi_
yea proviously approved. Under the sea tutberity en-edf__
ditioneb CUI ot 4,54413).Whas leen euthorit4t0 cover the::
eaprojeet's exenr.res (thereby trineug to a total oi 4504130.0
funds oblicated dmrinci FY 50) to be at:zed to Allottnt_
6-250C-10-001.
F0.1 OBLIGkril FUltr4t
Date t
Distributions
CITE & 2 � Add�vseoe
1 - Vs/010
V 1 1r3d/1A3EI
1 - TSSARB
-2 - 7SS/CD
ft
slrXZ
Chief
TSS/Chealeal Division
g 7,� r: S et bv,V.Astit *4;4
J c-re � c= /
hNORY MY- I
Deparrent of Pharraeolou
Dr. Carl C. Pfeiffesijirector
Surncry of Receipts ELnd_gxpezditures for the Period
June_ 1, 19athroufth 14ay 311, 1951
Direct Expenditures:*
Personnel ,
Tellovehipe
BUnan Sublects
Travel
Ewipvent
Expen3b1e &ppUes
448,421.0V
t22, 695.11
6,00mo
31409,00
1)135.45
4,798.37
.250P0.tn.
Total Direct Exynditures 02,058.v0
Contribution to Indirect Cost 11.).?�282
Total Ex--.nlitures
Unexpended Balance as 0 5;31-58-
* See attached Schedules.
Approved:
46 264.0a
DORY UNIVERSITY
Carl C. Pleiffer,14: D. Hush E. Hilliard) C.
Project Director Chief-Accountant
DIORY UNIVERSITY_
ps,cartnant of �Phai-racologz
Dr. Caxl C. PfeLfferi Director
PERSONNKL
Aricrunt
-
Student Assistant
4 100100'
Research Assistant
52.00
Research Assistant
E00.00
Research Assistant
3,000.00
Assistant Professor
1,033.32
Technician
750.00
Research Technician
273.00
481.00
lbI)iUII
Student Assistant
611-6.1
Student Assistant
959.24
StVdent Assistant
1,327.00
Re s e arch Aistant
Technitian-,-777:777
3475.00
Asst. Professor
7,12.00
Instruct4r -
70.32
Technician Specia1-1St
225.00
StOdentAssistnt
loo.00
0radnAt47Assittants
22.50
Instructor
145.00
Social Security
Total Pe onnel _
4.2.24,�2L1A.
k`aLlif.TSRIPS
?envie 4(00.00
Tailor 2,700.00
Fellow 24700.00
TOW. Fellovships
go......s.��������41
WaLan SubJecti-
Date
6/28-30/57
8/23-30/57
8/23-25/57
9/3-7/57
9/340/57
12/5-61)7
1/24-27/5.8
h/11-18/8
A
WORY tnilYNRSITY
Deparireent of Pharnacolou
Dr.Carl C. Ffeifferi Director�,
TRAYM___
Indy' dual
10-1t.Ffelffer-_
Dr. Carl C.-Pfeiffer
Destination
Dr-e'Carl C. Pfeiffer
7�1
DT. CMA C. Ffeiffer
Dr.- Carl C. Pfeiffer
-Washinsion,D,Ci
We-sh1rt.61411a1D.C.
NtAi York City Si
�.
Middleton, Conn.
Chicago and-.
FhiladelphiAL
Total Travel
Ara"ant
111237
110.96
84.37
41844
-245.61
41883
64-.60
4-63`/0
_103.19
14941
183.i0
t1J1.35.145.
!INERNMEINRIMIW
_
"17
EMORY UNIMSITY
Elesif=?Ttment of Pharmigi
Dr. Carl C. Pfeiffer DirectorI-
rta4
MOM-
'Ivo Transducers, Yodel:FT:03- , $ 238.39
Precision IonograPhi- Seielor-rodel. IfE410 1,230.85
Electric Welder 36.0
Physiological pressure transdUcer -
399.1-
neight ' 26.50
iardy varburg� ranoncters, reaction vessels 1,236.00 --_
Glass Yodel7FI=10 Force cable connector,- -
dislaCenant transkluer -7 - = 243.69 ----- -
Steel case_: 159.03
Typcvriter_ 205.43
Typev-riter- 210.16
Tvo dent, To ehairs 551.63
Internal theralstor probe, skin temperature
therwiator prOe-_-------- _200.32, -
Total_Eqpipoent
-Dogs
Chemical detervinations
Batteries
Data sheets
Data pads
rneropmeters
Chemicals
Eriffusion unit
Chemicals
Manual
Mice
Chemicals, glaesvare
Cats, postage '
Chemicals
Culture
Chemicals
Alcohol
Chemicals
Spatalos.. chemicals
Cats, lab. supplies
Cats, lab. supplies
Bottles, tubing adapter
Animal food
Chemicals
Androl food
Chemicals
Amiral food
Cat*
Chemical deterrinations
Freight
Chemicals
Tubes
Research notebooks
EMORY-VNIVERSITr
trtgOrgag&Orant
Dezartnent of Phairlacologz
Dr. Car1-C2feiffer, Director
Record supplies
Felting point api)aratus
Wire, tubiag �
Cats, postage, rise. supplies
Pharmaceutical supplies
Chemical enalysis
Pipettes, atetone,-ligroine
Stainless steel untulas-
Chemicals
Animal food
Xther
Photographic service
Continued next colurs1
ITEM
$ 36.00 Kymograph per
41.93
17.61
3.09 Chemicals .
8.33 Chez-teals
69.91
19.83_ Scotch tape:
5.36
45.32 Misc. lab. supplie*
10.67
31.68 1 Chemicals �
17.37
21.75 Chemicals .
22.23
91.96 Needles, valve, stopcocks
32.57
5.75 -acemicals
1.55 Chemicals
47.86
60.97_ gas (02)
14.83
44.20 Animal food,: cdar shavings
37.70
39.143 rhotographic or
87.73
40.60
46.83 Chanical-detenxinations
4.47 Misc. lab. supplies
38.84
3.31 Reference book
5.88
6.41 RePair rostoid roaSuers
5.00
2.66 ___ Animal food.
26. z
814.56 - Chemicals
54.79
7.81
1 .60 Plyvvol
314.146 Regulator
30.13
41.57 Thernw)eters
81.43
42.16 Reprints
59.65
5.83 Alcohol
2.56
5.80
43.78_ Fharroteutical suPPlies
47.84
19.37 Chemicals �
13.39 Reference took, slides
14.10
24.00 Chemicals �
2.90
41.00 Thernoreters, chemicals
13.94
4.37 Office supplies
10.00
19.57 Table cart
67.35
31.91_ Alcohol
3.85
-- 119.58 Pharmaceutical-suppli
58.55
8.47
�
29.25 Chemicals
21.73 Reprints
31.65
19.37 Reduction ged.r
10.25
2.93
38.91 Chemicals
24.50 Freight
4.23
6.65 Mice
33.143'
21.80
84.91 Needles
24.00 Slides
7.93
155.50 Fork Liver
4.90
26.27:1 Sturditips � .
1.22
7. 68
17.33 Chemicals, tubing, stopperi
23.10 MagAifier
Continued to Page 2.
Iri24
Forvarl frtml PAl&5 1.
Drugs
Electric Motor-
Misc. lab. supplies
Chemicals ._
Apron, flasks, tubes
EXPENDABLE SUPPLIM
AMOUNT -
4. 15'97
. 8.76
37.8k
19.60
4. 35682
Red herringbone tOvelini ';11 9.27
Stethoscope-head, tubing 13.39
Chemical determinations 13.00_
Swivel casters 9.02
Mullmatic pressure regulator
Plastic covers, chemicals
Photographic vork
Ice torgs
Ether, funnels
Freight
Office supplies
Tape
Alcohol
Pkarmaceutical supplies
Chemicals
23-.68 RriaSs
15.44 Chemicals
23.25 Chemicals
11.21 CheMiCals
11.06 Reprints
2.08 Chemicals
5:601 Reprints
3.85 Office�supplies-
8.00 Cate ,
10;67-
Stoppers, grease' test tubes19.03
Ad_apter 3.20
Chemicals
2.58 -
Casters
6.15.
Chemicals
6.56
Forceps, scalpel:
9.21
Bin41ng journals
Reference Book
6.51 ,
Chemicals
2;02�--
Forceps
16. 96
Chemicals
11.17
Chemicals
Reprints
.20-33,00
Misc, lab. supplies
37.79
Chc.Kicals
20.81
Chemical*, flAvsks
14.28
n-eight
2.30
Chemicals
8.55
Funnel
2.59
Chericals
25.03
Folyak vertebrate -visual
system
37.52
Chemical deteirinations
13.39
Freight
2.24
Chemicals
8.78
Funnels
5.62
Helium, valve
18.47
-Miscellaneous supplies
30.54
Choeicals
16.53
Freight
5.43
Ch ca11
eb (^IA
21.16
Chelical tie tem1xt iting
39.'0
FM.
.�
Alumnus foil, &iepcnset 18.94
- PrUSS. 11 12.57
Bottles - . 31.93
Magnetic bars: 3.99 -1
IlAtte cover Z4279
Watch, glasses ehemicals, . _
Stoppers 4.27
Chemicals 16.07
--:Plasksi-chemicals 17.82
16.98
17.01
32.42 .
26.65
36.01
41.43
Cheaicals 8.0 -
1-.80
io.00
--Photographic_service
-:icio
9.50 :_-_
16.63 11 .25
-----
Chemitals
FN.ihnels
- '
206.00
Ant 1foo.i
414.7o
14.n
Prtight
---s-Aniral. foOd'
15.40
_ _TotAt
11
1,.!4_1920A
_
_
RECEIPT
I hereby acknowledge receipt of the following two checks:
Cashier's Check N
The
of $3Z, Z80.67, payable to the
able to th
�
� ��.1.,1
d April 30, 1958, dralvn OA
, in the amount
drawn on the
in the amount of
Date: 44 TA.
�
,s1s"
22 heti 1958
�
)122010.11i14 nal CHIElp FIKANCE
VIA - TSSAodiset ()facer -
SUBMT A.TULTRA,_Eubprojeet 47, Invoice
'Allottentrit 7-25W-10-001
1. II:Voice No. j covering the above subpro3ect Is attached.
It is requested that payneot be made as follevst
Cashier'scec n the amount -of 0a)280.(7 drawn
On
n the amount of $1,291.23, drawn
f;
Zech ebecX should to mnde 1eyeblo to the
. -
� 7,
2. The aheakofS42-01P f-1.0,211-9�44.�������������� ������- ���
� � .� � - � � � �
� �
� � �
�
�
� .
� �
P � �
�
� .
� . �
... � -
- -
1 � - .!*
: � �
- . .
� s � � ���
-
�
�����*�..
�-���.�t -1-.
.1 7, � _ - �
.; .� 1.
� �-��,
r. �
'1174 /-114
�
� �.�".
� �
� �. �
�
. �
4, -I..% .
. .4
�
� . : �� � � .
�
. � .
�
� � ��� � ' �
� ������ a'
. .--� . 4 � - � 2...� 4�
� 4:45' '; 4 � AI � :.� . � � � � � .
� �� ���� V: � .1.2 " ��!:- � �2�'. � � � � ^ �-�
111.21.111110
.. � . � � � ' � 2.
� �� � �� � .
�
r.'�� � �
.�
- � -
-
.�
-
'7-�;���.-..'":"Pi.-.-
. , � -
� ie.
,-
��*����� g
e�Ve �
171 '1 t4: ���
-!�-, �
1.7;-c...A�...z-'!_t-1
.144 p����',7,- � ,aw-a � .
� IV k
� � :C;�
� *�4 *-- �
��� = BECEIPT- � -� -��� 74$ ����� / �
. . .. . � .*-- �
:et:* . � � . - �
- I hereby ackiiowledge receipt of the following two checks; *
: .
A- ' . J� � � � .- � et --��� � � �
?II-. � � � �- ���,...-� � � .� � .� � � ^ .
-
�
' ' t . � - t-:
�-r *
Au 23.
Cash Check No. dated .crtist
-
�
�S.
-
$.16;110.33i -payable to th
� �� . - -
, � - � � itc,���� �I� 4 � -����� ....::2�;.-a�Ow�er,i������ �,-4�� ���-�10 .��������?..4,������=.2.--d. � ��� i4VVF4r4mCohnsig
� , � N.. � - � t..": ��� �� . � �
�
� ��� .Z...���sr � �:�� 4��� ` � .�� � ����2 �������
� ��� .� � � �
. �
7 'drawn oh. -��
in the anfount �
ashier's Check Check No.
t to the
�
.71.4
. � � -
�� � � � � � � �
-
�
":; �a..1�� -1r� ";;" ��� l':���-�. �
. �� � ..07..4 � 40-1. � - � � " ^ ��� . V� .' .
-
--;,
-
a
: �
�
. - � �
� � � ���C
� ;� � � d�
C � '
�
� �� �
.": � � �
�
.6 � ��� : .V�s�
'e � . �.� _`. � � - ���
.
� . � �
� �
. m��=������ os � �
�
� � � .
� � � �
�
-� . ������ � .
� � � ����
. r . �
�
. �
� '47.. .." �
� �
���
. .� . � �
...go. 1,0," AP. _ ���������� 4�-�4114-�
" � � .� � � ��� .. � i; ���� I ;
� s. ��� ���
� �
. � ��
�
� ��
�� �
� � � �� � � � -
�
�
�
�
� *;"
� -
�� � .� ����� 5 . �
4 C ��
..������ � e�
�'�1��
� .
���
� ����.� z!.� ����
" �
-
- .
UVIVERSTTY
� � Departnent of Pharc3e014;g7
Dr. Carl C. Pfeiffer, Director
&"=ary of Receipts and Expenditures for thoe'Pericd
171-nJ1 15thru,aMy 1,_195/.
11
Unexp.--n;led bal .ca My: 31, 1956
Received from Orkgr.,
this period
Total Funds available this period
Personnel
/11112-g-a sub.:,ects
Travel
Eauipaient
Expendable Supplies
Total Direct Expenditures
Contribution to Indirect Ccst _
t281743.75
3,493.00
1,963.50 '
5,56344
4 237.
001.
h 00
Total Expenditures yl 4..,4e 310.56
c
14Pp4-
catei,--ed
Credit Wince as of N4 31).1.957 �vg
(D)ry University vill-absorb this overdraft)
1-6e0 att thed schedules.
Appro-ied:
.
Carl-G1Teiffer, K. Rs/
Project Director
...
icho
'ZIcal
4 11
Emory uniVer8it1Vip4ro
t 377.38
!17,403.00
07,780.38
48,31.0.*
.(1.1t 23 15?
-
Even. E. Bassent, C. P. A.
Controller
4
}WRY UNIVMSITT
Departnent Of Pharmacology
Dr. Carl-C. Pfeiffer, Director,
�
FMISONNEL
EmPloYee.
/-
F
-PfejTfor, Carl C.
Position
Research Assistant -
Student Ascistant
Student ASristant7::
Research Associate
Lab.
Instructor_ _
PteE&or
Stuil en t Astistant
Research Assistant
Technician
Seer etsry
Associate Profcstior
Technician
Technician
Instructor ,
Stildent'Assistant .
Siudent-Astistant
Technician
Technician
Stuient-AsSistant
- Dr. C. C. Pfeiffer -
Social Security- -
Total PersonrAl _
Rxlan Subjects .
expendlturco.
I lare ezzzined
Detej
Chief
TSS/Cbecical Division
Amount
$ 1,13o0.00
600.o0
600.00
6,529.99
1,656.50
6o0 .c
750.00
6�0.03
2.0400.o0
3,300.90
2,125.00
11)333.28
1,465.00
137.50
250.00
156.00
46.67
46.67
12.00
37.20
427.64
$28.1743.0
$ 3 It93.00
4231
Ry unviasra
Date
6-29.56
10-1-56
10-1.56
10-23-56
10-25-56
11-2/-56
11-2/-56
11-27-56
U-23-
11-23-6
12-27.56
-27.57
4-25.5/
h
5-29-57
5-30-57
Grant
Departrent of Fbaroacology
Dr. Carl C. Pfeiffer _Direetor
TRAVYL
Inaividual
-
Dra-Carl C. Pfeiffer
Dr. Car). C. Pfeiffer
r
Dr. CaTri C. .Pfeiffr
_ paqination
-a-rd W4h1r...Gt4m
Cblee&I /11'
P r'
TQtal Travel
D. CO-4
Amount
171.18
2.01
- 238132.1
1775-7.gai
61.45
26369
-38.46
- 151t .52
, 136.15
� 97.06
164.67
112.81
136.54
13!_30
$2&3422.
tiasinta an6 slip`rtivea the sNiblttte
ia
ex-penattures..
GOI11.10
W
1WIL-
cal rm ei
.123
!ISSIcterA 1,151
Date3
C
EPDXY UNIVERSITY
Department of 14-nrmaco1ogy
Dre_parlC. Ffeiftnst_DAreotE
MIMIC '
93-
tl
Itegs Arount
17.66
Drip pans
14
Conversion IWe1 the rmometerl_ 78.88 -
.
16.67
'razor L9.LA2 : 1
Dry Ice sborage a:billet 23.09
50.99;
Desk
36.42
Chair
Stopcocks 3311.75_
111.84_
Treziscribingt dictating riaciline8
Stopcocks 3.04
Strain gftuge Arches 108.15
Rekpiration pump � 395.86
. -,
Freight, customs on ocientific apparAtus 142,71
185.92
Grinder, say 6 1/4" sander _
frei&ht 10.45
67.10
Telephone cabinet
Freielt 4.91
1 Sofa, leather 247.20.
309.00-
Input couples for }.10- -
Desk 50.99
Reinforcins deck top 2.39-
One Model III-DrElectroencepria166raph - -_ 3,235.99
(
Partial refund. on typewriter reporte4 last per �la)
Total Equipnent SW63q14--
zPenditi; CDA
rcs.
Da t-0
SID2,
TSS/Ctezical Divislon An, 23 ;95)
�
Item
Flasks
Cheoicals
Henastats, Forceps
Animal food
Anilial food
Chemicals
Telephone call
Photographic vork
Cbenlca,lck
Rubber tubing, cbemieal
bottles
Desk
Platinul Oxide
Drugs
Magnets
Miltiplosic Personality
inventory �
Tubing, adapters
Office Supplies
Drugs
Alcohol
Dogs and eats
Postage, teleuan,oirugs------- -
WI cards& recording sheets
Rats
Culture caps
Chemicals
Insulators
Hypo needles, thermometers
Bottles & chealcals
Mice
Drags
Riefler clips
Paper roller
Drugs
Drage
Angle iron & costers
ebenicals
Le-undry_
Gas & needle valve
Kr0994
Photevaphic vork
Continued next column
1,313RY UNrvERSITY
Department of Pharmacology
Da Carl Ci-Ffeifferi Director.--
FAnNIABLE RIPPLIES
Ano.int
449 Freight
12+91--- Gasket
84.65 POO bars Ivory sodP
67:71 Dogs '
9.43
6.66
81.25
47.56
/mount
$ 2.42
.5,
. 9.15
305.00:
TelepboAc clit.i: 8,47
-Drugs _ .55
- Postage, drugs, file 26.76
FretCht
:iThermolzeters_ .
-10:11fe blade � 4.55
23-.32 - :F-Fa repr _ . 283.25 --
12.62 pitex stirrers_, 52.74
35.17 _WO of leb.mouSe, shell - 6.38
7.35 - Dsslo-cards 2.27 -
21.09 _ Telegram 3.70- ---7
BOok-- 10.17 ------ --
24.21 Laundri h1.65
7.85 _ ric.1--L-Adit 19.50_
21.51 Mice lab. suPPlies
54.55-- - Telephoseocalls: 5.01 a a
1.71 DOSS _ -_. ; 145.00
170.00 � Book - reference 8.23
--40.73: 100 metal :card holders-- 15.49 --i-- --- - 1
38.73 Telephone :call
66.38 Telephone _call - 12.82_. _
9.79 Z iACcats :. __ 12,02 '
65.05o4:07:7hurAcalei tubing, sp,one - - 50.33
5.119 6- 'Ilics.1,"1/2.4 24.74
29.2/ spprone. e.72cr � 5.89
94.07 FreE4s.
58:32 _ ___ ri,jej, 40 ,.. 3.88
31.14 ' Hitl*L.. sr-..,,culsea v4:1::.-.., 30.00
22416 chemieaVz. 4826;68
4 .5p
.,4
PhotograPhic vor&vis,g 'VII, 32.5� 0
Chealcal determinonatrAs 11-2 - ! 21 63
LI -
301482
20.32
5.10
Chemicals, lab. Oextts 21+50.
Balance forvard next page
'464'
1-1�52 StopeockTL,FrOta
3.12 chemicA18 40.32
40.15
18.05
31.72
22.56 Chemicals, flask4
85.64 Cbwiceis
4.00
1.99
14.13
Pate 2
Item
Continued from Pas4 1
Fl-eight
Miscellameous lab. supplies
Alcohol
Dogs & eats
Drugs
Chetuloals
AnimAl food
Tubes
Bottles
Cheniclls
MORT UNIMSITY
LITENDOILE-SUPPLIZS
4,74
30.13
3485
C1.00
4.48
21.14___
17,67 -
lilt%
22.92
Service typevritor 14;58
CheAcale 72.55
Record books 16 2----
Desk sorter 3.81
CheLlicals 20.96
Mice 62.50 -
Pipe vire _02
Total Expendable SuPpliesA,
it A
t4.:47 o-c,
wtLL44.1
1)ed
,p9 4,24,
41t!Pro
�62
444's
0,21
PeGo,
the 6:11
6.4)4_
1'04
" �
_
APR
:t 4,1958
1
1
-
Lt:001
ALL,.."1-1
CtislAC;.*:".(0.7.3 0111.IGKriO3S CIET-L1 I 1VZ
Lic.g.TDP1) 1.7.C.Fi-6.D
5-2A 94'
I
t
'
Ti
I
-1
1
-
24 May 1957
MEMORANDUM F013: CONIPTROLLE11
ATTFN rums Finance Dlitsion
SUBJECT: MKULTRA, Subproject 47 Additional
AuthorizAtion No. $
Underthe authority granted in the memorandum dated
13 Apr111953, from th-CDCI to the ODA and the extension of this
authority in subsequent memoranda, Subproject 47 was previously
approved. Under the seine authority an adentional sum of 550, 351.24
has been authorized to cover the subproject's expenses (thereby
bringing to a total of 550,357.84 funds obligated during FY 57),
to be charged to Allotment 7;450210-001.
APPROVED F01110131,10ATION
OF FUNDS:
Pr
lifluts;pfdi
ilesearch Director
Date: tAy 29 1357�
Distributtorit
Orig & 2 - Ad3resses
SIDNEY GOII-LIEB
Chid
SS/Chemical Division
;,:�.:~! ,,-! . -E�
zect._.
(to t 3! � � . erif
1 - TSS/OC
I TSS/SRB
2 - TSS/CD
TSS/CD:UP (24 May 57)
ts....
cled to?
ty .11orIty
e ;F:Lie
CL WI 187475
MEMORANDUM FOR: THE RECORD
SUl3JEC f:
MKULTRA, Subproject-47
. �
1. The purpose of this subproject is to provide funds for
the continuation of th-e-oograrn being carried out at Emory Uni-
versity under Dr. Carl (C. Pfeiffer. The scope of this work is
outlined in thattached proposal submitted by Ors. Pfeiffer.and
41Aand basically covers the development and testing of new
hallucinogenic compounds as well as certain phases of other prob-
lems of interest to TSS/CD.
2. It should be noted that as in past years, a considerable
portion of the total cost of the indicated program will be borne by
agencies other than TSS/CD. These include the U.S..Public Health
..�ervice, Emory University, the "'"ezt and others.
. The funds for this pro
manner.
will be transferred using the
, as cutout in the usual
_
4. The colt of this program for_a p.
*** -o ty*c-N
��
� ''- �
������ I �� � � � et. .rip,
����;.:34 ��� � .
1 1-1.!,7-$�;.�;��.7/47:: t�.� � l� � i�� ��� : ��� � �
��
.it� i��� �
.���
. dr, ��� twilt la., .91 "4.5.:-�-��� 4: 17.1.4nti.k...,
v�'"*.���je.
. � � � do. �
,w
c4�6-.1-� ��.
For services
9? -7
$16,43
ANIV
Z. CERTIFICATIONS
� �
(1) It is hereby certified that this is Invoice N. 4 applying to Sub-
project 47 of MKULTRA, that performance Is satisfactory, that the _
services are being accomplished-in atcOYdance with mutual agree-
ments, that a detailed agenda of the payments and receipts is on file .
In TSS/CD, that this bill is just and correct andAhat_payment thereof
has not yet been made.--.
ActingChit, Chemical Divis-Gri
Date:
(2) It is hereby certified that this -invoice applies to Subproject 47
of MKULTRA which was duly approved, and-tEat the project is being -
carried out in accordance with the inem?randurn dated 13 April 1953
from the DCI to the 1313/A, and the extension of this authority in
subsequent memoranda,.
Research- Director �
Date:
r���,���
BLI CA,1%;Ci:3
i
L10-1! I.
3-7 ATEll
20 ii9Usl 1,64-4--a4-$4541-44s' l 1 4.01.14_
ate #
C JUL
1956 0./
/4� ei6e!
12AS s:
_
�
-sr
_1-
6-.1'7111.
1 June 1958
MEMORANDUM FOR: CoMfTROLLER
�
4.
ATTENTION t Finance Diviston
SUBJECT -
MKULTRA Subproject 47#
Additional Authorization14
I. Under the authority granted in the memorandum -
dated 13 April 1953 Iron: the DCI to the DNA and tho extension
of this authority In subsequent memoranda, Subproject 47 was
previously approved. Under the same authority an additional
6um of $49,299.12 has been authorized to cover the subprojects*
expenses (thereby bringing the funds obltgated during FY 56 to
total of $38,174.31).
2._Thts expenditure 3bou1d be charged *gains% Allot-
ment C-2502-10=K11. -
I CERTIFY 1-AI FUNDS AtT
cvms.cr /93y
04.0 se To rAttargra it5
AUTHORIZING OUKER
ptstri:button: r.11
OrIg & - Addressee
- T�s/OC
TSS
1- TSS/S11B
- TSS/CD
TS-S/CD/4444(ilun oe)�
SIONLY GOTTLIEB:Chia,
TSS/Chemical Diviston
APPROY CD FOR
OBLIGAlgON OF FUNDS:
esearch Lireetor
Date:_
� � ' '
* ' �
� '..
.. - -,,:"; -� -'� % .. .
� ���� -�-...7.---��"'i�::,�'..; '�
;:. -A.--.:��.:t.:.�.'�: - - A
. . ��
� . - � : .N. . - - . .�
.
����! � i%
� �
� � - � � -
��� �
��� ����
�
-.. � erry''"
ROOM IG I BUILDNG
�
I
-,������*.��et00.4041��"._...
-
l'Ame rs -24 I CM..1eS.r u X 4 VT,
10111:g 11A1
� - �
Asko*. �������* *or dr .41�� �J��.-....n.r.....c,..,1�01,�.-**�.********�������������������*............ �
� � �
al�-�111
�
�
0.� 'v.' �
Ili Oil
=NT
�
187475
ittKsACS;r'
DRAFT
7 June 1956
AIEMORANDUAI FOR: THE RECORD
SUBJECT � MKULTRA, Subproject 47
.4%
�
1.t.The purpose o! this project is to provide funds to
coatinue the research program conducted by Dr. Carl Pfeiffer
at .F;not-y-Ign-i-ve-r__�sity. This program is designed to exploit all
the knowledge and facilities available to its director in pro-
viding answers to specific questions of direct interest to the
Agency. In addition, those areas of basic knowledge required
to provide these practical answers swill be-developedj It
.r should be noted that although the attached proposal t escribes
the facilities which will be used in the stwiya� the ,rogram
itself was deliberately described in general overt terms in --
order to comply with its unclassified slat t.s.
2. In view of the above it_is desire 1 to describe more
specifically the various phases of the general program here.
(a)
,P.,5 to: cc;
no:Ity or: 475
.70ano 197w
A relatively small part of the program
will be in the fundamental held of the
relationship of structure to activity.
This basic study will be of an overt
nature and will serve the puepose of
iraintaining cover for the
support of the program. _
".�'..tol
187475
"tioz.:167ncleit to �
*ut cTity
eate: June
187475
(h)
the
_
���.:
"*.Vga_hylT44,44!,04,2,44,AW
I
A second phase will be represented by
an extensive effort on behalf of Dr.
Pfeiffer to find a solution to the re-
quirement for an anti-interrogation
drug. This requirement was laid on
TSSiChemical Division by another
�si
Agency component. �
A third phase of the program will
provide screening and evaluation
of compounds submitted by TSS/CD,
including the phases involving tests
\�in human volunteers.
The funds for this project will be transferred using
as
cutout in in the usual manner.
4. Costs for this program for a period of one year
beginningl June 1956 are estimated to be $47,403.00, to
which must be added a four percent (4.-rc) fee to the
making the total amount $49, 299.12. _
5. The -=.1,has requested Emory
University to submit to them a summary acco.anting on an
annual basis of 211 monies received from the Fund. Also,
it has been requested that any unexpended funds be returned
as soon as possible upon the close of the grant year.
6. The requirement fora-six months informal
accounting on the part of the principal investigator is waived.
7. Title to any permanent equipment purchased by -
funds granted the University shall be retained by the
University in lieu of higher overhead rates.
rteed
L7 athol
0: Jur
.Aar'
18 47
187475
r:ohci to: ilf5646C�
'by Wat orily 18747
date: June
CL B 187475
-3-
�
8. In connection with travel under this project, it is
agreed that the Agency will ak:cept the travel documentation.
and accounting which conform with the practices of the
University.
�
9. It is agreed that technical reports reflecting the
progress of th. research program shall be submitted at
mutually acceptable intervals.
--'�Attachment:
Proposal & Budget
Distribution:
Original Only -7TSS/CD
187475
k72 l'CLfY 13745'
TSS/Chemical Division
APPROVED:
t'
-lidney Gott]. Chief,
TSS/Chernical Division
APPROVED FOR
OBLIGATION OF FUNDS:
z. .-
11esearch Director
(Date)
,v r. � -
,4,11.4/46-04XiirN4.4
I
I 4. /1-(1-6._
D41:gar
'by flu nority : t37475
gil
eate
�2 ,f.PD
� CL BY187
/5
-
PziOPOSAL
It is proposed to continue the work at Emory University
which has been conducted during the last two years by Dr. Carl
C. Pfeiffer under thelinominal title, "The Plwrmacological Screening
and Evaluation of Chemical Compounds Having Central Nervous
System Activities."
The program at Emory is necessarily divided into several
parts, some of which are supported by grants other than that of
the it:r.S7.- ut Nthich are operated as integral parts of
the program. Other agencies who contribute are Emory University
and the IT: S:-PubliE'll;alth-S4-1:Viee.
Facilities which contribute a major portion of their capacity
toward the program are as follows:
I. r;.-42y..,...),-,,,,Atratetion Laboratories at
Emory University under_the direction of
� 41077,1:
rov.- :-nied to-
ty
eat :
CB
of:
1977
N'europharrna-cology and Electrophysiology Labota--
g-torie-f_at Ernory University under the_ direction
of
87475
-40`...14110
r4vtl-IgINT%
to: C^' OF.IITIAL
17 out .Ity e 7475 j
date:
' 18Z441
4.
(2)
General Animal Pharmacology Laboratories at
Emory University under the direction of
Professor, Carl C. Pfeiffer.
"I
Behavira1 Psychology abbratories (Animal)
under the direction of the Department of
Psychology at Emory University with�auxilliary
animal testing laboratories under the direction
of
In the Department of
.Pharmacology.
/. FZcilities for preliminary human pharmacological
testing at
G. Facilities for testing in normal human volunteers
at Atlanta Federal Penitentiary directed by
Professor Pfeiffer.
The general program to be continued by these various
facilities is the discovery and complete screening and testing.
.of a number of materials capable of producing alterations in
the human central nervous system which are reflected as alterations
11":40ecd to
17
etc: :uac
E2 1.!.:N71
; CL
EIIIIA
18747' teeeetk-s-Aw
;
7475
"
(3)
Li?
in htfrnan behavior. Such fundamental research on mechanisms
of action and structure-activity relationships as is necessary to the
consistent productionof such materials will be undertaken as re-
quired in addition t� the practical evaluation of Ahem. Compounds
from many sources will be evaluated in addition to those of special
interest to the
Several particular projects for the coming year have.b en
discussed with the
representative and plans are
being made to carry these out_in_addition_to_any_others which may
arise during the year, these particular projects-are as follows:
to: (C:r
by
at: :\c 1977
-
I. ro evaluate the effeets of large dcses of
LSD-25 in normal human volunteers.
2. To evaluate the threshold dose levels in
humans of a particular natural product to
be sup lied by-th This
.evaluation presents difficulties of a nature
which makes it a unique problem.
3. to evaluate in human beings a substance
which we now believe ha= the ability to
counteract the inebriating effects:of ethyl
alcohol.
1111AI
475
s
Anis
7475
by
da
�
F2 IMITET: Cis 8 187475 9 PROPOSED BUDGET 19564957
iWNMW Grant-Ao-Emory University, Dept. of Pharmacology
Carl C. Pfeiffer, Ph.D., M.D., Principal Investigator
�
pkAftect,Ast4::kizAri
June 1, 1956 - May 31, 1957
PFRSONNEL:
Asst. Prof.,
$ 7,200
Asst. Prof.; 1
6,500
Consultant, Carl- C:-Pfifferit:2 1
3,000
Research Asst. Aty'
3,000
Technician,
c,...
3,000
Technician, 1/2)
1,600
Technician,
3,000
Graduate Student
2,400
Secretary (Part)
500
Annimal Attendant
1,100
2% OASB
524
*5% Retirement
835
total personnel
$31,500.
I-Stipends for Human Volunteers
(Atlanta Federal Penitentiary)
$ 2,000
Consumable Supplies---
$12,094
Equipment
6,000
Travel
.11500
$ 9,594
10% University Cverhead
$ 4,309
Dorle2 to:
ty n-v...oLr!ty o
---
.
$31,500
$ 2,000-
59,594.
$43,094
.4,309
TOTAL BUCGET $47,403
7-�
FAIRY UNIVERSITY
rtnent of Vharnacology
Dr. Carl C. Pfeiffer, DirettOr-
. .
F.
Suanxry of Refeipts e.nd ExpenditureS for the Periol
.n.ine 11 1955 thr64Sh )11Y 31, 1
Unervniel balance MY 31, 1955
Beceived frol this-reriod.
Total AIMS avallablethis ported
Direct ExTenliturcs:*--
__
21,53844
Huoan sUbjeets___
106A00
Travel
1,651.45
Equip:lent
18,669.43
ExpenclAbla- upplles_
5,439.6
Total Direct ExpealitUres
$ 41665.
Contribution to Wirect Cost__
Total E5Erniitures
Unexpenied Balance as-of my-31 1956
* See attache4 schedules
44.
Approved.'
242
$ 51/21..01
�
Carl C. Pfeiffer, M;.D. 4 Evi�, E. Bessento C.P.A.
.COntroller---
�
$ 161.65
MO.-10-
$ 51,964!9,
Tnory Univ roity
Project Direttor
1 have exa:_ined end approved the submitted
expenditures.
If
Chi '
Date TSS/Chezical Division
i i
Er..21.0y0e.
HurlIn Subjects
DeIartmat of Ybartocology
Dr. Carl C. Pfeiffer, Director
friIRSOMI.
Position
Lab. Witt
Asst. Professor
POfessor -
Student Research Asst.
--steent Rebe4rch Asst.
Technicien
Reseckrch Assistant
Student Asst.
Instructor
-StUdent
Student As St.
StU4ent Asst.
Student
-Student
Student
Instructor .
re.-c. C. Pfeiffer -
Sooial Security
Total Pereomel
$ 479.50
6,799.92
3,000.00
800.00
1,800.00
2,620.00
800.00
499.
2:916.62
499.98
499.98
100.00
15.00
31.00
11.2,
200.00
150.00
245.71
421,538.94
105.00
expendituree.�
I have examined and a;proved the sulCmittect
rate:
'IDRUY C alEB
Cb
ISS/Chemicallftv!cion'
ilUG 5 1955
r,
-
�
Departmant of FharLatology
. DroCarl-d6Pfeiffer, - Director
,� - -a - -
tinVF1t.
Date
9/1/55
9/20/55
9/20/55
9/20/55
9/23455
9/23/55
12/21/55
1/10/56
2/10/56
3/756
3/28 56
5/1 56
5/2 /56
5/31/56
Dr. C. C. 'Pfeiffer
Dr. C. C. JICiffar
, r, a
re3A.InNx,10n
N1llFev111e, Georgia
- -4 -
.Iova city, 'ova, Pirneapolle
gine: TT.
Dr. C.C. Pfeiffer
Dr. C. C-Pfeiffer an4-41�,
Dr. C. C. Pfeiffer
Dr. C. C. Pfeiffer
inicottrl.p.r:' � �
c. cite
Total Trave1--
1
Amount
11.40
105.81
- .-
254.12
61.80
96.96
51.55
231.29
100.91
103.16
196.55
98.66
99.16
. 73.22
16146
$ 1,651.45
I.
I hare examined and approred1hetubnitted
CXpe:Iditures.,
Date:
14()12
SlaiT
!of '
TSS/Chtical Division
is36,
�
I
Item
�Depeirtment of Phammeologi
. Dr. Carl C. Ffeifferi Director
�WIS1141t SUPFLtrl
,.s..Amount _ Rest'
Needle valve
CherIcals, stop-r5 anti
stopcock
Dogs
Tape, Ohre, celeuose
Alcohol
Staples�"vriting pen
Collettion carrettc tubes
Transformers
Chemicals
Chenicals
Drugs
Mice
Chenieals
Long distance telephone:_
Mice
Laundry
Stationery, tape, mineo
paper
Mice
Launlry
Freight
Chenicals
Paper, rubber ban3s,
DroZe
Alcohol
Chemicals
n-Isnifier� filter poper
Stirring roek
Chemical.
Babbits
Drug testing
Porcelain halls, chemicals
Resistor'
Cocaine
Gum
Mice
Tubes, electronic
Cabinet/ sIKIn9amined eni
Laundryexpenditures.
e
labels
22.15
20.00
wipes 17.18
3.20_
--2.75
1740
52.51
16.28
23;04
13.63
111.26
21,89
6,11
187.46 '
28.13- -
-������^. -
11 3.98 Bottles, stirring rods,
chemicals
Antnal Food
-Animml food.
' DruzA
o Bottles
Chemical deteepinations
Chemicalto-glassvars
Mee �
-Pace
* Acid'
Tank regulator
Drug testing
Actylene
scissors h-stethoocops-
Pulleys
- Electrical eupplicsr
Glass-I:aro
. 18.00 � Chemitals, glassvrs_
21%.2h Plastic coatainers
311-09_:_0xycaritteycloprolt-ne
10.52 .--regulater
� 21.95-7 -Siliqr platims solution_
Gqinta-pitt
32.90 7 Chemical deteroinatioas
Ayovit .
56.1a
149.101
13.02
12.90
5.55
6o.k6
2.33
41).64
13.96
5.3o
9.79
15.45
5.00
26.04
27.67
95.55
6.18
V1.6 4 2 '
5041
aPPr 2013 he
si
Chief
?SS/Chemical-Division
AU&15
mc
pottso
FbotoEraphic York
Rabbits
Fepair typevriter
Batteries, therm:ga s,
druEA
("Mineola
Syringe
Lab. tools
Bicycle the
Chemieals
'Chemical determinations
Antral fool
La unary
AkIlltfd
Sub-total
333.30
149.89
18.85
13.28
42.*
15.00
5.04
58.6.1
51.5,
76.72
78.02
101.99
76.63
15.45
10.30
21.01
50.00
13.50
39.1h
16,15
23.05
23h.ce .
5.o
3.45
2.41
2(.86
26.78
67.77
50.6
14.
01200.92
I
Ittin
11-.11ance Ford
Che:nleals porcelain balls
Ceiar sbevfirings
Glassware, stopreeche-Acalia
Motor, cabinet, lamp
co Cmnfrt oil ecap :
Antral food .
Glass cutting discs.
!Jr, cellulose wipes
Rabbits
Li
Syringes
procee9ing
Chenicali
Mice � �
Antral food
Laudry
Drill rode bran plate
Chcalcals
An-pit:fiefs, bulbsw.ters
Chemical 'deterairatiors
iirocessing
CM:ale:AU � �
Classvare chemicals, tubing
t17- -75s'
2 a.
ECVENTI-VILI? SUPPLIES
lonotuit Itez
�
43,200.92 .1.011S dietance telephone
, Pike, flash-o-lens
28.39 01Assvare
� 10.30 FLIBI iv:ceasing
104.34 Sensolits 'wire , 12.41
35.31 Freight, postage 41.73
12.75 Photographic 'work 103.50
� 67.7f � Fiht 4.50.
27.131 Tublr.g� stoppers
17.10 -= Cord, bras s rod ,
10.30 Plif.dostat
10.1k Drugs �
15.58 sc.,record supplies
41.68 . pltxtelttsu - �
1031oa_2_CApsu1es 30.90
15.45 Anit11.1 food � 13.02
26.16 �: Syrinzest needles
20.08. LawAry ,
29.08 GlasevAre, thersicals, tubing
� 42.73 Insulators wire
111.03 Bicycle tub'
' Annunt
�
13.35
17.65
123.25
6.00
19.08
12.46
1.20
3.00 _
30.00
46.06
34.46
2.60
32.7ti, CheMiottls 7.567
35.50 � chemicals 22:01
3.00 DIta recording-Supp110.11 42.00
. 10.15 ' �
380.6o Total. Ex. per...lable Supplies' t511,139.65
Ceirica pi.,9ss 2060;._ . '
Freight 1.99
raTA 13.28_
liator rount pulley 77 - -
Chenioals ...... � � � - - 14.63 .
Tabs tester, �ubsse,-' wenches 5.88
Yialse the-Tic-Ilse cotton :'' = : - 23.7k
Xisc. record supplleE 30.64
Pipe flanges & rod 2.03
Dogs � 25.00
Spon7,6es, drug; 24.40
Taipe 6.46
11,otograph1e 'work 52,50
Daatal drug 4.02 - '-
Tracing pap-Ir � 10.61
FDA 14.99
Book - tab. referents 13.21
Laualry 29.k6
Chfmical deteroinations 20.60
TA.Undry 16.71
Fieight h.39
Antral food 23.18
Chemical s 17.5%
Tensolite 3.28
_ Anta2 1... pao4 48 41
. ,
it liatro eratinsd a:A appzozeJ the
r/ponditures�
"
rito Issicuxical DiViEriO4
406'15
1956
Cazif
EMORY VilVERSITY
DEFARTKENT OF PRtRilAcOLOGY
STATRYNT OF EXPENDITURES FROM
'GRANT AS OF JANUARY 31, 1956
. CATEGORY . ALLOTMY.NT _ FAFENDITURFS
__. -_-.
to- -
Personnel
$301227.00
$21,985.82 (Approx.)-
Travel
...
.1
..
- 1,500.00
914.84 -
Equiphent
2,537.18
6l000.co
Supplenent*
8,000.00
7,699.25
Supplies
2,0914.90
2,573.69
Overhead
3,982.10
2_1651.52 (Approx.)
TOTAL $51,803.10 38,362.30
BIJANCE as of Januqry 31, 1956 $13,010.80
Suppleoentary Equipment allowance for purchase of
Beckran DK-2 spectrophotor4eter.
Grant
_Derartment of rhar.luclrolea
Br � Carl- C.- Pre itferi Dir*:.'eter
"EQUIP1,7AT
Item
Nriso-eardette Conpleto -
Flaw atteebnent, Burner etapaardt
Johnson-Kries Stereotuxie
Lathe and attacbLents
Stop 'watch eai bolder
2 telc-therax-Nztar-pTole
IWZ SpectroPhotowter
Witionkl cost . exebanfp ofpratplifiers
Dyrka-puzsr � . �
Stirrer
Utility cart. -vapor 'limp, balance circulating sysien
F06.rsisavj Bench,
Tke drive eAtachwnt for Speetrophotoivter -
Lab. jaek
Freight on equIpmeut------
Offiner Eleetroeneeitalograph-8 channel
2 Hotpoint refrigerators cu. ft.
Typorritiar
Refractozaeter, B & L
Kodt,lt - K100, leas, *toicpbotoi- projetor
K-100 viever, 15 tm lens, projeeto-_ealtor splicer
&pox tape recorder
Convert 3 Tele-tbernooeters
Total EquipDent
ktiOunt _
816.21
545.90
234.88
757.0j
22.b1.
159#0
70699.25 -
10�20_
31.06
66,95
476.89
96.74
29840
36,93-
62.88
352.93
683.82
378.24
715.85
687.56
103.66
131.30
83.31
18 669 143
�
expenditures.
I have ezamin a .na apprea v the sulaittea
41/6* ir
1956
�
S
Chitf
TSS/Chealcal Division
���Stry.-
-. �
�, =.�.' �
� � � :- �
=
- -
�
111:*;CLASSIFIVD CO:yrIDENTIAL
a (SLROCR WILL CIRCLE CLA AT ION TOP AND
�
CENTRAL INTELLIGENCE AGENCY
. � -
TO
1'
F ROM
OFFICIAL ROUTING SLIP .
_
-
33. Octob r 1
ITIALS
- .
APPROYAL U_A INFORMATION SIGNATURE
ri ACTION EiTT DIRECT REPLY � TJRninti
�A COMMENT r7 �1 PREPARATION Of REPLY LI-3 DISPATCH
Fl J CONCURRENCE 1 13 RECOMMENDATION LJ FILE
Re/narks; L
r L7
SECRET CONFIDENTIAL ' UNCLASSIFIED
roc it li O. .) (LA r/..-10.4 i. ...Ii ,27.4 mity 14 ustil.-- . (40)
i NOY 53 .....ctr -I is. scituottai raismoi arm' 11.--uca II
. � �
� �
EYNORANDUM OF AGREEMENT
The purpose of this memorandUM Of agreement Is to set forth the
mutual administrative responsibilities of the principal research
investigator and the sponsor. Therefore, it is mutually agreed that,'
A. The principal investigator shall submit to the sponsor, at
six month interval*, an informal statement of eipendituresof_monies:
advanced for resear0 activities. It is requested that the
submitted in essentially the folloWing form:
Personal Compensation
(Salaries, Subject Fees)
Equipment
-
Supplies and Services
Contingencies
Overhead
B. It is understood -that any travelexpenses incurred in the
furtherance of the research program vill_be accounted to the University____
in a manner consietent with its established practices and policies._
C. The principal investigator shall submit to the sponsor
semiannual reports on the tech/11.gal progress of the research covered
by these fund
D. Title to any permanent equipment shall, be retained by the
University in lieu of higher overhead-rates. .
Date:
�
EMORY UNIVERSITY
EMORY UNIVERSITY. GEORGIA
Department of Pharmacology
October 5, 1955
As one � the favored recipients of grants from th
� I wish to thank you for the support of
our basic chenical and pharmacological research program for the past
four years. It is our hope that our close relationship with the
interests of thet0=044214a10,will contanue since We 4urselVes are
continuing to expand our interests in this field.
Since ny last letter I have obtained an accurate quotation on the
Yodel DK-2 Beckman recording spectrophotometer and the items can be
listed follows:
as
1 Yodel DK-2 Beckman recording spectrophotometer
$7,475.00
1 "Tine-drive" attachment for above
290.00
�tax I
233.00
3% Georgia sales
This equipment will be of extreme valve to us in our present re-
search and is, I believe, a basic instrument for our present research
proran and will continue to be utilized in the interest of theiMIN43
for many years to cone in our research at Emory University.
Yours SineerlAY,
/
Carl C. Pfeiffer, M:D.
Professor and Chairman
OCP:ba
WARNING NOTICE
SENSITIVE INTELLIGENCE
SOURCES AND METHODS INVOLVED
MEMORANDUM RECEIPT
A
SUBJECT: Cheeko , Transmittal of
I hereby acknowledEe recei t of the following:
Treanurer Cheek No;
�
fo
24 October 1955_
�
In the amoun
dtd 18 Oct. 5
in the amount of 20 fonplAk
on the
Please return signed copylies) of this receipt
To
FORM MO.
36.6i
MAR MA
. _
-
4.
SIGNAIURE OF RECIPIENT
1?;grirr
----1
DAIE ACCESSED
OA1E
iwrfucou,4 ca. trAna D1VISIO
-
VIA t ISS/13144A Officer
sta.ria z MitZtk Subproject 47, Invoice 0,
Juto .t.�tent 6-250240-OA
-
1. irryOice 13 1$ attaohed covering Ma extra wItiprojec
It Is rvilevtri thst per-ent t4 mds follovst
oft a payable
A% ono
f t4jOY).00 and t�ha s.%lond check for
9, to ths
ir.t .aeount
$,P0.01. �
_ 2. Both elooks elckild b. feria-rded to ales ahrtie.,e1
Div-leiorts throtazh_TSS/Budget qficsr, rio later than 21. October -
1953. �' �
). Thitt invoice x'eprestnts the balance of the total-inti'
clIrre.atly atithoritcd under Subproject 47. 110vqyort eineo it is
anticipated thst, atkitticinta YI 56 funds vill b hlizatei unlar
this ravroject, the files of Subprojcot 47 Eihoufd re'aita open. �
&Lo �gnats
� . eLtiot
iss/atziosi.Diftision
A tie cb�->errts ,
Invoice & Certifications
.4% 16 �
Di atrittit IOTA 1
arls & 2 - iddristoe _
- 1 - eoxptrolier
1 - !SS/YAM
TSSAD - _
rn
TSSAZW10 October 3)
� �
�
(l). It is hereby- certified thtt thittlis Involoe 13 applying to
Subproject 47 of MKULTRA, that performance is sttisfactoryi-that
servIcea aro-bstnuacco;mPliihed in accordtncs vith
manta, that 'A detailek-agenda Of the payments and viceiptivis 011,-
file in TSS/dD, thtt this bill�le�just and oorrect_tnd that payment
thereof haa_noty,lot been rad41.-''.--
�
Datei
Chief, TSS/Chemical Divls104
(2) It is hereby certified that this invoice applies to Subproject
47 of %ULTRA irhich 'OR dull approved, Auld thtt:the project la being
carrird out in accordant4-Vith the MeCtandum dtted-WApril 1953- .
front the DOI to thi-DDA, tmd the extension of this' authority in
&VW/event memoranda. -
Eesearch Director
Date?
- I ..� A:0 FE:61.77:: FS �
I_ � _1(-0,-s-ii:e74.75401 4 az-trjoe---
I 12 ac,r5
�
"p"
2,..7
3 1.1:1:1 C.7.:-$
-
1.7
-
4
Al Th1 101
COM?
26 Ceptezber 1955
tal"AltiMTA IcEsCa